LTPA2021002I1 - Kvinolono junginių gamybos būdas - Google Patents

Kvinolono junginių gamybos būdas

Info

Publication number
LTPA2021002I1
LTPA2021002I1 LTPA2021002C LTPA2021002C LTPA2021002I1 LT PA2021002 I1 LTPA2021002 I1 LT PA2021002I1 LT PA2021002 C LTPA2021002 C LT PA2021002C LT PA2021002 C LTPA2021002 C LT PA2021002C LT PA2021002 I1 LTPA2021002 I1 LT PA2021002I1
Authority
LT
Lithuania
Prior art keywords
production
quinolone compounds
quinolone
compounds
Prior art date
Application number
LTPA2021002C
Other languages
English (en)
Original Assignee
Melinta Subsidiary Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Melinta Subsidiary Corp. filed Critical Melinta Subsidiary Corp.
Publication of LTPA2021002I1 publication Critical patent/LTPA2021002I1/lt
Publication of LTC3214083I2 publication Critical patent/LTC3214083I2/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicinal Preparation (AREA)
LTPA2021002C 2008-09-24 2021-02-17 Kvinolono junginių gamybos būdas LTC3214083I2 (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19408308P 2008-09-24 2008-09-24
PCT/US2009/005276 WO2010036329A2 (en) 2008-09-24 2009-09-23 Process for making quinolone compounds
EP09816565.7A EP2346855B1 (en) 2008-09-24 2009-09-23 Process for making quinolone compounds

Publications (2)

Publication Number Publication Date
LTPA2021002I1 true LTPA2021002I1 (lt) 2021-03-10
LTC3214083I2 LTC3214083I2 (lt) 2022-06-27

Family

ID=42060333

Family Applications (3)

Application Number Title Priority Date Filing Date
LTEP20191961.0T LT3766876T (lt) 2008-09-24 2009-09-23 Farmacinė vaisto forma, turinti chinolono darinį
LTEP17163383.7T LT3214083T (lt) 2008-09-24 2009-09-23 Kvinolono junginių gamybos būdas
LTPA2021002C LTC3214083I2 (lt) 2008-09-24 2021-02-17 Kvinolono junginių gamybos būdas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
LTEP20191961.0T LT3766876T (lt) 2008-09-24 2009-09-23 Farmacinė vaisto forma, turinti chinolono darinį
LTEP17163383.7T LT3214083T (lt) 2008-09-24 2009-09-23 Kvinolono junginių gamybos būdas

Country Status (27)

Country Link
US (3) USRE46617E1 (lt)
EP (3) EP3766876B8 (lt)
JP (2) JP6013734B2 (lt)
KR (3) KR20110091504A (lt)
CN (2) CN102164912B (lt)
AU (1) AU2009297085B2 (lt)
BR (1) BRPI0919241B8 (lt)
CA (1) CA2738236C (lt)
CY (1) CY1123658T1 (lt)
DK (2) DK2346855T3 (lt)
ES (3) ES2629466T3 (lt)
FI (1) FI3766876T3 (lt)
HK (2) HK1214243A1 (lt)
HR (1) HRP20201879T1 (lt)
HU (2) HUE052219T2 (lt)
IL (1) IL211845A (lt)
LT (3) LT3766876T (lt)
MX (2) MX2011003122A (lt)
NL (1) NL301091I2 (lt)
NO (1) NO2021006I1 (lt)
PL (2) PL3766876T3 (lt)
PT (1) PT3214083T (lt)
RS (1) RS61194B1 (lt)
RU (1) RU2546667C2 (lt)
SG (1) SG10201605492YA (lt)
SI (1) SI3214083T1 (lt)
WO (1) WO2010036329A2 (lt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7576216B2 (en) * 2004-07-30 2009-08-18 Abbott Laboratories Preparation of pyridonecarboxylic acid antibacterials
KR20110091504A (ko) * 2008-09-24 2011-08-11 립-엑스 파마슈티칼즈, 인크. 퀴놀론 화합물의 제조 방법
TW201444558A (zh) * 2013-03-15 2014-12-01 Melinta Therapeutics Inc 使用喹諾酮類抗生素治療淋病感染的方法
CN104098548B (zh) * 2013-04-11 2017-07-18 上海医药工业研究院 一种Delafloxacin的精制方法
CN103709100A (zh) * 2013-12-31 2014-04-09 南京工业大学 一种8-氯代喹诺酮衍生物的制备方法
TW201605447A (zh) * 2014-06-20 2016-02-16 美林塔治療學有限公司 處理感染的方法
CN106256824B (zh) * 2015-06-18 2020-10-27 重庆医药工业研究院有限责任公司 一种高纯度德拉沙星葡甲胺盐的制备方法
CN105017224A (zh) * 2015-07-10 2015-11-04 扬子江药业集团有限公司 一种德拉沙星葡甲胺晶型的制备方法
CN107778293B (zh) * 2016-08-29 2023-06-16 鲁南制药集团股份有限公司 一种改进的德拉沙星的制备方法
BR112019020401A2 (pt) 2017-03-31 2020-04-22 Fujifilm Corp composto 4-piridona ou seu sal, e composição farmacêutica e formulação que inclui o mesmo
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
CN113527262B (zh) * 2021-06-22 2022-07-15 安徽普利药业有限公司 一种德拉沙星及其葡甲胺盐的精制方法
CN114031607B (zh) * 2021-11-16 2023-01-10 海南普利制药股份有限公司 一种德拉沙星及其中间体的精制方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
JP3103380B2 (ja) 1995-09-22 2000-10-30 湧永製薬株式会社 新規ピリドンカルボン酸誘導体又はその塩並びに該物質を有効成分とする抗菌剤
PT1193266E (pt) * 1999-07-01 2003-12-31 Wakunaga Pharma Co Ltd Derivado do acido quinolinacarboxilico e os sais dele derivados
JP2005097116A (ja) 1999-11-11 2005-04-14 Wakunaga Pharmaceut Co Ltd キノリンカルボン酸誘導体アルカリ金属塩及びこれを用いたキノリンカルボン酸誘導体の精製法
WO2006015194A2 (en) * 2004-07-30 2006-02-09 Abbott Laboratories Preparation of pyridonecarboxylic acid antibacterials
DK3056492T3 (da) 2004-10-08 2021-12-13 Abbvie Inc Megluminsalt og krystallinke former deraf af et lægemiddel (delafloxacin)
PL1868581T3 (pl) * 2005-04-11 2012-08-31 Abbvie Inc Kompozycje farmaceutyczne słabo rozpuszczalnych leków o polepszonych profilach rozpuszczania
KR20110091504A (ko) 2008-09-24 2011-08-11 립-엑스 파마슈티칼즈, 인크. 퀴놀론 화합물의 제조 방법

Also Published As

Publication number Publication date
NO2021006I1 (no) 2021-02-15
LT3766876T (lt) 2023-12-11
AU2009297085A1 (en) 2010-04-01
KR20170039758A (ko) 2017-04-11
IL211845A (en) 2017-03-30
EP2346855B1 (en) 2017-04-05
KR20160116020A (ko) 2016-10-06
EP3766876A1 (en) 2021-01-20
FI3766876T3 (fi) 2023-12-05
BRPI0919241A8 (pt) 2017-10-17
IL211845A0 (en) 2011-06-30
EP3214083A1 (en) 2017-09-06
LT3214083T (lt) 2021-01-25
MX2020009790A (es) 2020-10-12
EP3766876B8 (en) 2023-10-18
HK1244481A1 (zh) 2018-08-10
HUE052219T2 (hu) 2021-04-28
PL3214083T3 (pl) 2021-04-06
US8497378B2 (en) 2013-07-30
DK3214083T3 (da) 2020-12-07
BRPI0919241B1 (pt) 2020-05-12
SG10201605492YA (en) 2016-09-29
WO2010036329A2 (en) 2010-04-01
JP6013734B2 (ja) 2016-10-25
USRE46617E1 (en) 2017-11-28
CN102164912A (zh) 2011-08-24
CN102164912B (zh) 2015-08-19
PT3214083T (pt) 2020-12-04
US8871938B2 (en) 2014-10-28
HK1214243A1 (zh) 2016-07-22
US20140171648A1 (en) 2014-06-19
CY1123658T1 (el) 2021-05-05
BRPI0919241A2 (pt) 2016-06-21
KR101775304B1 (ko) 2017-09-05
ES2826273T3 (es) 2021-05-17
EP3214083B1 (en) 2020-09-16
ES2966093T3 (es) 2024-04-18
ES2629466T3 (es) 2017-08-09
KR20110091504A (ko) 2011-08-11
RU2546667C2 (ru) 2015-04-10
HUS2100004I1 (hu) 2021-03-01
EP2346855A4 (en) 2012-07-04
JP2012508161A (ja) 2012-04-05
NL301091I1 (nl) 2021-02-10
CN105001207A (zh) 2015-10-28
MX2011003122A (es) 2011-07-20
RU2011116052A (ru) 2012-10-27
AU2009297085B2 (en) 2015-07-09
PL3766876T3 (pl) 2024-04-02
WO2010036329A3 (en) 2010-07-01
CA2738236C (en) 2016-11-15
HRP20201879T1 (hr) 2021-01-22
JP2015178515A (ja) 2015-10-08
EP3766876B1 (en) 2023-09-13
BRPI0919241B8 (pt) 2021-05-25
LTC3214083I2 (lt) 2022-06-27
RS61194B1 (sr) 2021-01-29
DK2346855T3 (en) 2017-07-24
US20120041208A1 (en) 2012-02-16
NL301091I2 (nl) 2021-08-03
SI3214083T1 (sl) 2021-02-26
CA2738236A1 (en) 2010-04-01
EP2346855A2 (en) 2011-07-27

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