FR2278340A1 - Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique - Google Patents

Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique

Info

Publication number
FR2278340A1
FR2278340A1 FR7424831A FR7424831A FR2278340A1 FR 2278340 A1 FR2278340 A1 FR 2278340A1 FR 7424831 A FR7424831 A FR 7424831A FR 7424831 A FR7424831 A FR 7424831A FR 2278340 A1 FR2278340 A1 FR 2278340A1
Authority
FR
France
Prior art keywords
cinnamoyl
trimethoxy
piperazine
preparation process
therapeutic application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7424831A
Other languages
English (en)
Other versions
FR2278340B1 (fr
Inventor
Michel Turin
Patrick Guerret
Guy Raynaud
Bernard Pourrias
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7424831A priority Critical patent/FR2278340A1/fr
Priority to GB2750275A priority patent/GB1452878A/en
Priority to BE157877A priority patent/BE830874A/fr
Priority to ZA00754268A priority patent/ZA754268B/xx
Priority to ES439291A priority patent/ES439291A1/es
Priority to JP50086608A priority patent/JPS5134177A/ja
Priority to LU72983A priority patent/LU72983A1/xx
Priority to US05/596,041 priority patent/US4016154A/en
Priority to IT68867/75A priority patent/IT1044530B/it
Priority to CH933175A priority patent/CH593966A5/xx
Priority to AU83080/75A priority patent/AU488027B2/en
Priority to DE2531829A priority patent/DE2531829C2/de
Priority to SE7508153A priority patent/SE417428B/xx
Priority to SU7502152022A priority patent/SU569289A3/ru
Priority to NL7508530A priority patent/NL7508530A/xx
Priority to CA231,613A priority patent/CA1030538A/fr
Publication of FR2278340A1 publication Critical patent/FR2278340A1/fr
Application granted granted Critical
Publication of FR2278340B1 publication Critical patent/FR2278340B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
FR7424831A 1974-07-17 1974-07-17 Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique Granted FR2278340A1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR7424831A FR2278340A1 (fr) 1974-07-17 1974-07-17 Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique
GB2750275A GB1452878A (en) 1974-07-17 1975-06-30 Derivative of n- 3,4,5-trimethoxy cinnamoyl- piperazine its acid addition salts is process of preparation and its therapeutic app lication
BE157877A BE830874A (fr) 1974-07-17 1975-07-01 Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl)piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique
ZA00754268A ZA754268B (en) 1974-07-17 1975-07-03 A novel derivative of n-(3,4,5-trimethoxy cinnamoyl) piperazine, its acid addition salts, its process of preparation and its therapeutic application
ES439291A ES439291A1 (es) 1974-07-17 1975-07-10 Procedimiento de preparacion de la n-trimetoxi-3, 4, 5-cina-moil)-n'-(pirrolidinona-2'-carbonilmetil-1')-piperazina.
LU72983A LU72983A1 (fr) 1974-07-17 1975-07-15
US05/596,041 US4016154A (en) 1974-07-17 1975-07-15 Novel derivative of N-(3,4,5-trimethoxy cinnamoyl) piperazine, its acid addition salts, its process of preparation and its therapeutic application
JP50086608A JPS5134177A (en) 1974-07-17 1975-07-15 Nn * 3 4 55 torimetokishishinnamoiru * piperajinruinoseiho
IT68867/75A IT1044530B (it) 1974-07-17 1975-07-16 Derivato della n..trime tossi 3..4..5 cinnamoil..piperazina..suoi sali d addizione di acidi suo procedimento di prepparazione e sua applicazione in terapeutica
CH933175A CH593966A5 (fr) 1974-07-17 1975-07-16
AU83080/75A AU488027B2 (en) 1974-07-17 1975-07-16 Anovel derivative of n-(3, 4, 5-trimethoxy cinnamoyl) piperazine, its acid addition salts, its process of preparation and its therapeutic application
DE2531829A DE2531829C2 (de) 1974-07-17 1975-07-16 N-(3,4,5-Trimethoxycinnamoyl)-N'- (2'-pyrrolidinon-1'-carbonylmethyl) -piperazin, Verfahren zu dessen Herstellung und diese Verbindung enthaltende Arzneimittel
SE7508153A SE417428B (sv) 1974-07-17 1975-07-16 Sett att framstella n-(3,4,5-trimetoxi-cinnamoyl)-piperazin och dess syraadditionssalter
SU7502152022A SU569289A3 (ru) 1974-07-17 1975-07-16 Способ получени -(3,4,5-триметоксициннамоил)- -(пирролидинон-2-ил1-карбонилметил) пиперазина или его солей
NL7508530A NL7508530A (nl) 1974-07-17 1975-07-16 Werkwijze voor de bereiding van een nieuwe n-(3,4,5-trimethoxy-cinnamoyl)piperazinever- binding en de zuuradditiezouten daarvan.
CA231,613A CA1030538A (fr) 1974-07-17 1975-07-16 Derive de la n-(trimethoxy-3,4,5 cynnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7424831A FR2278340A1 (fr) 1974-07-17 1974-07-17 Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique

Publications (2)

Publication Number Publication Date
FR2278340A1 true FR2278340A1 (fr) 1976-02-13
FR2278340B1 FR2278340B1 (fr) 1978-07-21

Family

ID=9141387

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7424831A Granted FR2278340A1 (fr) 1974-07-17 1974-07-17 Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique

Country Status (15)

Country Link
US (1) US4016154A (fr)
JP (1) JPS5134177A (fr)
BE (1) BE830874A (fr)
CA (1) CA1030538A (fr)
CH (1) CH593966A5 (fr)
DE (1) DE2531829C2 (fr)
ES (1) ES439291A1 (fr)
FR (1) FR2278340A1 (fr)
GB (1) GB1452878A (fr)
IT (1) IT1044530B (fr)
LU (1) LU72983A1 (fr)
NL (1) NL7508530A (fr)
SE (1) SE417428B (fr)
SU (1) SU569289A3 (fr)
ZA (1) ZA754268B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2460942A1 (fr) * 1979-07-12 1981-01-30 Delalande Sa Nouveaux derives de l'acide a-amino butyrique, leur procede de preparation et leur application en therapeutique

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique
GR71991B (fr) * 1980-01-21 1983-08-26 Delalande Sa
JPS5888370A (ja) * 1981-11-19 1983-05-26 Hokuriku Seiyaku Co Ltd １−（３，４，５−トリメトキシシンナモイル）−４−アミノカルボニルエチル置換ピペラジン及びホモピペラジン誘導体、及びその製造方法
ES8302692A1 (es) * 1982-03-24 1983-02-01 Prodes Sa "procedimiento para la obtencion de n-(2-oxo-1-pirrolidinil)acetil piperazinas sustituidas".
FR2552762B1 (fr) * 1983-09-30 1986-07-25 Delalande Sa Nouveaux amides piperaziniques et homopiperaziniques derives de l'acide 3,4-dioxymethylene cinnamique, leur procede de preparation et leur application en therapeutique

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1218591A (en) * 1968-04-03 1971-01-06 Delalande Sa Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation
BE754640A (fr) * 1969-08-11 1971-02-10 Geigy Ag J R Derives de l'imidazolidinone et medicaments contenant de tels derives
BE754642A (fr) * 1969-08-11 1971-02-10 Geigy Ag J R Derives de l'imidazolidinone et medicaments contenant de tels derives
GB1391007A (en) * 1971-06-17 1975-04-16 Ciba Geigy Ag Imidazolidinone derivatives and processes for the production thereof
US3784545A (en) * 1972-05-31 1974-01-08 Abbott Lab 1-(5-phenyl-4-oxo-2-oxazolin-2-yl)-4-cinnamoylpiperazines
US3806510A (en) * 1972-09-18 1974-04-23 Parke Davis & Co 4(orthoalkylthio phenyl)piperazin-1-yl hydantoins

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2460942A1 (fr) * 1979-07-12 1981-01-30 Delalande Sa Nouveaux derives de l'acide a-amino butyrique, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
SE7508153L (sv) 1976-01-19
ZA754268B (en) 1976-06-30
NL7508530A (nl) 1976-01-20
BE830874A (fr) 1976-01-02
DE2531829A1 (de) 1976-02-05
GB1452878A (en) 1976-10-20
IT1044530B (it) 1980-03-31
CA1030538A (fr) 1978-05-02
JPS5134177A (en) 1976-03-23
LU72983A1 (fr) 1976-05-31
DE2531829C2 (de) 1985-12-12
JPS61337B2 (fr) 1986-01-08
CH593966A5 (fr) 1977-12-30
AU8308075A (en) 1977-01-20
SE417428B (sv) 1981-03-16
ES439291A1 (es) 1977-02-16
US4016154A (en) 1977-04-05
FR2278340B1 (fr) 1978-07-21
SU569289A3 (ru) 1977-08-15

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