ZA756550B - Pharmaceutical compositions and method of producing antipsychotic activity without extrapyramidal symptoms - Google Patents
Pharmaceutical compositions and method of producing antipsychotic activity without extrapyramidal symptomsInfo
- Publication number
- ZA756550B ZA756550B ZA00756550A ZA756550A ZA756550B ZA 756550 B ZA756550 B ZA 756550B ZA 00756550 A ZA00756550 A ZA 00756550A ZA 756550 A ZA756550 A ZA 756550A ZA 756550 B ZA756550 B ZA 756550B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutical compositions
- antipsychotic activity
- extrapyramidal symptoms
- producing
- producing antipsychotic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/21—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
- C07C65/24—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups polycyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/655,587 US4086350A (en) | 1974-11-06 | 1976-02-05 | Pharmaceutical compositions and method of producing anti-psychotic activity without extrapyramidal symptoms |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52121674A | 1974-11-06 | 1974-11-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA756550B true ZA756550B (en) | 1976-09-29 |
Family
ID=24075868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00756550A ZA756550B (en) | 1974-11-06 | 1975-10-16 | Pharmaceutical compositions and method of producing antipsychotic activity without extrapyramidal symptoms |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5826754B2 (xx) |
| AU (1) | AU498298B2 (xx) |
| BE (1) | BE835224A (xx) |
| CA (1) | CA1055945A (xx) |
| CH (1) | CH624403A5 (xx) |
| DE (1) | DE2549841A1 (xx) |
| DK (1) | DK139429B (xx) |
| ES (1) | ES442357A1 (xx) |
| FR (1) | FR2290202A1 (xx) |
| HU (1) | HU174639B (xx) |
| IE (1) | IE42137B1 (xx) |
| IL (1) | IL48400A (xx) |
| LU (1) | LU73714A1 (xx) |
| NL (1) | NL7512974A (xx) |
| NZ (1) | NZ179139A (xx) |
| PH (1) | PH12158A (xx) |
| ZA (1) | ZA756550B (xx) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2357251A1 (fr) * | 1976-07-09 | 1978-02-03 | Merck & Co Inc | 1-methyl-4-(2-carboxy-1-thioxanthan-9-ylidene)-piperidine |
| US4073912A (en) * | 1976-10-12 | 1978-02-14 | Smithkline Corporation | Piperidylidene derivatives of benzo-fused xanthenes, thioxanthenes and dibenzoxepins and antipsychotic use thereof |
| US4089961A (en) * | 1976-11-08 | 1978-05-16 | Smithkline Corporation | Antipsychotically useful quinolizidylidene derivatives of xanthenes, thioxanthenes and dibenzoxepins |
| NZ189108A (en) * | 1977-12-29 | 1982-02-23 | Kefalas As | 2-methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene and pharmaceutical compositions intermediate 2-methylthio-6-fluoro-9-(1-methyl-4-piperidyl)-thioxanthen-9-ol |
| US4777177A (en) * | 1984-10-19 | 1988-10-11 | Ciba-Geigy Corporation | Pesticidal thioxanthen-9-ylidenepiperidines |
| US5250681A (en) * | 1988-06-02 | 1993-10-05 | Ajinomoto Co., Inc. | Piperidine derivatives and hypotensives containing the same |
| CA2004211A1 (en) * | 1988-11-30 | 1990-05-31 | Masataka Syoji | Piperidine derivatives and hyportensives containing the same |
| US7060711B2 (en) | 2001-10-25 | 2006-06-13 | Biofrontera Bioscience Gmbh | Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist |
| EP1306376A1 (en) * | 2001-10-25 | 2003-05-02 | Biofrontera Pharmaceuticals AG | Derivatives of 4-(thio- or selenoxanthene-9-ylidene)-piperidine or acridine and its use as a selective 5-HT2B receptor antagonist |
| WO2005003131A1 (en) | 2003-06-27 | 2005-01-13 | Janssen Pharmaceutica N.V. | Tricyclic delta opioid modulators |
| AU2005335481A1 (en) | 2004-08-05 | 2007-04-19 | Janssen Pharmaceutica N.V. | Tricyclic delta- opioid modulators |
| EP1833825A1 (en) | 2004-12-22 | 2007-09-19 | Janssen Pharmaceutica N.V. | Tricyclic delta-opioid modulators |
| AU2005319059A1 (en) * | 2004-12-22 | 2006-06-29 | Janssen Pharmaceutica N.V. | Tricyclic delta-opioid modulators |
| ATE432279T1 (de) | 2004-12-22 | 2009-06-15 | Janssen Pharmaceutica Nv | Tricyclische delta-opioid-modulatoren |
| MX2007008286A (es) | 2005-01-06 | 2007-11-12 | Johnson & Johnson | Moduladores delta-opioides triciclicos. |
| TW200716134A (en) | 2005-06-16 | 2007-05-01 | Janssen Pharmaceutica Nv | Tricyclic opioid modulators |
| CA2664345A1 (en) | 2006-09-29 | 2008-04-03 | Nippon Zoki Pharmaceutical Co., Ltd. | Oxepin derivative |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL260070A (xx) * | 1960-02-25 | |||
| NL283292A (xx) * | 1961-09-29 | |||
| DE1670118A1 (de) * | 1966-07-22 | 1970-11-05 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung neuer Derivate des 6,11-Dihydro-dibenz[b,e]oxepins und ihrer Salze |
| US3470188A (en) * | 1967-01-05 | 1969-09-30 | Smithkline Corp | 9-cycloalkyl-lower alkyl-piperidylidene derivatives of xanthenes and thioxanthenes |
| JPS5018478A (xx) * | 1973-05-17 | 1975-02-26 |
-
1975
- 1975-10-16 ZA ZA00756550A patent/ZA756550B/xx unknown
- 1975-10-31 CA CA238,781A patent/CA1055945A/en not_active Expired
- 1975-10-31 AU AU86247/75A patent/AU498298B2/en not_active Expired
- 1975-11-02 IL IL48400A patent/IL48400A/xx unknown
- 1975-11-03 NZ NZ179139A patent/NZ179139A/xx unknown
- 1975-11-03 PH PH17733A patent/PH12158A/en unknown
- 1975-11-03 HU HU75SI1494A patent/HU174639B/hu not_active IP Right Cessation
- 1975-11-04 DK DK495775AA patent/DK139429B/da not_active IP Right Cessation
- 1975-11-04 IE IE2398/75A patent/IE42137B1/en unknown
- 1975-11-04 FR FR7533631A patent/FR2290202A1/fr active Granted
- 1975-11-04 LU LU73714A patent/LU73714A1/xx unknown
- 1975-11-04 BE BE161500A patent/BE835224A/xx not_active IP Right Cessation
- 1975-11-05 ES ES442357A patent/ES442357A1/es not_active Expired
- 1975-11-05 JP JP50133564A patent/JPS5826754B2/ja not_active Expired
- 1975-11-05 NL NL7512974A patent/NL7512974A/xx not_active Application Discontinuation
- 1975-11-05 CH CH1432175A patent/CH624403A5/de not_active IP Right Cessation
- 1975-11-06 DE DE19752549841 patent/DE2549841A1/de active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DK139429C (xx) | 1979-08-06 |
| ES442357A1 (es) | 1977-04-01 |
| IL48400A0 (en) | 1976-01-30 |
| NZ179139A (en) | 1978-04-28 |
| NL7512974A (nl) | 1976-05-10 |
| FR2290202A1 (fr) | 1976-06-04 |
| FR2290202B1 (xx) | 1980-05-23 |
| PH12158A (en) | 1978-11-10 |
| IE42137L (en) | 1976-05-06 |
| LU73714A1 (xx) | 1976-06-11 |
| AU8624775A (en) | 1977-05-05 |
| JPS5826754B2 (ja) | 1983-06-04 |
| HU174639B (hu) | 1980-02-28 |
| DE2549841C2 (xx) | 1988-07-07 |
| DK139429B (da) | 1979-02-19 |
| BE835224A (fr) | 1976-05-04 |
| AU498298B2 (en) | 1979-03-01 |
| IL48400A (en) | 1979-01-31 |
| IE42137B1 (en) | 1980-06-04 |
| CH624403A5 (en) | 1981-07-31 |
| CA1055945A (en) | 1979-06-05 |
| DK495775A (xx) | 1976-05-07 |
| JPS5170768A (xx) | 1976-06-18 |
| DE2549841A1 (de) | 1976-05-13 |
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