HU215249B - Eljárás N-védett amino-epoxid vegyületek N-védett aminosav-észterekből történő előállítására - Google Patents
Eljárás N-védett amino-epoxid vegyületek N-védett aminosav-észterekből történő előállítására Download PDFInfo
- Publication number
- HU215249B HU215249B HU9503544A HU9503544A HU215249B HU 215249 B HU215249 B HU 215249B HU 9503544 A HU9503544 A HU 9503544A HU 9503544 A HU9503544 A HU 9503544A HU 215249 B HU215249 B HU 215249B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- compound
- process according
- solution
- reducing agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/355,373 US5481011A (en) | 1994-12-13 | 1994-12-13 | Process for preparing N-protected amino acid α-halomethyl ketones and alcohols from N-protected amino acid esters |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9503544D0 HU9503544D0 (en) | 1996-02-28 |
| HUT73644A HUT73644A (en) | 1996-09-30 |
| HU215249B true HU215249B (hu) | 1998-11-30 |
Family
ID=23397213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9503544A HU215249B (hu) | 1994-12-13 | 1995-12-12 | Eljárás N-védett amino-epoxid vegyületek N-védett aminosav-észterekből történő előállítására |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5481011A (enExample) |
| EP (1) | EP0719769A2 (enExample) |
| JP (1) | JPH08225557A (enExample) |
| KR (1) | KR960022492A (enExample) |
| CN (1) | CN1132203A (enExample) |
| AU (1) | AU690768B2 (enExample) |
| CA (1) | CA2163062C (enExample) |
| FI (1) | FI955955A7 (enExample) |
| HU (1) | HU215249B (enExample) |
| IL (1) | IL116319A0 (enExample) |
| TW (1) | TW365605B (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100411856B1 (ko) * | 1995-02-03 | 2004-05-20 | 카네카 코포레이션 | α-할로케톤,α-할로히드린및에폭사이드의제조법 |
| USH1893H (en) * | 1996-07-23 | 2000-10-03 | Bristol-Myers Squibb Company | Enzymatic reduction method for the preparation of halohydrins |
| CA2319088A1 (en) * | 1998-01-28 | 1999-08-05 | Nippon Kayaku Kabushiki Kaisha | Process for producing optically active threo-3-amino-1,2-epoxy compounds |
| DE60005304T2 (de) * | 1999-01-21 | 2004-06-24 | Kaneka Corp. | Methode zur reinigung und abtrennung von (2s,3s)- oder (2r,3s)-halohydrinderivaten |
| CA2361475A1 (en) * | 1999-01-28 | 2000-08-03 | Ajinomoto Co., Inc. | Process for the preparation of .alpha.-aminoketones |
| EP1661893A3 (en) * | 1999-01-29 | 2006-06-07 | Kaneka Corporation | Process for the preparation of threo-1,2-epoxy-3-amino-4-phenylbutane derivatives |
| US6605732B1 (en) * | 1999-05-03 | 2003-08-12 | Aerojet Fine Chemicals Llc | Clean, high-yield preparation of S,S and R,S amino acid isosteres |
| KR100339831B1 (ko) * | 1999-08-18 | 2002-06-07 | 김태성 | 신규의 에틸 아지리딘 유도체 및 그 제조방법 |
| KR100708221B1 (ko) * | 1999-08-31 | 2007-04-17 | 아지노모토 가부시키가이샤 | 에폭사이드 결정의 제조방법 |
| US6992081B2 (en) | 2000-03-23 | 2006-01-31 | Elan Pharmaceuticals, Inc. | Compounds to treat Alzheimer's disease |
| ATE343562T1 (de) | 2000-03-23 | 2006-11-15 | Elan Pharm Inc | Verbindungen und verfahren zur behandlung der alzheimerschen krankheit |
| CN1217920C (zh) * | 2000-06-30 | 2005-09-07 | 艾兰制药公司 | 治疗早老性痴呆的化合物 |
| EP1666452A2 (en) | 2000-06-30 | 2006-06-07 | Elan Pharmaceuticals, Inc. | Compounds to treat Alzheimer's disease |
| US20030096864A1 (en) * | 2000-06-30 | 2003-05-22 | Fang Lawrence Y. | Compounds to treat alzheimer's disease |
| US6846813B2 (en) | 2000-06-30 | 2005-01-25 | Pharmacia & Upjohn Company | Compounds to treat alzheimer's disease |
| PE20020276A1 (es) | 2000-06-30 | 2002-04-06 | Elan Pharm Inc | COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER |
| US7253194B2 (en) * | 2000-07-24 | 2007-08-07 | The University Of Queensland | Compounds and inhibitors of phospholipases |
| US7122696B2 (en) * | 2000-11-30 | 2006-10-17 | Ajinomoto Co., Inc. | Processes for preparation of N-protected-β-amino alcohols and N-protected-β-amino epoxides |
| KR20020046948A (ko) | 2000-12-12 | 2002-06-21 | 에가시라 구니오 | 에폭사이드 결정의 제조방법 |
| AR035960A1 (es) * | 2001-04-23 | 2004-07-28 | Elan Pharm Inc | Epoxidos sustituidos y procesos para prepararlos |
| MXPA04000140A (es) * | 2001-06-27 | 2004-06-03 | Elan Pharm Inc | Derivados de beta-hidroxiamina utiles en el tratamiento de enfermedad de alzheimer. |
| DE10143742A1 (de) | 2001-09-06 | 2003-03-27 | Consortium Elektrochem Ind | Verfahren zur Herstellung von alpha-Halogenketonen |
| GB0417824D0 (en) * | 2004-08-11 | 2004-09-15 | Phoenix Chemicals Ltd | Process for asymmetric catalytic hydrogenation |
| KR101299972B1 (ko) * | 2011-03-30 | 2013-08-26 | 순천향대학교 산학협력단 | 수소화붕소나트륨을 이용한 (3Ｓ)-3-(ｔｅｒｔ-부톡시카르보닐)아미노-1-클로로-4-페닐-(2Ｓ)-부탄올의 제조방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1290787A (enExample) * | 1970-03-12 | 1972-09-27 | ||
| GB1335317A (en) * | 1971-06-23 | 1973-10-24 | Leo Pharm Prod Ltd | Cephalosporin esters salts thereof and methods for their pre paration |
| JPS53124226A (en) * | 1977-04-07 | 1978-10-30 | Mitsubishi Gas Chem Co Inc | Preparation of polyglycidyl compounds |
| CA1340588C (en) * | 1988-06-13 | 1999-06-08 | Balraj Krishan Handa | Amino acid derivatives |
| DD295369A5 (de) * | 1988-10-06 | 1991-10-31 | Tech Hochschule C Schorlemmer | Verfahren zur herstellung von substituierten glycidylanilinen |
| ATE141265T1 (de) * | 1992-05-20 | 1996-08-15 | Searle & Co | Verfahren zur herstellung von intermediaten in der synthese von retroviralen protease inhibitoren |
| US5559256A (en) * | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
-
1994
- 1994-12-13 US US08/355,373 patent/US5481011A/en not_active Expired - Fee Related
-
1995
- 1995-11-08 TW TW084111850A patent/TW365605B/zh active
- 1995-11-16 CA CA002163062A patent/CA2163062C/en not_active Expired - Fee Related
- 1995-12-10 IL IL11631995A patent/IL116319A0/xx unknown
- 1995-12-11 KR KR1019950048318A patent/KR960022492A/ko not_active Withdrawn
- 1995-12-12 HU HU9503544A patent/HU215249B/hu not_active IP Right Cessation
- 1995-12-12 CN CN95121316A patent/CN1132203A/zh active Pending
- 1995-12-12 FI FI955955A patent/FI955955A7/fi unknown
- 1995-12-12 AU AU40360/95A patent/AU690768B2/en not_active Ceased
- 1995-12-12 EP EP95309025A patent/EP0719769A2/en not_active Ceased
- 1995-12-13 JP JP7324201A patent/JPH08225557A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU4036095A (en) | 1996-06-20 |
| FI955955A0 (fi) | 1995-12-12 |
| HUT73644A (en) | 1996-09-30 |
| FI955955L (fi) | 1996-06-14 |
| EP0719769A3 (enExample) | 1996-07-31 |
| TW365605B (en) | 1999-08-01 |
| CA2163062C (en) | 1999-02-09 |
| FI955955A7 (fi) | 1996-06-14 |
| IL116319A0 (en) | 1996-03-31 |
| HU9503544D0 (en) | 1996-02-28 |
| KR960022492A (ko) | 1996-07-18 |
| US5481011A (en) | 1996-01-02 |
| CA2163062A1 (en) | 1996-06-14 |
| EP0719769A2 (en) | 1996-07-03 |
| JPH08225557A (ja) | 1996-09-03 |
| AU690768B2 (en) | 1998-04-30 |
| CN1132203A (zh) | 1996-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HMM4 | Cancellation of final prot. due to non-payment of fee |