LT3417B - Blood coagulation factor xi concentrate and process for the preparing same - Google Patents

Blood coagulation factor xi concentrate and process for the preparing same Download PDF

Info

Publication number
LT3417B
LT3417B LTIP265A LTIP265A LT3417B LT 3417 B LT3417 B LT 3417B LT IP265 A LTIP265 A LT IP265A LT IP265 A LTIP265 A LT IP265A LT 3417 B LT3417 B LT 3417B
Authority
LT
Lithuania
Prior art keywords
factor
filter
concentrate
sodium chloride
buffer
Prior art date
Application number
LTIP265A
Other languages
English (en)
Lithuanian (lt)
Inventor
Miryana Burnouf
Dominique Dernis
Original Assignee
Aetsrn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aetsrn filed Critical Aetsrn
Publication of LTIP265A publication Critical patent/LTIP265A/xx
Publication of LT3417B publication Critical patent/LT3417B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6443—Coagulation factor XIa (3.4.21.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21027—Coagulation factor XIa (3.4.21.27)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
LTIP265A 1991-05-07 1992-12-29 Blood coagulation factor xi concentrate and process for the preparing same LT3417B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105572A FR2676231A1 (fr) 1991-05-07 1991-05-07 Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.

Publications (2)

Publication Number Publication Date
LTIP265A LTIP265A (en) 1994-10-25
LT3417B true LT3417B (en) 1995-09-25

Family

ID=9412593

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP265A LT3417B (en) 1991-05-07 1992-12-29 Blood coagulation factor xi concentrate and process for the preparing same

Country Status (16)

Country Link
US (1) US5252217A (da)
EP (1) EP0512883B1 (da)
AT (1) ATE156360T1 (da)
AU (1) AU652043B2 (da)
BR (1) BR9201718A (da)
CA (1) CA2068069C (da)
DE (1) DE69221369T2 (da)
DK (1) DK0512883T3 (da)
EE (1) EE03017B1 (da)
ES (1) ES2107511T3 (da)
FR (1) FR2676231A1 (da)
GR (1) GR3025134T3 (da)
IL (1) IL99567A (da)
LT (1) LT3417B (da)
RU (1) RU2097047C1 (da)
UA (1) UA27733C2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004534855A (ja) * 2001-07-20 2004-11-18 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 第ｖｉｉ因子ポリペプチドおよび第ｘｉ因子ポリペプチドを含んでなる医薬組成物
US20030040480A1 (en) * 2001-07-20 2003-02-27 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
US20050181978A1 (en) * 2003-11-20 2005-08-18 Rasmus Rojkjaer Therapeutic use of factor XI
TW200529870A (en) * 2003-11-20 2005-09-16 Novo Nordisk Healthcare Ag Therapeutic use of factor XI
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
ES2764222T3 (es) * 2006-09-08 2020-06-02 Wyeth Llc Lavado con arginina en la purificación de proteínas mediante el uso de cromatografía de afinidad
WO2008081025A1 (en) * 2007-01-04 2008-07-10 Crucell Holland B.V. Purification of factor xi
KR101979134B1 (ko) * 2008-10-15 2019-05-15 아이오니스 파마수티컬즈, 인코포레이티드 인자 １１ 발현의 조정
FR2974301B1 (fr) * 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
FR2974366B1 (fr) * 2011-04-20 2016-06-24 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur xi
IL212911A0 (en) 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
DE102012022234A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Einstufiges Verfahren zur Reinigung von (Blut)Plasmaproteinen wie Albumin aus Gemischen
DE102012022233A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Verfahren zur Reinigung eines (Blut)plasmaproteins
FR3032621A1 (fr) 2015-02-13 2016-08-19 Lab Francais Du Fractionnement Colle biologique et son utilisation comme medicament
KR101941974B1 (ko) * 2016-11-18 2019-01-24 주식회사 녹십자 혈장 단백질 정제시 fxi의 제거방법
PE20210393A1 (es) 2018-05-09 2021-03-02 Ionis Pharmaceuticals Inc Compuestos y metodos para la reduccion de la expresion de fxi

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783262A (en) 1987-03-30 1988-11-08 Cuno Incorporated Separator for cell type filter element
US4859340A (en) 1976-03-15 1989-08-22 Cuno, Incorporated Filter sheet

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859340A (en) 1976-03-15 1989-08-22 Cuno, Incorporated Filter sheet
US4783262A (en) 1987-03-30 1988-11-08 Cuno Incorporated Separator for cell type filter element

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
B. HOROWITZ PHD ET AL.: "Inactivation of viruses in labile blood derivatives. I. Disruption of lipid-enveloped viruses by tri(n-butyl)phosphate detergent combinations", TRANSFUSION, 1985, pages 516 - 522, XP002950839, DOI: doi:10.1046/j.1537-2995.1985.25686071422.x
BOUMA BN, GRIFFIN JH: "Human blood coagulation factor XI. Purification, properties, and mechanism of activation by activated factor XII", J BIOL CHEM., 1977, pages 6432 - 6437, XP002627223
KOIDE ET AL.: "Blood clotting enzymes", METHODS IN ENZYMOLOGY, 1975, pages 65 - 73
WINKELMAN ET AL.: "Internat"

Also Published As

Publication number Publication date
FR2676231A1 (fr) 1992-11-13
DE69221369D1 (de) 1997-09-11
RU2097047C1 (ru) 1997-11-27
IL99567A (en) 1996-01-19
CA2068069C (en) 2005-03-15
IL99567A0 (en) 1992-08-18
ATE156360T1 (de) 1997-08-15
US5252217A (en) 1993-10-12
GR3025134T3 (en) 1998-02-27
EE03017B1 (et) 1997-08-15
DK0512883T3 (da) 1998-03-16
ES2107511T3 (es) 1997-12-01
LTIP265A (en) 1994-10-25
DE69221369T2 (de) 1998-03-19
CA2068069A1 (en) 1992-11-08
UA27733C2 (uk) 2000-10-16
AU652043B2 (en) 1994-08-11
FR2676231B1 (da) 1995-04-21
AU1526392A (en) 1992-11-12
BR9201718A (pt) 1992-12-29
EP0512883A1 (fr) 1992-11-11
EP0512883B1 (fr) 1997-08-06

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Legal Events

Date Code Title Description
PC9A Transfer of patents

Owner name: THE LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES

Effective date: 20090511

TC9A Change of representative

Representative=s name: ZABOLIENE, REDA, LT

MM9A Lapsed patents

Effective date: 20091229