MA30298B1 - Composition - Google Patents
CompositionInfo
- Publication number
- MA30298B1 MA30298B1 MA30238A MA30238A MA30298B1 MA 30298 B1 MA30298 B1 MA 30298B1 MA 30238 A MA30238 A MA 30238A MA 30238 A MA30238 A MA 30238A MA 30298 B1 MA30298 B1 MA 30298B1
- Authority
- MA
- Morocco
- Prior art keywords
- oil
- water emulsion
- vaccine formulations
- immunization
- mpl
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/11—Orthomyxoviridae, e.g. influenza virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La présente invention porte sur des formulations de vaccin antigrippal et des schémas posologiques de vaccination permettant l'immunisation contre diverses maladies. Cette invention concerne en particulier des formulations de vaccin renfermant un adjuvant d'émulsion huile-dans-eau et un 3D-MPL, leur utilisation en médecine, en particulier leur utilisation pour accroître les réponses immunitaires à divers antigènes, ainsi que des méthodes de préparation, laquelle émulsion huile-dans-eau comprend un stérol, une huile métabolisable et un agent émulsifiant.
Applications Claiming Priority (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0505998A GB0505998D0 (en) | 2005-03-23 | 2005-03-23 | Novel compositions |
GB0506000A GB0506000D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
GB0506001A GB0506001D0 (en) | 2005-03-23 | 2005-03-23 | Novel use |
GB0506004A GB0506004D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
GB0505989A GB0505989D0 (en) | 2005-03-23 | 2005-03-23 | Compositions |
GB0510589A GB0510589D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
GB0510593A GB0510593D0 (en) | 2005-05-24 | 2005-05-24 | Novel compositions |
GB0510591A GB0510591D0 (en) | 2005-05-24 | 2005-05-24 | Novel use |
GB0510596A GB0510596D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
GB0510598A GB0510598D0 (en) | 2005-05-24 | 2005-05-24 | Composition |
GB0603790A GB0603790D0 (en) | 2006-02-24 | 2006-02-24 | Composition |
GB0603788A GB0603788D0 (en) | 2006-02-24 | 2006-02-24 | Novel composition |
GB0603789A GB0603789D0 (en) | 2006-02-24 | 2006-02-24 | Novel use |
Publications (1)
Publication Number | Publication Date |
---|---|
MA30298B1 true MA30298B1 (fr) | 2009-04-01 |
Family
ID=36441219
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30241A MA29342B1 (fr) | 2005-03-23 | 2007-09-24 | Nouvelle composition |
MA30240A MA29715B1 (fr) | 2005-03-23 | 2007-09-24 | Utilisation d'un virus de la grippe et d'un adjuvant de type emulsion huile dans l'eau pour induire une cellule t cd-4 et/ou ameliorer la reponse de la cellule a memoire b |
MA30238A MA30298B1 (fr) | 2005-03-23 | 2007-09-24 | Composition |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA30241A MA29342B1 (fr) | 2005-03-23 | 2007-09-24 | Nouvelle composition |
MA30240A MA29715B1 (fr) | 2005-03-23 | 2007-09-24 | Utilisation d'un virus de la grippe et d'un adjuvant de type emulsion huile dans l'eau pour induire une cellule t cd-4 et/ou ameliorer la reponse de la cellule a memoire b |
Country Status (24)
Country | Link |
---|---|
US (5) | US20090081253A1 (fr) |
EP (4) | EP1861120B1 (fr) |
JP (4) | JP5770414B2 (fr) |
KR (5) | KR20070116650A (fr) |
AR (3) | AR053833A1 (fr) |
AU (3) | AU2006226459A1 (fr) |
CA (3) | CA2601022C (fr) |
CY (1) | CY1117874T1 (fr) |
DK (1) | DK1861120T3 (fr) |
EA (3) | EA011393B1 (fr) |
ES (1) | ES2585810T3 (fr) |
HR (1) | HRP20160816T1 (fr) |
HU (1) | HUE027837T2 (fr) |
IL (3) | IL185901A0 (fr) |
MA (3) | MA29342B1 (fr) |
MX (3) | MX2007011756A (fr) |
NO (3) | NO20074635L (fr) |
NZ (2) | NZ561823A (fr) |
PE (3) | PE20061428A1 (fr) |
PL (1) | PL1861120T3 (fr) |
PT (1) | PT1861120T (fr) |
SI (1) | SI1861120T1 (fr) |
TW (3) | TW200700079A (fr) |
WO (3) | WO2006100109A1 (fr) |
Families Citing this family (84)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2371994C (fr) * | 1999-02-26 | 2010-09-28 | Guido Grandi | Developpement de l'activite bactericide des antigenes de neisseria a l'aide d'oligonucleotides a motifs cg |
GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
US20100221284A1 (en) * | 2001-05-30 | 2010-09-02 | Saech-Sisches Serumwerk Dresden | Novel vaccine composition |
DE10144906B4 (de) | 2001-09-12 | 2013-11-28 | Novartis Vaccines And Diagnostics Gmbh | Verfahren zur großtechnischen Herstellung von Impfstoffen |
KR20070116650A (ko) * | 2005-03-23 | 2007-12-10 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 조성물 |
US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
DE202006021242U1 (de) * | 2005-11-04 | 2014-01-29 | Novartis Vaccines And Diagnostics S.R.L. | Emulsionen mit freiem wässrigen Phasen Tensid als Adjuvans für Spalt-Grippeimpfstoffe |
JP2009514838A (ja) * | 2005-11-04 | 2009-04-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 細胞培養物において増殖されたインフルエンザウイルスから調製された非ビリオン抗原を含むアジュバントワクチン |
ATE513561T1 (de) | 2005-11-04 | 2011-07-15 | Novartis Vaccines & Diagnostic | Veränderung des th1/th2-gleichgewichts in spalt- grippeimpfstoffen mit adjuvantien |
CN102755645A (zh) * | 2005-11-04 | 2012-10-31 | 诺华疫苗和诊断有限公司 | 佐剂配制的包含细胞因子诱导剂的流感疫苗 |
FR2896162B1 (fr) * | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
TW200745158A (en) | 2006-03-07 | 2007-12-16 | Vaxinnate Corp | Compositions that include hemagglutinin, methods of making and methods of use thereof |
CA2646349A1 (fr) * | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Stockage de vaccins antigrippaux sans refrigeration |
CN101500603A (zh) * | 2006-06-15 | 2009-08-05 | 诺华有限公司 | 节省佐剂的多剂量流感疫苗接种方案 |
WO2008009309A1 (fr) | 2006-07-17 | 2008-01-24 | Glaxosmithkline Biologicals S.A. | Vaccin anti-grippal |
CA2583555C (fr) * | 2006-07-17 | 2020-01-07 | Glaxosmithkline Biologicals S.A. | Vaccin contre la grippe |
SI2422810T1 (sl) * | 2006-07-17 | 2015-01-30 | Glaxosmithkline Biologicals S.A. | Influenčno cepivo |
ES2397714T3 (es) * | 2006-10-12 | 2013-03-08 | Glaxosmithkline Biologicals S.A. | Vacuna que comprende un adyuvante de emulsión de aceite en agua |
SI2086582T1 (sl) * | 2006-10-12 | 2013-02-28 | Glaxosmithkline Biologicals S.A. | Cepivo, ki obsega emulzijo olja v vodi kot adjuvans |
GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
EP1923070A1 (fr) * | 2006-11-15 | 2008-05-21 | Intervet International BV | Vaccin pour vacciner un félin contre le virus influenza |
SG177141A1 (en) * | 2006-12-06 | 2012-01-30 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
EP1938835A1 (fr) * | 2006-12-29 | 2008-07-02 | Pevion Biotech AG | Agent immunostimulant non spécifique |
AU2008231242B2 (en) * | 2007-02-23 | 2013-01-31 | Baylor Research Institute | Therapeutic applications of activation of human antigen-presenting cells through Dectin-1 |
PE20090146A1 (es) * | 2007-04-20 | 2009-03-23 | Glaxosmithkline Biolog Sa | Composicion inmunogenica contra el virus influenza |
EP2195019A4 (fr) * | 2007-10-12 | 2012-02-15 | Csl Ltd | Procédé d'élicitation d'une réponse immunitaire dirigée contre le virus de l'influenza pandémique |
SI2200642T1 (sl) * | 2007-10-19 | 2012-06-29 | Novartis Ag | Formulacije meningokoknega cepiva |
GB0810305D0 (en) † | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
EP2227251A1 (fr) | 2007-12-06 | 2010-09-15 | GlaxoSmithKline Biologicals SA | Composition contre la grippe |
US8466259B2 (en) * | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
US8426163B2 (en) * | 2007-12-07 | 2013-04-23 | National Health Research Institutes | Production of lipidated proteins in E. coli |
CN101998990B (zh) * | 2008-03-18 | 2013-11-27 | 诺华股份有限公司 | 流感病毒疫苗抗原制备方法的改进 |
WO2009128949A2 (fr) | 2008-04-18 | 2009-10-22 | Vaxinnate Corporation | Compositions de proteines du virus de la dengue et methodes d’utilisation associees |
GB0905570D0 (en) * | 2009-03-31 | 2009-05-13 | Novartis Ag | Combined vaccines |
US9421251B2 (en) | 2008-06-25 | 2016-08-23 | Novartis Ag | Rapid responses to delayed booster immunisations |
JP5642712B2 (ja) | 2009-02-10 | 2014-12-17 | ノバルティス アーゲー | 少ない量のスクアレンを含むインフルエンザワクチン |
EA201171032A1 (ru) | 2009-02-10 | 2012-02-28 | Новартис Аг | Схемы лечения с помощью вакцины против гриппа, связанного с пандемическими штаммами |
AU2015203072B2 (en) * | 2009-02-10 | 2017-05-25 | Seqirus UK Limited | Influenza vaccine regimens for pandemic-associated strains |
US8287880B2 (en) * | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
EP2445927B1 (fr) * | 2009-06-22 | 2014-04-23 | National Health Research Institutes | Antigenes lipides associes aux tumeurs et compositions immunotherapeutiques |
EP2289575B1 (fr) * | 2009-08-06 | 2017-07-05 | Biotronik VI Patent AG | Implant médical contenant une substance anti-oxydante |
IN2012DN00781A (fr) * | 2009-08-12 | 2015-06-26 | Sigmoid Pharma Ltd | |
EP2308506A1 (fr) * | 2009-10-02 | 2011-04-13 | Mucosis B.V. | Formulations de vaccin intranasal avec adjuvants |
GB0918830D0 (en) | 2009-10-27 | 2009-12-09 | Glaxosmithkline Biolog Niederl | Process |
GB0919117D0 (en) | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
DE102009056871A1 (de) | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
AU2013202690B2 (en) * | 2009-12-03 | 2016-02-11 | Novartis Ag | Hydrophilic filtration during manufacture of vaccine adjuvants |
CA2782511C (fr) | 2009-12-03 | 2013-11-12 | Novartis Ag | Circulation de constituants lors de l'homogeneisation d'emulsions |
CL2012001399A1 (es) | 2009-12-03 | 2013-03-08 | Novartis Ag | Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion. |
CN102740832B (zh) * | 2009-12-03 | 2016-01-13 | 诺华股份有限公司 | 就微流化排列交互作用和背压室 |
DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
EA025622B1 (ru) * | 2009-12-03 | 2017-01-30 | Новартис Аг | Способ получения содержащей сквален эмульсии масла |
DE102009056884B4 (de) | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
JP5894083B2 (ja) * | 2009-12-22 | 2016-03-23 | サノフィ パストゥール リミテッドSanofi Pasteur Limited | 免疫原性組成物 |
SG182305A1 (en) * | 2010-01-06 | 2012-08-30 | Vaxinnate Corp | Methods and compositions for providing protective immunity in the elderly |
WO2011088451A1 (fr) * | 2010-01-15 | 2011-07-21 | Novavax, Inc. | Utilisations de particules de type virus de la grippe (vlps) pour la caractérisation de l'activité neuraminidase et hémagglutinine |
RU2527688C2 (ru) * | 2010-02-27 | 2014-09-10 | Общество С Ограниченной Ответственностью "Научно-Производственная Фирма "Материа Медика Холдинг" | Способ лечения инфекционных заболеваний, вызванных вирусом гриппа с типом поверхностого антигена н1n1 и лекарственное средство для лечения инфекционных заболеваний, вызванных вирусом гриппа с типом поверхностного антигена н1n1 |
GB201009671D0 (en) | 2010-06-10 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel process |
GB201009676D0 (en) | 2010-06-10 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel process |
GB201009673D0 (en) | 2010-06-10 | 2010-07-21 | Glaxosmithkline Biolog Sa | Novel process |
US9821051B1 (en) | 2010-10-28 | 2017-11-21 | Seqirus UK Limited | Reducing hospitalization in elderly influenza vaccine recipients |
TW201221642A (en) | 2010-11-15 | 2012-06-01 | Nat Health Research Institutes | Method of producing lipidated polypeptides |
TWI507413B (zh) | 2010-11-15 | 2015-11-11 | Nat Health Research Institutes | 脂質化多抗原表位疫苗 |
WO2012116714A1 (fr) | 2011-03-02 | 2012-09-07 | Curevac Gmbh | Vaccination chez des patients âgés |
US20160015800A1 (en) * | 2012-12-28 | 2016-01-21 | Japan As Represented By Director General Of National Institute Of Infectious Diseases | Nasal influenza vaccine composition |
JP2016521282A (ja) * | 2013-05-10 | 2016-07-21 | ノバルティス アーゲー | インフルエンザワクチンにおけるナルコレプシーのリスクの回避 |
US10080792B2 (en) * | 2013-09-23 | 2018-09-25 | Engen Bio, Inc. | Influenza vaccine and therapy |
CN104436157A (zh) * | 2013-09-23 | 2015-03-25 | 恩金生物有限公司 | 流感疫苗和治疗 |
US20170304429A1 (en) | 2014-09-26 | 2017-10-26 | Seqirus UK Limited | Vaccination of immunocompromised subjects |
WO2019108928A1 (fr) * | 2017-11-30 | 2019-06-06 | Ohio State Innovation Foundation | Système d'administration de vaccin contre le virus de la grippe piégé par des nanoparticules mucoadhésives |
CN113993542A (zh) * | 2019-01-30 | 2022-01-28 | 葛兰素史密丝克莱恩生物有限公司 | 用于自乳化的油/表面活性剂混合物 |
MX2022007691A (es) * | 2019-12-20 | 2022-07-19 | Fresenius Kabi Austria Gmbh | Metodo para producir emulsiones aceite en agua. |
RU2741003C1 (ru) * | 2020-03-27 | 2021-01-22 | Евгений Дмитриевич Некрасов | Способ производства четырехвалентной субъединичной вакцины против гриппа без адъювантов |
US20230256090A1 (en) | 2020-06-29 | 2023-08-17 | Glaxosmithkline Biologicals Sa | Adjuvants |
MX2023002339A (es) | 2020-08-24 | 2023-03-22 | Sanofi Pasteur Inc | Vacunas contra infecciones por sars-cov-2. |
CA3190375A1 (fr) | 2020-08-24 | 2022-03-03 | Natalie ANOSOVA | Vaccins contre la covid-19 avec des adjuvants d'emulsion de squalene contenant du tocopherol |
KR102270165B1 (ko) | 2020-10-22 | 2021-06-28 | 한국화학연구원 | 세정제 조성물 |
WO2022200582A1 (fr) | 2021-03-26 | 2022-09-29 | Glaxosmithkline Biologicals Sa | Compositions immunogènes |
WO2023274860A1 (fr) | 2021-06-28 | 2023-01-05 | Glaxosmithkline Biologicals Sa | Nouveaux antigènes de la grippe |
RU2766292C1 (ru) * | 2021-08-05 | 2022-03-14 | Федеральное государственное унитарное предприятие "Санкт-Петербургский научно-исследовательский институт вакцин и сывороток и предприятие по производству бактерийных препаратов" Федерального медико-биологического агентства (ФГУП СПбНИИВС ФМБА России) | Состав вакцины против covid-19 |
WO2023020992A1 (fr) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Nouveaux procédés |
WO2023020993A1 (fr) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Nouveaux procédés |
WO2023020994A1 (fr) | 2021-08-16 | 2023-02-23 | Glaxosmithkline Biologicals Sa | Nouveaux procédés |
WO2023061993A1 (fr) | 2021-10-13 | 2023-04-20 | Glaxosmithkline Biologicals Sa | Polypeptides |
Family Cites Families (116)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3095974A (en) * | 1961-10-27 | 1963-07-02 | Anthony R Perini | Collapsible book rack |
US4047869A (en) * | 1973-02-23 | 1977-09-13 | Mulvany Jr R F | Apparatus for forming plastic articles |
FR2333610A1 (fr) * | 1975-12-03 | 1977-07-01 | Zhdanovsky Z Tyazhelogo Mash | Bande-electrode a ame en poudre pour rechargement a l'aide d'un alliage resistant a l'usure |
US4270537A (en) | 1979-11-19 | 1981-06-02 | Romaine Richard A | Automatic hypodermic syringe |
DD155875A1 (de) | 1980-12-31 | 1982-07-14 | Willy Nordheim | Verfahren zur herstellung eines ballaststoffarmen inaktivierten influenzaimpfstoffes |
US4436727A (en) * | 1982-05-26 | 1984-03-13 | Ribi Immunochem Research, Inc. | Refined detoxified endotoxin product |
US4866034A (en) * | 1982-05-26 | 1989-09-12 | Ribi Immunochem Research Inc. | Refined detoxified endotoxin |
DD211444A3 (de) | 1982-08-19 | 1984-07-11 | Saechsisches Serumwerk | Verfahren zur herstellung von influenza-impfstoffen |
GB8300467D0 (en) | 1983-01-08 | 1983-02-09 | Wellcome Found | Equine influenza |
US4596556A (en) | 1985-03-25 | 1986-06-24 | Bioject, Inc. | Hypodermic injection apparatus |
DD300833A7 (de) | 1985-10-28 | 1992-08-13 | Saechsische Landesgewerbefoerd | Verfahren zur herstellung von inaktivierten influenza-vollvirusimpfstoffen |
CA1283827C (fr) | 1986-12-18 | 1991-05-07 | Giorgio Cirelli | Dispositif pour l'injection de formules liquides |
GB8704027D0 (en) | 1987-02-20 | 1987-03-25 | Owen Mumford Ltd | Syringe needle combination |
AU614755B2 (en) | 1987-06-05 | 1991-09-12 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Autocrine motility factors in cancer diagnosis and management |
US4940460A (en) | 1987-06-19 | 1990-07-10 | Bioject, Inc. | Patient-fillable and non-invasive hypodermic injection device assembly |
US4941880A (en) | 1987-06-19 | 1990-07-17 | Bioject, Inc. | Pre-filled ampule and non-invasive hypodermic injection device assembly |
US4790824A (en) | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
DE3734306A1 (de) | 1987-10-10 | 1989-04-27 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung fuer fliessfaehige medien |
US5376369A (en) * | 1987-11-03 | 1994-12-27 | Syntex (U.S.A.) Inc. | Vaccine adjuvant |
US5339163A (en) | 1988-03-16 | 1994-08-16 | Canon Kabushiki Kaisha | Automatic exposure control device using plural image plane detection areas |
US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
GB8821049D0 (en) | 1988-09-08 | 1988-10-05 | Health Lab Service Board | Method & composition for treatment & prevention of viral infections |
FR2638359A1 (fr) | 1988-11-03 | 1990-05-04 | Tino Dalto | Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau |
DK0382271T3 (da) * | 1989-02-04 | 1995-05-01 | Akzo Nobel Nv | Tocoler som adjuvanser i vacciner |
US5092235A (en) | 1989-05-24 | 1992-03-03 | Tektronix, Inc. | Pressure fixing and developing apparatus |
HU212924B (en) | 1989-05-25 | 1996-12-30 | Chiron Corp | Adjuvant formulation comprising a submicron oil droplet emulsion |
US5064413A (en) | 1989-11-09 | 1991-11-12 | Bioject, Inc. | Needleless hypodermic injection device |
US5312335A (en) | 1989-11-09 | 1994-05-17 | Bioject Inc. | Needleless hypodermic injection device |
DE4005528C2 (de) | 1990-02-22 | 1998-01-15 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
US5969109A (en) * | 1990-02-28 | 1999-10-19 | Bona; Constantin | Chimeric antibodies comprising antigen binding sites and B and T cell epitopes |
WO1991013261A1 (fr) | 1990-03-02 | 1991-09-05 | Experimentalny Nauchno-Issledovatelsky Institut Metallorezhuschikh Stankov | Systeme numerique d'entrainement asservi |
US5149531A (en) * | 1990-06-27 | 1992-09-22 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Method of using cold-adapted live influenza virus vaccine as an antiviral agent against influenza |
US5190521A (en) | 1990-08-22 | 1993-03-02 | Tecnol Medical Products, Inc. | Apparatus and method for raising a skin wheal and anesthetizing skin |
US5527288A (en) | 1990-12-13 | 1996-06-18 | Elan Medical Technologies Limited | Intradermal drug delivery device and method for intradermal delivery of drugs |
GB9105992D0 (en) | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
GB9118204D0 (en) | 1991-08-23 | 1991-10-09 | Weston Terence E | Needle-less injector |
SE9102652D0 (sv) | 1991-09-13 | 1991-09-13 | Kabi Pharmacia Ab | Injection needle arrangement |
US5328483A (en) | 1992-02-27 | 1994-07-12 | Jacoby Richard M | Intradermal injection device with medication and needle guard |
MY111880A (en) | 1992-03-27 | 2001-02-28 | Smithkline Beecham Biologicals S A | Hepatitis vaccines containing 3-0 deacylated monophosphoryl lipid a |
US5383851A (en) | 1992-07-24 | 1995-01-24 | Bioject Inc. | Needleless hypodermic injection device |
US5569189A (en) | 1992-09-28 | 1996-10-29 | Equidyne Systems, Inc. | hypodermic jet injector |
US5334144A (en) | 1992-10-30 | 1994-08-02 | Becton, Dickinson And Company | Single use disposable needleless injector |
WO1994019013A1 (fr) | 1993-02-19 | 1994-09-01 | Smithkline Beecham Corporation | Compositions de vaccin contre la grippe, contenant un lipide a de monophosphoryle desacyle en position 3-o |
JPH08506592A (ja) * | 1993-02-19 | 1996-07-16 | スミスクライン・ビーチャム・コーポレイション | 3−o−脱アシル化モノホスホリル脂質A含有のインフルエンザワクチン組成物 |
CN1087176C (zh) | 1993-03-23 | 2002-07-10 | 史密斯克莱·比奇曼生物公司 | 含有3-o脱酰基单磷酰脂a的疫苗制剂 |
US5762939A (en) * | 1993-09-13 | 1998-06-09 | Mg-Pmc, Llc | Method for producing influenza hemagglutinin multivalent vaccines using baculovirus |
WO1995011700A1 (fr) | 1993-10-29 | 1995-05-04 | Pharmos Corp. | Emulsions submicroniques utilisees comme adjuvants de vaccin |
WO1995014026A1 (fr) | 1993-11-17 | 1995-05-26 | Laboratoires Om S.A. | Disaccharides de glucosamine, leur procede de preparation, composition pharmaceutique les contenant, et leurs utilisations |
GB9326253D0 (en) * | 1993-12-23 | 1994-02-23 | Smithkline Beecham Biolog | Vaccines |
BR9506885A (pt) | 1994-02-24 | 1997-08-19 | Micro Pak Inc | Vacinas contendo vesículas de lipidio paucilamelares como adjuvantes imunológicos |
WO1995024176A1 (fr) | 1994-03-07 | 1995-09-14 | Bioject, Inc. | Dispositif de remplissage d'ampoule |
US5466220A (en) | 1994-03-08 | 1995-11-14 | Bioject, Inc. | Drug vial mixing and transfer device |
WO1995026204A1 (fr) | 1994-03-25 | 1995-10-05 | Isis Pharmaceuticals, Inc. | Stimulation immunitaire par des analogues d'oligonucleotides de phosphorothioate |
US5599302A (en) | 1995-01-09 | 1997-02-04 | Medi-Ject Corporation | Medical injection system and method, gas spring thereof and launching device using gas spring |
UA56132C2 (uk) | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
US5893397A (en) | 1996-01-12 | 1999-04-13 | Bioject Inc. | Medication vial/syringe liquid-transfer apparatus |
GB9607549D0 (en) | 1996-04-11 | 1996-06-12 | Weston Medical Ltd | Spring-powered dispensing device |
US5916879A (en) | 1996-11-12 | 1999-06-29 | St. Jude Children's Research Hospital | DNA transcription unit vaccines that protect against avian influenza viruses and methods of use thereof |
TW570803B (en) | 1997-04-09 | 2004-01-11 | Duphar Int Res | Influenza vaccine |
US5993412A (en) | 1997-05-19 | 1999-11-30 | Bioject, Inc. | Injection apparatus |
GB9711990D0 (en) | 1997-06-11 | 1997-08-06 | Smithkline Beecham Biolog | Vaccine |
ES2298316T3 (es) * | 1997-09-05 | 2008-05-16 | Glaxosmithkline Biologicals S.A. | Emulsiones de aceite en agua que contienen saponinas. |
GB9718901D0 (en) | 1997-09-05 | 1997-11-12 | Smithkline Beecham Biolog | Vaccine |
IT1298087B1 (it) | 1998-01-08 | 1999-12-20 | Fiderm S R L | Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni |
PL343429A1 (en) * | 1998-03-09 | 2001-08-13 | Smithkline Beecham Biolog | Combined vaccine compositions |
US6838269B1 (en) * | 1998-04-15 | 2005-01-04 | Genencor International, Inc. | Proteins producing an altered immunogenic response and methods of making and using the same |
JP2002513773A (ja) | 1998-05-07 | 2002-05-14 | コリクサ コーポレイション | アジュバント組成物及びその使用法 |
SK18602000A3 (sk) | 1998-06-08 | 2001-07-10 | Sca Emballage France | Obal umožňujúci rýchle vyrovnanie |
HUP0102475A3 (en) | 1998-06-30 | 2001-12-28 | Om Pharma | Novel acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same |
AT408615B (de) | 1998-09-15 | 2002-01-25 | Immuno Ag | Neue influenzavirus-impfstoffzusammensetzung |
US20040006242A1 (en) | 1999-02-01 | 2004-01-08 | Hawkins Lynn D. | Immunomodulatory compounds and method of use thereof |
US6551600B2 (en) | 1999-02-01 | 2003-04-22 | Eisai Co., Ltd. | Immunological adjuvant compounds compositions and methods of use thereof |
AT407958B (de) | 1999-02-11 | 2001-07-25 | Immuno Ag | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
AU2875700A (en) | 1999-02-26 | 2000-09-14 | Chiron Corporation | Microemulsions with adsorbed macromoelecules and microparticles |
FR2796290B1 (fr) | 1999-07-16 | 2001-09-14 | Cross Site Technologies | Seringue sans aiguille fonctionnant avec un generateur d'onde de choc a travers une paroi |
FR2796291B1 (fr) | 1999-07-16 | 2001-09-21 | Cross Site Technologies | Seringue sans aiguille munie d'un systeme de declenchement piezo-electrique |
FR2796289B1 (fr) | 1999-07-16 | 2001-08-10 | Cross Site Technologies | Seringue sans aiguille avec injecteur a elements superposes |
GB9921146D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
GB9921147D0 (en) * | 1999-09-07 | 1999-11-10 | Smithkline Beecham Biolog | Novel composition |
GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
US6494865B1 (en) | 1999-10-14 | 2002-12-17 | Becton Dickinson And Company | Intradermal delivery device including a needle assembly |
FR2800619B1 (fr) | 1999-11-05 | 2002-02-08 | Cross Site Technologies | Seringue sans aiguille avec un moyen de poussee temporairement retenu |
FR2802102B1 (fr) | 1999-12-08 | 2002-07-12 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un tube d'ejection a section constante |
FR2802103B1 (fr) | 1999-12-08 | 2003-10-03 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant avec entrainement du principe actif par effet tube a choc |
AU1581400A (en) | 1999-12-22 | 2001-07-03 | Om Pharma | Acyl pseudopeptides bearing a functionalised auxiliary spacer |
FR2802820B1 (fr) | 1999-12-27 | 2002-10-18 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant par effet tube a choc, avec maintien prealable du principe actif sur le cote |
CZ20022643A3 (cs) | 2000-01-31 | 2003-02-12 | Smithkline Beecham Biologicals S. A. | Farmaceutický prostředek |
FR2804329B1 (fr) | 2000-02-02 | 2002-12-13 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un opercule contenant le principe actif |
FR2804869B1 (fr) | 2000-02-11 | 2002-05-17 | Poudres & Explosifs Ste Nale | Seringue sans aiguille pour l'injection d'un liquide contenu dans une ampoule pre-remplie |
FR2805749B1 (fr) | 2000-03-01 | 2002-05-17 | Poudres & Explosifs Ste Nale | Seringue sans aiguille a deux niveaux de vitesse d'injection |
FR2807946B1 (fr) | 2000-04-19 | 2002-06-07 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant avec un chargement pyrotechnique bicomposition |
FR2809626B1 (fr) | 2000-05-30 | 2003-03-07 | Poudres & Explosifs Ste Nale | Seringue sans aiguille avec membrane d'isolation d'un ejecteur multiconduit |
FR2810554B1 (fr) | 2000-06-22 | 2003-05-16 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un reservoir modulable |
FR2812202B1 (fr) | 2000-07-28 | 2002-09-13 | Poudres & Explosifs Ste Nale | Seringue sans aiguille fonctionnant par mise en compression du reservoir contenant le principe actif liquide |
GB0025577D0 (en) * | 2000-10-18 | 2000-12-06 | Smithkline Beecham Biolog | Vaccine |
FR2815544B1 (fr) | 2000-10-23 | 2003-02-14 | Poudres & Explosifs Ste Nale | Seringue sans aiguille securisee a architecture compacte |
EP1201250A1 (fr) | 2000-10-25 | 2002-05-02 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Composition immunogène contenant des antigènes de plasmodium spécifiques des stades hépatiques |
PT1361890E (pt) | 2001-02-23 | 2011-06-07 | Glaxosmithkline Biolog Sa | Formulações vacinais de influenza para distribuição intradérmica |
MY134424A (en) * | 2001-05-30 | 2007-12-31 | Saechsisches Serumwerk | Stable influenza virus preparations with low or no amount of thiomersal |
US7361352B2 (en) * | 2001-08-15 | 2008-04-22 | Acambis, Inc. | Influenza immunogen and vaccine |
US6861410B1 (en) | 2002-03-21 | 2005-03-01 | Chiron Corporation | Immunological adjuvant compositions |
CA2478930A1 (fr) * | 2002-04-01 | 2003-10-16 | Euro-Celtique, S.A. | Produits de recombinaison d'epitope comprenant des mecanismes de ciblage de cellules presentant un antigene |
EP1594536B1 (fr) | 2003-01-30 | 2009-03-25 | Novartis Vaccines and Diagnostics, Inc. | Vaccin contre la grippe contenant un adjuvant |
WO2005107797A1 (fr) * | 2004-03-09 | 2005-11-17 | Chiron Corporation | Vaccins antigrippaux |
KR20070116650A (ko) * | 2005-03-23 | 2007-12-10 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 조성물 |
US20090028903A1 (en) * | 2005-03-23 | 2009-01-29 | Glaxosmithkline Biologicals, S.A. | Novel use |
AR054822A1 (es) | 2005-07-07 | 2007-07-18 | Sanofi Pasteur | Emulsion inmuno adyuvante |
AU2006310163B2 (en) | 2005-11-04 | 2011-09-15 | Seqirus UK Limited | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
FR2896162B1 (fr) | 2006-01-13 | 2008-02-15 | Sanofi Pasteur Sa | Emulsion huile dans eau thermoreversible |
US9101578B2 (en) | 2006-05-01 | 2015-08-11 | Technovax, Inc. | Polyvalent influenza virus-like particle (VLP) compositions |
SI2422810T1 (sl) * | 2006-07-17 | 2015-01-30 | Glaxosmithkline Biologicals S.A. | Influenčno cepivo |
WO2008009309A1 (fr) | 2006-07-17 | 2008-01-24 | Glaxosmithkline Biologicals S.A. | Vaccin anti-grippal |
ES2397714T3 (es) * | 2006-10-12 | 2013-03-08 | Glaxosmithkline Biologicals S.A. | Vacuna que comprende un adyuvante de emulsión de aceite en agua |
PE20090146A1 (es) * | 2007-04-20 | 2009-03-23 | Glaxosmithkline Biolog Sa | Composicion inmunogenica contra el virus influenza |
EP2227251A1 (fr) * | 2007-12-06 | 2010-09-15 | GlaxoSmithKline Biologicals SA | Composition contre la grippe |
-
2006
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- 2006-03-21 DK DK06723805.5T patent/DK1861120T3/en active
- 2006-03-21 AR ARP060101107A patent/AR054020A1/es not_active Application Discontinuation
- 2006-03-21 US US11/909,414 patent/US20090081253A1/en not_active Abandoned
- 2006-03-21 PE PE2006000311A patent/PE20061300A1/es not_active Application Discontinuation
- 2006-03-21 US US11/909,388 patent/US20080171063A1/en not_active Abandoned
- 2006-03-21 HU HUE06723805A patent/HUE027837T2/en unknown
- 2006-03-21 PL PL06723805.5T patent/PL1861120T3/pl unknown
- 2006-03-21 MX MX2007011748A patent/MX2007011748A/es not_active Application Discontinuation
- 2006-03-21 JP JP2008502344A patent/JP5869744B2/ja active Active
- 2006-03-21 AU AU2006226543A patent/AU2006226543B2/en active Active
- 2006-03-21 PT PT67238055T patent/PT1861120T/pt unknown
- 2006-03-21 KR KR1020077024383A patent/KR20070116651A/ko not_active Application Discontinuation
- 2006-03-21 NZ NZ561822A patent/NZ561822A/en not_active IP Right Cessation
- 2006-03-21 AR ARP060101108A patent/AR052625A1/es unknown
- 2006-03-21 EP EP06723807A patent/EP1861122A1/fr not_active Withdrawn
- 2006-03-21 EP EP11173265A patent/EP2397153A1/fr not_active Withdrawn
- 2006-03-21 EA EA200701787A patent/EA200701787A1/ru unknown
- 2006-03-21 US US11/909,351 patent/US20080181911A1/en not_active Abandoned
- 2006-03-21 CA CA002602456A patent/CA2602456A1/fr not_active Abandoned
- 2006-03-23 PE PE2006000334A patent/PE20061387A1/es not_active Application Discontinuation
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2007
- 2007-09-11 IL IL185901A patent/IL185901A0/en unknown
- 2007-09-11 IL IL185897A patent/IL185897A/en active IP Right Grant
- 2007-09-11 IL IL185906A patent/IL185906A0/en unknown
- 2007-09-12 NO NO20074635A patent/NO20074635L/no not_active Application Discontinuation
- 2007-09-12 NO NO20074638A patent/NO20074638L/no not_active Application Discontinuation
- 2007-09-24 MA MA30241A patent/MA29342B1/fr unknown
- 2007-09-24 MA MA30240A patent/MA29715B1/fr unknown
- 2007-09-24 MA MA30238A patent/MA30298B1/fr unknown
- 2007-09-28 NO NO20074930A patent/NO20074930L/no not_active Application Discontinuation
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2011
- 2011-04-28 US US13/096,180 patent/US20110287054A1/en not_active Abandoned
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2014
- 2014-01-31 JP JP2014016254A patent/JP2014129359A/ja active Pending
- 2014-08-21 US US14/465,055 patent/US9730999B2/en active Active
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2016
- 2016-07-07 HR HRP20160816TT patent/HRP20160816T1/hr unknown
- 2016-08-05 CY CY20161100772T patent/CY1117874T1/el unknown
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