LU91680I2 - "rilonacept et ses dérivés pharmaceutiquement acceptables (ARCALYSR)" - Google Patents

"rilonacept et ses dérivés pharmaceutiquement acceptables (ARCALYSR)"

Info

Publication number
LU91680I2
LU91680I2 LU91680C LU91680C LU91680I2 LU 91680 I2 LU91680 I2 LU 91680I2 LU 91680 C LU91680 C LU 91680C LU 91680 C LU91680 C LU 91680C LU 91680 I2 LU91680 I2 LU 91680I2
Authority
LU
Luxembourg
Prior art keywords
arcalysr
rilonacept
pharmaceutically acceptable
acceptable derivatives
fusion polypeptide
Prior art date
Application number
LU91680C
Other languages
English (en)
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of LU91680I2 publication Critical patent/LU91680I2/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/32Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Vehicle Body Suspensions (AREA)
  • Sewing Machines And Sewing (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU91680C 2002-10-28 2010-04-21 "rilonacept et ses dérivés pharmaceutiquement acceptables (ARCALYSR)" LU91680I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/282,162 US6927044B2 (en) 1998-09-25 2002-10-28 IL-1 receptor based cytokine traps
PCT/US2003/033718 WO2004039951A2 (fr) 2002-10-28 2003-10-24 Antagonistes a base de recepteurs d'il-1 et procede de fabrication et d'utilisation

Publications (1)

Publication Number Publication Date
LU91680I2 true LU91680I2 (fr) 2010-06-21

Family

ID=32228782

Family Applications (1)

Application Number Title Priority Date Filing Date
LU91680C LU91680I2 (fr) 2002-10-28 2010-04-21 "rilonacept et ses dérivés pharmaceutiquement acceptables (ARCALYSR)"

Country Status (19)

Country Link
US (4) US6927044B2 (fr)
EP (1) EP1572967B1 (fr)
JP (1) JP4387309B2 (fr)
CN (1) CN1878871B (fr)
AT (1) ATE420970T1 (fr)
AU (1) AU2003284895B2 (fr)
BR (1) BRPI0315652B8 (fr)
CA (1) CA2502385C (fr)
CY (2) CY1110675T1 (fr)
DE (1) DE60325892D1 (fr)
DK (1) DK1572967T3 (fr)
ES (1) ES2320338T3 (fr)
HK (1) HK1080511A1 (fr)
IL (1) IL168050A (fr)
LU (1) LU91680I2 (fr)
MX (1) MXPA05004333A (fr)
PT (1) PT1572967E (fr)
SI (1) SI1572967T1 (fr)
WO (1) WO2004039951A2 (fr)

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US7927583B2 (en) 2011-04-19
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IL168050A (en) 2010-12-30
US7417134B2 (en) 2008-08-26
AU2003284895A1 (en) 2004-05-25
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CY2010010I1 (el) 2012-01-25
MXPA05004333A (es) 2005-08-03
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US20090010879A1 (en) 2009-01-08
US20050222033A1 (en) 2005-10-06
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DK1572967T3 (da) 2009-03-16
CN1878871B (zh) 2011-08-03
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PT1572967E (pt) 2009-03-05
SI1572967T1 (sl) 2009-06-30
CA2502385A1 (fr) 2004-05-13
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BRPI0315652B1 (pt) 2018-02-06
CY2010010I2 (el) 2012-01-25
AU2003284895B2 (en) 2009-11-05
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US20030143697A1 (en) 2003-07-31
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US6927044B2 (en) 2005-08-09
EP1572967A2 (fr) 2005-09-14
US20050197293A1 (en) 2005-09-08
US7361350B2 (en) 2008-04-22
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