YU33015B - Postupak za dobijanje novih derivata n-(trimetoksi-3,4,5 cinamoil)piperazina - Google Patents

Postupak za dobijanje novih derivata n-(trimetoksi-3,4,5 cinamoil)piperazina

Info

Publication number
YU33015B
YU33015B YU834/69A YU83469A YU33015B YU 33015 B YU33015 B YU 33015B YU 834/69 A YU834/69 A YU 834/69A YU 83469 A YU83469 A YU 83469A YU 33015 B YU33015 B YU 33015B
Authority
YU
Yugoslavia
Prior art keywords
trimetoksi
derivata
cinamoil
novih
piperazina
Prior art date
Application number
YU834/69A
Other languages
English (en)
Other versions
YU83469A (en
Inventor
B Pourrias
M Turin
Original Assignee
Delalande Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande Sa filed Critical Delalande Sa
Publication of YU83469A publication Critical patent/YU83469A/xx
Publication of YU33015B publication Critical patent/YU33015B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
YU834/69A 1968-04-03 1969-04-03 Postupak za dobijanje novih derivata n-(trimetoksi-3,4,5 cinamoil)piperazina YU33015B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB06113/68A GB1218591A (en) 1968-04-03 1968-04-03 Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation

Publications (2)

Publication Number Publication Date
YU83469A YU83469A (en) 1975-06-30
YU33015B true YU33015B (en) 1976-03-31

Family

ID=10071423

Family Applications (1)

Application Number Title Priority Date Filing Date
YU834/69A YU33015B (en) 1968-04-03 1969-04-03 Postupak za dobijanje novih derivata n-(trimetoksi-3,4,5 cinamoil)piperazina

Country Status (17)

Country Link
US (1) US3634411A (xx)
BE (1) BE730345A (xx)
BG (1) BG15397A3 (xx)
CH (1) CH498845A (xx)
CS (1) CS163733B2 (xx)
DK (1) DK123824C (xx)
FI (1) FI51190C (xx)
FR (1) FR2007372A1 (xx)
GB (1) GB1218591A (xx)
IL (1) IL31901A (xx)
IT (1) IT1036019B (xx)
LU (1) LU58316A1 (xx)
NL (1) NL147427B (xx)
NO (1) NO124312B (xx)
RO (1) RO55704A (xx)
SE (1) SE351212B (xx)
YU (1) YU33015B (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2092703A1 (en) * 1970-06-10 1972-01-28 Delalande Sa 2-(1-pyrrolidinocarbonylmethyl-piperazin-4-yl) ethyl - 3,4,5-trimethoxy benzoate - having hypotensive and adrenolytic active
FR2092902A1 (en) * 1970-06-30 1972-01-28 Delalande Sa Substd propiophenone - beta (pyrrolidino carbonylmethyl)-1'-piperazin propiophenones, analgesics, hypotensives adrenolytics, noradrenolytic
FR2278340A1 (fr) * 1974-07-17 1976-02-13 Delalande Sa Nouveau derive de la n-(trimethoxy-3,4,5 cinnamoyl) piperazine, ses sels d'addition d'acides, son procede de preparation et son application en therapeutique
GB1473262A (en) * 1974-11-20 1977-05-11 Delalande Sa Derivatives of n-3,4,5-trimethoxy cinnamoyl-piperazine their process of preparation and their therapeutic application
GR71991B (xx) * 1980-01-21 1983-08-26 Delalande Sa
JPS5888370A (ja) * 1981-11-19 1983-05-26 Hokuriku Seiyaku Co Ltd １−（３，４，５−トリメトキシシンナモイル）−４−アミノカルボニルエチル置換ピペラジン及びホモピペラジン誘導体、及びその製造方法
IT1151104B (it) * 1982-02-04 1986-12-17 Delalande Sa Impiego terapeutico di derivati (1-cinnamoil oppure 1-fenetil-carbonil)piperazinici
FR2522325B1 (fr) * 1982-02-26 1985-08-09 Delalande Sa Nouveaux derives aryliques de la piperazine, de l'homopiperazine et de n,n'-dialkyl diamino-1,2 ethane, leur procede de preparation et leur application en therapeutique
FR2552762B1 (fr) * 1983-09-30 1986-07-25 Delalande Sa Nouveaux amides piperaziniques et homopiperaziniques derives de l'acide 3,4-dioxymethylene cinnamique, leur procede de preparation et leur application en therapeutique
JPS6172773A (ja) * 1984-09-17 1986-04-14 Terumo Corp ピペラジン誘導体およびこれを含有する血管拡張剤
US6011035A (en) * 1998-06-30 2000-01-04 Neuromed Technologies Inc. Calcium channel blockers
ATE502635T1 (de) 2002-08-19 2011-04-15 Pfizer Kombinationstherapie gegen hyperproliferative erkrankungen
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
US8383660B2 (en) 2006-03-10 2013-02-26 Pfizer Inc. Dibenzyl amine compounds and derivatives
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
WO2009010429A2 (en) * 2007-07-19 2009-01-22 F. Hoffmann-La Roche Ag Novel heterocyclyl compounds and their use as chemokine antagonists
CN101260092B (zh) * 2008-04-14 2011-07-20 罗军 马来酸桂哌齐特的制备方法
CN101723918B (zh) * 2008-10-24 2011-08-31 重庆医科大学医药研究所 马来酸桂哌齐特的制备工艺
CN101531643B (zh) * 2009-04-13 2012-11-14 上海理奥生物医药科技有限责任公司 一种改进的马来酸桂哌齐特的合成方法
CN102229583B (zh) * 2011-05-13 2013-11-27 江苏神龙药业有限公司 一种桂哌齐特的合成方法
CN103664830A (zh) * 2012-09-05 2014-03-26 凌沛学 一种马来酸桂哌齐特改进的合成方法
CN103896878B (zh) * 2012-12-26 2018-02-09 江苏万邦生化医药股份有限公司 一种桂哌齐特的纯化脱色方法
CN103245734A (zh) * 2013-01-18 2013-08-14 沈阳亿灵医药科技有限公司 一组控制马来酸桂哌齐特质量的组合物
KR101695582B1 (ko) 2013-04-17 2017-01-13 화이자 인코포레이티드 심혈관 질환을 치료하기 위한 n-피페리딘-3-일벤즈아미드 유도체
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
MX2021008533A (es) 2019-01-18 2021-08-19 Astrazeneca Ab Inhibidores de la pcsk9 y metodos de uso de los mismos.

Also Published As

Publication number Publication date
FI51190C (fi) 1976-11-10
RO55704A (xx) 1974-01-03
GB1218591A (en) 1971-01-06
NL147427B (nl) 1975-10-15
IL31901A (en) 1972-03-28
SE351212B (xx) 1972-11-20
CH498845A (fr) 1970-11-15
DE1915795B2 (de) 1975-07-03
FR2007372A1 (xx) 1970-01-09
FI51190B (xx) 1976-08-02
US3634411A (en) 1972-01-11
NO124312B (xx) 1972-04-04
BE730345A (xx) 1969-09-21
LU58316A1 (xx) 1969-10-27
IT1036019B (it) 1979-10-30
BG15397A3 (bg) 1976-05-26
CS163733B2 (xx) 1975-11-07
DK123824C (da) 1972-12-18
YU83469A (en) 1975-06-30
IL31901A0 (en) 1969-05-28
DE1915795A1 (de) 1970-09-10
NL6905019A (xx) 1969-10-07
DK123824B (xx) 1972-08-07

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