BE835224A - Nouveaux derives piperidylideniques, leur procede de preparation et leur usage therapeutique - Google Patents

Nouveaux derives piperidylideniques, leur procede de preparation et leur usage therapeutique

Info

Publication number
BE835224A
BE835224A BE161500A BE161560A BE835224A BE 835224 A BE835224 A BE 835224A BE 161500 A BE161500 A BE 161500A BE 161560 A BE161560 A BE 161560A BE 835224 A BE835224 A BE 835224A
Authority
BE
Belgium
Prior art keywords
piperidylidenic
derivatives
preparation
new
therapeutic use
Prior art date
Application number
BE161500A
Other languages
English (en)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE835224A publication Critical patent/BE835224A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE161500A 1974-11-06 1975-11-04 Nouveaux derives piperidylideniques, leur procede de preparation et leur usage therapeutique BE835224A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52121674A 1974-11-06 1974-11-06

Publications (1)

Publication Number Publication Date
BE835224A true BE835224A (fr) 1976-05-04

Family

ID=24075868

Family Applications (1)

Application Number Title Priority Date Filing Date
BE161500A BE835224A (fr) 1974-11-06 1975-11-04 Nouveaux derives piperidylideniques, leur procede de preparation et leur usage therapeutique

Country Status (17)

Country Link
JP (1) JPS5826754B2 (fr)
AU (1) AU498298B2 (fr)
BE (1) BE835224A (fr)
CA (1) CA1055945A (fr)
CH (1) CH624403A5 (fr)
DE (1) DE2549841A1 (fr)
DK (1) DK139429B (fr)
ES (1) ES442357A1 (fr)
FR (1) FR2290202A1 (fr)
HU (1) HU174639B (fr)
IE (1) IE42137B1 (fr)
IL (1) IL48400A (fr)
LU (1) LU73714A1 (fr)
NL (1) NL7512974A (fr)
NZ (1) NZ179139A (fr)
PH (1) PH12158A (fr)
ZA (1) ZA756550B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002902A1 (fr) * 1977-12-29 1979-07-11 Kefalas A/S Dérivé de thioxanthène méthylthiofluoro-substitué, sa préparation et compositions le contenant

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2357251A1 (fr) * 1976-07-09 1978-02-03 Merck & Co Inc 1-methyl-4-(2-carboxy-1-thioxanthan-9-ylidene)-piperidine
US4073912A (en) * 1976-10-12 1978-02-14 Smithkline Corporation Piperidylidene derivatives of benzo-fused xanthenes, thioxanthenes and dibenzoxepins and antipsychotic use thereof
US4089961A (en) * 1976-11-08 1978-05-16 Smithkline Corporation Antipsychotically useful quinolizidylidene derivatives of xanthenes, thioxanthenes and dibenzoxepins
US4777177A (en) * 1984-10-19 1988-10-11 Ciba-Geigy Corporation Pesticidal thioxanthen-9-ylidenepiperidines
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
CA2004211A1 (fr) * 1988-11-30 1990-05-31 Masataka Syoji Derives de piperidine et hypotenseurs les contenant
EP1306376A1 (fr) * 2001-10-25 2003-05-02 Biofrontera Pharmaceuticals AG Dérives de 4-(thio- or selenoxanthene-9-ylidene)-piperidine ou acridine et leur application comme antagonistes selectives de 5-HT2B
US7060711B2 (en) 2001-10-25 2006-06-13 Biofrontera Bioscience Gmbh Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist
EA015491B1 (ru) * 2003-06-27 2011-08-30 Янссен Фармацевтика Н.В. ТРИЦИКЛИЧЕСКИЕ δ-ОПИОИДНЫЕ МОДУЛЯТОРЫ
KR20080027216A (ko) 2004-08-05 2008-03-26 얀센 파마슈티카 엔.브이. 트리사이클릭 δ-오피오이드 조절자
EP1836196A1 (fr) * 2004-12-22 2007-09-26 Janssen Pharmaceutica N.V. Modulateurs des recepteurs opioides delta tricycliques
CA2591963A1 (fr) 2004-12-22 2006-06-29 Janssen Pharmaceutica N.V. Modulateurs des recepteurs opioides $g(d) tricycliques
KR20070087675A (ko) 2004-12-22 2007-08-28 얀센 파마슈티카 엔.브이. 트리사이클릭 δ-오피오이드 모듈레이터
AU2006203880A1 (en) 2005-01-06 2006-07-13 Janssen Pharmaceutica N.V. Tricyclic delta-opioid modulators
WO2006138528A2 (fr) 2005-06-16 2006-12-28 Janssen Pharmaceutica N.V Modulateurs d'opioides tricycliques
AU2007301145B2 (en) 2006-09-29 2012-12-13 Nippon Zoki Pharmaceutical Co., Ltd. Oxepin derivative

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL260070A (fr) * 1960-02-25
NL122808C (fr) * 1961-09-29
DE1670118A1 (de) * 1966-07-22 1970-11-05 Boehringer Mannheim Gmbh Verfahren zur Herstellung neuer Derivate des 6,11-Dihydro-dibenz[b,e]oxepins und ihrer Salze
US3470188A (en) * 1967-01-05 1969-09-30 Smithkline Corp 9-cycloalkyl-lower alkyl-piperidylidene derivatives of xanthenes and thioxanthenes
JPS5018478A (fr) * 1973-05-17 1975-02-26

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002902A1 (fr) * 1977-12-29 1979-07-11 Kefalas A/S Dérivé de thioxanthène méthylthiofluoro-substitué, sa préparation et compositions le contenant
US4235916A (en) * 1977-12-29 1980-11-25 Kefalas A/S 2-Methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene and salts thereof, neuroleptic compositions and method of use

Also Published As

Publication number Publication date
DK495775A (fr) 1976-05-07
IE42137B1 (en) 1980-06-04
JPS5826754B2 (ja) 1983-06-04
DE2549841A1 (de) 1976-05-13
HU174639B (hu) 1980-02-28
FR2290202B1 (fr) 1980-05-23
IE42137L (en) 1976-05-06
DK139429C (fr) 1979-08-06
IL48400A0 (en) 1976-01-30
AU8624775A (en) 1977-05-05
DE2549841C2 (fr) 1988-07-07
AU498298B2 (en) 1979-03-01
IL48400A (en) 1979-01-31
ES442357A1 (es) 1977-04-01
NL7512974A (nl) 1976-05-10
JPS5170768A (fr) 1976-06-18
LU73714A1 (fr) 1976-06-11
NZ179139A (en) 1978-04-28
PH12158A (en) 1978-11-10
ZA756550B (en) 1976-09-29
DK139429B (da) 1979-02-19
CA1055945A (fr) 1979-06-05
CH624403A5 (en) 1981-07-31
FR2290202A1 (fr) 1976-06-04

Similar Documents

Publication Publication Date Title
BE865632A (fr) Nouveaux derives de cephalosporine, leur procede de preparation et leur application en therapeutique
FR2274289A1 (fr) Nouveaux derives d'acide oxy-16 prostanoique, leur procede de preparation et leur utilisation therapeutique
FR2320295A1 (fr) Nouveaux derives de la 2,3-dioxopiperazine et leur procede de preparation
BE789629A (fr) Nouveaux derives de la pleuromutiline, leur preparation et leurapplication en therapeutique
BE842310A (fr) Derives de la thieno-pyridine, leur procede de preparation et composition therapeutique les contenant
BE881134A (fr) Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
BE835224A (fr) Nouveaux derives piperidylideniques, leur procede de preparation et leur usage therapeutique
BE822616A (fr) Derives de 7alpha-methoxycephalosporine leur procede de preparation et leur application therapeutique
LU76848A1 (fr) Nouveaux hydroxymethyl-5 oxazolidinone-2, leur procede de preparation et leur application therapeutique
BE824697A (fr) Derives de benzylamine et leur procede de preparation
FR2315925A1 (fr) Nouveaux derives de 5-benzyle-2-oxazolidone, leur procede de preparation et leur application en therapeutique
BE883124A (fr) Nouveaux derives de la 5h-furanone-2 et de la 3h-dihydro-furanone-2, leur procede de preparation et leur application en therapeutique
FR2313063A1 (fr) Derives de pyrrolotriazolopyrimidine leur procede de preparation et leurs applications en therapeutique
LU79606A1 (fr) Derives de bisamidine,leur procede de preparation et leur application therapeutique
BE832128A (fr) Derives antibiotiques de xk-62-2, leur procede de preparation et leur utilisation therapeutique
FR2290207A1 (fr) Nouveaux derives de 3,4-dihydrocarbostyril et leur procede de preparation
FR2352783A1 (fr) Derives polyprenyl-carboxyliques, leur procede de preparation et leur application en therapeutique
BE827337A (fr) Nouveaux derives indazoliques fluores et leur procede de preparation
FR2317298A1 (fr) Nouvelles lactones et leur procede de preparation
FR2285879A1 (fr) Nouveaux derives de guanidine et leur procede de preparation
BE842943A (fr) Nouveaux derives du benzo-cyclohepta-thiophene, leur preparation et leur application en therapeutique
BE856638A (fr) Nouveaux derives de cephalosporine, leur procede, preparation et leur application therapeutique
BE868659A (fr) Nouveaux derives de benzamidine, leur procede de preparation et leurs applications en therapeutique
BE835828A (fr) Nouvelles benzodioxanes-1,4, leur procede de preparation et leur application en therapeutique
BE837605A (fr) Derives de 2-aminoacetamindo- -phenyllenzylidene aminoalcanols, leur procede de preparation et leurs applications en therapeutique

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SMITHKLINE BECKMAN CORP.

Effective date: 19891130