ITUB20160829A1 - Fissativo per preparati istologici comprendente gliossale privo di acidi - Google Patents

Fissativo per preparati istologici comprendente gliossale privo di acidi

Info

Publication number
ITUB20160829A1
ITUB20160829A1 ITUB2016A000829A ITUB20160829A ITUB20160829A1 IT UB20160829 A1 ITUB20160829 A1 IT UB20160829A1 IT UB2016A000829 A ITUB2016A000829 A IT UB2016A000829A IT UB20160829 A ITUB20160829 A IT UB20160829A IT UB20160829 A1 ITUB20160829 A1 IT UB20160829A1
Authority
IT
Italy
Prior art keywords
gliossal
aclixy
fixative
preparations including
histological preparations
Prior art date
Application number
ITUB2016A000829A
Other languages
English (en)
Inventor
Giovanni Bussolati
Original Assignee
Addax Biosciences S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Addax Biosciences S R L filed Critical Addax Biosciences S R L
Priority to ITUB2016A000829A priority Critical patent/ITUB20160829A1/it
Priority to EP17706968.9A priority patent/EP3416482B1/en
Priority to ES17706968T priority patent/ES2847831T3/es
Priority to JP2018543152A priority patent/JP6947410B2/ja
Priority to PCT/EP2017/053041 priority patent/WO2017140596A1/en
Priority to US16/075,149 priority patent/US11204305B2/en
Priority to CN201780010590.8A priority patent/CN108601340B/zh
Priority to CA3014243A priority patent/CA3014243A1/en
Publication of ITUB20160829A1 publication Critical patent/ITUB20160829A1/it

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/0231—Chemically defined matrices, e.g. alginate gels, for immobilising, holding or storing cells, tissue or organs for preservation purposes; Chemically altering or fixing cells, tissue or organs, e.g. by cross-linking, for preservation purposes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G01N2001/307—Fixative compositions non-toxic, no Hg, no formaldehyde

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
ITUB2016A000829A 2016-02-18 2016-02-18 Fissativo per preparati istologici comprendente gliossale privo di acidi ITUB20160829A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITUB2016A000829A ITUB20160829A1 (it) 2016-02-18 2016-02-18 Fissativo per preparati istologici comprendente gliossale privo di acidi
EP17706968.9A EP3416482B1 (en) 2016-02-18 2017-02-10 Acid free glyoxal as fixative for histological preparations
ES17706968T ES2847831T3 (es) 2016-02-18 2017-02-10 Glioxal libre de ácido como fijador para preparaciones histológicas
JP2018543152A JP6947410B2 (ja) 2016-02-18 2017-02-10 組織標本用固定剤としての無酸グリオキサール
PCT/EP2017/053041 WO2017140596A1 (en) 2016-02-18 2017-02-10 Acid free glyoxal as fixative for histological preparations
US16/075,149 US11204305B2 (en) 2016-02-18 2017-02-10 Acid free glyoxal as fixative for histological preparations
CN201780010590.8A CN108601340B (zh) 2016-02-18 2017-02-10 作为用于组织学制品的固定剂的无酸乙二醛
CA3014243A CA3014243A1 (en) 2016-02-18 2017-02-10 Acid free glyoxal as fixative for histological preparations

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITUB2016A000829A ITUB20160829A1 (it) 2016-02-18 2016-02-18 Fissativo per preparati istologici comprendente gliossale privo di acidi

Publications (1)

Publication Number Publication Date
ITUB20160829A1 true ITUB20160829A1 (it) 2017-08-18

Family

ID=56097194

Family Applications (1)

Application Number Title Priority Date Filing Date
ITUB2016A000829A ITUB20160829A1 (it) 2016-02-18 2016-02-18 Fissativo per preparati istologici comprendente gliossale privo di acidi

Country Status (8)

Country Link
US (1) US11204305B2 (it)
EP (1) EP3416482B1 (it)
JP (1) JP6947410B2 (it)
CN (1) CN108601340B (it)
CA (1) CA3014243A1 (it)
ES (1) ES2847831T3 (it)
IT (1) ITUB20160829A1 (it)
WO (1) WO2017140596A1 (it)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10501891B1 (en) * 2019-01-25 2019-12-10 Rayonier Performance Fibers, L.L.C. Crosslinking cellulose with Glyoxal to improve absorption properties
JP2021075506A (ja) * 2019-11-13 2021-05-20 学校法人北里研究所 耐変色標本固定剤及びその使用
IT201900024448A1 (it) * 2019-12-18 2021-06-18 Addax Biosciences S R L Conservazione di sequenze di acidi nucleici mediante fissazione dei tessuti in formalina tamponata preparata utilizzando formaldeide deprivata di acidi

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2159975A1 (de) * 1971-12-03 1973-06-07 Veba Chemie Ag Glyoxalhalbacetale, verfahren zu ihrer herstellung und ihre verwendung
US5998483A (en) * 1991-09-20 1999-12-07 Camiener; Gerald W. Glyoxal-containing preservative compositions
EP0627879A1 (en) * 1991-09-20 1994-12-14 CAMIENER, Gerald, W. Methods and compositions with aldehyde stabilizing solution
JP5614913B2 (ja) * 2002-07-16 2014-10-29 ピラマル ヘルスケア （カナダ） リミテッド 生細胞又は生物学的活性因子を封入し送達するための、細胞適合性、注射可能、かつ自己ゲル化性のキトサン溶液の組成物
US20050181353A1 (en) * 2004-02-17 2005-08-18 Rao Galla C. Stabilization of cells and biological specimens for analysis
US7368132B2 (en) * 2004-10-27 2008-05-06 Medical Chemical Corporation Glyoxal/zinc fixative
EP2388567A1 (en) * 2005-03-28 2011-11-23 Medimex Co., Ltd. Supporting solution for cytological diagnosis
FR2926814B1 (fr) * 2008-01-25 2012-08-03 Clariant Specialty Fine Chem F Procede de preparation d'une solution aqueuse d'acide glyoxylique.
FR2933271B1 (fr) * 2008-07-01 2010-07-30 Arkema France Compositions topiques pour la conservation du corps humain ou animal
CN101473812B (zh) * 2009-01-24 2011-09-14 温州医学院 一种用于尸体标本的防腐固定液组合物及其制备方法
FR2943889B1 (fr) * 2009-04-07 2011-04-29 Arkema France Compositions pour la conservation du corps humain ou animal.
CN104365579A (zh) * 2013-08-13 2015-02-25 陆伟明 一种标本耐固防腐定型液
US9733162B2 (en) * 2014-02-11 2017-08-15 Ihor Turkevych Universal system, method and solution for the acceleration of the process of fixing, dehydrating and clearing the structure of biological tissue
JP6908531B2 (ja) * 2015-01-27 2021-07-28 ベンタナ メディカル システムズ， インコーポレイテッド アルデヒドに基づく固定溶液における長時間浸漬を用いる、組織試料固定法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
D. D. SABATINI ET AL: "CYTOCHEMISTRY AND ELECTRON MICROSCOPY: The Preservation of Cellular Ultrastructure and Enzymatic Activity by Aldehyde Fixation", THE JOURNAL OF CELL BIOLOGY : JCB, vol. 17, no. 1, 1 April 1963 (1963-04-01), US, pages 19 - 58, XP055283416, ISSN: 0021-9525, DOI: 10.1083/jcb.17.1.19 *
NATHALIE GEHIN: "Le glyoxal: un possible substitut du formaldehyde en anatomie pathologique? - Thèse doctorale", 13 June 2008 (2008-06-13), Nancy (France), pages 1 - 207, XP055283404, Retrieved from the Internet <URL:http://docnum.univ-lorraine.fr/public/SCDMED_T_2008_GEHIN_MARCON_NATHALIE.pdf> [retrieved on 20160624] *
RW DAPSON: "Glyoxal fixation: how it works and why it only occasionally needs antigen retrieval", BIOTECHNIC AND HISTOCHEMISTRY., vol. 82, no. 3, 1 January 2007 (2007-01-01), US, pages 161 - 166, XP055283259, ISSN: 1052-0295, DOI: 10.1080/10520290701488113 *
YN WANG ET AL: "Histomorphometric comparison after fixation with formaldehyde or glyoxal", BIOTECHNIC AND HISTOCHEMISTRY., vol. 86, no. 5, 21 September 2010 (2010-09-21), US, pages 359 - 365, XP055283253, ISSN: 1052-0295, DOI: 10.3109/10520295.2010.520275 *

Also Published As

Publication number Publication date
ES2847831T3 (es) 2021-08-04
JP2019507342A (ja) 2019-03-14
WO2017140596A1 (en) 2017-08-24
JP6947410B2 (ja) 2021-10-13
US11204305B2 (en) 2021-12-21
CN108601340B (zh) 2022-03-22
EP3416482A1 (en) 2018-12-26
US20190049348A1 (en) 2019-02-14
CA3014243A1 (en) 2017-08-24
EP3416482B1 (en) 2020-12-30
CN108601340A (zh) 2018-09-28

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