MA29488B1 - Peptides et mimetiques de peptides destines a traiter les pathologies caracterisees par une reaction inflammatoire - Google Patents

Peptides et mimetiques de peptides destines a traiter les pathologies caracterisees par une reaction inflammatoire

Info

Publication number
MA29488B1
MA29488B1 MA30425A MA30425A MA29488B1 MA 29488 B1 MA29488 B1 MA 29488B1 MA 30425 A MA30425 A MA 30425A MA 30425 A MA30425 A MA 30425A MA 29488 B1 MA29488 B1 MA 29488B1
Authority
MA
Morocco
Prior art keywords
peptides
mimetics
pathologies characterized
inflammatory reaction
treating pathologies
Prior art date
Application number
MA30425A
Other languages
English (en)
Inventor
Alan M Fogelman
Mohamad Navab
Gattadahalli M Anantharamalah
Original Assignee
Univ California
Univ Alabama Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Univ Alabama Res Found filed Critical Univ California
Publication of MA29488B1 publication Critical patent/MA29488B1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775Apolipopeptides
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
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    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
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    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
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    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
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    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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Abstract

L'INVENTION CONCERNE DE NOUVEAUX AGENTS ACTIFS (TELS QUE PEPTIDES, PETITES MOLÉCULES ORGANIQUES, PAIRES D'ACIDES AMINÉS, ETC.) QUI SONT DES PEPTIDES AMÉLIORANT UN OU PLUSIEURS SYMPTÔMES DE L'ATHÉROSCLÉROSE ET/OU D'AUTRES PATHOLOGIES CARACTÉRISÉES PAR UNE RÉACTION INFLAMMATOIRE. DANS UN MODE DE RÉALISATION, LES PEPTIDES RESSEMBLENT À L'HÉLICE G* AMPHIPATHIQUE DE L'APOLIPOPROTÉINE J. LES AGENTS SONT HAUTEMENT STABLES ET PEUVENT FACILEMENT ÊTRE ADMINISTRÉS PAR VOIE ORALE
MA30425A 2005-04-29 2007-11-27 Peptides et mimetiques de peptides destines a traiter les pathologies caracterisees par une reaction inflammatoire MA29488B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67643105P 2005-04-29 2005-04-29
US69749505P 2005-07-07 2005-07-07

Publications (1)

Publication Number Publication Date
MA29488B1 true MA29488B1 (fr) 2008-05-02

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MA30425A MA29488B1 (fr) 2005-04-29 2007-11-27 Peptides et mimetiques de peptides destines a traiter les pathologies caracterisees par une reaction inflammatoire

Country Status (17)

Country Link
US (1) US20100227825A1 (fr)
EP (3) EP2269623A1 (fr)
JP (1) JP2008539235A (fr)
KR (1) KR20080007491A (fr)
AU (1) AU2006242651B2 (fr)
BR (1) BRPI0610983A2 (fr)
CA (1) CA2607483A1 (fr)
EA (2) EA200900786A1 (fr)
EC (1) ECSP077829A (fr)
IL (1) IL186959A0 (fr)
MA (1) MA29488B1 (fr)
MX (1) MX2007013430A (fr)
NO (1) NO20076022L (fr)
NZ (2) NZ563187A (fr)
SG (1) SG173373A1 (fr)
TN (1) TNSN07396A1 (fr)
WO (1) WO2006118805A2 (fr)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
US7723303B2 (en) * 2000-08-24 2010-05-25 The Regents Of The University Of California Peptides and peptide mimetics to treat pathologies characterized by an inflammatory response
US7199102B2 (en) * 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
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