LV12074B - Peptīds un tā iegūšanas paņēmiens - Google Patents

Peptīds un tā iegūšanas paņēmiens Download PDF

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Publication number
LV12074B
LV12074B LVP-97-266A LV970266A LV12074B LV 12074 B LV12074 B LV 12074B LV 970266 A LV970266 A LV 970266A LV 12074 B LV12074 B LV 12074B
Authority
LV
Latvia
Prior art keywords
trp
glu
phe
leu
pro
Prior art date
Application number
LVP-97-266A
Other languages
English (en)
Latvian (lv)
Other versions
LV12074A (lv
Inventor
Vladislav Deigin
Andrei Korotkov
Original Assignee
Immunotech Developments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20168146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LV12074(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunotech Developments Inc filed Critical Immunotech Developments Inc
Publication of LV12074A publication Critical patent/LV12074A/xx
Publication of LV12074B publication Critical patent/LV12074B/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LVP-97-266A 1995-06-07 1997-12-19 Peptīds un tā iegūšanas paņēmiens LV12074B (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU95108559A RU2107692C1 (ru) 1995-06-07 1995-06-07 Пептид и способ его получения
PCT/RU1996/000116 WO1996040740A1 (en) 1995-06-07 1996-05-06 Peptide and method of obtaining it

Publications (2)

Publication Number Publication Date
LV12074A LV12074A (lv) 1998-06-20
LV12074B true LV12074B (lv) 1998-08-20

Family

ID=20168146

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-97-266A LV12074B (lv) 1995-06-07 1997-12-19 Peptīds un tā iegūšanas paņēmiens

Country Status (20)

Country Link
US (1) US5736519A (cs)
EP (1) EP0832900B1 (cs)
JP (1) JP4082522B2 (cs)
CN (1) CN1154653C (cs)
AT (1) ATE260933T1 (cs)
AU (1) AU724781B2 (cs)
BR (1) BRPI9609235B8 (cs)
CA (1) CA2222296C (cs)
CZ (1) CZ287816B6 (cs)
DE (1) DE69631762T2 (cs)
DK (1) DK0832900T3 (cs)
ES (1) ES2217311T3 (cs)
HU (1) HU228461B1 (cs)
LT (1) LT4476B (cs)
LV (1) LV12074B (cs)
PT (1) PT832900E (cs)
RU (1) RU2107692C1 (cs)
SK (1) SK281825B6 (cs)
UA (1) UA48974C2 (cs)
WO (1) WO1996040740A1 (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2107691C1 (ru) * 1995-03-02 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
US5916878A (en) * 1995-11-28 1999-06-29 Edward T. Wei γ-glutamyl and β-aspartyl containing immunomodulator compounds and methods therewith
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis
DE19712633A1 (de) * 1997-03-26 1998-10-08 Laves Arzneimittel Verwendung von gamma-Aminobuttersäure als Interleukinbildungsstimulans
IL145926A0 (en) 2001-10-15 2002-07-25 Mor Research Applic Ltd Peptide epitopes of mimotopes useful in immunomodulation
US20060233863A1 (en) 2003-02-10 2006-10-19 Enzymotec Ltd. Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy
IL155136A0 (en) * 2003-02-10 2003-10-31 Enzymotec Ltd A composition for reducing blood cholesterol and triglycerides
UA80870C2 (en) * 2003-03-28 2007-11-12 Sciclone Pharmaceuticals Inc Method for treatment or prevention of aspergillus infections with thymosin alpha 1
BRPI0514244A (pt) * 2004-08-09 2008-06-03 Enzymotec Ltd produtos alimentìcios para diabéticos
RU2394576C2 (ru) 2004-08-10 2010-07-20 Энзимотек Лтд. Способы лечения, требующие фитокомпонентов
WO2006131833A2 (en) * 2005-03-18 2006-12-14 Centre National De La Recherche Scientifique New hybrid oligomers. their preparation process and pharmaceutical compositions containing them
CA2604133C (en) * 2005-04-07 2015-12-01 Centre National De La Recherche Scientifique Compounds useful as modulators of the proteasome activity
US20100129288A1 (en) * 2005-06-28 2010-05-27 Elior Peles Gliomedin, Fragments Thereof and Methods of Using Same
RU2320364C1 (ru) * 2006-08-21 2008-03-27 Закрытое Акционерное Общество "Центр "Пептос" Способ лечения злокачественных новообразований
CA2569204A1 (en) 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) * 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
MX2009008641A (es) 2007-02-13 2009-09-14 Sciclone Pharmaceuticals Inc Composiciones para el tratamiento o prevencion del deterioro, lesion o daño a tejido debido a enfermedad de las mucosas.
CA2579119C (en) 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
US20100150924A1 (en) * 2007-05-22 2010-06-17 Elior Peles Regulation of myelination by nectin-like (necl) molecules
RU2410391C1 (ru) * 2009-06-03 2011-01-27 Общество с ограниченной ответственностью "Пептос Фарма" Пептиды, влияющие на регенерацию кроветворной системы, и фармацевтическая композиция на их основе
AU2012234680A1 (en) * 2011-03-31 2013-10-17 Apotex Technologies Inc. Prodrugs of D-isoglutamyl-[D/L]-tryptophan
CN103502215A (zh) * 2011-03-31 2014-01-08 阿普泰克斯科技公司 D-γ-谷氨酰基-D-色氨酸和D-γ-谷氨酰基-L-色氨酸的前药
CN102417474B (zh) * 2011-09-26 2014-07-02 深圳翰宇药业股份有限公司 D-异谷氨酰基-d-色氨酸制备的新方法
RU2634258C1 (ru) * 2016-11-08 2017-10-24 федеральное государственное автономное образовательное учреждение высшего образования "Российский университет дружбы народов" (РУДН) Наполнитель для капсульного ингалятора

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832337A (en) * 1970-07-28 1974-08-27 Squibb & Sons Inc Peptide enzyme inhibitors
GB1526367A (en) * 1976-10-12 1978-09-27 Ici Ltd Polypeptide
HU184481B (en) * 1981-10-02 1984-08-28 Richter Gedeon Vegyeszet Process for producing tripeptides for diminishing appetite
JPS5921656A (ja) * 1982-07-28 1984-02-03 Takeda Chem Ind Ltd ポリペプチド誘導体
CH659586A5 (de) * 1985-07-02 1987-02-13 Le G Ped I Arzneimittel aus dem thymus und verfahren zu dessen herstellung.
CA1286989C (en) * 1985-12-26 1991-07-30 A. Arthur Gottlieb Immunoamplifiers and related compositions
IT1216908B (it) * 1987-03-19 1990-03-14 Eniricerche Spa Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.
DE3873327D1 (de) * 1987-12-30 1992-09-03 Vsesojuznyj Kardiologitsches Arzneimittelzubereitung zur behandlung des immunmangels.
US5021551A (en) * 1989-01-18 1991-06-04 Washington University Method of enhancing peptide immunogenicity
SU1737798A1 (ru) * 1989-04-11 1995-03-20 Институт клинической иммунологии СО АМН СССР Способ получения иммуностимулирующих тимусных полипептидов
IT1230733B (it) 1989-06-30 1991-10-29 Eniricerche Spa Analoghi della timopentina retro invertita a tutti i legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.
IT1263042B (it) * 1993-01-15 1996-07-24 Enichem Polimeri Composizione da stampaggio a base di polifenilenetere
AU7392294A (en) * 1993-07-21 1995-02-20 Vladimir Khatskelevich Khavinson Pharmaceutical with immunomodulating activity

Also Published As

Publication number Publication date
EP0832900A1 (en) 1998-04-01
LT4476B (lt) 1999-03-25
CA2222296A1 (en) 1996-12-19
DK0832900T3 (da) 2004-06-21
JPH11513016A (ja) 1999-11-09
EP0832900B1 (en) 2004-03-03
HUP9801990A2 (hu) 1999-02-01
WO1996040740A1 (en) 1996-12-19
DE69631762T2 (de) 2005-03-10
ATE260933T1 (de) 2004-03-15
RU2107692C1 (ru) 1998-03-27
CZ390597A3 (cs) 1998-08-12
HUP9801990A3 (en) 1999-06-28
SK166997A3 (en) 1998-04-08
BR9609235A (pt) 1999-12-21
AU724781B2 (en) 2000-09-28
LV12074A (lv) 1998-06-20
CN1189837A (zh) 1998-08-05
EP0832900A4 (en) 1999-10-06
BR9609235B1 (pt) 2009-01-13
AU5707696A (en) 1996-12-30
PT832900E (pt) 2004-07-30
CZ287816B6 (en) 2001-02-14
CN1154653C (zh) 2004-06-23
DE69631762D1 (de) 2004-04-08
JP4082522B2 (ja) 2008-04-30
LT98004A (en) 1998-10-26
CA2222296C (en) 2001-10-09
SK281825B6 (sk) 2001-08-06
BRPI9609235B8 (pt) 2016-09-27
ES2217311T3 (es) 2004-11-01
UA48974C2 (uk) 2002-09-16
HU228461B1 (en) 2013-03-28
US5736519A (en) 1998-04-07
HK1014965A1 (en) 1999-10-08

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