IL116319A0 - Process for preparing n-protected amino acid alpha-halomethyl ketones and alcohols from n-protected amino acid esters - Google Patents

Process for preparing n-protected amino acid alpha-halomethyl ketones and alcohols from n-protected amino acid esters

Info

Publication number
IL116319A0
IL116319A0 IL11631995A IL11631995A IL116319A0 IL 116319 A0 IL116319 A0 IL 116319A0 IL 11631995 A IL11631995 A IL 11631995A IL 11631995 A IL11631995 A IL 11631995A IL 116319 A0 IL116319 A0 IL 116319A0
Authority
IL
Israel
Prior art keywords
amino acid
protected amino
alcohols
preparing
acid esters
Prior art date
Application number
IL11631995A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of IL116319A0 publication Critical patent/IL116319A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL11631995A 1994-12-13 1995-12-10 Process for preparing n-protected amino acid alpha-halomethyl ketones and alcohols from n-protected amino acid esters IL116319A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/355,373 US5481011A (en) 1994-12-13 1994-12-13 Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters

Publications (1)

Publication Number Publication Date
IL116319A0 true IL116319A0 (en) 1996-03-31

Family

ID=23397213

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11631995A IL116319A0 (en) 1994-12-13 1995-12-10 Process for preparing n-protected amino acid alpha-halomethyl ketones and alcohols from n-protected amino acid esters

Country Status (11)

Country Link
US (1) US5481011A (enExample)
EP (1) EP0719769A2 (enExample)
JP (1) JPH08225557A (enExample)
KR (1) KR960022492A (enExample)
CN (1) CN1132203A (enExample)
AU (1) AU690768B2 (enExample)
CA (1) CA2163062C (enExample)
FI (1) FI955955A7 (enExample)
HU (1) HU215249B (enExample)
IL (1) IL116319A0 (enExample)
TW (1) TW365605B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0754669B1 (en) * 1995-02-03 2001-10-31 Kaneka Corporation Processes for producing alpha-halo ketones, alpha-halohydrins and epoxides
USH1893H (en) * 1996-07-23 2000-10-03 Bristol-Myers Squibb Company Enzymatic reduction method for the preparation of halohydrins
DE69916030T2 (de) 1998-01-28 2004-08-05 Nippon Kayaku K.K. Verfahren zur herstellung optisch aktiver threo-3-amino-1,2-epoxyverbindungen
EP1151992B1 (en) * 1999-01-21 2003-09-17 Kaneka Corporation Method for purifying and isolating (2s,3s)- or (2r,3s)-halohydrin derivatives
WO2000044706A1 (en) 1999-01-28 2000-08-03 Ajinomoto Co., Inc. PROCESS FOR THE PREPARATION OF α-AMINOKETONES
CA2325919C (en) * 1999-01-29 2009-07-21 Kaneka Corporation Processes for the preparation of threo-1,2-epoxy-3-amino-4-phenylbutane derivatives
US6605732B1 (en) * 1999-05-03 2003-08-12 Aerojet Fine Chemicals Llc Clean, high-yield preparation of S,S and R,S amino acid isosteres
KR100339831B1 (ko) * 1999-08-18 2002-06-07 김태성 신규의 에틸 아지리딘 유도체 및 그 제조방법
KR100708221B1 (ko) * 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법
AU2001252958A1 (en) * 2000-03-23 2001-10-03 Elan Pharmaceuticals, Inc. Compounds and methods to treat alzheimer's disease
US6992081B2 (en) 2000-03-23 2006-01-31 Elan Pharmaceuticals, Inc. Compounds to treat Alzheimer's disease
US20030096864A1 (en) * 2000-06-30 2003-05-22 Fang Lawrence Y. Compounds to treat alzheimer's disease
CA2410680A1 (en) * 2000-06-30 2002-01-10 Elan Pharmaceuticals, Inc. Compounds to treat alzheimer's disease
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
US6846813B2 (en) * 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
EP1666452A2 (en) 2000-06-30 2006-06-07 Elan Pharmaceuticals, Inc. Compounds to treat Alzheimer's disease
WO2002008189A1 (en) * 2000-07-24 2002-01-31 The University Of Queensland Compounds and inhibitors of phospholipases
JPWO2002044136A1 (ja) * 2000-11-30 2004-04-02 味の素株式会社 N保護−β−アミノアルコールの製造法およびN保護−β−アミノエポキシドの製造法
US6764545B2 (en) 2000-12-12 2004-07-20 Ajinomoto Co., Inc. Production method of epoxide crystal
AR035960A1 (es) * 2001-04-23 2004-07-28 Elan Pharm Inc Epoxidos sustituidos y procesos para prepararlos
CA2452039A1 (en) * 2001-06-27 2003-01-09 Elan Pharmaceuticals, Inc. Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease
DE10143742A1 (de) 2001-09-06 2003-03-27 Consortium Elektrochem Ind Verfahren zur Herstellung von alpha-Halogenketonen
GB0417824D0 (en) * 2004-08-11 2004-09-15 Phoenix Chemicals Ltd Process for asymmetric catalytic hydrogenation
KR101299972B1 (ko) * 2011-03-30 2013-08-26 순천향대학교 산학협력단 수소화붕소나트륨을 이용한 (3S)-3-(tert-부톡시카르보닐)아미노-1-클로로-4-페닐-(2S)-부탄올의 제조방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1290787A (enExample) * 1970-03-12 1972-09-27
GB1335317A (en) * 1971-06-23 1973-10-24 Leo Pharm Prod Ltd Cephalosporin esters salts thereof and methods for their pre paration
JPS53124226A (en) * 1977-04-07 1978-10-30 Mitsubishi Gas Chem Co Inc Preparation of polyglycidyl compounds
CA1340588C (en) * 1988-06-13 1999-06-08 Balraj Krishan Handa Amino acid derivatives
DD295369A5 (de) * 1988-10-06 1991-10-31 Tech Hochschule C Schorlemmer Verfahren zur herstellung von substituierten glycidylanilinen
WO1993023388A1 (en) * 1992-05-20 1993-11-25 G.D. Searle & Co. Method for making intermediates useful in synthesis of retroviral protease inhibitors
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors

Also Published As

Publication number Publication date
AU4036095A (en) 1996-06-20
CN1132203A (zh) 1996-10-02
EP0719769A2 (en) 1996-07-03
HU215249B (hu) 1998-11-30
TW365605B (en) 1999-08-01
JPH08225557A (ja) 1996-09-03
FI955955L (fi) 1996-06-14
CA2163062C (en) 1999-02-09
US5481011A (en) 1996-01-02
KR960022492A (ko) 1996-07-18
FI955955A7 (fi) 1996-06-14
CA2163062A1 (en) 1996-06-14
FI955955A0 (fi) 1995-12-12
AU690768B2 (en) 1998-04-30
EP0719769A3 (enExample) 1996-07-31
HU9503544D0 (en) 1996-02-28
HUT73644A (en) 1996-09-30

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