LT4649B - Stanolio kompozicija ir jos panaudojimas - Google Patents
Stanolio kompozicija ir jos panaudojimas Download PDFInfo
- Publication number
- LT4649B LT4649B LT99-018A LT99018A LT4649B LT 4649 B LT4649 B LT 4649B LT 99018 A LT99018 A LT 99018A LT 4649 B LT4649 B LT 4649B
- Authority
- LT
- Lithuania
- Prior art keywords
- sitostanol
- cholesterol
- stanol
- campestanol
- fatty acid
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 96
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- 238000003556 assay Methods 0.000 description 1
- 235000013734 beta-carotene Nutrition 0.000 description 1
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 1
- 239000011648 beta-carotene Substances 0.000 description 1
- 229960002747 betacarotene Drugs 0.000 description 1
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- 238000004587 chromatography analysis Methods 0.000 description 1
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- 150000001875 compounds Chemical class 0.000 description 1
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- 238000010411 cooking Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000004332 deodorization Methods 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
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- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000003995 emulsifying agent Substances 0.000 description 1
- 239000010696 ester oil Substances 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- ZYNDJIBBPLNPOW-UHFFFAOYSA-N eurucic acid methyl ester Natural products CCCCCCCCC=CCCCCCCCCCCCC(=O)OC ZYNDJIBBPLNPOW-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 238000001030 gas--liquid chromatography Methods 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000009884 interesterification Methods 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000010746 mayonnaise Nutrition 0.000 description 1
- 239000008268 mayonnaise Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 150000004702 methyl esters Chemical class 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 210000002741 palatine tonsil Anatomy 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- LGJMUZUPVCAVPU-GJAZBXDESA-N poriferastan-3beta-ol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@H](CC)C(C)C)[C@@]2(C)CC1 LGJMUZUPVCAVPU-GJAZBXDESA-N 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 235000012045 salad Nutrition 0.000 description 1
- 235000014438 salad dressings Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- QDRKDTQENPPHOJ-UHFFFAOYSA-N sodium ethoxide Chemical compound [Na+].CC[O-] QDRKDTQENPPHOJ-UHFFFAOYSA-N 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 238000005292 vacuum distillation Methods 0.000 description 1
- 241000228158 x Triticosecale Species 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Edible Oils And Fats (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Seasonings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FI963126A FI107015B (fi) | 1996-08-09 | 1996-08-09 | Kasvistanolirasvahappoestereiden seos ja sen käyttö sekä elintarvike |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LT99018A LT99018A (en) | 1999-12-27 |
| LT4649B true LT4649B (lt) | 2000-04-25 |
Family
ID=8546469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LT99-018A LT4649B (lt) | 1996-08-09 | 1999-02-26 | Stanolio kompozicija ir jos panaudojimas |
Country Status (27)
| Country | Link |
|---|---|
| EP (2) | EP1452180A1 (pt) |
| JP (3) | JP2000513730A (pt) |
| KR (1) | KR100440640B1 (pt) |
| CN (1) | CN1165312C (pt) |
| AT (1) | ATE266408T1 (pt) |
| AU (1) | AU734418B2 (pt) |
| BR (1) | BRPI9612693B8 (pt) |
| CA (1) | CA2262600C (pt) |
| CZ (1) | CZ290903B6 (pt) |
| DE (1) | DE69632481T3 (pt) |
| DK (1) | DK0871451T4 (pt) |
| EE (1) | EE03747B1 (pt) |
| ES (1) | ES2220986T5 (pt) |
| FI (1) | FI107015B (pt) |
| HU (1) | HU228301B1 (pt) |
| IL (1) | IL128458A (pt) |
| LT (1) | LT4649B (pt) |
| LV (1) | LV12307B (pt) |
| NO (1) | NO326262B1 (pt) |
| NZ (1) | NZ334496A (pt) |
| PL (1) | PL331515A1 (pt) |
| PT (1) | PT871451E (pt) |
| SI (1) | SI9620141B (pt) |
| SK (1) | SK285849B6 (pt) |
| UA (1) | UA66763C2 (pt) |
| WO (1) | WO1998006405A1 (pt) |
| ZA (1) | ZA967616B (pt) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6544973B1 (en) | 1995-07-28 | 2003-04-08 | Raisio Benecol Ltd. | Substance for lowering high cholesterol level in serum and methods for preparing and using the same |
| US5502045A (en) | 1991-05-03 | 1996-03-26 | Raision Tehtaat Oy Ab | Use of a stanol fatty acid ester for reducing serum cholesterol level |
| US6262277B1 (en) | 1994-09-13 | 2001-07-17 | G.D. Searle And Company | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
| US20030104035A1 (en) | 1996-08-09 | 2003-06-05 | Raisio Benecol Ltd. | Stanol composition and the use thereof |
| UA69378C2 (uk) | 1996-11-04 | 2004-09-15 | Райзіо Бенекол Лтд. | Текстуруюча композиція, текстуруючий агент, харчовий продукт, жирові суміші та способи їх одержання |
| US6929816B2 (en) | 1998-01-21 | 2005-08-16 | Raisio Benecol Ltd. | Fat compositions for use in food |
| FI107538B (fi) | 1997-02-26 | 2001-08-31 | Raisio Benecol Oy | Menetelmä stanoliesterien valmistamiseksi |
| EP0897971B1 (en) * | 1997-08-22 | 2004-11-03 | Unilever N.V. | Stanol ester composition |
| EP1440619B1 (en) * | 1997-08-22 | 2006-11-02 | Unilever N.V. | Fat based food products comprising sterols |
| DK0897970T3 (da) * | 1997-08-22 | 2004-11-08 | Unilever Nv | Fremgangsmåde til fremstilling af stanolestere |
| DK0898896T3 (da) * | 1997-08-22 | 2004-10-18 | Unilever Nv | Næringsmidler på grundlag af fedtstoffer indeholdende steroler |
| ES2272882T3 (es) * | 1997-08-22 | 2007-05-01 | Unilever N.V. | Composciones que comprenden estanol. |
| DE69827330T2 (de) * | 1997-08-22 | 2006-02-02 | Unilever N.V. | Stanolester enthaltende Zusammensetzung |
| FI974648A (fi) * | 1997-09-09 | 1999-05-06 | Raisio Benecol Oy | Hydroksihappo-, maitohappo- ja hydroksialkanoaattiesterit ja niiden käyttö |
| EP1066313A1 (de) * | 1998-03-23 | 2001-01-10 | Cognis Deutschland GmbH | Verfahren zur herstellung von stanolen |
| US6025348A (en) * | 1998-04-30 | 2000-02-15 | Kao Corporation | Oil and fat composition containing phytosterol |
| US6123978A (en) * | 1998-08-31 | 2000-09-26 | Mcneil-Ppc, Inc. | Stable salad dressings |
| US6277431B1 (en) * | 1998-10-14 | 2001-08-21 | Redeem, Inc. | Anticholesterolemic edible oil |
| FI115527B (fi) * | 1998-10-16 | 2005-05-31 | Upm Kymmene Oyj | Kasvisterolijohdannaisten käyttö ja niitä sisältäviä tuotteita |
| NZ501169A (en) * | 1998-11-26 | 2001-05-25 | F | Fatty acid esters of phytosterol and phytostanol |
| US6113972A (en) * | 1998-12-03 | 2000-09-05 | Monsanto Co. | Phytosterol protein complex |
| AU3228100A (en) | 1999-02-10 | 2000-08-29 | Eastman Chemical Company | Corn fiber for the production of advanced chemicals and materials |
| MXPA01010304A (es) * | 1999-04-12 | 2002-05-06 | Monsanto Technology Llc | Plantas transgenicas que contienen niveles alterados de compuestos de esterol y tocoferoles. |
| FI991533A (fi) * | 1999-07-05 | 2001-01-06 | Sohkar Oy | Menetelmä orgaanisten aineiden käsittelemiseksi |
| US7157619B1 (en) | 1999-08-30 | 2007-01-02 | Monsanto Technology, L.L.C. | Plant sterol acyltransferases |
| US6998501B1 (en) | 1999-08-30 | 2006-02-14 | Ocean Nutrition Canada Limited | Nutritional supplement for lowering serum triglyceride and cholesterol levels |
| WO2001015552A1 (en) * | 1999-08-30 | 2001-03-08 | Ocean Nutrition Canada Ltd. | A nutritional supplement for lowering serum triglyceride and cholesterol levels |
| US6677327B1 (en) | 1999-11-24 | 2004-01-13 | Archer-Daniels-Midland Company | Phytosterol and phytostanol compositions |
| BR0107707A (pt) * | 2000-01-21 | 2004-01-06 | Forbes Medi Tech Inc | Compósitos cristalinos compreendendo fitoesteróis e fitoestanóis ou derivados dos mesmos |
| CA2395447A1 (en) | 2000-01-28 | 2001-08-02 | Robert Joseph Sarama | Palatable arginine compounds and uses thereof for cardiovascular health |
| ES2298197T3 (es) * | 2000-01-31 | 2008-05-16 | Harting S.A. | Composiciones que contienen esteres de acidos grasos de fitosterol y de policosanol para reducir el colesterol y los trigliceridos de la sangre. |
| CN1436047A (zh) | 2000-04-14 | 2003-08-13 | 马尔斯公司 | 促进血管健康的组合物和方法 |
| FI20010780A0 (fi) * | 2001-04-12 | 2001-04-12 | Raisio Benecol Oy | Parannetut koostumukset |
| GB0329667D0 (en) | 2003-12-22 | 2004-01-28 | King S College London | Core 2 GlcNAc-T inhibitor |
| GB0513881D0 (en) | 2005-07-06 | 2005-08-10 | Btg Int Ltd | Core 2 GLCNAC-T Inhibitors III |
| US20080182801A1 (en) | 2003-12-22 | 2008-07-31 | Btg International Limited | Core 2 glcnac-t inhibitors |
| US8158184B2 (en) | 2004-03-08 | 2012-04-17 | Bunge Oils, Inc. | Structured lipid containing compositions and methods with health and nutrition promoting characteristics |
| GB0513888D0 (en) | 2005-07-06 | 2005-08-10 | Btg Int Ltd | Core 2 GLCNAC-T Inhibitors II |
| GB0513883D0 (en) | 2005-07-06 | 2005-08-10 | Btg Int Ltd | Diagnosis of Atherosclerosis |
| WO2007036920A2 (en) * | 2005-09-28 | 2007-04-05 | Alltracel Development Services Limited | Therapeutic use of polyanhydroglucronic acid |
| KR20080108969A (ko) * | 2005-12-20 | 2008-12-16 | 포비스 메디-테크 인코포레이티드 | 수성 상에 비에스테르화 파이토스테롤을 포함하는 에멀젼 |
| US20070148311A1 (en) | 2005-12-22 | 2007-06-28 | Bunge Oils, Inc. | Phytosterol esterification product and method of make same |
| WO2007101581A2 (de) * | 2006-03-08 | 2007-09-13 | Cognis Ip Management Gmbh | Sterolhaltige pulver |
| DE102006041302A1 (de) * | 2006-03-08 | 2007-09-13 | Cognis Ip Management Gmbh | Sterolester mit kurzkettigen Fettsäuren |
| US20080124387A1 (en) | 2006-11-27 | 2008-05-29 | Kapac, Llc | Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients |
| FI123374B (fi) | 2011-03-25 | 2013-03-15 | Ravintoraisio Oy | Uusi syötävä koostumus |
| EP3287014B1 (de) * | 2016-08-22 | 2020-02-26 | Verbio Vereinigte Bioenergie AG | Verfahren zur herstellung einer phytosterol-phytostanolzusammensetzung |
| WO2021170873A1 (en) * | 2020-02-27 | 2021-09-02 | Basf Se | Composition for the treatment of (pre)hypercholesterolemia and/or associated morbidities thereto |
| GB202110358D0 (en) * | 2021-07-19 | 2021-09-01 | Meda Pharma S P A | Composition |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5502045A (en) * | 1991-05-03 | 1996-03-26 | Raision Tehtaat Oy Ab | Use of a stanol fatty acid ester for reducing serum cholesterol level |
| US5244887A (en) * | 1992-02-14 | 1993-09-14 | Straub Carl D | Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof |
-
1996
- 1996-08-09 FI FI963126A patent/FI107015B/fi not_active IP Right Cessation
- 1996-09-02 EP EP04011018A patent/EP1452180A1/en not_active Withdrawn
- 1996-09-02 PT PT96928481T patent/PT871451E/pt unknown
- 1996-09-02 NZ NZ334496A patent/NZ334496A/xx not_active IP Right Cessation
- 1996-09-02 BR BRPI9612693A patent/BRPI9612693B8/pt not_active IP Right Cessation
- 1996-09-02 SI SI9620141A patent/SI9620141B/sl active Search and Examination
- 1996-09-02 DE DE69632481T patent/DE69632481T3/de not_active Expired - Lifetime
- 1996-09-02 ES ES96928481T patent/ES2220986T5/es not_active Expired - Lifetime
- 1996-09-02 CA CA002262600A patent/CA2262600C/en not_active Expired - Lifetime
- 1996-09-02 CZ CZ1999346A patent/CZ290903B6/cs not_active IP Right Cessation
- 1996-09-02 PL PL96331515A patent/PL331515A1/xx unknown
- 1996-09-02 AU AU68230/96A patent/AU734418B2/en not_active Expired
- 1996-09-02 HU HU0001020A patent/HU228301B1/hu not_active IP Right Cessation
- 1996-09-02 EP EP96928481A patent/EP0871451B2/en not_active Expired - Lifetime
- 1996-09-02 DK DK96928481T patent/DK0871451T4/da active
- 1996-09-02 WO PCT/FI1996/000465 patent/WO1998006405A1/en active IP Right Grant
- 1996-09-02 AT AT96928481T patent/ATE266408T1/de active
- 1996-09-02 EE EEP199900040A patent/EE03747B1/xx not_active IP Right Cessation
- 1996-09-02 UA UA99021088A patent/UA66763C2/xx unknown
- 1996-09-02 CN CNB961804068A patent/CN1165312C/zh not_active Expired - Lifetime
- 1996-09-02 SK SK112-99A patent/SK285849B6/sk not_active IP Right Cessation
- 1996-09-02 KR KR10-1999-7001057A patent/KR100440640B1/ko not_active IP Right Cessation
- 1996-09-02 JP JP10509427A patent/JP2000513730A/ja not_active Withdrawn
- 1996-09-02 IL IL12845896A patent/IL128458A/en not_active IP Right Cessation
- 1996-09-10 ZA ZA967616A patent/ZA967616B/xx unknown
-
1999
- 1999-02-05 NO NO19990559A patent/NO326262B1/no not_active IP Right Cessation
- 1999-02-26 LT LT99-018A patent/LT4649B/lt not_active IP Right Cessation
- 1999-03-09 LV LVP-99-41A patent/LV12307B/en unknown
-
2003
- 2003-12-03 JP JP2003405151A patent/JP4554915B2/ja not_active Expired - Fee Related
-
2009
- 2009-02-04 JP JP2009024241A patent/JP2009102421A/ja active Pending
Non-Patent Citations (5)
| Title |
|---|
| B. DAYAL ET AL.: "Identification of 5α-stanols in patients with sitosterolemia and xanthomatosis: stereochemistry of the protonolysis of steroidal organoboranes.", STEROIDS, 1982, pages 233 - 243, XP023429562, DOI: doi:10.1016/0039-128X(82)90036-8 |
| GRETEN H.: "Lipoprotein metabolism", pages: 112 - 118 |
| GRETEN H.: "Lipoprotein metabolism", pages: 119 - 124 |
| LING W H: "Minireview dietary phytosterols: A review of metabolism", LIFE SCIENCES, 1995, pages 195 - 206, XP000995149, DOI: doi:10.1016/0024-3205(95)00263-6 |
| POLLAK OJ: "Effect of plant sterols on serum lipids and atherosclerosis", PHARMAC THER, 1985, pages 117 - 208 |
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|---|---|---|---|
| MM9A | Lapsed patents |
Effective date: 20130902 |