KR970042482A - 3차 아민의 제조방법 - Google Patents

3차 아민의 제조방법 Download PDF

Info

Publication number
KR970042482A
KR970042482A KR1019950059739A KR19950059739A KR970042482A KR 970042482 A KR970042482 A KR 970042482A KR 1019950059739 A KR1019950059739 A KR 1019950059739A KR 19950059739 A KR19950059739 A KR 19950059739A KR 970042482 A KR970042482 A KR 970042482A
Authority
KR
South Korea
Prior art keywords
tertiary amine
metal catalyst
prepared
following formula
dicarboxylic acid
Prior art date
Application number
KR1019950059739A
Other languages
English (en)
Other versions
KR100352551B1 (ko
Inventor
백성인
최태근
Original Assignee
이웅열
주식회사 코오롱
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 이웅열, 주식회사 코오롱 filed Critical 이웅열
Priority to KR1019950059739A priority Critical patent/KR100352551B1/ko
Publication of KR970042482A publication Critical patent/KR970042482A/ko
Application granted granted Critical
Publication of KR100352551B1 publication Critical patent/KR100352551B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/50—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2523/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00
    • C07C2523/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals
    • C07C2523/40—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group C07C2521/00 of noble metals of the platinum group metals
    • C07C2523/44—Palladium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

본 발명은 다음 구조식 (2)의 디카르본산 유도체와 디메틸아민(3)을 반응시켜 생성되는 디아미드(4)를 금속 촉매하 직접 수소화반응으로 환원하여 다음 구조식 (1)의 3차 아민을 제조하는 방법을 제공한다.
[M]
H2OC-X-CO2H + HN(CH3)2----- 〉 (H3C)2NOC-X-CON(CH3)2-------- 〉
(2) (3) (4) H2
(1)
상기식에서, X는 알킬렌기를 나타내며, [M]은 금속촉매를 나타낸다. 본 발명의 방법에 따라, 보다 경제적으로 간단하게 고수율, 고순도로 상기 구조식 (1)의 3차 아민 유도체를 제조할 수 있다.

Description

3차 아민의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 다음 구조식 (2)의 디카르본산 유도체와 디메틸아민(3)을 반응시켜 생성되는 디아미드(4)를 금속촉매하 직접 수소화반응으로 환원하여 다음 구조식 (1)의 3차 아민을 제조하는 방법.
    [M]
    H2OC-X-CO2H + HN(CH3)2----- 〉 (H3C)2NOC-X-CON(CH3)2-------- 〉
    (2) (3) (4) H2
    (1)
    상기식에서, X는 알킬렌기를 나타내며, [M]은 금속촉매를 나타낸다.
  2. 제 1항에 있어서, 금속촉매로서 Pd/C를 디카르본산의 몰수 기준으로 0.01-1.0몰%를 사용하여 3차 아민을 제조하는 방법.
  3. 제 1항에 있어서, 수소화반응시 반응온도를 150-200℃로하여 3차아민을 제조하는 방법.
  4. 4. 제 1항에 있어서, 기체상태의 디메틸아민을 사용하여 3차 아민을 제조하는 방법.
KR1019950059739A 1995-12-27 1995-12-27 3차아민의제조방법 KR100352551B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019950059739A KR100352551B1 (ko) 1995-12-27 1995-12-27 3차아민의제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950059739A KR100352551B1 (ko) 1995-12-27 1995-12-27 3차아민의제조방법

Publications (2)

Publication Number Publication Date
KR970042482A true KR970042482A (ko) 1997-07-24
KR100352551B1 KR100352551B1 (ko) 2003-04-21

Family

ID=37489210

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950059739A KR100352551B1 (ko) 1995-12-27 1995-12-27 3차아민의제조방법

Country Status (1)

Country Link
KR (1) KR100352551B1 (ko)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1272135A (fr) * 1960-08-10 1961-09-22 Commissariat Energie Atomique Perfectionnements apportés aux procédés pour la préparation des amines tertiaires
JPS6172734A (ja) * 1984-09-19 1986-04-14 Nippon Oil & Fats Co Ltd 第三アミンの製造方法
JPS6115865A (ja) * 1984-06-29 1986-01-23 Kao Corp 第３級アミンの製造方法
JPS62252746A (ja) * 1986-04-24 1987-11-04 Mitsubishi Chem Ind Ltd ３級アミンの製造方法
JPH0791238B2 (ja) * 1993-02-15 1995-10-04 花王株式会社 第３級アミンの製造方法
KR960000854A (ko) * 1994-06-30 1996-01-25 하기주 3차아민의 제조방법

Also Published As

Publication number Publication date
KR100352551B1 (ko) 2003-04-21

Similar Documents

Publication Publication Date Title
KR960022492A (ko) N-보호 아미노산 에스테르로부터 n-보호 아미노산 알파-할로메틸케톤 및 알코올의 제조방법
MY110410A (en) New finasteride processes
KR20040075884A (ko) 할로겐화알킬을 사용한 3차 아민의 연속 4차화 방법
US4321411A (en) Process for producing N-substituted acrylamide or methacrylamide
KR970042482A (ko) 3차 아민의 제조방법
US5371289A (en) Preparation of N-substituted-N'-phenyl p-phenylenediamines
MX9602756A (es) Nuevo procedimiento de alta selectividad enantiomerica para la produccion de ciclopentano- y - penteno-beta-aminoacidos enantiomericamente puros.
KR900018220A (ko) 폴리말레이미드화합물 및 그 제조방법
US4539403A (en) Process for the preparation of a 2-alkyl-4-amino-5-aminomethylpyrimidine
KR20020067575A (ko) Ｎ-메틸-ｎ＇-니트로구아니딘의 제조방법
US5099067A (en) Use of ammonium formate as a hydrogen transfer reagent for reduction of chiral nitro compounds with retention of configuration
EP0427197B1 (en) Process for the production of vinyl-GABA
KR970042490A (ko) 시클로프로판카르복실산 아미드의 제조방법
EP0619294A4 (en) PROCESS FOR THE PRODUCTION OF 1-PHENOXY-2-AMINOPROPANE.
US5118846A (en) Synthesis of N-disubstituted amides by reaction of amides with certain organic hydroxyl compounds
IL119258A (en) Process for the preparation of alkaline esters of 2-nitro-5-chlorophenyl acetic acid
KR920006319A (ko) N-(2-클로로-피리딘-5-일-메틸)-에틸렌디아민의 제조방법
KR960017633A (ko) 4-아미노페닐-2-아세톡시에틸설폰의 제조방법
KR970015583A (ko) (S) -β-하이드록시-γ-부티로락톤의 제조방법
KR900001197B1 (ko) 2-알킬-4-아미노-5-아미노메틸피리미딘의 제조방법
US5475140A (en) Process for producing N,N-disubstituted p-phenylenediamine derivative sulfate
US3651137A (en) Selective conversion of nalpha nepsilon-diacetyllysine esters to nalpha -diacetyllysine
KR930019601A (ko) 4-히드록시 만델산의 제조방법
KR890003286B1 (ko) N-치환 글라이신의 제조방법
CA2166090A1 (en) Novel process for preparing 17.beta.-substituted 4-azaandrostane derivatives

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee