CA2156525A1 - Compositions a base de lipide a monophosphoryle 3-o-desacyle pour des vaccins anti-grippe - Google Patents
Compositions a base de lipide a monophosphoryle 3-o-desacyle pour des vaccins anti-grippeInfo
- Publication number
- CA2156525A1 CA2156525A1 CA002156525A CA2156525A CA2156525A1 CA 2156525 A1 CA2156525 A1 CA 2156525A1 CA 002156525 A CA002156525 A CA 002156525A CA 2156525 A CA2156525 A CA 2156525A CA 2156525 A1 CA2156525 A1 CA 2156525A1
- Authority
- CA
- Canada
- Prior art keywords
- mpl
- vaccine composition
- composition according
- protein
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2153593A | 1993-02-19 | 1993-02-19 | |
US08/021,535 | 1993-02-19 | ||
US11575093A | 1993-09-01 | 1993-09-01 | |
US08/115,750 | 1993-09-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2156525A1 true CA2156525A1 (fr) | 1994-09-01 |
Family
ID=26694802
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002156525A Abandoned CA2156525A1 (fr) | 1993-02-19 | 1994-02-15 | Compositions a base de lipide a monophosphoryle 3-o-desacyle pour des vaccins anti-grippe |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0684838A1 (fr) |
AP (1) | AP431A (fr) |
AU (1) | AU6141094A (fr) |
CA (1) | CA2156525A1 (fr) |
IL (1) | IL108681A0 (fr) |
MA (1) | MA23118A1 (fr) |
MX (1) | MX9401225A (fr) |
SI (1) | SI9400085A (fr) |
WO (1) | WO1994019013A1 (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9105992D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
DK0812593T4 (da) * | 1993-03-23 | 2008-05-13 | Smithkline Beecham Biolog | Vaccinepræparater indeholdende 3-O-deacyleret monophosphoryllipid-A |
UA56132C2 (uk) * | 1995-04-25 | 2003-05-15 | Смітклайн Бічем Байолоджікалс С.А. | Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини |
US6306404B1 (en) | 1998-07-14 | 2001-10-23 | American Cyanamid Company | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
GB9820525D0 (en) * | 1998-09-21 | 1998-11-11 | Allergy Therapeutics Ltd | Formulation |
US6261573B1 (en) * | 1998-10-30 | 2001-07-17 | Avant Immunotherapeutics, Inc. | Immunoadjuvants |
AT407958B (de) | 1999-02-11 | 2001-07-25 | Immuno Ag | Inaktivierte influenza-virus-vakzine zur nasalen oder oralen applikation |
US6635261B2 (en) | 1999-07-13 | 2003-10-21 | Wyeth Holdings Corporation | Adjuvant and vaccine compositions containing monophosphoryl lipid A |
GB9923176D0 (en) * | 1999-09-30 | 1999-12-01 | Smithkline Beecham Biolog | Novel composition |
WO2002067983A1 (fr) * | 2001-02-23 | 2002-09-06 | Glaxosmithkline Biologicals S.A. | Nouveau vaccin |
WO2002074336A2 (fr) * | 2001-02-23 | 2002-09-26 | Glaxosmithkline Biologicals S.A. | Vaccin |
CA2445120A1 (fr) * | 2001-04-27 | 2002-11-07 | Glaxosmithkline Biologicals Sa | Nouveau vaccin |
ES2386272T3 (es) | 2004-09-09 | 2012-08-16 | Novartis Vaccines And Diagnostics Gmbh | Reducción de riesgos iatrogénicos potenciales asociados a las vacunas antigripales |
AU2005314563B2 (en) | 2004-11-03 | 2011-06-30 | Seqirus UK Limited | Influenza vaccination |
PT1861120T (pt) | 2005-03-23 | 2016-08-18 | Glaxosmithkline Biologicals Sa | Utilização de um vírus influenza e de um adjuvante de emulsão óleo-em-água para induzir células t cd4 e/ou melhorar a resposta de células b de memória |
MX2009000660A (es) | 2006-07-17 | 2009-04-08 | Glaxosmithkline Biolog Sa | Vacuna de influenza. |
BRPI0721393B8 (pt) * | 2007-03-22 | 2022-09-06 | Fund Butantan | método para obter lipídeo a monofosforilado da bordetella pertussis como um subproduto da produção de vacina celular contra coqueluche |
PE20090146A1 (es) | 2007-04-20 | 2009-03-23 | Glaxosmithkline Biolog Sa | Composicion inmunogenica contra el virus influenza |
EA201071086A1 (ru) * | 2008-03-18 | 2011-04-29 | Новартис Аг | Усовершенствованный способ получения вакцинных антигенов вируса гриппа |
EP3012330A1 (fr) | 2010-09-07 | 2016-04-27 | Novartis AG | Dosages génériques de détection de réovirus de mammifère |
SG10201808312YA (en) * | 2014-03-25 | 2018-10-30 | The Government Of The Us Secretary Of The Army | Methods for enhancing the immunostimulation potency of aluminum salt-adsorbed vaccines |
AU2019302562A1 (en) * | 2018-07-10 | 2021-01-14 | Seqirus Pty Ltd | Removal of agglomerates |
CN112361796A (zh) * | 2020-11-13 | 2021-02-12 | 安徽省天长市周氏羊业有限公司 | 一种秸秆回收储存前破碎干燥装置 |
CN114989269B (zh) * | 2022-06-30 | 2023-09-19 | 天康制药股份有限公司 | 一种牛赤羽免疫原性抗原及疫苗 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL79114A (en) * | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
US5230899A (en) * | 1985-08-07 | 1993-07-27 | Smithkline Beecham Corporation | Methods and compositions for making liposomes |
US4912094B1 (en) * | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
AU631377B2 (en) * | 1988-08-25 | 1992-11-26 | Liposome Company, Inc., The | Affinity associated vaccine |
AU640348B2 (en) * | 1988-08-31 | 1993-08-26 | Smithkline Beecham Corporation | Vaccinal Polypeptides |
DK425789A (da) * | 1988-08-31 | 1990-03-01 | Smithkline Beecham Corp | Vaccinale polypeptider |
EP0644201A1 (fr) * | 1990-09-28 | 1995-03-22 | SMITHKLINE BEECHAM BIOLOGICALS s.a. | Dérivés de gp160 et vaccines à base de gp160 ou d'un de ses dérivés, contenant un adjuvant |
WO1992011291A1 (fr) * | 1990-12-20 | 1992-07-09 | Smithkline Beecham Biologicals (S.A.) | VACCINS A BASE DE l'ANTIGENE D'ENVELOPPE DU VIRUS DE L'HEPATITE B |
FR2671974A1 (fr) * | 1991-01-24 | 1992-07-31 | Pasteur Merieux Serums Vacc | Composition vaccinale contre la grippe, a effet synergique, contenant comme additif du core de virus grippal. |
GB9105992D0 (en) * | 1991-03-21 | 1991-05-08 | Smithkline Beecham Biolog | Vaccine |
KR100278157B1 (ko) * | 1992-06-25 | 2001-01-15 | 장 스테판느 | 보조약을 함유하는 백신 조성물 |
-
1994
- 1994-02-15 EP EP94908327A patent/EP0684838A1/fr not_active Withdrawn
- 1994-02-15 WO PCT/EP1994/000448 patent/WO1994019013A1/fr not_active Application Discontinuation
- 1994-02-15 AU AU61410/94A patent/AU6141094A/en not_active Abandoned
- 1994-02-15 CA CA002156525A patent/CA2156525A1/fr not_active Abandoned
- 1994-02-17 MA MA23425A patent/MA23118A1/fr unknown
- 1994-02-17 AP APAP/P/1994/000621A patent/AP431A/en active
- 1994-02-17 IL IL10868194A patent/IL108681A0/xx unknown
- 1994-02-17 MX MX9401225A patent/MX9401225A/es unknown
- 1994-02-18 SI SI9400085A patent/SI9400085A/sl unknown
Also Published As
Publication number | Publication date |
---|---|
AP431A (en) | 1995-11-15 |
EP0684838A1 (fr) | 1995-12-06 |
AU6141094A (en) | 1994-09-14 |
WO1994019013A1 (fr) | 1994-09-01 |
AP9400621A0 (en) | 1994-04-30 |
MA23118A1 (fr) | 1994-10-01 |
SI9400085A (en) | 1994-09-30 |
IL108681A0 (en) | 1994-05-30 |
MX9401225A (es) | 1994-08-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |