ATE546520T1 - Faktor-xi-reinigung - Google Patents

Faktor-xi-reinigung

Info

Publication number
ATE546520T1
ATE546520T1 AT08701217T AT08701217T ATE546520T1 AT E546520 T1 ATE546520 T1 AT E546520T1 AT 08701217 T AT08701217 T AT 08701217T AT 08701217 T AT08701217 T AT 08701217T AT E546520 T1 ATE546520 T1 AT E546520T1
Authority
AT
Austria
Prior art keywords
factor
cleaning
methods
hcic
blood coagulation
Prior art date
Application number
AT08701217T
Other languages
English (en)
Inventor
Paul Henri Markus
Original Assignee
Crucell Holland Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv
Application granted granted Critical
Publication of ATE546520T1 publication Critical patent/ATE546520T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6443—Coagulation factor XIa (3.4.21.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21027—Coagulation factor XIa (3.4.21.27)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT08701217T 2007-01-04 2008-01-03 Faktor-xi-reinigung ATE546520T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87850907P 2007-01-04 2007-01-04
EP07100123 2007-01-04
PCT/EP2008/050035 WO2008081025A1 (en) 2007-01-04 2008-01-03 Purification of factor xi

Publications (1)

Publication Number Publication Date
ATE546520T1 true ATE546520T1 (de) 2012-03-15

Family

ID=38038498

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08701217T ATE546520T1 (de) 2007-01-04 2008-01-03 Faktor-xi-reinigung

Country Status (5)

Country Link
US (1) US20100062512A1 (de)
EP (1) EP2102335B1 (de)
AT (1) ATE546520T1 (de)
DK (1) DK2102335T3 (de)
WO (1) WO2008081025A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102216449B (zh) * 2008-07-15 2013-03-06 克鲁塞尔荷兰公司 用于培养per.c6细胞以及从中生产产物的可规模化的方法
SE1050124A1 (sv) 2010-02-08 2011-08-09 Linkoping Biocontrols Ab Stabil lösning
DK2552948T3 (en) 2010-03-30 2016-10-17 Octapharma Ag A process for the purification of the protein growth factor G-CSF
KR20130124507A (ko) * 2010-11-16 2013-11-14 옥타파마 아게 응고 인자 ＦＸＩ 및 ＦＸＩａ를 함유한 용액으로부터 ＦＸＩ 및 ＦＸＩａ를 감소시키고 및/또는 제거하는 방법
DE102012022234A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Einstufiges Verfahren zur Reinigung von (Blut)Plasmaproteinen wie Albumin aus Gemischen
DE102012022233A1 (de) 2012-11-14 2014-05-15 Instraction Gmbh Verfahren zur Reinigung eines (Blut)plasmaproteins
US10188965B2 (en) 2012-12-05 2019-01-29 Csl Behring Gmbh Hydrophobic charge induction chromatographic depletion of a protein from a solution
US20140154233A1 (en) * 2012-12-05 2014-06-05 Csl Limited Method of purifying therapeutic proteins

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676231A1 (fr) * 1991-05-07 1992-11-13 Aetsrn Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.
CA2315143A1 (en) * 1997-10-23 1999-04-29 Fujimori Kogyo Co., Ltd. Method for refinement or method for elimination of thrombin substrate
US7138262B1 (en) * 2000-08-18 2006-11-21 Shire Human Genetic Therapies, Inc. High mannose proteins and methods of making high mannose proteins
TWI319007B (en) * 2002-11-06 2010-01-01 Novozymes As Subtilase variants
EP1869067A1 (de) * 2005-04-11 2007-12-26 Medarex, Inc. Proteinreinigung mittels hcic und ionenaustauschchromatographie

Also Published As

Publication number Publication date
WO2008081025A1 (en) 2008-07-10
EP2102335B1 (de) 2012-02-22
US20100062512A1 (en) 2010-03-11
EP2102335A1 (de) 2009-09-23
DK2102335T3 (da) 2012-05-07

Similar Documents

Publication Publication Date Title
LTPA2020536I1 (lt) Nauji anti-CD38 antikūnai, skirti vėžio gydymui
IL284991A (en) Antibodies against cd38 for treatment of multiple myeloma
ATE546520T1 (de) Faktor-xi-reinigung
SMP200900085B (it) 3-imidazolil-indoli per il trattamento di malattieproliferative.
EA200971077A1 (ru) Гетероциклические модуляторы киназы
CY1118343T1 (el) Αντισωματα συνδεσης twεακ
DK1765391T3 (da) Bakterielle præparater til behandlingen af cancer
IS2994B (is) Fosfónöt, monofosfónamidöt, bisfosfónamidöt til meðhöndlunar á veirusjúkdómum
EA200900781A1 (ru) 4-фенилпиран-3,5-дионы, 4-фенилтиопиран-3,5-дионы и циклогексантрионы, как новые гербициды
EP1960016A4 (de) Verfahren zur extrakorporalen entfernung einer pathogenen mikrobe, entzündungszelle oder eines entzündungsproteins aus blut
HRP20181727T1 (hr) Upotreba protutijela protiv čimbenika xi, namijenjena sprečavanju ili liječenju stvaranja krvnog ugruška
EP1880313A4 (de) Abnehmbarer blutgerinnselfilter
EP2136861A4 (de) Blutpumpensystem
EP1961382A4 (de) Bluttestgerät
DK3056568T3 (da) Fremgangsmåder til kontrollering af antistoffers blodfarmakokinetik
TW200740844A (en) Novel MAdCAM antibodies
EA201000903A1 (ru) Антитела к pcrv-антигену pseudomonas aeruginosa
WO2011091308A3 (en) Pipette tips
EA201000258A1 (ru) Новые гербициды
DK2117565T3 (da) Anvendelse af chitosaner til behandlingen af negleinflammatoriske sygdomme
EA200900261A1 (ru) Применение эсцина
ITMI20040648A1 (it) Procedimento per il trattamento di fluidi provenienti da giacimenti petroliferi sottomarini
NL1028599A1 (nl) Verbindingen voor de behandeling van ziekten.
BRPI0717644A2 (pt) Método de operação de peça manual oftálmica com extremidade descartável.
EA201000069A1 (ru) Новые гербициды