KR920703597A - 항종양성 물질 be-13793c - Google Patents
항종양성 물질 be-13793cInfo
- Publication number
- KR920703597A KR920703597A KR1019920700375A KR920700375A KR920703597A KR 920703597 A KR920703597 A KR 920703597A KR 1019920700375 A KR1019920700375 A KR 1019920700375A KR 920700375 A KR920700375 A KR 920700375A KR 920703597 A KR920703597 A KR 920703597A
- Authority
- KR
- South Korea
- Prior art keywords
- substance
- acceptable salt
- tumor
- streptomyces
- mutant
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/625—Streptoverticillium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/908—Streptovirticillium
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
- Materials For Medical Uses (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
내용 없음
Description
항종양성 물질 BE-13793C
[도면의 간단한 설명]
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (6)
- 하기 구조식의 항종양성 물질 BE-13793C 또는 이의 약제학적으로 허용되는 염.
- 활성 성분으로서, 하기구조식의 항종양성 물질 BE-13793C 또는 이의 약제학적으로 허용되는 염을 유효량 포함하는 항종양제.
- 하기 구조식의 항종양성 물질 BE-13793C를 제공할 수 있는 미생물 또는 이의 돌연변이체를 배양하고, 이렇게 하여 모아진 항종양성 물질 BE-13793C를 회수함을 특징으로 하여, 항종양성 물질 BE-13793C 또는 이의 약제학적으로 허용되는 염을 제조하는 방법.
- 제3항에 있어서,스트렙토베르티실리움종 (Streptoverticilliumsp.) BA - 13793 균주 또는 이의 돌연변이체를 배양하는 방법.
- 항종양성 물질 BE-13793C를 제공하며스트렙토베르티실리움(Streptoverticillium)속 또는 이의 돌연변이체에 속하는 미생물.
- 제5항에 있어서,스트렙토베르티실리움종 BA - 13793 균주 또는 이의 돌연변이체인 미생물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7114989 | 1989-03-23 | ||
PCT/JP1990/000812 WO1991019716A1 (en) | 1989-03-23 | 1990-06-20 | Antitumor substance be-13793c |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019980703857A Division KR0177585B1 (ko) | 1998-05-23 | 1990-06-20 | 항종양성 물질 b e-13793c-생성 균주 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR920703597A true KR920703597A (ko) | 1992-12-18 |
KR0163202B1 KR0163202B1 (ko) | 1998-12-01 |
Family
ID=13452261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019920700375A KR0163202B1 (ko) | 1989-03-23 | 1990-06-20 | 항종양성 물질 be-13793c |
Country Status (13)
Country | Link |
---|---|
US (2) | US5106864A (ko) |
EP (1) | EP0388956B1 (ko) |
JP (1) | JP3010675B2 (ko) |
KR (1) | KR0163202B1 (ko) |
AT (1) | ATE110727T1 (ko) |
AU (1) | AU634247B2 (ko) |
CA (1) | CA2012955C (ko) |
DE (1) | DE69011913T2 (ko) |
DK (1) | DK0388956T3 (ko) |
ES (1) | ES2063186T3 (ko) |
HU (1) | HU210868A9 (ko) |
NO (1) | NO300812B1 (ko) |
WO (1) | WO1991019716A1 (ko) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0528030B1 (en) * | 1990-05-11 | 1997-09-17 | Banyu Pharmaceutical Co., Ltd. | Antitumor be-13793c derivative |
US5478813A (en) * | 1990-05-11 | 1995-12-26 | Banyu Pharmaceutical Co., Ltd. | Antitumor substance BE-13793C derivatives |
US5591842A (en) * | 1991-11-29 | 1997-01-07 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
US5589365A (en) * | 1991-11-29 | 1996-12-31 | Banyu Pharmaceutical Co., Ltd. | Process for producing glycosylated indolopyrrolocarbazole derivatives by culturing certain microorganisms |
US5668271A (en) * | 1991-11-29 | 1997-09-16 | Banyu Pharmaceutical Co., Ltd. | Indolopyrrolocarbazole derivatives |
EP0630242B1 (en) * | 1992-03-20 | 1999-01-20 | The Wellcome Foundation Limited | Further indole derivatives with antiviral activity |
DE4217964A1 (de) * | 1992-05-30 | 1993-12-02 | Goedecke Ag | Indolocarbazol-Imide und deren Verwendung |
DE4243321A1 (de) * | 1992-12-21 | 1994-06-23 | Goedecke Ag | Aminosäurederivate von Heterocyclen als PKC-Inhibitoren |
US5922860A (en) * | 1994-05-09 | 1999-07-13 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
US5804564A (en) * | 1994-05-09 | 1998-09-08 | Banyu Pharmaceutical Co., Ltd. | Antitumor indolopyrrolocarbazole derivatives |
WO1995034663A1 (fr) * | 1994-06-13 | 1995-12-21 | Banyu Pharmaceutical Co., Ltd. | Gene codant la glycosyl-transferase et utilisation de ce gene |
US5808060A (en) * | 1995-12-11 | 1998-09-15 | Cephalon, Inc. | Fused isoindolones |
WO1997029205A1 (en) * | 1996-02-07 | 1997-08-14 | Banyu Pharmaceutical Co., Ltd. | Effective production method of be-13793c |
GB9811624D0 (en) * | 1998-05-29 | 1998-07-29 | Merck Sharp & Dohme | Therapeutic use |
WO2004083228A1 (ja) | 1999-09-10 | 2004-09-30 | Katsuhisa Kojiri | インドロピロロカルバゾール誘導体及び抗腫瘍剤 |
FR2845996A1 (fr) * | 2002-10-16 | 2004-04-23 | Servier Lab | Nouveaux derives de[3,4-a:3,4-c]carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
DE102006038635B4 (de) * | 2006-08-19 | 2010-04-15 | Josip Marinic | Magnettonabnehmer für ein Saiteninstrument |
JP7019601B2 (ja) | 2016-07-12 | 2022-02-15 | カリフォルニア インスティチュート オブ テクノロジー | 高密度細胞増殖と代謝産物交換のための基材 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0826037B2 (ja) * | 1987-01-22 | 1996-03-13 | 協和醗酵工業株式会社 | 生理活性物質k−252の誘導体 |
DE3803620A1 (de) * | 1988-02-06 | 1989-08-17 | Goedecke Ag | Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel |
-
1990
- 1990-03-20 JP JP2071543A patent/JP3010675B2/ja not_active Expired - Fee Related
- 1990-03-21 US US07/496,701 patent/US5106864A/en not_active Expired - Lifetime
- 1990-03-22 ES ES90105439T patent/ES2063186T3/es not_active Expired - Lifetime
- 1990-03-22 DE DE69011913T patent/DE69011913T2/de not_active Expired - Fee Related
- 1990-03-22 DK DK90105439.5T patent/DK0388956T3/da active
- 1990-03-22 AT AT90105439T patent/ATE110727T1/de not_active IP Right Cessation
- 1990-03-22 EP EP90105439A patent/EP0388956B1/en not_active Expired - Lifetime
- 1990-03-23 CA CA002012955A patent/CA2012955C/en not_active Expired - Fee Related
- 1990-06-20 KR KR1019920700375A patent/KR0163202B1/ko not_active IP Right Cessation
- 1990-06-20 AU AU58351/90A patent/AU634247B2/en not_active Ceased
- 1990-06-20 WO PCT/JP1990/000812 patent/WO1991019716A1/ja active Application Filing
-
1992
- 1992-02-17 NO NO920614A patent/NO300812B1/no unknown
- 1992-12-04 US US07/985,955 patent/US5290698A/en not_active Expired - Lifetime
-
1995
- 1995-05-23 HU HU95P/P00138P patent/HU210868A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
NO920614L (no) | 1992-03-24 |
CA2012955A1 (en) | 1990-09-23 |
WO1991019716A1 (en) | 1991-12-26 |
EP0388956A3 (en) | 1991-10-02 |
EP0388956B1 (en) | 1994-08-31 |
NO300812B1 (no) | 1997-07-28 |
HU210868A9 (en) | 1995-08-28 |
ATE110727T1 (de) | 1994-09-15 |
DE69011913D1 (de) | 1994-10-06 |
NO920614D0 (no) | 1992-02-17 |
ES2063186T3 (es) | 1995-01-01 |
AU634247B2 (en) | 1993-02-18 |
DE69011913T2 (de) | 1995-02-09 |
JPH0320277A (ja) | 1991-01-29 |
CA2012955C (en) | 2001-08-21 |
JP3010675B2 (ja) | 2000-02-21 |
DK0388956T3 (da) | 1994-11-14 |
US5290698A (en) | 1994-03-01 |
US5106864A (en) | 1992-04-21 |
AU5835190A (en) | 1992-01-07 |
EP0388956A2 (en) | 1990-09-26 |
KR0163202B1 (ko) | 1998-12-01 |
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Payment date: 20060824 Year of fee payment: 9 |
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