MA31905B1 - DERIVES D'AMIDES DE L'ACIDE 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha] IMIDAZOLE-3-CARBOXYLIQUE - Google Patents
DERIVES D'AMIDES DE L'ACIDE 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha] IMIDAZOLE-3-CARBOXYLIQUEInfo
- Publication number
- MA31905B1 MA31905B1 MA32900A MA32900A MA31905B1 MA 31905 B1 MA31905 B1 MA 31905B1 MA 32900 A MA32900 A MA 32900A MA 32900 A MA32900 A MA 32900A MA 31905 B1 MA31905 B1 MA 31905B1
- Authority
- MA
- Morocco
- Prior art keywords
- imidazo
- dihydro
- imidazole
- carboxylic acid
- amide derivatives
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Toxicology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention concerne des dérivés d'amide de l'acide 6,7-dihydro-5h-imidazo[1,2-a]imidazole-3-carboxylique qui présentent un bon effet d'inhibition sur l'interaction des cam (molécules d'adhésion cellulaire) et des intégrines leucocytaires et sont donc utiles dans le traitement d'une maladie inflammatoire.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99096007P | 2007-11-29 | 2007-11-29 | |
US4795708P | 2008-04-25 | 2008-04-25 | |
PCT/US2008/084149 WO2009070485A1 (fr) | 2007-11-29 | 2008-11-20 | Dérivés d'amides de l'acide 6,7-dihydro-5h-imidazo[1,2-α]imidazole-3-carboxylique |
Publications (1)
Publication Number | Publication Date |
---|---|
MA31905B1 true MA31905B1 (fr) | 2010-12-01 |
Family
ID=40193954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA32900A MA31905B1 (fr) | 2007-11-29 | 2010-06-09 | DERIVES D'AMIDES DE L'ACIDE 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha] IMIDAZOLE-3-CARBOXYLIQUE |
Country Status (32)
Country | Link |
---|---|
US (1) | US8552205B2 (fr) |
EP (1) | EP2225238B1 (fr) |
JP (1) | JP5485164B2 (fr) |
KR (1) | KR20100101095A (fr) |
CN (1) | CN101889011B (fr) |
AR (1) | AR069513A1 (fr) |
AU (1) | AU2008329909B2 (fr) |
BR (1) | BRPI0819831A2 (fr) |
CA (1) | CA2705583A1 (fr) |
CL (1) | CL2008003576A1 (fr) |
CO (1) | CO6210701A2 (fr) |
CY (1) | CY1115857T1 (fr) |
DK (1) | DK2225238T3 (fr) |
EA (1) | EA017688B1 (fr) |
EC (1) | ECSP10010196A (fr) |
ES (1) | ES2525237T3 (fr) |
HK (1) | HK1145683A1 (fr) |
HR (1) | HRP20141171T1 (fr) |
IL (1) | IL205189A (fr) |
MA (1) | MA31905B1 (fr) |
MX (1) | MX2010004995A (fr) |
MY (1) | MY151004A (fr) |
NZ (1) | NZ585640A (fr) |
PE (1) | PE20091427A1 (fr) |
PL (1) | PL2225238T3 (fr) |
PT (1) | PT2225238E (fr) |
RS (1) | RS53602B1 (fr) |
SI (1) | SI2225238T1 (fr) |
TN (1) | TN2010000240A1 (fr) |
TW (2) | TWI475990B (fr) |
UY (1) | UY31493A1 (fr) |
WO (1) | WO2009070485A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2446352T3 (es) * | 2009-06-02 | 2014-03-07 | Boehringer Ingelheim International Gmbh | Derivados de amidas del ácido 6,7-dihidro-5H-imidazo[1,2-a]imidazol-3-carboxílico |
WO2010141330A1 (fr) * | 2009-06-02 | 2010-12-09 | Boehringer Ingelheim International Gmbh | Dérivés d'amides d'acide 6,7-dihydro-5h-imidazo [1,2-a] imidazole-3-carboxylique |
US9056858B2 (en) | 2009-10-21 | 2015-06-16 | Boehringer Ingelheim International Gmbh | Indazole and pyrazolopyridine compounds as CCR1 receptor antagonists |
US8912221B2 (en) * | 2010-12-27 | 2014-12-16 | Hoffmann-La Roche Inc. | Biaryl amide derivatives |
SG194621A1 (en) * | 2011-04-27 | 2013-12-30 | Shionogi & Co | 5-membered ring aromatic heterocyclic derivative having npy y5 receptor antagonistic activity |
TW201311678A (zh) | 2011-08-03 | 2013-03-16 | Kyowa Hakko Kirin Co Ltd | 二苯并氧呯衍生物 |
KR102049534B1 (ko) | 2011-10-03 | 2019-11-27 | 오게다 에스.에이. | 선택적 NK-3 수용체 길항제로서의 신규한 키랄 N-아실-5,6,7,(8-치환된)-테트라히드로-[1,2,4]트리아졸로[4,3-a]피라진, 의약 조성물, NK-3 수용체 매개 질환에 사용하는 방법 및 그의 키랄 합성법 |
WO2016058896A1 (fr) | 2014-10-14 | 2016-04-21 | Syngenta Participations Ag | Procédé pour la préparation de 1-(3,5-dichloro-4-fluorophényl)-2,2,2-trifluoroéthanone |
JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
CN106631827B (zh) * | 2016-12-30 | 2018-10-23 | 上海毕得医药科技有限公司 | 一种(1-环丙基-1-甲基)乙基胺及其盐酸盐的合成方法 |
CN109369432B (zh) * | 2018-11-02 | 2021-06-25 | 永农生物科学有限公司 | (s)-4-氯-2-氨基丁酸酯的制备方法 |
JP2023506917A (ja) | 2019-12-20 | 2023-02-20 | バイエル・アクチエンゲゼルシヤフト | 置換チオフェンカルボキサミド、チオフェンカルボン酸およびその誘導体 |
CN111848521A (zh) * | 2020-08-26 | 2020-10-30 | 韶远科技(上海)有限公司 | 一种2-取代-4-烷氧基咪唑化合物的制备方法 |
WO2024013736A1 (fr) * | 2022-07-12 | 2024-01-18 | Adama Makhteshim Ltd. | Procédé de préparation de benzamides substitués |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
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FR2015493A1 (fr) | 1968-08-12 | 1970-04-30 | Sumitomo Chemical Co | |
DK123717B (da) | 1968-11-25 | 1972-07-24 | Sumitomo Chemical Co | 3-(3',5'-Dihalogenphenyl)-imidazolidin-2,4-dionderivater med mirobicid virkning. |
JPS5136332B1 (fr) | 1970-12-09 | 1976-10-07 | ||
EP0091596B1 (fr) | 1982-04-08 | 1991-09-11 | Shell Internationale Researchmaatschappij B.V. | Hydantoins, préparation et application |
JPS63270665A (ja) | 1987-04-30 | 1988-11-08 | Wakamoto Pharmaceut Co Ltd | イミダゾ−ル誘導体 |
JPS63270667A (ja) | 1987-04-30 | 1988-11-08 | Wakamoto Pharmaceut Co Ltd | 1−ベンジルイミダゾ−ル誘導体 |
US5306822A (en) | 1988-05-25 | 1994-04-26 | Warner-Lambert Company | Arylmethylenyl derivatives of oxazolidinone |
IE940525L (en) | 1988-05-25 | 1989-11-25 | Warner Lambert Co | Known and selected novel arylmethylenyl derivatives of¹thiazolidinones, imidazolidinones and oxazolidinones useful¹as antiallergy agents and antiinflammatory agents |
US5208250A (en) | 1988-05-25 | 1993-05-04 | Warner-Lambert Company | Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents |
US4977270A (en) | 1988-12-01 | 1990-12-11 | Ici Americas Inc. | Substituted 2,4-dioxodiazolidines and -thiadiazolidines and their use as herbicides |
US4911748A (en) | 1988-12-22 | 1990-03-27 | Ici Americas Inc. | Herbicidal 5-substituted-3-phenyl-imidazolidine-2,4-diones |
JPH04273877A (ja) | 1991-02-28 | 1992-09-30 | Sumitomo Pharmaceut Co Ltd | 新規なイミダゾール誘導体 |
CA2083891A1 (fr) | 1991-12-03 | 1993-06-04 | Angus Murray Macleod | Composes heterocycliques, compositions et utilisation therapeutique |
JPH05188631A (ja) | 1992-01-10 | 1993-07-30 | Mita Ind Co Ltd | 電子写真感光体 |
TW521073B (en) | 1994-01-05 | 2003-02-21 | Hoechst Marion Roussel Inc | New optionally substituted phenylimidazolidines, their preparation process, their use as anti-androgenic agent and the pharmaceutical compositions containing them |
US20040006011A1 (en) | 1996-07-12 | 2004-01-08 | Gour Barbara J. | Peptidomimetic modulators of cell adhesion |
JP2001525797A (ja) | 1996-10-28 | 2001-12-11 | ザ ユニバーシティ オブ ワシントン | ウイルスrnaへのミスコーディングリボヌクレオシドアナログの組込みによるウイルス変異の誘導 |
BR9811260A (pt) | 1997-03-03 | 2000-08-08 | Boehringer Ingelheim Pharma | Pequenas moléculas úteis no tratamento de doença inflamatória |
US6355664B1 (en) | 1997-03-03 | 2002-03-12 | Boehringer Ingelheim Pharmaceuticals, Inc. | Phenylpyrrolidines, phenylimidazolidines, 3-phenyl-1,3-oxizolidines and 3-phenyl-1,3-thiazolidines and their use in the treatment of inflammatory disease |
NZ502872A (en) | 1997-08-28 | 2002-10-25 | Novartis Ag | Mevinolin and compaction as LFA-1 antagonists for treating autoimmune diseases |
EP1063982B1 (fr) | 1998-03-27 | 2007-02-14 | Genentech, Inc. | Antagonistes destines au traitement de troubles induits par le recepteur d'adhesion de cd11/cd18 |
WO2001007048A1 (fr) | 1999-07-21 | 2001-02-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Petites molecules utiles pour le traitement de troubles inflammatoires |
US6492408B1 (en) | 1999-07-21 | 2002-12-10 | Boehringer Ingelheim Pharmaceuticals, Inc. | Small molecules useful in the treatment of inflammatory disease |
WO2001007052A1 (fr) | 1999-07-21 | 2001-02-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Petites molecules des plus utiles dans le traitement de maladies inflammatoires |
WO2001007044A1 (fr) | 1999-07-21 | 2001-02-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Petites molecules utiles pour le traitement de maladies inflammatoires |
WO2001006984A2 (fr) | 1999-07-21 | 2001-02-01 | Boehringer Ingelheim Pharmaceuticals, Inc. | Petites particules utiles pour le traitement de maladies inflammatoires |
MXPA02003977A (es) | 1999-10-20 | 2003-09-25 | Tanabe Seiyaku Co | Inhibidores de adhesion de celula mediada por al°2. |
WO2002050080A1 (fr) | 2000-12-19 | 2002-06-27 | Boehringer Ingelheim Pharmaceuticals, Inc. | Petites molecules utiles dans le traitement de maladies inflammatoires |
RU2003126188A (ru) * | 2001-01-26 | 2005-03-27 | Бристол-Маерс Сквибб Компани (Us) | Имидазолильные производные как ингибиторы кортикотропин-рилизинг фактора |
US20030232817A1 (en) | 2002-05-29 | 2003-12-18 | Boehringer Ingelheim Pharmaceuticals, Inc. | Small molecules useful for the treatment of inflammatory disease |
US6844360B2 (en) | 2002-10-30 | 2005-01-18 | Boehringer Ingelheim Pharmaceuticals, Inc. | Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide |
US6852748B1 (en) | 2002-10-30 | 2005-02-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide |
WO2006014828A1 (fr) | 2004-07-27 | 2006-02-09 | Boehringer Ingelheim International, Gmbh | Synthese d'amides d'acide 6,7-dihydro-5h-imidazo[1,2-a]imidazole-3-sulfonique |
US7572921B2 (en) | 2005-04-05 | 2009-08-11 | Boehringer Ingelheim International Gmbh | Substituted benzylimidazoles useful for the treatment of inflammatory diseases |
EP1868603A1 (fr) | 2005-04-06 | 2007-12-26 | Boehringer Ingelheim Pharma GmbH & Co. KG | Derives d'amides, esters et acides ý6,7-dihydro-5h-imidazo ý1,2-alpha¨imidazole-3-sulfonyl¨-azetedino-carboxyliques et leur utilisation comme anti-inflammatoires |
KR20080025067A (ko) * | 2005-05-19 | 2008-03-19 | 베링거 인겔하임 인터내셔날 게엠베하 | 6,7-디하이드로-5H-이미다조[1,2-a]이미다졸-3-설폰산의유도체 |
TW200831488A (en) | 2006-11-29 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
RU2483072C2 (ru) | 2007-11-29 | 2013-05-27 | Актелион Фармасьютиклз Лтд | Производные фосфоновой кислоты и их применение в качестве антагонистов рецептора p2y12 |
CL2008003511A1 (es) | 2007-11-29 | 2010-02-19 | Metabasis Therapeutics Inc | Compuestos derivados nucleotidicos, inhibidores de polimerasa ns5b del virus de la hepatitis c; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c. |
JP2009149609A (ja) | 2007-11-29 | 2009-07-09 | Sumitomo Chemical Co Ltd | アミド化合物及びその用途 |
EP2080758A3 (fr) | 2007-11-29 | 2009-08-26 | Bayer CropScience AG | Delta-1-pyrrolines substituées par halogène |
WO2010141330A1 (fr) | 2009-06-02 | 2010-12-09 | Boehringer Ingelheim International Gmbh | Dérivés d'amides d'acide 6,7-dihydro-5h-imidazo [1,2-a] imidazole-3-carboxylique |
ES2446352T3 (es) | 2009-06-02 | 2014-03-07 | Boehringer Ingelheim International Gmbh | Derivados de amidas del ácido 6,7-dihidro-5H-imidazo[1,2-a]imidazol-3-carboxílico |
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2008
- 2008-11-20 NZ NZ585640A patent/NZ585640A/en not_active IP Right Cessation
- 2008-11-20 ES ES08853791.5T patent/ES2525237T3/es active Active
- 2008-11-20 EP EP08853791.5A patent/EP2225238B1/fr active Active
- 2008-11-20 AU AU2008329909A patent/AU2008329909B2/en not_active Ceased
- 2008-11-20 CA CA2705583A patent/CA2705583A1/fr not_active Abandoned
- 2008-11-20 PT PT88537915T patent/PT2225238E/pt unknown
- 2008-11-20 BR BRPI0819831A patent/BRPI0819831A2/pt not_active IP Right Cessation
- 2008-11-20 US US12/745,439 patent/US8552205B2/en active Active
- 2008-11-20 MY MYPI20102238 patent/MY151004A/en unknown
- 2008-11-20 RS RSP20140622 patent/RS53602B1/en unknown
- 2008-11-20 SI SI200831320T patent/SI2225238T1/sl unknown
- 2008-11-20 CN CN200880118561.4A patent/CN101889011B/zh not_active Expired - Fee Related
- 2008-11-20 PL PL08853791T patent/PL2225238T3/pl unknown
- 2008-11-20 EA EA201000866A patent/EA017688B1/ru not_active IP Right Cessation
- 2008-11-20 MX MX2010004995A patent/MX2010004995A/es active IP Right Grant
- 2008-11-20 KR KR1020107011875A patent/KR20100101095A/ko not_active Application Discontinuation
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- 2008-11-20 DK DK08853791.5T patent/DK2225238T3/en active
- 2008-11-20 WO PCT/US2008/084149 patent/WO2009070485A1/fr active Application Filing
- 2008-11-27 PE PE2008001991A patent/PE20091427A1/es not_active Application Discontinuation
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2014
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