KR960010609A - 니트로-치환된 아릴아민류의 제조 방법 - Google Patents

니트로-치환된 아릴아민류의 제조 방법 Download PDF

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KR960010609A
KR960010609A KR1019950029614A KR19950029614A KR960010609A KR 960010609 A KR960010609 A KR 960010609A KR 1019950029614 A KR1019950029614 A KR 1019950029614A KR 19950029614 A KR19950029614 A KR 19950029614A KR 960010609 A KR960010609 A KR 960010609A
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South Korea
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alkyl
alkali
nitro
halogenated
alkoxy
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KR1019950029614A
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KR100369953B1 (ko
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요아우텔라트 만프레드
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볼프강 페트로비치·귄터 슈마허
바이엘 악티엔게젤샤프트
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Publication of KR960010609A publication Critical patent/KR960010609A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/02—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of hydrogen atoms by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C07C211/52—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)

Abstract

니트로-치환된 방향족 화합물은 단순한 염기 및 산소의 존재하에 아민으로 직접 아민화될수 있다.

Description

니트로-치환된 아릴아민류의 제조 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 극성 용매에서 염기 및 산소의 존재하에 하기 식(Ⅱ)의 니트로 방향족 화합물을 하기 식(Ⅲ)의 아민 반응시키는 것을 특징으로 하는 하기식(Ⅰ)의 화합물의 제조 방법.
    상기 식에서, Ar은 C4내지 C16이며 또한 N,O 및 S로 이루어진 군에ㅓㅅ 선택된 헤테로 원자를 1 내지 2개 함유할 수 있는 모노- 또는 폴리시클릭 방향족 라디칼이고, R1은 탄소 원자및 임의로 N,O 및 S의 군에서 선택된 최대 3개의 헤테로 원자로 구성되어 있는 5 내지 16원 모노- 또는 폴리시클릭 방향족 라디칼이고, R2는 수소, C1-C8-알킬, C2-C8-알케닐, C3-C7-시클로알킬 또는 C6-C14-아릴을 나타내며, 이들 치환체들은 할로겐, C1-C4-알킬, 아미노 및(또는)C1-C4-알콕시로 1 내지 3회 치환될 수 있고 X는 할로겐 시아노 C1-C4-알킬, 할로겐화 C1-C4-알킬, C1-C4알콕시 ,할로겐화C1-C4-알콕시,C1-C4알킬메르캅토,할로겐화C1-C4-알킬메르캅토, C1-C4- 알킬술포닐, 카르복실 또는 니트로이고, n은 0,1,2 또는 3이며, n〉1이면 치환체 X 는 다를 수 있다.
  2. 제1항에 있어서, 염기가 알칼리 히드록시드, 알칼리 아미드, 알칼리 알콕시드 및 알칼리 히드리드로부터 구성된 군으로부터 선택되는 것이 특징인 방법.
  3. 제1항에 있어서, 용매가 비양성자성 극성 유지 용매 또는 암모니아 중 어느 하나인 것을 특징으로 하는 방법.
  4. 제1항에 있어서, 반응 온도는 -35 내지 120℃의 범위내인 것을 특징인 방법.
  5. 제1항에 있어서, 니트로 방향족 화합물(Ⅱ) 1몰당 아민 (Ⅲ)0.5내지 10몰이 사용되는 것이 특징인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019950029614A 1994-09-13 1995-09-12 니트로-치환된아릴아민류의제조방법 KR100369953B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4432556A DE4432556A1 (de) 1994-09-13 1994-09-13 Verfahren zur Herstellung nitrosubstituierter Arylamine
DEP4432556.8 1994-09-13

Publications (2)

Publication Number Publication Date
KR960010609A true KR960010609A (ko) 1996-04-20
KR100369953B1 KR100369953B1 (ko) 2005-01-31

Family

ID=6528085

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KR1019950029614A KR100369953B1 (ko) 1994-09-13 1995-09-12 니트로-치환된아릴아민류의제조방법

Country Status (8)

Country Link
US (1) US5612483A (ko)
EP (1) EP0701992B1 (ko)
JP (1) JPH0881422A (ko)
KR (1) KR100369953B1 (ko)
CA (1) CA2157848A1 (ko)
DE (2) DE4432556A1 (ko)
ES (1) ES2139801T3 (ko)
TW (1) TW323269B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6686499B1 (en) 1999-04-21 2004-02-03 Warner-Lambert Company Method for making 2-(N-phenylamino)benzoic acids
US7183439B2 (en) 2002-12-10 2007-02-27 Flexsys America L.P. Process for preparing 4-aminodiphenylamine intermediates
CN111732516B (zh) * 2020-07-31 2021-01-05 南昌大学 一种n-芳基取代杂环化合物的制备方法
CN118439966B (zh) * 2024-07-05 2024-10-11 南昌大学 一种对硝基苯胺类化合物的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5117063A (en) * 1991-06-21 1992-05-26 Monsanto Company Method of preparing 4-aminodiphenylamine
EP0566783A1 (en) * 1992-04-21 1993-10-27 Akzo N.V. Process for the production of nitrodiarylamines
US5252737A (en) * 1992-05-22 1993-10-12 Monsanto Company Process for preparing N-aliphatic substituted p-phenylenediamines
US5331099A (en) * 1992-05-22 1994-07-19 Monsanto Company Process for preparing p-nitroaromatic amides and products thereof

Also Published As

Publication number Publication date
TW323269B (ko) 1997-12-21
DE4432556A1 (de) 1996-03-14
US5612483A (en) 1997-03-18
EP0701992B1 (de) 1999-11-17
DE59507240D1 (de) 1999-12-23
KR100369953B1 (ko) 2005-01-31
CA2157848A1 (en) 1996-03-14
ES2139801T3 (es) 2000-02-16
EP0701992A1 (de) 1996-03-20
JPH0881422A (ja) 1996-03-26

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