GR3025134T3 - Process for preparing a concentrate of blood coagulation factor XI with high specific activity, appropriate for therapeutic use - Google Patents

Process for preparing a concentrate of blood coagulation factor XI with high specific activity, appropriate for therapeutic use

Info

Publication number
GR3025134T3
GR3025134T3 GR970402766T GR970402766T GR3025134T3 GR 3025134 T3 GR3025134 T3 GR 3025134T3 GR 970402766 T GR970402766 T GR 970402766T GR 970402766 T GR970402766 T GR 970402766T GR 3025134 T3 GR3025134 T3 GR 3025134T3
Authority
GR
Greece
Prior art keywords
concentrate
specific activity
high specific
therapeutic use
preparing
Prior art date
Application number
GR970402766T
Other languages
English (en)
Inventor
Nee Radosevich Miryana Burnouf
Dominique Dernis
Original Assignee
Aetsrn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aetsrn filed Critical Aetsrn
Publication of GR3025134T3 publication Critical patent/GR3025134T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6443—Coagulation factor XIa (3.4.21.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21027—Coagulation factor XIa (3.4.21.27)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
GR970402766T 1991-05-07 1997-10-22 Process for preparing a concentrate of blood coagulation factor XI with high specific activity, appropriate for therapeutic use GR3025134T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9105572A FR2676231A1 (fr) 1991-05-07 1991-05-07 Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.

Publications (1)

Publication Number Publication Date
GR3025134T3 true GR3025134T3 (en) 1998-02-27

Family

ID=9412593

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970402766T GR3025134T3 (en) 1991-05-07 1997-10-22 Process for preparing a concentrate of blood coagulation factor XI with high specific activity, appropriate for therapeutic use

Country Status (16)

Country Link
US (1) US5252217A (el)
EP (1) EP0512883B1 (el)
AT (1) ATE156360T1 (el)
AU (1) AU652043B2 (el)
BR (1) BR9201718A (el)
CA (1) CA2068069C (el)
DE (1) DE69221369T2 (el)
DK (1) DK0512883T3 (el)
EE (1) EE03017B1 (el)
ES (1) ES2107511T3 (el)
FR (1) FR2676231A1 (el)
GR (1) GR3025134T3 (el)
IL (1) IL99567A (el)
LT (1) LT3417B (el)
RU (1) RU2097047C1 (el)
UA (1) UA27733C2 (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030040480A1 (en) * 2001-07-20 2003-02-27 Rasmus Rojkjaer Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides
KR20040015821A (ko) * 2001-07-20 2004-02-19 노보 노르디스크 헬스 케어 악티엔게젤샤프트 인자 ⅶ 폴리펩티드와 인자 ⅹⅰ폴리펩티드를 포함하는약학적 조성물
US20050181978A1 (en) * 2003-11-20 2005-08-18 Rasmus Rojkjaer Therapeutic use of factor XI
WO2005049070A1 (en) * 2003-11-20 2005-06-02 Novo Nordisk Health Care Ag Therapeutic use of factor xi
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
AR062711A1 (es) * 2006-09-08 2008-11-26 Wyeth Corp Lavado de arginina en l a purificacion de proteinas usando cromatografia de afinidad
ATE546520T1 (de) * 2007-01-04 2012-03-15 Crucell Holland Bv Faktor-xi-reinigung
ES2657679T3 (es) 2008-10-15 2018-03-06 Ionis Pharmaceuticals, Inc. Modulación del factor de expresión 11
FR2974366B1 (fr) 2011-04-20 2016-06-24 Lab Francais Du Fractionnement Procede de preparation d'un concentre de facteur xi
FR2974301B1 (fr) * 2011-04-20 2013-08-23 Lab Francais Du Fractionnement Procede de preparation d'un produit plasmatique deplete en un ou plusieurs facteurs thrombogenes
IL212911A0 (en) 2011-05-16 2011-07-31 Omrix Biopharmaceuticals Ltd Immunoglobulin reduced in thrombogenic contaminants and preparation thereof
DE102012022234A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Einstufiges Verfahren zur Reinigung von (Blut)Plasmaproteinen wie Albumin aus Gemischen
DE102012022233A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Verfahren zur Reinigung eines (Blut)plasmaproteins
FR3032621A1 (fr) 2015-02-13 2016-08-19 Lab Francais Du Fractionnement Colle biologique et son utilisation comme medicament
KR101941974B1 (ko) * 2016-11-18 2019-01-24 주식회사 녹십자 혈장 단백질 정제시 fxi의 제거방법
EP3799604A4 (en) 2018-05-09 2022-09-07 Ionis Pharmaceuticals, Inc. COMPOUNDS AND METHODS FOR REDUCING FXI EXPRESSION

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4859340A (en) * 1976-03-15 1989-08-22 Cuno, Incorporated Filter sheet
US4783262A (en) * 1987-03-30 1988-11-08 Cuno Incorporated Separator for cell type filter element

Also Published As

Publication number Publication date
AU652043B2 (en) 1994-08-11
FR2676231A1 (fr) 1992-11-13
IL99567A0 (en) 1992-08-18
BR9201718A (pt) 1992-12-29
CA2068069C (en) 2005-03-15
DK0512883T3 (da) 1998-03-16
LT3417B (en) 1995-09-25
ES2107511T3 (es) 1997-12-01
EP0512883B1 (fr) 1997-08-06
CA2068069A1 (en) 1992-11-08
FR2676231B1 (el) 1995-04-21
AU1526392A (en) 1992-11-12
EP0512883A1 (fr) 1992-11-11
DE69221369D1 (de) 1997-09-11
LTIP265A (en) 1994-10-25
RU2097047C1 (ru) 1997-11-27
UA27733C2 (uk) 2000-10-16
US5252217A (en) 1993-10-12
ATE156360T1 (de) 1997-08-15
EE03017B1 (et) 1997-08-15
IL99567A (en) 1996-01-19
DE69221369T2 (de) 1998-03-19

Similar Documents

Publication Publication Date Title
GR3025134T3 (en) Process for preparing a concentrate of blood coagulation factor XI with high specific activity, appropriate for therapeutic use
ES2077530A1 (es) Procedimiento para la preparacion de productos farmaceuticos para curar enfermedades tumorales.
PL319370A1 (en) Application of photodynamic therapy for selectively inactivating blood cells and treatment o diseases associated with immunological disturbances
ZA896463B (en) Thrombus control agent
AU582972B2 (en) Lipoprotein adsorbent for use in extracorporeal circulation treatment and process for preparing thereof
AU7426487A (en) Method of treating depression using d-fenfluramine
PT86205A (en) Process for the preparation of 3-]omega-(3,5-di-t-butil-4-hydroxyphenyl)-alkanoyl"pyrroles and their de-oxy analogs useful in therapy
CA2011992A1 (en) Use of human interferon-beta for stimulation of erythropoiesis
AU584548B2 (en) Sterilization of adsorbent and column having improved storability including sterilized adsorbent for use in extracorporeal circulation treatment
DE3572441D1 (en) Use of interferon gamma (ifn-gamma) for the production of preparations for treating rheumatic diseases
ZA849576B (en) 1,7-diphenyl-3-methyllaza-7-cyano-8-methylnonane for use in the treatment of diseases
GB2314271A (en) Therapeutic methods and preparations using rubidium ions
EP0212310A3 (en) Use of probucol in the preparation of a medicament for the treatment of heart arrhythmia
ES8404693A1 (es) Procedimiento de preparacion de nuevos amino-14 esteroides.
AU7633987A (en) The use of 15-deoxyspergualine as a pharmaceutical
USD298170S (en) Table for massaging and chiropractic therapy
ZA86101B (en) Process for recovering absorbent for use in extracorporeal circulation treatment
DE3476736D1 (en) Use of an antihypoxidoticum with cerebral and peripheral effect
HU900381D0 (en) Process for producing medical preparatives utilizable for treating cancerous diseases
GR3005378T3 (el)
IT1247488B (it) Uso del pirrolidoncarbossilato di piridossina per il trattamento dei disturbi affettivi depressivi
AU99667S (en) Physical therapy treatment table
ZA868404B (en) Pharmaceutical compositions for use in improving oxygenation of the brain and a process for their production
PL271057A1 (en) Method of making therapeutic cream for treatment of dermatopathies, in particular burns
GB8817446D0 (en) Treatment of various blood disorders