MA29601B1 - Vaccin antipaludeen - Google Patents

Vaccin antipaludeen

Info

Publication number
MA29601B1
MA29601B1 MA30510A MA30510A MA29601B1 MA 29601 B1 MA29601 B1 MA 29601B1 MA 30510 A MA30510 A MA 30510A MA 30510 A MA30510 A MA 30510A MA 29601 B1 MA29601 B1 MA 29601B1
Authority
MA
Morocco
Prior art keywords
antipaludeen
vaccine
derivative
travelers
saponin
Prior art date
Application number
MA30510A
Other languages
English (en)
Inventor
Joseph D Cohen
Original Assignee
Glaxosmithkline Biolog Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34856445&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA29601(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa
Publication of MA29601B1 publication Critical patent/MA29601B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/68—Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6075—Viral proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne, entre autres, un procédé destiné à la prophylaxie de l'infection par le paludisme chez les voyageurs qui se rendent dans des régions endémiques, comprenant l'administration de quantités adéquates d'une formulation contenant un antigène de Plasmodium ou un fragment immunogénique ou un dérivé de celui-ci et un adjuvant, comprenant un dérivé de lipide A et une saponine dans une formulation liposomique.
MA30510A 2005-06-30 2007-12-26 Vaccin antipaludeen MA29601B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0513421.8A GB0513421D0 (en) 2005-06-30 2005-06-30 Vaccines

Publications (1)

Publication Number Publication Date
MA29601B1 true MA29601B1 (fr) 2008-07-01

Family

ID=34856445

Family Applications (1)

Application Number Title Priority Date Filing Date
MA30510A MA29601B1 (fr) 2005-06-30 2007-12-26 Vaccin antipaludeen

Country Status (22)

Country Link
US (1) US9279006B2 (fr)
EP (1) EP1896060B1 (fr)
JP (1) JP5486802B2 (fr)
KR (2) KR20130111648A (fr)
CN (1) CN101208100A (fr)
AR (1) AR055069A1 (fr)
AU (1) AU2006265329B2 (fr)
BR (1) BRPI0613087A2 (fr)
CA (1) CA2613057C (fr)
EA (1) EA200702633A1 (fr)
ES (1) ES2529577T3 (fr)
GB (1) GB0513421D0 (fr)
IL (1) IL187769A0 (fr)
MA (1) MA29601B1 (fr)
MX (1) MX2007016240A (fr)
NO (1) NO20076200L (fr)
NZ (1) NZ564156A (fr)
PE (1) PE20070203A1 (fr)
TW (1) TW200800254A (fr)
UA (1) UA93508C2 (fr)
WO (1) WO2007003384A1 (fr)
ZA (1) ZA200710615B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20080428A1 (es) 2006-07-18 2008-05-15 Glaxosmithkline Biolog Sa Vacunas para la malaria
US9717788B2 (en) 2007-03-02 2017-08-01 Glaxosmithkline Biologicals Sa Method of inducing an immune response against HIV employing HIV immunogens, adenoviral vectors encoding said immunogens, and adjuvant
CN105106971A (zh) * 2007-03-02 2015-12-02 葛兰素史密丝克莱恩生物有限公司 疫苗组合物及其在刺激免疫反应中的用途
BRPI0815199A2 (pt) * 2007-08-13 2015-03-31 Glaxosmithkline Biolog Sa Uso de um antígeno derivado da proteína circunsporozóite de plasmodium falciparum
CL2008003614A1 (es) * 2007-12-06 2010-01-15 Glaxosmithkline Biologicals Sa Vector de adenovirus de simio deficiente de replicacion c7 que comprende la proteina cs de p. falciparum o un fragmento de la misma; composicion que lo contiene en combinacion con un antigeno de malaria y un co-adyuvante; util en el tratamiento o profilaxis de la malaria.
BRPI0822098A2 (pt) * 2007-12-21 2015-06-30 Glaxosmithkline Biolog Sa Componente para uma vacina contra malária, vacina para malária, processo para a preparação do componente, uso do componente, e, método de tratar um paciente suscetível às infecções por plasmodium
TW200940087A (en) 2007-12-24 2009-10-01 Glaxosmithkline Biolog Sa Vaccines for malaria
GB0815872D0 (en) * 2008-09-01 2008-10-08 Pasteur Institut Novel method and compositions
WO2011115684A2 (fr) 2010-03-19 2011-09-22 Massachusetts Institute Of Technology Compositions de vésicules lipidiques et procédés pour les utiliser
US9149432B2 (en) 2010-03-19 2015-10-06 Massachusetts Institute Of Technology Lipid vesicle compositions and methods of use
EP2566506B1 (fr) * 2010-05-07 2016-07-06 Virbac Composition vaccinale destinee a la prevention ou au traitement des leishmanioses
US9249191B2 (en) 2012-02-16 2016-02-02 Vlp Therapeutics, Llc Virus like particle composition
CN105431535A (zh) * 2013-06-03 2016-03-23 Vlp治疗有限责任公司 疟疾疫苗
US9637532B2 (en) 2013-07-12 2017-05-02 Vlp Therapeutics, Llc Virus like particle comprising PD-1 antigen or PD-1 ligand antigen
WO2015091734A1 (fr) * 2013-12-20 2015-06-25 Glaxosmithkline Biologicals S.A. Nouveaux vaccins contre la malaria
CN106104258B (zh) * 2014-02-05 2019-11-29 莫纳什大学 快速检测疟疾的系统
JP6824154B2 (ja) 2014-08-08 2021-02-03 ブイエルピー・セラピューティクス・リミテッド・ライアビリティ・カンパニーＶＬＰ Ｔｈｅｒａｐｅｕｔｉｃｓ， ＬＬＣ 修飾エンベロープタンパク質ｅ３を含むウイルス様粒子
US10385101B2 (en) 2014-08-08 2019-08-20 Vlp Therapeutics, Llc Virus like particle comprising modified envelope protein E3
CN106687590B (zh) 2014-09-11 2021-08-03 Vlp治疗公司 黄热病毒病毒样颗粒
WO2016184784A1 (fr) 2015-05-15 2016-11-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Peptides comprenant le domaine de liaison des protéines de plasmodium falciparum (cbp1 et cbp2) à cx3cl1 de chimiokine
US11066464B2 (en) 2016-03-21 2021-07-20 Kymab Limited Anti-malarial antibodies that bind circumsporozoite protein
WO2018209265A1 (fr) * 2017-05-11 2018-11-15 Atreca, Inc. Anticorps antipaludéens qui se lient à la protéine circumsporozoïte
WO2020193520A1 (fr) 2019-03-25 2020-10-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Traitement de troubles de tauopathie par ciblage de nouvelles espèces tau

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Also Published As

Publication number Publication date
EA200702633A1 (ru) 2008-06-30
ES2529577T3 (es) 2015-02-23
CN101208100A (zh) 2008-06-25
AU2006265329A1 (en) 2007-01-11
ZA200710615B (en) 2009-02-25
BRPI0613087A2 (pt) 2012-10-09
EP1896060B1 (fr) 2014-12-03
WO2007003384A1 (fr) 2007-01-11
NZ564156A (en) 2011-08-26
UA93508C2 (en) 2011-02-25
KR20130111648A (ko) 2013-10-10
JP2008544969A (ja) 2008-12-11
IL187769A0 (en) 2008-08-07
NO20076200L (no) 2008-03-27
GB0513421D0 (en) 2005-08-03
PE20070203A1 (es) 2007-03-28
TW200800254A (en) 2008-01-01
US9279006B2 (en) 2016-03-08
US20080317787A1 (en) 2008-12-25
KR20080030640A (ko) 2008-04-04
CA2613057C (fr) 2016-02-02
JP5486802B2 (ja) 2014-05-07
AR055069A1 (es) 2007-08-01
EP1896060A1 (fr) 2008-03-12
AU2006265329B2 (en) 2012-12-20
MX2007016240A (es) 2008-03-07
CA2613057A1 (fr) 2007-01-11

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