NO920614L - Forbindelse med antitumorvirkning og fremstilling derav - Google Patents

Forbindelse med antitumorvirkning og fremstilling derav

Info

Publication number
NO920614L
NO920614L NO92920614A NO920614A NO920614L NO 920614 L NO920614 L NO 920614L NO 92920614 A NO92920614 A NO 92920614A NO 920614 A NO920614 A NO 920614A NO 920614 L NO920614 L NO 920614L
Authority
NO
Norway
Prior art keywords
antitum
relationship
preparation
effects
novel
Prior art date
Application number
NO92920614A
Other languages
English (en)
Other versions
NO300812B1 (no
NO920614D0 (no
Inventor
Katsuhisa Kojiri
Hiroyuki Suda
Akira Okura
Kenji Kawamura
Masanori Okanishi
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of NO920614D0 publication Critical patent/NO920614D0/no
Publication of NO920614L publication Critical patent/NO920614L/no
Priority to SE9301384A priority Critical patent/SE507907C2/sv
Publication of NO300812B1 publication Critical patent/NO300812B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/182Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/625Streptoverticillium
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/908Streptovirticillium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO920614A 1989-03-23 1992-02-17 Fremgangsmåte for fremstilling av antitumorsubstans BE-13793C, samt biologisk ren kultur istand til å frembringe denne NO300812B1 (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SE9301384A SE507907C2 (sv) 1992-02-17 1993-04-26 Anläggning för kalkning av vattendrag

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP7114989 1989-03-23
PCT/JP1990/000812 WO1991019716A1 (en) 1989-03-23 1990-06-20 Antitumor substance be-13793c

Publications (3)

Publication Number Publication Date
NO920614D0 NO920614D0 (no) 1992-02-17
NO920614L true NO920614L (no) 1992-03-24
NO300812B1 NO300812B1 (no) 1997-07-28

Family

ID=13452261

Family Applications (1)

Application Number Title Priority Date Filing Date
NO920614A NO300812B1 (no) 1989-03-23 1992-02-17 Fremgangsmåte for fremstilling av antitumorsubstans BE-13793C, samt biologisk ren kultur istand til å frembringe denne

Country Status (13)

Country Link
US (2) US5106864A (no)
EP (1) EP0388956B1 (no)
JP (1) JP3010675B2 (no)
KR (1) KR0163202B1 (no)
AT (1) ATE110727T1 (no)
AU (1) AU634247B2 (no)
CA (1) CA2012955C (no)
DE (1) DE69011913T2 (no)
DK (1) DK0388956T3 (no)
ES (1) ES2063186T3 (no)
HU (1) HU210868A9 (no)
NO (1) NO300812B1 (no)
WO (1) WO1991019716A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0528030B1 (en) * 1990-05-11 1997-09-17 Banyu Pharmaceutical Co., Ltd. Antitumor be-13793c derivative
US5478813A (en) * 1990-05-11 1995-12-26 Banyu Pharmaceutical Co., Ltd. Antitumor substance BE-13793C derivatives
US5591842A (en) * 1991-11-29 1997-01-07 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5589365A (en) * 1991-11-29 1996-12-31 Banyu Pharmaceutical Co., Ltd. Process for producing glycosylated indolopyrrolocarbazole derivatives by culturing certain microorganisms
US5668271A (en) * 1991-11-29 1997-09-16 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
EP0630242B1 (en) * 1992-03-20 1999-01-20 The Wellcome Foundation Limited Further indole derivatives with antiviral activity
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
DE4243321A1 (de) * 1992-12-21 1994-06-23 Goedecke Ag Aminosäurederivate von Heterocyclen als PKC-Inhibitoren
US5922860A (en) * 1994-05-09 1999-07-13 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
US5804564A (en) * 1994-05-09 1998-09-08 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
WO1995034663A1 (fr) * 1994-06-13 1995-12-21 Banyu Pharmaceutical Co., Ltd. Gene codant la glycosyl-transferase et utilisation de ce gene
US5808060A (en) * 1995-12-11 1998-09-15 Cephalon, Inc. Fused isoindolones
WO1997029205A1 (en) * 1996-02-07 1997-08-14 Banyu Pharmaceutical Co., Ltd. Effective production method of be-13793c
GB9811624D0 (en) * 1998-05-29 1998-07-29 Merck Sharp & Dohme Therapeutic use
WO2004083228A1 (ja) 1999-09-10 2004-09-30 Katsuhisa Kojiri インドロピロロカルバゾール誘導体及び抗腫瘍剤
FR2845996A1 (fr) * 2002-10-16 2004-04-23 Servier Lab Nouveaux derives de[3,4-a:3,4-c]carbazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE102006038635B4 (de) * 2006-08-19 2010-04-15 Josip Marinic Magnettonabnehmer für ein Saiteninstrument
JP7019601B2 (ja) 2016-07-12 2022-02-15 カリフォルニア インスティチュート オブ テクノロジー 高密度細胞増殖と代謝産物交換のための基材

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0826037B2 (ja) * 1987-01-22 1996-03-13 協和醗酵工業株式会社 生理活性物質k−252の誘導体
DE3803620A1 (de) * 1988-02-06 1989-08-17 Goedecke Ag Indolocarbazol-derivate, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
CA2012955A1 (en) 1990-09-23
WO1991019716A1 (en) 1991-12-26
EP0388956A3 (en) 1991-10-02
EP0388956B1 (en) 1994-08-31
NO300812B1 (no) 1997-07-28
HU210868A9 (en) 1995-08-28
KR920703597A (ko) 1992-12-18
ATE110727T1 (de) 1994-09-15
DE69011913D1 (de) 1994-10-06
NO920614D0 (no) 1992-02-17
ES2063186T3 (es) 1995-01-01
AU634247B2 (en) 1993-02-18
DE69011913T2 (de) 1995-02-09
JPH0320277A (ja) 1991-01-29
CA2012955C (en) 2001-08-21
JP3010675B2 (ja) 2000-02-21
DK0388956T3 (da) 1994-11-14
US5290698A (en) 1994-03-01
US5106864A (en) 1992-04-21
AU5835190A (en) 1992-01-07
EP0388956A2 (en) 1990-09-26
KR0163202B1 (ko) 1998-12-01

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