DK3271724T3 - Anvendelse af en standard til påvisning af proteinaggregater i en proteinfejlfoldningssygdom - Google Patents
Anvendelse af en standard til påvisning af proteinaggregater i en proteinfejlfoldningssygdom Download PDFInfo
- Publication number
- DK3271724T3 DK3271724T3 DK16715787.4T DK16715787T DK3271724T3 DK 3271724 T3 DK3271724 T3 DK 3271724T3 DK 16715787 T DK16715787 T DK 16715787T DK 3271724 T3 DK3271724 T3 DK 3271724T3
- Authority
- DK
- Denmark
- Prior art keywords
- protein
- standard
- detection
- application
- units
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102015003404.9A DE102015003404B4 (de) | 2015-03-18 | 2015-03-18 | Verfahren zur Herstellung eines Standards für den Nachweis von Proteinaggregaten einer Proteinfehlfaltungserkrankung sowie Standard und dessen Verwendung |
| PCT/DE2016/000081 WO2016146093A1 (de) | 2015-03-18 | 2016-02-25 | Verfahren zur herstellung eines standards für den nachweis von proteinaggregaten einer proteinfehlfaltungserkrankung sowie standard und dessen verwendung - |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3271724T3 true DK3271724T3 (da) | 2020-08-10 |
Family
ID=55745499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16715787.4T DK3271724T3 (da) | 2015-03-18 | 2016-02-25 | Anvendelse af en standard til påvisning af proteinaggregater i en proteinfejlfoldningssygdom |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US10948499B2 (da) |
| EP (1) | EP3271724B1 (da) |
| JP (1) | JP6916736B2 (da) |
| CN (1) | CN107430122B (da) |
| DE (1) | DE102015003404B4 (da) |
| DK (1) | DK3271724T3 (da) |
| ES (1) | ES2810829T3 (da) |
| WO (1) | WO2016146093A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102016121455A1 (de) | 2016-11-09 | 2018-05-09 | Forschungszentrum Jülich GmbH | Ultrasensitiver Nachweis von Virus- und Virus-ähnlichen Partikeln |
| DE102017010455A1 (de) * | 2017-06-13 | 2018-12-13 | Forschungszentrum Jülich GmbH | Verfahren zum Nachweis von Aggregaten biotherapeutischer Substanzen in einer Probe |
| DE102017010842A1 (de) * | 2017-11-23 | 2019-05-23 | Forschungszentrum Jülich GmbH | Verfahren zur Quantifizierung von Proteinaggregaten einer Proteinfehlfaltungserkrankung in einer Probe |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2413884A1 (en) * | 2000-06-23 | 2002-01-03 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of protein aggregation |
| AU2001271865C1 (en) * | 2000-07-07 | 2006-12-07 | Panacea Pharmaceuticals, Inc. | Methods for preventing neural tissue damage and for the treatment of alpha-synuclein diseases |
| JP4985541B2 (ja) * | 2008-05-20 | 2012-07-25 | コニカミノルタエムジー株式会社 | ナノ粒子内包シリカ、それを用いた生体物質の標識物質および生体物質の標識方法 |
| JP5526156B2 (ja) * | 2010-02-08 | 2014-06-18 | 学校法人慈恵大学 | 磁性粒子、及びその製造方法、並びに磁性粒子含有製剤 |
| MX2012008840A (es) * | 2010-02-09 | 2012-09-07 | Squibb Bristol Myers Co | Estandares para inmunoensayos y medicion de biomarcadores clinicos usando estandares de calibracion intra-ensayos. |
| DE102011057021A1 (de) * | 2011-12-23 | 2013-06-27 | Forschungszentrum Jülich GmbH | Verfahren zur selektiven Quantifizierung von A-Beta-Aggregaten |
| DE102011057019A1 (de) | 2011-12-23 | 2013-06-27 | Forschungszentrum Jülich GmbH | Standard zur Quantifizierung von pathogenen Aggregaten aus körpereigenen Proteinen |
| WO2014056896A2 (en) * | 2012-10-08 | 2014-04-17 | Albert-Ludwigs-Universität Freiburg | One-step biomolecular immobilisation procedure and products thereof |
| DE102013106713A1 (de) * | 2013-06-26 | 2014-12-31 | Forschungszentrum Jülich GmbH | Verfahren zur Ermittlung von Indikatoren zur Bestimmung von Krankheiten |
-
2015
- 2015-03-18 DE DE102015003404.9A patent/DE102015003404B4/de active Active
-
2016
- 2016-02-25 DK DK16715787.4T patent/DK3271724T3/da active
- 2016-02-25 CN CN201680016415.5A patent/CN107430122B/zh not_active Expired - Fee Related
- 2016-02-25 ES ES16715787T patent/ES2810829T3/es active Active
- 2016-02-25 WO PCT/DE2016/000081 patent/WO2016146093A1/de active Application Filing
- 2016-02-25 EP EP16715787.4A patent/EP3271724B1/de active Active
- 2016-02-25 US US15/548,266 patent/US10948499B2/en active Active
- 2016-02-25 JP JP2017548196A patent/JP6916736B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN107430122A (zh) | 2017-12-01 |
| US20180017579A1 (en) | 2018-01-18 |
| ES2810829T3 (es) | 2021-03-09 |
| WO2016146093A1 (de) | 2016-09-22 |
| DE102015003404A1 (de) | 2016-09-22 |
| US10948499B2 (en) | 2021-03-16 |
| CN107430122B (zh) | 2019-10-11 |
| EP3271724A1 (de) | 2018-01-24 |
| DE102015003404B4 (de) | 2021-10-07 |
| JP2018514754A (ja) | 2018-06-07 |
| EP3271724B1 (de) | 2020-05-27 |
| JP6916736B2 (ja) | 2021-08-11 |
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