KR960022492A - N-보호 아미노산 에스테르로부터 n-보호 아미노산 알파-할로메틸케톤 및 알코올의 제조방법 - Google Patents

N-보호 아미노산 에스테르로부터 n-보호 아미노산 알파-할로메틸케톤 및 알코올의 제조방법 Download PDF

Info

Publication number
KR960022492A
KR960022492A KR1019950048318A KR19950048318A KR960022492A KR 960022492 A KR960022492 A KR 960022492A KR 1019950048318 A KR1019950048318 A KR 1019950048318A KR 19950048318 A KR19950048318 A KR 19950048318A KR 960022492 A KR960022492 A KR 960022492A
Authority
KR
South Korea
Prior art keywords
compound
formula
process according
xiii
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019950048318A
Other languages
English (en)
Korean (ko)
Inventor
첸 핑
타이 와 쳉 피터
에이치. 스페르걸 스티븐
씨. 바리쉬 조엘
케이. 도타딜 존
잘러 로버트
피. 폴니아스젝 리차드
왕 쿠에바오
Original Assignee
니콜라스 피. 말라테스티닠
브리스톨-마이어즈 스퀴브 컴페니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 니콜라스 피. 말라테스티닠, 브리스톨-마이어즈 스퀴브 컴페니 filed Critical 니콜라스 피. 말라테스티닠
Publication of KR960022492A publication Critical patent/KR960022492A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1019950048318A 1994-12-13 1995-12-11 N-보호 아미노산 에스테르로부터 n-보호 아미노산 알파-할로메틸케톤 및 알코올의 제조방법 Withdrawn KR960022492A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/355,373 US5481011A (en) 1994-12-13 1994-12-13 Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters
US355,373 1994-12-13

Publications (1)

Publication Number Publication Date
KR960022492A true KR960022492A (ko) 1996-07-18

Family

ID=23397213

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950048318A Withdrawn KR960022492A (ko) 1994-12-13 1995-12-11 N-보호 아미노산 에스테르로부터 n-보호 아미노산 알파-할로메틸케톤 및 알코올의 제조방법

Country Status (11)

Country Link
US (1) US5481011A (enExample)
EP (1) EP0719769A2 (enExample)
JP (1) JPH08225557A (enExample)
KR (1) KR960022492A (enExample)
CN (1) CN1132203A (enExample)
AU (1) AU690768B2 (enExample)
CA (1) CA2163062C (enExample)
FI (1) FI955955A7 (enExample)
HU (1) HU215249B (enExample)
IL (1) IL116319A0 (enExample)
TW (1) TW365605B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101299972B1 (ko) * 2011-03-30 2013-08-26 순천향대학교 산학협력단 수소화붕소나트륨을 이용한 (3Ｓ)-3-(ｔｅｒｔ-부톡시카르보닐)아미노-1-클로로-4-페닐-(2Ｓ)-부탄올의 제조방법

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100411856B1 (ko) * 1995-02-03 2004-05-20 카네카 코포레이션 α-할로케톤,α-할로히드린및에폭사이드의제조법
USH1893H (en) * 1996-07-23 2000-10-03 Bristol-Myers Squibb Company Enzymatic reduction method for the preparation of halohydrins
CA2319088A1 (en) * 1998-01-28 1999-08-05 Nippon Kayaku Kabushiki Kaisha Process for producing optically active threo-3-amino-1,2-epoxy compounds
DE60005304T2 (de) * 1999-01-21 2004-06-24 Kaneka Corp. Methode zur reinigung und abtrennung von (2s,3s)- oder (2r,3s)-halohydrinderivaten
CA2361475A1 (en) * 1999-01-28 2000-08-03 Ajinomoto Co., Inc. Process for the preparation of .alpha.-aminoketones
EP1661893A3 (en) * 1999-01-29 2006-06-07 Kaneka Corporation Process for the preparation of threo-1,2-epoxy-3-amino-4-phenylbutane derivatives
US6605732B1 (en) * 1999-05-03 2003-08-12 Aerojet Fine Chemicals Llc Clean, high-yield preparation of S,S and R,S amino acid isosteres
KR100339831B1 (ko) * 1999-08-18 2002-06-07 김태성 신규의 에틸 아지리딘 유도체 및 그 제조방법
KR100708221B1 (ko) * 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법
US6992081B2 (en) 2000-03-23 2006-01-31 Elan Pharmaceuticals, Inc. Compounds to treat Alzheimer's disease
ATE343562T1 (de) 2000-03-23 2006-11-15 Elan Pharm Inc Verbindungen und verfahren zur behandlung der alzheimerschen krankheit
CN1217920C (zh) * 2000-06-30 2005-09-07 艾兰制药公司 治疗早老性痴呆的化合物
EP1666452A2 (en) 2000-06-30 2006-06-07 Elan Pharmaceuticals, Inc. Compounds to treat Alzheimer's disease
US20030096864A1 (en) * 2000-06-30 2003-05-22 Fang Lawrence Y. Compounds to treat alzheimer's disease
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
US7253194B2 (en) * 2000-07-24 2007-08-07 The University Of Queensland Compounds and inhibitors of phospholipases
US7122696B2 (en) * 2000-11-30 2006-10-17 Ajinomoto Co., Inc. Processes for preparation of N-protected-β-amino alcohols and N-protected-β-amino epoxides
KR20020046948A (ko) 2000-12-12 2002-06-21 에가시라 구니오 에폭사이드 결정의 제조방법
AR035960A1 (es) * 2001-04-23 2004-07-28 Elan Pharm Inc Epoxidos sustituidos y procesos para prepararlos
MXPA04000140A (es) * 2001-06-27 2004-06-03 Elan Pharm Inc Derivados de beta-hidroxiamina utiles en el tratamiento de enfermedad de alzheimer.
DE10143742A1 (de) 2001-09-06 2003-03-27 Consortium Elektrochem Ind Verfahren zur Herstellung von alpha-Halogenketonen
GB0417824D0 (en) * 2004-08-11 2004-09-15 Phoenix Chemicals Ltd Process for asymmetric catalytic hydrogenation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1290787A (enExample) * 1970-03-12 1972-09-27
GB1335317A (en) * 1971-06-23 1973-10-24 Leo Pharm Prod Ltd Cephalosporin esters salts thereof and methods for their pre paration
JPS53124226A (en) * 1977-04-07 1978-10-30 Mitsubishi Gas Chem Co Inc Preparation of polyglycidyl compounds
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
DD295369A5 (de) * 1988-10-06 1991-10-31 Tech Hochschule C Schorlemmer Verfahren zur herstellung von substituierten glycidylanilinen
ATE141265T1 (de) * 1992-05-20 1996-08-15 Searle & Co Verfahren zur herstellung von intermediaten in der synthese von retroviralen protease inhibitoren
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101299972B1 (ko) * 2011-03-30 2013-08-26 순천향대학교 산학협력단 수소화붕소나트륨을 이용한 (3Ｓ)-3-(ｔｅｒｔ-부톡시카르보닐)아미노-1-클로로-4-페닐-(2Ｓ)-부탄올의 제조방법

Also Published As

Publication number Publication date
AU4036095A (en) 1996-06-20
FI955955A0 (fi) 1995-12-12
HUT73644A (en) 1996-09-30
FI955955L (fi) 1996-06-14
EP0719769A3 (enExample) 1996-07-31
TW365605B (en) 1999-08-01
CA2163062C (en) 1999-02-09
FI955955A7 (fi) 1996-06-14
IL116319A0 (en) 1996-03-31
HU9503544D0 (en) 1996-02-28
US5481011A (en) 1996-01-02
HU215249B (hu) 1998-11-30
CA2163062A1 (en) 1996-06-14
EP0719769A2 (en) 1996-07-03
JPH08225557A (ja) 1996-09-03
AU690768B2 (en) 1998-04-30
CN1132203A (zh) 1996-10-02

Similar Documents

Publication Publication Date Title
KR960022492A (ko) N-보호 아미노산 에스테르로부터 n-보호 아미노산 알파-할로메틸케톤 및 알코올의 제조방법
KR840002400A (ko) 7-옥사비시클로헵탄 및 7-옥사비시클로헵텐 프로스타글라딘 동족체의 제조방법
CA1167464A (en) Process for producing threo-3-amino-2-hydroxybutanoyl- aminoacetic acids, as well as novel intermediates therefor and process for producing them
ATE309233T1 (de) Verfahren zur herstellung eines epoxids
KR960034176A (ko) ε-카프로락탐 및 ε-카프로락탐 전구체의 제조방법
KR950701902A (ko) 리그난계 화합물의 제조방법(process for producing lignan compound)
KR840008346A (ko) 축합 7원 고리 화합물의 제조방법
TW339326B (en) Process for the prepration of lactams
US5684176A (en) Process for manufacturing an α, α'-diaminoalcohol
KR840001575A (ko) 면역 조절작용을 가진 화합물의 제조방법
DE69524578D1 (de) Verfahren zur herstellung von epoxiden
DE69903799D1 (de) Verfahren zu erzeugung von simvastatin und/oder deren derivaten
GR3034751T3 (en) A process for the preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines.
KR840001581A (ko) 베타-락타마제 억제제 2-베타-치환-2-알파-메틸-(5r)펜임-3-알파카복실산 1,1-디옥사이드 및 그 중간체의 제조방법
RU2003128953A (ru) Деградация эпотилонов
KR950005793A (ko) 광학활성 2- 노르보르난온의 제조방법
BG103328A (en) Method for the preparation of n-[2-(dimethylamino)ethyl]-acridine-4-carboxamide
EP0784608B1 (en) The manufacture of levobupivacaine and analogues thereof from l-lysine
MY112291A (en) Preparation of cyclic lactams
JPS647973B2 (enExample)
KR970015583A (ko) (S) -β-하이드록시-γ-부티로락톤의 제조방법
ATE18206T1 (de) Verfahren zur herstellung eines laktams.
KR970042482A (ko) 3차 아민의 제조방법
ATE155125T1 (de) Herstellung von dobutamin verbindungen
KR100469947B1 (ko) 키랄(s)-3-아미노-1,2-프로판디올의제조방법

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19951211

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid