DK3761035T3 - Analyse til bestemmelse af et proteins potentiale til selvassociering ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi - Google Patents

Analyse til bestemmelse af et proteins potentiale til selvassociering ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi Download PDF

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Publication number
DK3761035T3
DK3761035T3 DK20191942.0T DK20191942T DK3761035T3 DK 3761035 T3 DK3761035 T3 DK 3761035T3 DK 20191942 T DK20191942 T DK 20191942T DK 3761035 T3 DK3761035 T3 DK 3761035T3
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Denmark
Prior art keywords
self
protein
association
potential
analysis
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DK20191942.0T
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English (en)
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Michael Marlow
Michael Sennett
Michael Schneider
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Regeneron Pharma
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N2021/258Surface plasmon spectroscopy, e.g. micro- or nanoparticles in suspension

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK20191942.0T 2016-08-18 2017-08-18 Analyse til bestemmelse af et proteins potentiale til selvassociering ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi DK3761035T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662376788P 2016-08-18 2016-08-18
EP17761159.7A EP3500856B1 (en) 2016-08-18 2017-08-18 Assay for determining potential to self-association of a protein using concentration-dependent self-interaction nanoparticle spectroscopy

Publications (1)

Publication Number Publication Date
DK3761035T3 true DK3761035T3 (da) 2024-03-11

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DK17761159.7T DK3500856T3 (da) 2016-08-18 2017-08-18 Assay til bestemmelse af et proteins potentiale for at selvassociere ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi
DK20191942.0T DK3761035T3 (da) 2016-08-18 2017-08-18 Analyse til bestemmelse af et proteins potentiale til selvassociering ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi

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DK17761159.7T DK3500856T3 (da) 2016-08-18 2017-08-18 Assay til bestemmelse af et proteins potentiale for at selvassociere ved hjælp af koncentrationsafhængig selvinteraktionsnanopartikelspektroskopi

Country Status (18)

Country Link
US (2) US11428695B2 (da)
EP (2) EP3500856B1 (da)
JP (3) JP6959327B2 (da)
KR (3) KR102441221B1 (da)
CN (2) CN115468919A (da)
AU (2) AU2017313150B2 (da)
BR (1) BR112019003175A2 (da)
CA (1) CA3032361A1 (da)
DK (2) DK3500856T3 (da)
EA (1) EA201990316A1 (da)
ES (1) ES2837093T3 (da)
FI (1) FI3761035T3 (da)
HU (1) HUE052805T2 (da)
IL (2) IL307435A (da)
MX (1) MX2019001930A (da)
PL (1) PL3500856T3 (da)
SG (1) SG11201900895QA (da)
WO (1) WO2018035470A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2017313150B2 (en) 2016-08-18 2023-09-14 Regeneron Pharmaceuticals, Inc. Assay for determining potential to self-association of a protein using concentration-dependent self-interaction nanoparticle spectroscopy
EP3790532A1 (en) 2018-05-10 2021-03-17 Regeneron Pharmaceuticals, Inc. High concentration vegf receptor fusion protein containing formulations
CN113588582B (zh) * 2020-04-30 2024-05-14 上海药明生物技术有限公司 蛋白质样品浓度测定方式选择法及测定方法
WO2023095154A1 (en) * 2021-11-24 2023-06-01 Sensoville Biotech Pvt Ltd Method for determining changes in a protein's structure
WO2023141319A1 (en) * 2022-01-24 2023-07-27 Amgen Inc. Methods for detecting antibody self-association

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US771997A (en) 1903-11-21 1904-10-11 Alfred Palm Lathe attachment.
US4254102A (en) * 1975-09-08 1981-03-03 Plough, Inc. Substantive PABA compositions
US4080264A (en) 1976-03-01 1978-03-21 Massachusetts Institute Of Technology Immunoassay by light scattering spectroscopy
US6927044B2 (en) 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
US7087411B2 (en) 1999-06-08 2006-08-08 Regeneron Pharmaceuticals, Inc. Fusion protein capable of binding VEGF
US7514938B2 (en) 2004-05-11 2009-04-07 Board Of Regents Of The University And College System Of Nevada, On Behalf Of The University Of Nevada, Reno Dielectric relaxation spectroscopy apparatus and methods of use
TW200621282A (en) * 2004-08-13 2006-07-01 Wyeth Corp Stabilizing formulations
US20070291265A1 (en) 2006-04-13 2007-12-20 Mississippi State University Optical apparatus for simultaneously measuring the scattering and concentration of signals of macromolecules in a flow cell
CA2665423A1 (en) * 2006-10-12 2008-04-17 Wyeth Methods and compositions with reduced opalescence
ES2522615T3 (es) 2007-06-04 2014-11-17 Regeneron Pharmaceuticals, Inc. Regiones de expresión y estabilidad potenciadas
CA2700378A1 (en) * 2007-09-21 2009-03-29 Cytimmune Sciences, Inc. Nanotherapeutic colloidal metal compositions and methods
WO2010059963A2 (en) * 2008-11-21 2010-05-27 The Board Of Regents Of The University Of Texas System Preparation and methodology of silk fibroin nanoparticles
JP6099108B2 (ja) * 2013-05-30 2017-03-29 公立大学法人大阪府立大学 被検出物質の検出装置および方法
RU2675824C2 (ru) * 2013-09-11 2018-12-25 Игл Байолоджикс, Инк. Жидкие белковые составы, содержащие ионные жидкости
WO2015196091A1 (en) * 2014-06-20 2015-12-23 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
CN104062287B (zh) * 2014-07-01 2017-08-08 福建工程学院 一种基于纳米金催化的化学发光分析检测铁蛋白的方法
MA40861A (fr) 2014-10-31 2017-09-05 Biogen Ma Inc Anticorps anti-glycoprotéines iib/iiia
US20180264112A1 (en) * 2015-01-18 2018-09-20 Biogen Ma Inc. Anti-CD40 Antibody Formulations
AU2017313150B2 (en) 2016-08-18 2023-09-14 Regeneron Pharmaceuticals, Inc. Assay for determining potential to self-association of a protein using concentration-dependent self-interaction nanoparticle spectroscopy

Also Published As

Publication number Publication date
PL3500856T3 (pl) 2021-04-19
CN109661577B (zh) 2022-09-27
CN115468919A (zh) 2022-12-13
JP7321227B2 (ja) 2023-08-04
ES2837093T3 (es) 2021-06-29
MX2019001930A (es) 2019-07-04
US20220357335A1 (en) 2022-11-10
CA3032361A1 (en) 2018-02-22
WO2018035470A1 (en) 2018-02-22
IL264640A (da) 2019-04-30
JP6959327B2 (ja) 2021-11-02
IL264640B1 (en) 2023-11-01
EP3761035A1 (en) 2021-01-06
AU2017313150B2 (en) 2023-09-14
EA201990316A1 (ru) 2019-07-31
US20190187149A1 (en) 2019-06-20
IL307435A (en) 2023-12-01
EP3761035B1 (en) 2024-02-14
KR20230074614A (ko) 2023-05-30
KR20190039185A (ko) 2019-04-10
HUE052805T2 (hu) 2021-05-28
EP3500856A1 (en) 2019-06-26
JP2023139189A (ja) 2023-10-03
AU2023274236A1 (en) 2023-12-21
KR20220126801A (ko) 2022-09-16
BR112019003175A2 (pt) 2019-06-18
EP3500856B1 (en) 2020-10-07
US11428695B2 (en) 2022-08-30
JP2022008959A (ja) 2022-01-14
IL264640B2 (en) 2024-03-01
KR102534506B1 (ko) 2023-05-30
CN109661577A (zh) 2019-04-19
DK3500856T3 (da) 2020-12-14
SG11201900895QA (en) 2019-02-27
JP2019532267A (ja) 2019-11-07
WO2018035470A9 (en) 2018-07-05
AU2017313150A1 (en) 2019-02-21
US11988668B2 (en) 2024-05-21
FI3761035T3 (fi) 2024-03-18
KR102441221B1 (ko) 2022-09-07

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