MA34897B1 - Formulations d'immunosupresseurs - Google Patents
Formulations d'immunosupresseursInfo
- Publication number
- MA34897B1 MA34897B1 MA36170A MA36170A MA34897B1 MA 34897 B1 MA34897 B1 MA 34897B1 MA 36170 A MA36170 A MA 36170A MA 36170 A MA36170 A MA 36170A MA 34897 B1 MA34897 B1 MA 34897B1
- Authority
- MA
- Morocco
- Prior art keywords
- api
- immunosuppressors
- formations
- compound
- solvate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Communicable Diseases (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
La présente invention concerne une composition pharmaceutique à phase solide comprenant un ou plusieurs excipients pharmaceutiquement acceptables et un ingrédient pharmaceutiquement actif (« API ») qui est un composé de formule A1 ou A2, ou un sel, solvate ou hydrate pharmacologiquement acceptable de celui-ci, dans lequel l'API n'est pas exposé à un composé basique.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11150431 | 2011-01-07 | ||
PCT/EP2012/050151 WO2012093161A1 (fr) | 2011-01-07 | 2012-01-05 | Formulations d'immunosuppresseurs |
Publications (1)
Publication Number | Publication Date |
---|---|
MA34897B1 true MA34897B1 (fr) | 2014-02-01 |
Family
ID=44022942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA36170A MA34897B1 (fr) | 2011-01-07 | 2012-01-05 | Formulations d'immunosupresseurs |
Country Status (35)
Country | Link |
---|---|
US (3) | US20130273161A1 (fr) |
EP (2) | EP2661261B1 (fr) |
JP (2) | JP6111202B2 (fr) |
KR (2) | KR102166885B1 (fr) |
CN (1) | CN103458877B (fr) |
AR (2) | AR084801A1 (fr) |
AU (1) | AU2012204835B2 (fr) |
BR (1) | BR112013017302B1 (fr) |
CA (1) | CA2823616C (fr) |
CL (1) | CL2013001979A1 (fr) |
CO (1) | CO6761402A2 (fr) |
CY (1) | CY1122182T1 (fr) |
DK (1) | DK2661261T3 (fr) |
EA (1) | EA026144B9 (fr) |
EC (1) | ECSP13012812A (fr) |
ES (1) | ES2751920T3 (fr) |
GT (1) | GT201300178A (fr) |
HR (1) | HRP20191842T1 (fr) |
HU (1) | HUE045612T2 (fr) |
IL (1) | IL227094B (fr) |
JO (1) | JO3619B1 (fr) |
LT (1) | LT2661261T (fr) |
MA (1) | MA34897B1 (fr) |
MX (2) | MX357304B (fr) |
MY (1) | MY161162A (fr) |
PE (1) | PE20140216A1 (fr) |
PL (1) | PL2661261T3 (fr) |
PT (1) | PT2661261T (fr) |
SG (1) | SG191286A1 (fr) |
SI (1) | SI2661261T1 (fr) |
TN (1) | TN2013000257A1 (fr) |
TW (2) | TWI610672B (fr) |
UA (1) | UA114283C2 (fr) |
WO (1) | WO2012093161A1 (fr) |
ZA (1) | ZA201304465B (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX357304B (es) | 2011-01-07 | 2018-07-04 | Novartis Ag | Formulaciones inmunosupresoras. |
PT3129006T (pt) * | 2014-04-10 | 2021-04-09 | Novartis Ag | Formulação imunossupressora |
MX2016013245A (es) * | 2014-04-10 | 2017-01-16 | Novartis Ag | Regimen de dosificacion de liberacion inmediata de moduladores s1p. |
CA2973540A1 (fr) | 2015-02-26 | 2016-09-01 | Novartis Ag | Traitement de maladie auto-immune chez un patient recevant en outre un betabloquant |
PL3318259T3 (pl) | 2015-07-03 | 2023-05-02 | Astellas Pharma Inc. | Stabilna kompozycja farmaceutyczna do podawania doustnego |
US11629124B2 (en) | 2017-03-09 | 2023-04-18 | Novartis Ag | Solid forms comprising an oxime ether compound, compositions and methods of use thereof |
US11434200B2 (en) | 2017-03-09 | 2022-09-06 | Novartis Ag | Solid forms comprising an oxime ether compound and a coformer, compositions and methods of use thereof |
KR20200059221A (ko) | 2017-09-27 | 2020-05-28 | 노파르티스 아게 | 시포니모드를 포함하는 비경구 제형 |
WO2019064217A1 (fr) | 2017-09-29 | 2019-04-04 | Novartis Ag | Schéma posologique de siponimod |
KR20200062241A (ko) | 2017-09-29 | 2020-06-03 | 노파르티스 아게 | 시포니모드의 투여 요법 |
CN109908095A (zh) * | 2019-04-08 | 2019-06-21 | 肇庆学院 | 一种西尼莫德片剂及制备方法 |
WO2021214717A1 (fr) | 2020-04-23 | 2021-10-28 | Novartis Ag | Schéma posologique pour l'utilisation de siponimod pour le traitement du syndrome de détresse respiratoire aiguë |
WO2023172508A1 (fr) * | 2022-03-09 | 2023-09-14 | Isp Investments Llc | Composition d'excipient co-traitée |
WO2024126409A1 (fr) | 2022-12-12 | 2024-06-20 | Synthon B.V. | Composition pharmaceutique contenant du siponimod |
Family Cites Families (44)
Publication number | Priority date | Publication date | Assignee | Title |
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US3872113A (en) | 1972-05-30 | 1975-03-18 | Endo Lab | Hydroxy- and acetoxy-phthalaldehydric acid, O-(substituted) oximes |
ES2126658T3 (es) | 1992-10-21 | 1999-04-01 | Yoshitomi Pharmaceutical | Compuesto de 2-amino-1,3-propanodiol e inmunosupresor. |
HU225964B1 (en) | 1994-07-12 | 2008-01-28 | Berwind Pharma Service | Moisture barrier film coating composition, method, and coated form |
CZ285953B6 (cs) | 1995-12-28 | 1999-12-15 | Yoshitomi Pharmaceutical Industries, Ltd. | Vnější přípravek pro topické podání |
MY121470A (en) | 1999-05-03 | 2006-01-28 | Ranbaxy Lab Ltd | Stable solid pharmaceutical compositions containing enalapril maleate |
JP2004507552A (ja) | 2000-08-31 | 2004-03-11 | メルク エンド カムパニー インコーポレーテッド | 免疫調節剤としてのリン酸誘導体 |
TW200800167A (en) | 2002-03-15 | 2008-01-01 | Novartis Ag | Organic compounds |
DK1505959T3 (da) | 2002-05-16 | 2009-02-23 | Novartis Ag | Anvendelse af EDG-receptorbindingsmidler ved cancer |
DK1566166T3 (da) * | 2002-11-07 | 2013-03-04 | Nippon Zettoc Co Ltd | Base til oral sammensætning og oral sammensætning |
PL1613288T3 (pl) | 2003-04-08 | 2009-07-31 | Novartis Ag | Stała kompozycja farmaceutyczna zawierająca agonistę receptora S1P oraz alkohol cukrowy |
MY150088A (en) | 2003-05-19 | 2013-11-29 | Irm Llc | Immunosuppressant compounds and compositions |
CA2524048C (fr) | 2003-05-19 | 2013-06-25 | Irm Llc | Composes immunosuppresseurs et compositions |
WO2004113330A1 (fr) | 2003-05-19 | 2004-12-29 | Irm Llc | Compositions et composes immunosuppresseurs |
EP1663188B1 (fr) | 2003-09-12 | 2016-08-10 | Newron Sweden AB | Traitement de maladies ou de lesions du systeme nerveux avec le fty720 |
WO2005044262A1 (fr) | 2003-10-29 | 2005-05-19 | Wyeth | Compositions pharmaceutiques a liberation lente contenant de l'aplindore et ses derives |
CA2563569A1 (fr) | 2004-05-03 | 2005-11-10 | Novartis Ag | Combinaisons comprenant un agoniste du recepteur s1p et un inhibiteur de la kinase jak3 |
US20060002999A1 (en) | 2004-06-17 | 2006-01-05 | Forest Laboratories, Inc. | Immediate release formulations of 1-aminocyclohexane compounds, memantine and neramexane |
AU2005309378B2 (en) | 2004-11-29 | 2010-02-11 | Novartis Ag | Dosage regimen of an S1P receptor agonist |
EP1688141A1 (fr) | 2005-01-31 | 2006-08-09 | elbion AG | Utilisation de flupirtine pour le traitement de la vessie hyperactive et des maladies associées et pour le traitement du syndrome du colon irritable |
GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
RU2296999C2 (ru) | 2005-03-09 | 2007-04-10 | Алексей Арнольдович Корженевский | Способ выявления критериев для проведения адекватной иммунотерапии гнойно-септических заболеваний |
GT200600350A (es) | 2005-08-09 | 2007-03-28 | Formulaciones líquidas | |
JP5269595B2 (ja) | 2005-09-09 | 2013-08-21 | アンジェリーニ ラボファーム リミテッド ライアビリティ カンパニー | 1日1回投与用トラゾドン組成物 |
GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
WO2008072056A1 (fr) | 2006-12-14 | 2008-06-19 | Pfizer Limited | Utilisation d'inhibiteurs de mtp pour traiter l'obésité au moyen de faibles doses et de doses augmentées |
DE102007019417A1 (de) | 2007-04-23 | 2008-11-13 | Grünenthal GmbH | Tapentadol zur Schmerzbehandlung bei Arthrose |
CA2684953C (fr) | 2007-05-04 | 2016-08-09 | Novartis Ag | Utilisation d'un modulateur des recepteurs s1p |
HUE027696T2 (en) * | 2007-10-12 | 2016-10-28 | Novartis Ag | Preparations containing sphingosine-1-phosphate (S1P) receptor modulators |
MY177360A (en) | 2008-03-17 | 2020-09-14 | Actelion Pharmaceuticals Ltd | Dosing regimen for aselective s1p1 receptor agonist |
KR20160131126A (ko) | 2008-06-20 | 2016-11-15 | 노파르티스 아게 | 다발성 경화증을 치료하기 위한 소아용 조성물 |
EP2695615A3 (fr) | 2008-07-23 | 2014-04-30 | Novartis AG | Modulateurs du récepteur de sphingosine 1 phosphate et leur utilisation pour le traitement de l'inflammation musculaire |
SG193803A1 (en) * | 2008-08-18 | 2013-10-30 | Novartis Ag | Compounds for the treatment of peripheral neuropathies |
JP2012512885A (ja) * | 2008-12-18 | 2012-06-07 | ノバルティス アーゲー | 新規な塩 |
AU2009335924B2 (en) | 2008-12-18 | 2012-11-08 | Novartis Ag | Hemifumarate salt of 1- [4- [1- ( 4 -cyclohexyl-3 -trifluoromethyl-benzyloxyimino ) -ethyl] -2 -ethyl-benzyl] -a zetidine-3-carboxylic acid |
EP2379498B1 (fr) * | 2008-12-18 | 2015-01-21 | Novartis AG | Forme polymorphe de l' acide 1-(4-{1-[(e)-4-cyclohexyl-3-trifluorométhyl-benzyloxyimino]-éthyl}-2-éthyl-benzyl)-azétidine-3-carboxylique |
US20110247617A1 (en) | 2008-12-19 | 2011-10-13 | Thomas Nilsson | Mouthpiece for an inhaler |
RS59857B1 (sr) | 2008-12-22 | 2020-02-28 | Novartis Ag | Režim doziranja agonista s1p receptora |
IL294658A (en) | 2008-12-22 | 2022-09-01 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
US20120264719A1 (en) | 2009-09-29 | 2012-10-18 | Craig Boulton | Dosage regimen of an s1p receptor modulator |
MX357304B (es) | 2011-01-07 | 2018-07-04 | Novartis Ag | Formulaciones inmunosupresoras. |
WO2012095853A1 (fr) | 2011-01-10 | 2012-07-19 | Novartis Pharma Ag | Formulations à libération modifiée comprenant des modulateurs des récepteurs sip |
TW201320994A (zh) | 2011-10-11 | 2013-06-01 | Novartis Ag | 投藥療程 |
MX2015014014A (es) | 2013-04-04 | 2016-02-10 | Novartis Ag | Identificacion de la respuesta del paciente a la administracion de un modulador del receptor s1p. |
PT3129006T (pt) | 2014-04-10 | 2021-04-09 | Novartis Ag | Formulação imunossupressora |
-
2012
- 2012-01-05 MX MX2013007909A patent/MX357304B/es active IP Right Grant
- 2012-01-05 UA UAA201307576A patent/UA114283C2/uk unknown
- 2012-01-05 WO PCT/EP2012/050151 patent/WO2012093161A1/fr active Application Filing
- 2012-01-05 MX MX2017007300A patent/MX371290B/es unknown
- 2012-01-05 BR BR112013017302-5A patent/BR112013017302B1/pt active IP Right Grant
- 2012-01-05 ES ES12700262T patent/ES2751920T3/es active Active
- 2012-01-05 JO JOP/2012/0005A patent/JO3619B1/ar active
- 2012-01-05 SG SG2013047923A patent/SG191286A1/en unknown
- 2012-01-05 EA EA201391018A patent/EA026144B9/ru active Protection Beyond IP Right Term
- 2012-01-05 LT LT12700262T patent/LT2661261T/lt unknown
- 2012-01-05 DK DK12700262.4T patent/DK2661261T3/da active
- 2012-01-05 PL PL12700262T patent/PL2661261T3/pl unknown
- 2012-01-05 EP EP12700262.4A patent/EP2661261B1/fr active Active
- 2012-01-05 CN CN201280004869.2A patent/CN103458877B/zh active Active
- 2012-01-05 SI SI201231683T patent/SI2661261T1/sl unknown
- 2012-01-05 EP EP19188018.6A patent/EP3590507A1/fr active Pending
- 2012-01-05 JP JP2013547861A patent/JP6111202B2/ja active Active
- 2012-01-05 AU AU2012204835A patent/AU2012204835B2/en active Active
- 2012-01-05 PE PE2013001522A patent/PE20140216A1/es active IP Right Grant
- 2012-01-05 CA CA2823616A patent/CA2823616C/fr active Active
- 2012-01-05 KR KR1020197004860A patent/KR102166885B1/ko active IP Right Grant
- 2012-01-05 PT PT127002624T patent/PT2661261T/pt unknown
- 2012-01-05 KR KR1020137020755A patent/KR101951966B1/ko active IP Right Grant
- 2012-01-05 MA MA36170A patent/MA34897B1/fr unknown
- 2012-01-05 HU HUE12700262A patent/HUE045612T2/hu unknown
- 2012-01-06 MY MYPI2013002251A patent/MY161162A/en unknown
- 2012-01-06 TW TW101100702A patent/TWI610672B/zh active
- 2012-01-06 TW TW104142389A patent/TWI583380B/zh active
- 2012-01-06 AR ARP120100047A patent/AR084801A1/es not_active Application Discontinuation
-
2013
- 2013-06-14 US US13/917,730 patent/US20130273161A1/en not_active Abandoned
- 2013-06-14 TN TNP2013000257A patent/TN2013000257A1/fr unknown
- 2013-06-18 ZA ZA2013/04465A patent/ZA201304465B/en unknown
- 2013-06-20 IL IL227094A patent/IL227094B/en active IP Right Grant
- 2013-07-05 GT GT201300178A patent/GT201300178A/es unknown
- 2013-07-05 CL CL2013001979A patent/CL2013001979A1/es unknown
- 2013-07-16 CO CO13168667A patent/CO6761402A2/es unknown
- 2013-08-07 EC ECSP13012812 patent/ECSP13012812A/es unknown
-
2017
- 2017-03-13 JP JP2017047220A patent/JP6324569B2/ja active Active
-
2019
- 2019-10-11 HR HRP20191842TT patent/HRP20191842T1/hr unknown
- 2019-10-22 CY CY20191101097T patent/CY1122182T1/el unknown
-
2020
- 2020-02-28 US US16/804,926 patent/US20200199069A1/en not_active Abandoned
-
2021
- 2021-04-14 US US17/230,175 patent/US12071402B2/en active Active
-
2022
- 2022-01-17 AR ARP220100086A patent/AR124662A2/es unknown
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