KR920017644A - 폐 투여용 시클로스포린 형태 - Google Patents

폐 투여용 시클로스포린 형태 Download PDF

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Publication number
KR920017644A
KR920017644A KR1019920004494A KR920004494A KR920017644A KR 920017644 A KR920017644 A KR 920017644A KR 1019920004494 A KR1019920004494 A KR 1019920004494A KR 920004494 A KR920004494 A KR 920004494A KR 920017644 A KR920017644 A KR 920017644A
Authority
KR
South Korea
Prior art keywords
iii
pharmaceutical composition
cyclosporin
particles
crystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019920004494A
Other languages
English (en)
Korean (ko)
Inventor
모레이 존
롬멜트 안드레아스
리스트 마틴
Original Assignee
진 크라머·한스루돌프 하우스
산도즈 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 진 크라머·한스루돌프 하우스, 산도즈 리미티드 filed Critical 진 크라머·한스루돌프 하우스
Publication of KR920017644A publication Critical patent/KR920017644A/ko
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019920004494A 1991-03-18 1992-03-17 폐 투여용 시클로스포린 형태 Ceased KR920017644A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9105705 1991-03-18
GB919105705A GB9105705D0 (en) 1991-03-18 1991-03-18 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
KR920017644A true KR920017644A (ko) 1992-10-21

Family

ID=10691762

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019920004494A Ceased KR920017644A (ko) 1991-03-18 1992-03-17 폐 투여용 시클로스포린 형태

Country Status (29)

Country Link
US (1) US5719123A (enExample)
EP (1) EP0504760B1 (enExample)
JP (1) JP2549794B2 (enExample)
KR (1) KR920017644A (enExample)
AT (1) AT404553B (enExample)
AU (1) AU658172B2 (enExample)
CA (1) CA2063106C (enExample)
CH (1) CH685229A5 (enExample)
CZ (1) CZ281260B6 (enExample)
DE (1) DE4208258B4 (enExample)
DK (1) DK0504760T3 (enExample)
ES (1) ES2093130T3 (enExample)
FI (1) FI921125L (enExample)
FR (1) FR2674249A1 (enExample)
GB (2) GB9105705D0 (enExample)
GR (1) GR3021497T3 (enExample)
HU (1) HU208492B (enExample)
IE (1) IE67627B1 (enExample)
IL (1) IL101244A (enExample)
IT (1) IT1255040B (enExample)
LU (1) LU88087A1 (enExample)
MX (1) MX9201141A (enExample)
NO (1) NO310754B1 (enExample)
NZ (1) NZ241975A (enExample)
RU (1) RU2098122C1 (enExample)
SA (1) SA92120536B1 (enExample)
SK (1) SK279576B6 (enExample)
TW (1) TW215901B (enExample)
ZA (1) ZA921987B (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5837677B2 (ja) * 1981-01-13 1983-08-17 松下電器産業株式会社 誘導加熱調理器
JPH07111905B2 (ja) * 1987-07-23 1995-11-29 株式会社東芝 誘導加熱調理器の負荷適否検知回路
KR100277622B1 (ko) * 1992-06-12 2001-01-15 이타가키 히로시 흡입용 초미립자 분말 및 그의 제조방법
US5512269A (en) * 1993-06-09 1996-04-30 Burroughs Wellcome, Co. Method of treating retained pulmonary secretions
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
WO1998001147A1 (en) * 1996-07-08 1998-01-15 Rhone-Poulenc Rorer Limited Medicinal cyclosporin-a aerosol solution formulation
US6517860B1 (en) 1996-12-31 2003-02-11 Quadrant Holdings Cambridge, Ltd. Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery
US5898028A (en) * 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
TW581681B (en) * 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US20020006901A1 (en) * 1999-02-05 2002-01-17 Aldo T. Iacono Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease
FI20002217A7 (fi) * 1999-12-30 2001-07-01 Orion Yhtymae Oyj Inhalaatiopartikkelit
FI20010115A0 (fi) * 2001-01-18 2001-01-18 Orion Corp Menetelmä nanopartikkelien valmistamiseksi
RU2203064C2 (ru) * 2001-03-11 2003-04-27 Каменев Виктор Федорович Способ лечения аспириновой бронхиальной астмы
PT1435910E (pt) * 2001-10-19 2009-09-07 Isotechnika Inc Novos pré-concentrados de microemulsão de análogos da ciclosporina
WO2004069223A2 (en) * 2003-02-06 2004-08-19 Cipla Ltd Pharmaceutical compositions comprising immunosuppressants and uses thereof
CA2516733C (en) * 2003-02-21 2011-09-27 The University Of Bath Process for the production of particles
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US20060078622A1 (en) * 2004-08-13 2006-04-13 Emisphere Technologies, Inc. Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US7151085B2 (en) 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
US20080114577A1 (en) * 2005-11-30 2008-05-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational methods and systems associated with nutraceutical related assays
US20070124218A1 (en) * 2005-11-30 2007-05-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized nutraceutical selection and packaging
US8340944B2 (en) * 2005-11-30 2012-12-25 The Invention Science Fund I, Llc Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US20070174128A1 (en) * 2005-11-30 2007-07-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging
US20080052114A1 (en) * 2005-11-30 2008-02-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems and methods related to nutraceuticals
US7927787B2 (en) * 2006-06-28 2011-04-19 The Invention Science Fund I, Llc Methods and systems for analysis of nutraceutical associated components
US20070289258A1 (en) * 2006-06-14 2007-12-20 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Individualized pharmaceutical selection and packaging
US20070124176A1 (en) * 2005-11-30 2007-05-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US8297028B2 (en) 2006-06-14 2012-10-30 The Invention Science Fund I, Llc Individualized pharmaceutical selection and packaging
US7974856B2 (en) 2005-11-30 2011-07-05 The Invention Science Fund I, Llc Computational systems and methods related to nutraceuticals
US8000981B2 (en) 2005-11-30 2011-08-16 The Invention Science Fund I, Llc Methods and systems related to receiving nutraceutical associated information
US20070136092A1 (en) * 2005-11-30 2007-06-14 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging
US7827042B2 (en) * 2005-11-30 2010-11-02 The Invention Science Fund I, Inc Methods and systems related to transmission of nutraceutical associated information
US20080004905A1 (en) * 2006-06-28 2008-01-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for analysis of nutraceutical associated components
US20110145009A1 (en) * 2005-11-30 2011-06-16 Jung Edward K Y Methods and systems related to transmission of nutraceutical associatd information
US20080033763A1 (en) * 2005-11-30 2008-02-07 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems related to receiving nutraceutical associated information
US10296720B2 (en) * 2005-11-30 2019-05-21 Gearbox Llc Computational systems and methods related to nutraceuticals
US20080103746A1 (en) * 2005-11-30 2008-05-01 Searete Llc, A Limited Liability Corporation Systems and methods for pathogen detection and response
DE102006051512A1 (de) 2005-12-06 2007-06-14 Pari GmbH Spezialisten für effektive Inhalation Pharmazeutische Medikamentenzusammensetzungen mit Cyclosporin
US20070219127A1 (en) * 2006-03-20 2007-09-20 Walt John G Cyclosporin a compositions
MX362271B (es) * 2011-05-27 2019-01-10 Allergan Inc Nueva forma cristalina de ciclosporina a, metodos de preparacion y metodos para su uso.
JO3410B1 (ar) 2011-06-07 2019-10-20 Otsuka Pharma Co Ltd تركيبة أريبيبرازول مجفف بالتبريد
ES2666191T3 (es) * 2011-11-15 2018-05-03 Allergan, Inc. Un proceso para la cristalización de la forma 2 de la ciclosporina A

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203564B (en) * 1987-12-21 1991-08-28 Sandoz Ag Process for producing new orthorombos cyclosporin without solvatation
CH679119A5 (enExample) * 1988-05-13 1991-12-31 Sandoz Ag
GB8916901D0 (en) * 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
ATA53492A (de) 1998-05-15
JPH0585940A (ja) 1993-04-06
NO921012D0 (no) 1992-03-16
SK279576B6 (sk) 1999-01-11
ZA921987B (en) 1993-09-20
IE920839A1 (en) 1992-09-23
AU1294092A (en) 1992-09-24
AT404553B (de) 1998-12-28
GB2253853A (en) 1992-09-23
CA2063106A1 (en) 1992-09-19
CA2063106C (en) 2002-12-17
ITRM920181A1 (it) 1993-09-17
FR2674249B1 (enExample) 1995-05-12
GB9105705D0 (en) 1991-05-01
HU208492B (en) 1993-11-29
IT1255040B (it) 1995-10-13
DK0504760T3 (da) 1996-12-23
LU88087A1 (fr) 1993-10-27
HU9200735D0 (en) 1992-05-28
HUT61324A (en) 1992-12-28
AU658172B2 (en) 1995-04-06
GB9205554D0 (en) 1992-04-29
ITRM920181A0 (it) 1992-03-17
CZ281260B6 (cs) 1996-07-17
CS78592A3 (en) 1992-10-14
RU2098122C1 (ru) 1997-12-10
NZ241975A (en) 1994-04-27
US5719123A (en) 1998-02-17
GB2253853B (en) 1995-04-26
TW215901B (enExample) 1993-11-11
IL101244A0 (en) 1992-11-15
SA92120536B1 (ar) 2005-04-27
EP0504760B1 (en) 1996-10-09
JP2549794B2 (ja) 1996-10-30
DE4208258A1 (de) 1992-09-24
FI921125A7 (fi) 1992-09-19
EP0504760A1 (en) 1992-09-23
IL101244A (en) 1996-10-31
NO921012L (no) 1992-09-21
NO310754B1 (no) 2001-08-27
FI921125L (fi) 1992-09-19
FR2674249A1 (fr) 1992-09-25
FI921125A0 (fi) 1992-03-16
DE4208258B4 (de) 2007-07-12
IE67627B1 (en) 1996-04-17
CH685229A5 (de) 1995-05-15
GR3021497T3 (en) 1997-01-31
ES2093130T3 (es) 1996-12-16
MX9201141A (es) 1992-10-01

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