BR112017002622A2 - métodos e sistemas para quantificação seletiva e detecção de alergênicos - Google Patents

métodos e sistemas para quantificação seletiva e detecção de alergênicos

Info

Publication number
BR112017002622A2
BR112017002622A2 BR112017002622A BR112017002622A BR112017002622A2 BR 112017002622 A2 BR112017002622 A2 BR 112017002622A2 BR 112017002622 A BR112017002622 A BR 112017002622A BR 112017002622 A BR112017002622 A BR 112017002622A BR 112017002622 A2 BR112017002622 A2 BR 112017002622A2
Authority
BR
Brazil
Prior art keywords
systems
methods
signature peptides
allergen detection
selective quantification
Prior art date
Application number
BR112017002622A
Other languages
English (en)
Inventor
William Schafer Barry
Shan Guomin
Christopher Hill Ryan
James Oman Trent
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of BR112017002622A2 publication Critical patent/BR112017002622A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/24—Immunology or allergic disorders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers

Abstract

a presente invenção refere-se aos métodos e sistemas que tiram vantagem de investigações bioinformáticas para identificar os peptídeos de assinatura candidatos para a analise multiplex quantitativa de amostras de proteínas complexas a partir de plantas, partes de plantas e/ou produtos alimentares utilizando espectroscopia de massa. é proporcionado o uso e métodos para selecionar os peptídeos de assinatura candidatos para quantificação usando uma abordagem bioinformática. são também proporcionados sistemas que compreendem uma cromatografia e espectrometria de massa para utilização de peptídeos de assinatura selecionados.
BR112017002622A 2014-08-11 2015-08-11 métodos e sistemas para quantificação seletiva e detecção de alergênicos BR112017002622A2 (pt)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201462035731P 2014-08-11 2014-08-11
US201462035920P 2014-08-11 2014-08-11
US201462035744P 2014-08-11 2014-08-11
US201462035800P 2014-08-11 2014-08-11
US201462035944P 2014-08-11 2014-08-11
US201462035858P 2014-08-11 2014-08-11
US201462035876P 2014-08-11 2014-08-11
US201462035768P 2014-08-11 2014-08-11
US201462036926P 2014-08-13 2014-08-13
PCT/US2015/044710 WO2016025516A1 (en) 2014-08-11 2015-08-11 Methods and systems for selective quantitation and detection of allergens

Publications (1)

Publication Number Publication Date
BR112017002622A2 true BR112017002622A2 (pt) 2018-02-20

Family

ID=55304559

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017002622A BR112017002622A2 (pt) 2014-08-11 2015-08-11 métodos e sistemas para quantificação seletiva e detecção de alergênicos

Country Status (6)

Country Link
EP (1) EP3180622A4 (pt)
CN (1) CN106796242A (pt)
AU (1) AU2015301806A1 (pt)
BR (1) BR112017002622A2 (pt)
CA (1) CA2958063A1 (pt)
WO (1) WO2016025516A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018140370A1 (en) * 2017-01-25 2018-08-02 Dow Agrosciences Llc Methods and systems for selective quantitation and detection of allergens including gly m 7
CN110862996B (zh) * 2019-12-23 2020-12-25 华中农业大学 一段分离的大豆基因在提高大豆孢囊线虫抗性中的应用
CN111187343B (zh) * 2020-03-16 2022-02-25 西北大学 一种牡丹类2s白蛋白及其提取方法和应用
CN113429474B (zh) * 2021-07-07 2022-08-05 天津中医药大学 一种基于特征性肽段标签鉴别植物蛋白肉样品掺假情况的方法
CN114990181B (zh) * 2022-05-13 2023-08-22 中食都庆（山东）生物技术有限公司 一种抗衰老的大豆肽及其制备方法和应用
CN116491631A (zh) * 2023-05-26 2023-07-28 青岛农业大学 一种预制菜红烧肉及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009508118A (ja) * 2005-09-15 2009-02-26 アルク−アベッロ エイ／エス アレルゲンの定量方法
PT1931998E (pt) * 2005-09-15 2010-09-13 Alk Abello As Método de quantificação de alergénios
US8835361B2 (en) * 2010-06-01 2014-09-16 The Curators Of The University Of Missouri High-throughput quantitation of crop seed proteins
CN106461610A (zh) * 2014-06-10 2017-02-22 美国陶氏益农公司 转基因蛋白的定量分析

Also Published As

Publication number Publication date
EP3180622A4 (en) 2018-02-28
WO2016025516A1 (en) 2016-02-18
CA2958063A1 (en) 2016-02-18
CN106796242A (zh) 2017-05-31
AU2015301806A1 (en) 2017-03-02
EP3180622A1 (en) 2017-06-21

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired
B350 Update of information on the portal [chapter 15.35 patent gazette]