CN104098548B - 一种Delafloxacin的精制方法 - Google Patents
一种Delafloxacin的精制方法 Download PDFInfo
- Publication number
- CN104098548B CN104098548B CN201310124425.9A CN201310124425A CN104098548B CN 104098548 B CN104098548 B CN 104098548B CN 201310124425 A CN201310124425 A CN 201310124425A CN 104098548 B CN104098548 B CN 104098548B
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- delafloxacin
- ethanol
- stirring
- purification
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
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Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201310124425.9A CN104098548B (zh) | 2013-04-11 | 2013-04-11 | 一种Delafloxacin的精制方法 |
Applications Claiming Priority (1)
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CN201310124425.9A CN104098548B (zh) | 2013-04-11 | 2013-04-11 | 一种Delafloxacin的精制方法 |
Publications (2)
Publication Number | Publication Date |
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CN104098548A CN104098548A (zh) | 2014-10-15 |
CN104098548B true CN104098548B (zh) | 2017-07-18 |
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CN201310124425.9A Active CN104098548B (zh) | 2013-04-11 | 2013-04-11 | 一种Delafloxacin的精制方法 |
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CN (1) | CN104098548B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105693695A (zh) * | 2014-11-24 | 2016-06-22 | 重庆医药工业研究院有限责任公司 | 一种德拉沙星葡甲胺盐的晶型及其制备方法 |
CN106256824B (zh) * | 2015-06-18 | 2020-10-27 | 重庆医药工业研究院有限责任公司 | 一种高纯度德拉沙星葡甲胺盐的制备方法 |
CN105968099B (zh) * | 2016-05-12 | 2018-09-25 | 扬子江药业集团有限公司 | 一种德拉沙星的精制方法 |
CN108084161A (zh) * | 2017-12-28 | 2018-05-29 | 北京沃邦医药科技有限公司 | 德拉沙星及其中间体的制备方法 |
CN113527262B (zh) * | 2021-06-22 | 2022-07-15 | 安徽普利药业有限公司 | 一种德拉沙星及其葡甲胺盐的精制方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102146087A (zh) * | 2010-02-10 | 2011-08-10 | 广东东阳光药业有限公司 | 一种制备高纯度左氧氟沙星半水合物的方法 |
CN102164912A (zh) * | 2008-09-24 | 2011-08-24 | Rib-X制药有限公司 | 制备喹诺酮类化合物的工艺 |
Family Cites Families (2)
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JP3103380B2 (ja) * | 1995-09-22 | 2000-10-30 | 湧永製薬株式会社 | 新規ピリドンカルボン酸誘導体又はその塩並びに該物質を有効成分とする抗菌剤 |
PL1868581T3 (pl) * | 2005-04-11 | 2012-08-31 | Abbvie Inc | Kompozycje farmaceutyczne słabo rozpuszczalnych leków o polepszonych profilach rozpuszczania |
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2013
- 2013-04-11 CN CN201310124425.9A patent/CN104098548B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102164912A (zh) * | 2008-09-24 | 2011-08-24 | Rib-X制药有限公司 | 制备喹诺酮类化合物的工艺 |
CN102146087A (zh) * | 2010-02-10 | 2011-08-10 | 广东东阳光药业有限公司 | 一种制备高纯度左氧氟沙星半水合物的方法 |
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Publication number | Publication date |
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CN104098548A (zh) | 2014-10-15 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C41 | Transfer of patent application or patent right or utility model | ||
CB03 | Change of inventor or designer information |
Inventor after: Kong Rui Inventor after: Yuan Zhedong Inventor after: Liu Xiangkui Inventor after: Chen Pan Inventor after: Gu Hongmei Inventor after: Wang Xiangjian Inventor before: Kong Rui Inventor before: Yuan Zhedong Inventor before: Liu Xiangkui Inventor before: Chen Pan |
|
COR | Change of bibliographic data | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20160412 Address after: 200040 Beijing West Road, Shanghai, No. 1320, No. Applicant after: Shanghai Institute of pharmaceutical industry Applicant after: China State Institute of Pharmaceutical Industry Applicant after: Chia Tai Tianqing Pharmaceutical Group Co., Ltd. Address before: 200040 Beijing West Road, Shanghai, No. 1320, No. Applicant before: Shanghai Institute of pharmaceutical industry Applicant before: China State Institute of Pharmaceutical Industry |
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GR01 | Patent grant | ||
GR01 | Patent grant |