KR900006517A - 항생제 pb-6042류 - Google Patents

항생제 pb-6042류 Download PDF

Info

Publication number
KR900006517A
KR900006517A KR1019890015059A KR890015059A KR900006517A KR 900006517 A KR900006517 A KR 900006517A KR 1019890015059 A KR1019890015059 A KR 1019890015059A KR 890015059 A KR890015059 A KR 890015059A KR 900006517 A KR900006517 A KR 900006517A
Authority
KR
South Korea
Prior art keywords
compound
microorganism
enterobacter
antibiotic
enterobacter agglomerans
Prior art date
Application number
KR1019890015059A
Other languages
English (en)
Other versions
KR970005488B1 (ko
Inventor
다다시 요시다
데루오 하또리
고이찌 마쓰모또
요시히로 데루이
준이찌 쇼오지
Original Assignee
요시또시 가즈오
시오노기 세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 요시또시 가즈오, 시오노기 세이야꾸 가부시끼가이샤 filed Critical 요시또시 가즈오
Publication of KR900006517A publication Critical patent/KR900006517A/ko
Application granted granted Critical
Publication of KR970005488B1 publication Critical patent/KR970005488B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

Abstract

내용없음.

Description

항생제 PB-6042류
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 PB-6042류의 TLC 크로마토그래피를 나타낸다.
제2도는 PB-6042류의 HPLC 크로마토그래피를 나타낸다.
제3도는 PB-6042류의 IR 스펙트럼을 나타낸다.

Claims (5)

  1. 하기 일반식(Ⅰ)의 화합물 또는 그의 염.
  2. 제1항의 화합물을 생산함을 특징으로 하는 엔테로박터(Enterobacter)속에 속하는 미생물.
  3. 제2항에 있어서, 엔테로박터 아글로메란스(Enterobacter agglomerans)인 미생물.
  4. 제3항에 있어서, 엔테로박터 아글로메란스 PB-6042인 미생물.
  5. 제2, 3 또는 4항의 미생물을 적당한 배양 배치에서 배양하고, 제1항의 화합물을 단리시킴을 특징으로 하는 제1항의 화합물의 제조방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890015059A 1988-10-20 1989-10-19 항생제 pb-6042류 KR970005488B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP26657588 1988-10-20
JP266575/1988 1988-10-20

Publications (2)

Publication Number Publication Date
KR900006517A true KR900006517A (ko) 1990-05-08
KR970005488B1 KR970005488B1 (ko) 1997-04-16

Family

ID=17432717

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890015059A KR970005488B1 (ko) 1988-10-20 1989-10-19 항생제 pb-6042류

Country Status (7)

Country Link
US (1) US5045458A (ko)
EP (1) EP0365329B1 (ko)
KR (1) KR970005488B1 (ko)
AT (1) ATE73789T1 (ko)
DE (1) DE68901024D1 (ko)
ES (1) ES2052020T3 (ko)
GR (1) GR3004095T3 (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0365329B1 (en) * 1988-10-20 1992-03-18 Shionogi & Co., Ltd. Antibiotics active against anaerobic bacteria, their production and use, and strains of enterobacter producing the same
AU2267992A (en) * 1991-08-27 1993-03-16 Upjohn Company, The Compounds used for the inhibition of hiv-protease
EP0720607A1 (en) * 1993-09-17 1996-07-10 PHARMACIA & UPJOHN COMPANY Substituted tetronic acids useful for treating hiv and other retroviruses
ATE232867T1 (de) * 1995-03-20 2003-03-15 Upjohn Co Tetronsäurederivate zur behandlung von hiv- und anderen retroviruserkrankungen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60258173A (ja) * 1984-06-01 1985-12-20 Kanegafuchi Chem Ind Co Ltd ａ−〔３−タ−シヤリ−ブチル−５−（１，１−ジメチル−２−ヒドロキシエチル）−４−ヒドロキシベンジリデン〕−γ−ブチロラクトンおよびその製造法並びにそれを有効成分とする抗炎症剤および血小板凝集阻害剤
JPS6471867A (en) * 1987-09-11 1989-03-16 Taisho Pharmaceutical Co Ltd Propionic acid compound
JPH01227355A (ja) * 1988-03-11 1989-09-11 Sanyo Electric Co Ltd 非水電解液電池
DE3813806A1 (de) * 1988-04-23 1989-11-02 Basf Ag 11-hydroxy-(gamma)-dodecalacton und seine herstellung
EP0365329B1 (en) * 1988-10-20 1992-03-18 Shionogi & Co., Ltd. Antibiotics active against anaerobic bacteria, their production and use, and strains of enterobacter producing the same
JPH0396182A (ja) * 1989-09-08 1991-04-22 Citizen Watch Co Ltd 液晶テレビジョンの表示方式

Also Published As

Publication number Publication date
EP0365329A3 (en) 1990-08-29
GR3004095T3 (ko) 1993-03-31
ES2052020T3 (es) 1994-07-01
DE68901024D1 (de) 1992-04-23
KR970005488B1 (ko) 1997-04-16
ATE73789T1 (de) 1992-04-15
EP0365329B1 (en) 1992-03-18
EP0365329A2 (en) 1990-04-25
US5045458A (en) 1991-09-03

Similar Documents

Publication Publication Date Title
AU541097B2 (en) Novel derivatives of c-076 compounds
KR840007257A (ko) 레베카마이신과 그것의 제조방법
KR920703597A (ko) 항종양성 물질 be-13793c
ES8602135A1 (es) Un procedimiento para la preparacion de un antibiotico bbm-2478.
ES8604256A1 (es) Un procedimiento para la preparacion de 9-deoxo-9a-metil-9a-aza-9a-homoeritromicina d o una sal de la misma
KR840005483A (ko) A47934 항생물질의 제조방법
KR900016264A (ko) 항생제 tan-1057
KR900006517A (ko) 항생제 pb-6042류
GB1518633A (en) Glycopeptide
KR910000790A (ko) 고리형 테트라펩티드 및 그의 제조방법
KR910014398A (ko) 항생제 데옥시물룬도칸딘, 이의 제조방법 및 약제로서의 이의 용도
KR890014457A (ko) 신규 아족시 화합물 및 그의 제조방법
KR830005176A (ko) 티아졸 유도체의 제조방법
ES475179A1 (es) Un metodo mejorado para producir antibiotico c-15003 p-4.
DK158083A (da) Fremgangsmaade til fremstilling af et antibiotisk komplex, omfattende erythromycin d og estere deraf, eller dets enkelte komponenter
CA2041237A1 (en) UCF1 Compounds Derivatives Thereof and Processes for Their Preparation
KR910012257A (ko) 벤즈안트라센 화합물 및 이의 제조방법
KR840007437A (ko) 항생제 a 51568 인자 a 및 b의 제조방법
KR910003113A (ko) 항생물질 플러스박신
KR910014509A (ko) 항생성 알리사마이신, 이의 제조방법 및 용도
KR920002497A (ko) 스테롤 화합물
KR860002574A (ko) 항생물질 at 2433 복합체의 제조방법
KR830007836A (ko) Ka-6643계 항생물질의 제조방법
FI864887A (fi) Foerfarande foer framstaellning av 1-metyl-1,4-androstadien-3,17-dion.
FI841240A0 (fi) Foerbaettringar i makrolidantibiotika.

Legal Events

Date Code Title Description
A201 Request for examination
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
NORF Unpaid initial registration fee