LV12452B - Aktīvās vielas vagināla ievadīšanas sistēma - Google Patents
Aktīvās vielas vagināla ievadīšanas sistēma Download PDFInfo
- Publication number
- LV12452B LV12452B LVP-99-169A LV990169A LV12452B LV 12452 B LV12452 B LV 12452B LV 990169 A LV990169 A LV 990169A LV 12452 B LV12452 B LV 12452B
- Authority
- LV
- Latvia
- Prior art keywords
- sleeve
- support means
- delivery system
- active
- core
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
- A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
- A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Claims (11)
- LV 12452 IZGUDROJUMA FORMULA 1. Aktīvās vielas vagināla ievadīšanas sistēma, kas satur elastīgus atbalsta līdzekļus un padeves līdzekļus, kurus balsta atbalsta līdzekļi un kuri satur aktīvo vielu, raksturojas ar to, ka atbalsta līdzekļi (1) sastāv no serdeņa (Γ) būtībā ar atvērta gredzena formu un ka padeves līdzekļi sastāv vismaz no viena uzmavai līdzīga ķermeņa (2) no polimēra materiāla, kas daļā 10 serdeņa garuma jostveidīgi apņem serdeni.
- 2. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka uzmavai līdzīgais ķermenis ir no polisiloksāna, piemēram no polidimetilsiloksāna, poliuretāna vai etilvinilacetāta (EVA) kopolimēra. 15
- 3. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka atbalsta līdzekļi sastāv no sašūta kaučuka, piemēram dabiskā kaučuka, butilkaučuka un polidimetilsiloksāna elastomēra, elastīgiem termoplastiskiem sveķiem, piemēram etilvinilacetāta (EVA), termoplastiska elastomēra, 20 piemēram stirola kopolimēra (SEBS, SBS, SIS), poliuretāna vai termoplastiska poliolefīna.
- 4. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka uzmavai līdzīgā ķermeņa iekšējā virsma kontaktē ar tāda materiāla slāni, kas 25 būtībā novērš aktīvās vielas migrāciju no uzmavai līdzīgā ķermeņa atbalsta līdzekļos.
- 5. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka atbalsta līdzekļu ārējā virsma vai atbalsta līdzekļi pilnībā ir izgatavoti no 30 materiāla, kas novērš aktīvās vielas migrāciju no uzmavai līdzīgā ķermeņa atbalsta līdzekļos.
- 6. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka padeves līdzekļi ir veidoti no diviem uzmavai līdzīgiem ķermeņiem, pie tam 35 katrs no tiem satur citu aktīvo vielu. 2
- 7. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka uzmavai līdzīgais ķermenis satur gestagēnu aktīvo vielu vai estrogēnu aktīvo vielu.
- 8. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka tā satur divus uzmavai līdzīgos ķermeņus, pie tam tie abi satur vienu un to pašu aktīvo vielu.
- 9. Ievadīšanas sistēma saskaņā ar 1. punktu, kas raksturojas ar to, ka 10 uzmavai līdzīgais ķermenis ir pārklāts ar membrānu (4), kas ļauj difundēt aktīvajai vielai, galvenokārt ar poiisiloksāna membrānu.
- 10. Paņēmiens ievadīšanas sistēmas saskaņā ar 1. punktu izgatavošanai, raksturojas ar to, ka tiek palielināts aktīvo vielu un polimēru saturošā 15 uzmavai līdzīgā ķermeņa diametrs, piemēram izstiepjot, piemēram mehāniski vai uzbriedinot, šādā stāvoklī tas tiek novietots uz serdeņa un tiek atstāts, lai savilktos uz atbalsta līdzekļiem.
- 11. Paņēmiens saskaņā ar 10. punktu, kas raksturojas ar to, ka uzmavai 20 līdzīgais ķermenis ir izgatavots koekstrūzijas ceļā kopā ar polimēra membrānu, kas tiek darīts, lai uz uzmavas veidotu ārējo slāni, kad tā uzmontēta uz serdeņa.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI932789A FI95768C (fi) | 1993-06-17 | 1993-06-17 | Emättimensisäinen antosysteemi |
Publications (2)
Publication Number | Publication Date |
---|---|
LV12452A LV12452A (lv) | 2000-04-20 |
LV12452B true LV12452B (lv) | 2000-09-20 |
Family
ID=8538154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LVP-99-169A LV12452B (lv) | 1993-06-17 | 1999-12-01 | Aktīvās vielas vagināla ievadīšanas sistēma |
Country Status (24)
Country | Link |
---|---|
US (1) | US5694947A (lv) |
EP (1) | EP0703802B1 (lv) |
JP (1) | JP3803714B2 (lv) |
KR (1) | KR100312764B1 (lv) |
CN (1) | CN1126574C (lv) |
AT (1) | ATE177657T1 (lv) |
AU (1) | AU674758B2 (lv) |
BR (1) | BR9407118A (lv) |
CZ (1) | CZ284989B6 (lv) |
DE (1) | DE69417232T2 (lv) |
DK (1) | DK0703802T3 (lv) |
EE (1) | EE03202B1 (lv) |
ES (1) | ES2130423T3 (lv) |
FI (1) | FI95768C (lv) |
GR (1) | GR3030565T3 (lv) |
HU (1) | HU217950B (lv) |
LT (1) | LT3455B (lv) |
LV (1) | LV12452B (lv) |
MY (1) | MY113965A (lv) |
NO (1) | NO311498B1 (lv) |
PL (1) | PL176664B1 (lv) |
RU (1) | RU2121824C1 (lv) |
TW (1) | TW286273B (lv) |
WO (1) | WO1995000199A1 (lv) |
Families Citing this family (50)
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FI95768C (fi) * | 1993-06-17 | 1996-03-25 | Leiras Oy | Emättimensisäinen antosysteemi |
GB9522403D0 (en) * | 1995-11-01 | 1996-01-03 | Hoechst Roussel Ltd | Intravaginal drug delivery device |
US5972372A (en) * | 1996-07-31 | 1999-10-26 | The Population Council, Inc. | Intravaginal rings with insertable drug-containing core |
DE69929055T2 (de) * | 1998-05-01 | 2006-07-20 | Duramed Pharmaceuticals Inc., Cincinnati | Verfahren zur spritzgussherstellung von vorrichtungen mit kontrollierter wirkstofffreisetzung und damit hergestellte vorrichtung |
US6476079B1 (en) * | 1999-12-23 | 2002-11-05 | Leiras Oy | Devices for the delivery of drugs having antiprogestinic properties |
GB0009914D0 (en) | 2000-04-20 | 2000-06-07 | Metris Therapeutics Limited | Device |
WO2005004837A1 (en) * | 2003-07-10 | 2005-01-20 | Galen (Chemicals) Limited | Intravaginal drug delivery devices |
US7862552B2 (en) * | 2005-05-09 | 2011-01-04 | Boston Scientific Scimed, Inc. | Medical devices for treating urological and uterine conditions |
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JP2010509964A (ja) * | 2006-11-20 | 2010-04-02 | ナームローゼ・フエンノートチヤツプ・オルガノン | らせん形薬物送達システム |
TW200927141A (en) * | 2007-11-22 | 2009-07-01 | Bayer Schering Pharma Oy | Vaginal delivery system |
EP2062568A1 (en) * | 2007-11-22 | 2009-05-27 | Bayer Schering Pharma Oy | Vaginal delivery system |
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FI20095550A0 (fi) * | 2009-05-19 | 2009-05-19 | Bayer Schering Pharma Oy | Vaginaalinen antojärjestelmä |
FI20095563A (fi) * | 2009-05-20 | 2010-11-21 | Bayer Schering Pharma Oy | Vaginaalinen antojärjestelmä |
EP4108216A1 (en) | 2009-06-03 | 2022-12-28 | Forsight Vision5, Inc. | Anterior segment drug delivery |
DE102010003494A1 (de) * | 2010-03-31 | 2011-10-06 | Bayer Schering Pharma Aktiengesellschaft | Parenterales Abgabesystem, das Aromatasehemmer und Gestagene freisetzt, für die Behandlung von Endometriose |
US8939948B2 (en) | 2010-06-01 | 2015-01-27 | Forsight Vision5, Inc. | Ocular insert apparatus and methods |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
EP2749286B1 (en) | 2011-08-26 | 2017-03-01 | Universidad De Santiago De Chile | Use of non-steroidal anti-inflammatory drugs meloxicam and piroxicam, administered intravaginally, for interruption of a woman's ovulation process |
GB201115592D0 (en) * | 2011-09-09 | 2011-10-26 | Vivosens Medical Gmbh | Flexible ring pessary |
CN103007427B (zh) * | 2011-09-21 | 2016-01-20 | 上海市计划生育科学研究所 | 缓控释宫内释药器及其制备方法 |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
ES2885523T3 (es) | 2011-11-23 | 2021-12-14 | Therapeuticsmd Inc | Formulaciones y terapias de reposición hormonal de combinación naturales |
EP2641602A1 (en) | 2012-03-23 | 2013-09-25 | PregLem S.A. | Method for treating gynecological diseases |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
KR20150051234A (ko) | 2012-09-03 | 2015-05-11 | 에쏘세아 파르밍 에쎄.아. | 수생 생물종의 배향 및/또는 억제를 위한 저장조 케이지 침지 시스템 |
PT2911623T (pt) | 2012-10-26 | 2019-11-21 | Forsight Vision5 Inc | Sistema oftálmico para libertação prolongada de fármaco no olho |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
AR095831A1 (es) | 2013-04-10 | 2015-11-11 | Preglem Sa | Moduladores de los receptores de progesterona útiles en la terapia de los fibroides uterinos |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
CN106456838B (zh) * | 2014-04-01 | 2020-12-29 | 保利医学公司 | 避孕装置及相关装置 |
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CN109771124A (zh) * | 2019-01-31 | 2019-05-21 | 山东省药学科学院 | 一种具有形状记忆功能的子宫托 |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
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FI95768C (fi) * | 1993-06-17 | 1996-03-25 | Leiras Oy | Emättimensisäinen antosysteemi |
-
1993
- 1993-06-17 FI FI932789A patent/FI95768C/fi active
-
1994
- 1994-06-15 JP JP52252194A patent/JP3803714B2/ja not_active Expired - Fee Related
- 1994-06-15 RU RU96101160A patent/RU2121824C1/ru not_active IP Right Cessation
- 1994-06-15 HU HU9503290A patent/HU217950B/hu not_active IP Right Cessation
- 1994-06-15 MY MYPI94001519A patent/MY113965A/en unknown
- 1994-06-15 EP EP94917022A patent/EP0703802B1/en not_active Expired - Lifetime
- 1994-06-15 PL PL94312193A patent/PL176664B1/pl not_active IP Right Cessation
- 1994-06-15 CZ CZ953208A patent/CZ284989B6/cs not_active IP Right Cessation
- 1994-06-15 TW TW083105534A patent/TW286273B/zh not_active IP Right Cessation
- 1994-06-15 ES ES94917022T patent/ES2130423T3/es not_active Expired - Lifetime
- 1994-06-15 CN CN94192420A patent/CN1126574C/zh not_active Expired - Fee Related
- 1994-06-15 US US08/564,253 patent/US5694947A/en not_active Expired - Lifetime
- 1994-06-15 DE DE69417232T patent/DE69417232T2/de not_active Expired - Lifetime
- 1994-06-15 AT AT94917022T patent/ATE177657T1/de not_active IP Right Cessation
- 1994-06-15 DK DK94917022T patent/DK0703802T3/da active
- 1994-06-15 BR BR9407118A patent/BR9407118A/pt not_active IP Right Cessation
- 1994-06-15 KR KR1019950705668A patent/KR100312764B1/ko not_active IP Right Cessation
- 1994-06-15 WO PCT/FI1994/000255 patent/WO1995000199A1/en active IP Right Grant
- 1994-06-15 AU AU68481/94A patent/AU674758B2/en not_active Ceased
- 1994-06-16 LT LTIP1957A patent/LT3455B/lt not_active IP Right Cessation
- 1994-07-18 EE EE9400027A patent/EE03202B1/xx not_active IP Right Cessation
-
1995
- 1995-12-12 NO NO19955029A patent/NO311498B1/no not_active IP Right Cessation
-
1999
- 1999-06-17 GR GR990401648T patent/GR3030565T3/el unknown
- 1999-12-01 LV LVP-99-169A patent/LV12452B/lv unknown
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