LU58316A1 - - Google Patents

Info

Publication number
LU58316A1
LU58316A1 LU58316DA LU58316A1 LU 58316 A1 LU58316 A1 LU 58316A1 LU 58316D A LU58316D A LU 58316DA LU 58316 A1 LU58316 A1 LU 58316A1
Authority
LU
Luxembourg
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of LU58316A1 publication Critical patent/LU58316A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LU58316D 1968-04-03 1969-03-26 LU58316A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB06113/68A GB1218591A (en) 1968-04-03 1968-04-03 Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation

Publications (1)

Publication Number Publication Date
LU58316A1 true LU58316A1 (es) 1969-10-27

Family

ID=10071423

Family Applications (1)

Application Number Title Priority Date Filing Date
LU58316D LU58316A1 (es) 1968-04-03 1969-03-26

Country Status (17)

Country Link
US (1) US3634411A (es)
BE (1) BE730345A (es)
BG (1) BG15397A3 (es)
CH (1) CH498845A (es)
CS (1) CS163733B2 (es)
DK (1) DK123824C (es)
FI (1) FI51190C (es)
FR (1) FR2007372A1 (es)
GB (1) GB1218591A (es)
IL (1) IL31901A (es)
IT (1) IT1036019B (es)
LU (1) LU58316A1 (es)
NL (1) NL147427B (es)
NO (1) NO124312B (es)
RO (1) RO55704A (es)
SE (1) SE351212B (es)
YU (1) YU33015B (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2516510A1 (fr) * 1981-11-19 1983-05-20 Hokuriku Pharmaceutical Derives de la (trimethoxy-3,4,5-cinnamoyl)-1-aminocarbonylethyl-4-piperazine substituee utilisables en pharmacie et procede pour leur preparation
EP0175331A1 (en) * 1984-09-17 1986-03-26 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Piperazine Derivatives

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092703A1 (en) * 1970-06-10 1972-01-28 Delalande Sa 2-(1-pyrrolidinocarbonylmethyl-piperazin-4-yl) ethyl - 3,4,5-trimethoxy benzoate - having hypotensive and adrenolytic active
FR2092902A1 (en) * 1970-06-30 1972-01-28 Delalande Sa Substd propiophenone - beta (pyrrolidino carbonylmethyl)-1'-piperazin propiophenones, analgesics, hypotensives adrenolytics, noradrenolytic
FR2278340A1 (fr) * 1974-07-17 1976-02-13 Delalande Sa Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique
GB1473262A (en) * 1974-11-20 1977-05-11 Delalande Sa Derivatives of n-3,4,5-trimethoxy cinnamoyl-piperazine their process of preparation and their therapeutic application
GR71991B (es) * 1980-01-21 1983-08-26 Delalande Sa
IT1151104B (it) * 1982-02-04 1986-12-17 Delalande Sa Impiego terapeutico di derivati (1-cinnamoil oppure 1-fenetil-carbonil)piperazinici
FR2522325B1 (fr) * 1982-02-26 1985-08-09 Delalande Sa Nouveaux derives aryliques de la piperazine, de l'homopiperazine et de n,n'-dialkyl diamino-1,2 ethane, leur procede de preparation et leur application en therapeutique
FR2552762B1 (fr) * 1983-09-30 1986-07-25 Delalande Sa Nouveaux amides piperaziniques et homopiperaziniques derives de l'acide 3,4-dioxymethylene cinnamique, leur procede de preparation et leur application en therapeutique
US6011035A (en) * 1998-06-30 2000-01-04 Neuromed Technologies Inc. Calcium channel blockers
AP2005003232A0 (en) 2002-08-19 2005-03-31 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US8383660B2 (en) 2006-03-10 2013-02-26 Pfizer Inc. Dibenzyl amine compounds and derivatives
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
AU2008277796A1 (en) * 2007-07-19 2009-01-22 F. Hoffmann-La Roche Ag Novel heterocyclyl compounds and their use as chemokine antagonists
CN101260092B (zh) * 2008-04-14 2011-07-20 罗军 马来酸桂哌齐特的制备方法
CN101723918B (zh) * 2008-10-24 2011-08-31 重庆医科大学医药研究所 马来酸桂哌齐特的制备工艺
CN101531643B (zh) * 2009-04-13 2012-11-14 上海理奥生物医药科技有限责任公司 一种改进的马来酸桂哌齐特的合成方法
CN102229583B (zh) * 2011-05-13 2013-11-27 江苏神龙药业有限公司 一种桂哌齐特的合成方法
CN103664830A (zh) * 2012-09-05 2014-03-26 凌沛学 一种马来酸桂哌齐特改进的合成方法
CN103896878B (zh) * 2012-12-26 2018-02-09 江苏万邦生化医药股份有限公司 一种桂哌齐特的纯化脱色方法
CN103245734A (zh) * 2013-01-18 2013-08-14 沈阳亿灵医药科技有限公司 一组控制马来酸桂哌齐特质量的组合物
CN105143203A (zh) 2013-04-17 2015-12-09 辉瑞大药厂 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
WO2020150473A2 (en) 2019-01-18 2020-07-23 Dogma Therapeutics, Inc. Pcsk9 inhibitors and methods of use thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2516510A1 (fr) * 1981-11-19 1983-05-20 Hokuriku Pharmaceutical Derives de la (trimethoxy-3,4,5-cinnamoyl)-1-aminocarbonylethyl-4-piperazine substituee utilisables en pharmacie et procede pour leur preparation
EP0083712A1 (en) * 1981-11-19 1983-07-20 Hokuriku Pharmaceutical Co.,Ltd 1-(3,4,5-Trimethoxycinnamoyl)-4-aminocarbonylethyl-substituted piperazine derivatives and a process for the preparation thereof
EP0175331A1 (en) * 1984-09-17 1986-03-26 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Piperazine Derivatives

Also Published As

Publication number Publication date
FR2007372A1 (es) 1970-01-09
BG15397A3 (bg) 1976-05-26
IL31901A (en) 1972-03-28
IT1036019B (it) 1979-10-30
GB1218591A (en) 1971-01-06
US3634411A (en) 1972-01-11
DK123824B (es) 1972-08-07
CS163733B2 (es) 1975-11-07
SE351212B (es) 1972-11-20
RO55704A (es) 1974-01-03
NL147427B (nl) 1975-10-15
NL6905019A (es) 1969-10-07
CH498845A (fr) 1970-11-15
YU33015B (en) 1976-03-31
BE730345A (es) 1969-09-21
YU83469A (en) 1975-06-30
FI51190C (fi) 1976-11-10
DE1915795B2 (de) 1975-07-03
DK123824C (da) 1972-12-18
NO124312B (es) 1972-04-04
DE1915795A1 (de) 1970-09-10
FI51190B (es) 1976-08-02
IL31901A0 (en) 1969-05-28

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