ITRM920181A1 - Forma di ciclosporina adatta alla somministrazione per via polmonare e procedimento di preparazione. - Google Patents

Forma di ciclosporina adatta alla somministrazione per via polmonare e procedimento di preparazione.

Info

Publication number
ITRM920181A1
ITRM920181A1 IT000181A ITRM920181A ITRM920181A1 IT RM920181 A1 ITRM920181 A1 IT RM920181A1 IT 000181 A IT000181 A IT 000181A IT RM920181 A ITRM920181 A IT RM920181A IT RM920181 A1 ITRM920181 A1 IT RM920181A1
Authority
IT
Italy
Prior art keywords
cyclosporine
preparation procedure
pulmonary administration
pulmonary
administration
Prior art date
Application number
IT000181A
Other languages
English (en)
Inventor
Martin List
John Morley
Andreas Rummelt
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ITRM920181A0 publication Critical patent/ITRM920181A0/it
Publication of ITRM920181A1 publication Critical patent/ITRM920181A1/it
Application granted granted Critical
Publication of IT1255040B publication Critical patent/IT1255040B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ITRM920181A 1991-03-18 1992-03-17 Forma di ciclosporina adatta alla somministrazione per via polmonare eprocedimento di preparazione. IT1255040B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919105705A GB9105705D0 (en) 1991-03-18 1991-03-18 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
ITRM920181A0 ITRM920181A0 (it) 1992-03-17
ITRM920181A1 true ITRM920181A1 (it) 1993-09-17
IT1255040B IT1255040B (it) 1995-10-13

Family

ID=10691762

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920181A IT1255040B (it) 1991-03-18 1992-03-17 Forma di ciclosporina adatta alla somministrazione per via polmonare eprocedimento di preparazione.

Country Status (29)

Country Link
US (1) US5719123A (it)
EP (1) EP0504760B1 (it)
JP (1) JP2549794B2 (it)
KR (1) KR920017644A (it)
AT (1) AT404553B (it)
AU (1) AU658172B2 (it)
CA (1) CA2063106C (it)
CH (1) CH685229A5 (it)
CZ (1) CZ281260B6 (it)
DE (1) DE4208258B4 (it)
DK (1) DK0504760T3 (it)
ES (1) ES2093130T3 (it)
FI (1) FI921125A (it)
FR (1) FR2674249A1 (it)
GB (2) GB9105705D0 (it)
GR (1) GR3021497T3 (it)
HU (1) HU208492B (it)
IE (1) IE67627B1 (it)
IL (1) IL101244A (it)
IT (1) IT1255040B (it)
LU (1) LU88087A1 (it)
MX (1) MX9201141A (it)
NO (1) NO310754B1 (it)
NZ (1) NZ241975A (it)
RU (1) RU2098122C1 (it)
SA (1) SA92120536B1 (it)
SK (1) SK279576B6 (it)
TW (1) TW215901B (it)
ZA (1) ZA921987B (it)

Families Citing this family (42)

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JPS5837677B2 (ja) * 1981-01-13 1983-08-17 松下電器産業株式会社 誘導加熱調理器
JPH07111905B2 (ja) * 1987-07-23 1995-11-29 株式会社東芝 誘導加熱調理器の負荷適否検知回路
ES2177544T3 (es) * 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
US5512269A (en) * 1993-06-09 1996-04-30 Burroughs Wellcome, Co. Method of treating retained pulmonary secretions
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
JP2000514085A (ja) * 1996-07-08 2000-10-24 ローヌ―プーラン・ロウラー・リミテッド 医薬シクロスポリンａエーロゾル溶液処方物
ZA9711732B (en) 1996-12-31 1998-12-28 Quadrant Holdings Cambridge Methods and compositions for improvement bioavailability of bioactive agents for mucosal delivery
US5898028A (en) * 1997-03-20 1999-04-27 Novo Nordisk A/S Method for producing powder formulation comprising an insulin
TW581681B (en) 1998-02-20 2004-04-01 Nektar Therapeutics Liquid crystal forms of cyclosporin
US20020006901A1 (en) * 1999-02-05 2002-01-17 Aldo T. Iacono Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease
FI20002217A (fi) * 1999-12-30 2001-07-01 Orion Yhtymae Oyj Inhalaatiopartikkelit
FI20010115A0 (fi) * 2001-01-18 2001-01-18 Orion Corp Menetelmä nanopartikkelien valmistamiseksi
EP1435910B9 (en) * 2001-10-19 2010-02-03 Isotechnika Inc. Novel cyclosporin analog microemulsion preconcentrates
WO2004069223A2 (en) * 2003-02-06 2004-08-19 Cipla Ltd Pharmaceutical compositions comprising immunosuppressants and uses thereof
ES2520841T3 (es) * 2003-02-21 2014-11-11 University Of Bath Procedimiento para la producción de partículas
US20050059583A1 (en) * 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US20060078623A1 (en) * 2004-08-13 2006-04-13 Emisphere Technologies, Inc. Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
US7135455B2 (en) * 2004-11-15 2006-11-14 Allergan, Inc Methods for the therapeutic use of cyclosporine components
US7151085B2 (en) 2004-11-15 2006-12-19 Allergan, Inc. Therapeutic methods using cyclosporine components
US20080033763A1 (en) * 2005-11-30 2008-02-07 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems related to receiving nutraceutical associated information
US7974856B2 (en) 2005-11-30 2011-07-05 The Invention Science Fund I, Llc Computational systems and methods related to nutraceuticals
US8297028B2 (en) 2006-06-14 2012-10-30 The Invention Science Fund I, Llc Individualized pharmaceutical selection and packaging
US20070124176A1 (en) * 2005-11-30 2007-05-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US7927787B2 (en) * 2006-06-28 2011-04-19 The Invention Science Fund I, Llc Methods and systems for analysis of nutraceutical associated components
US20080052114A1 (en) * 2005-11-30 2008-02-28 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems and methods related to nutraceuticals
US10296720B2 (en) * 2005-11-30 2019-05-21 Gearbox Llc Computational systems and methods related to nutraceuticals
US8340944B2 (en) * 2005-11-30 2012-12-25 The Invention Science Fund I, Llc Computational and/or control systems and methods related to nutraceutical agent selection and dosing
US20080004905A1 (en) * 2006-06-28 2008-01-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Methods and systems for analysis of nutraceutical associated components
US8068991B2 (en) * 2005-11-30 2011-11-29 The Invention Science Fund I, Llc Systems and methods for transmitting pathogen related information and responding
US20070289258A1 (en) * 2006-06-14 2007-12-20 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Individualized pharmaceutical selection and packaging
US8000981B2 (en) 2005-11-30 2011-08-16 The Invention Science Fund I, Llc Methods and systems related to receiving nutraceutical associated information
US7827042B2 (en) * 2005-11-30 2010-11-02 The Invention Science Fund I, Inc Methods and systems related to transmission of nutraceutical associated information
US20110145009A1 (en) * 2005-11-30 2011-06-16 Jung Edward K Y Methods and systems related to transmission of nutraceutical associatd information
US20080114577A1 (en) * 2005-11-30 2008-05-15 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational methods and systems associated with nutraceutical related assays
US20070136092A1 (en) * 2005-11-30 2007-06-14 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging
US20070124218A1 (en) * 2005-11-30 2007-05-31 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized nutraceutical selection and packaging
US20070174128A1 (en) * 2005-11-30 2007-07-26 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational and/or control systems related to individualized pharmaceutical and nutraceutical selection and packaging
DE102006051512A1 (de) 2005-12-06 2007-06-14 Pari GmbH Spezialisten für effektive Inhalation Pharmazeutische Medikamentenzusammensetzungen mit Cyclosporin
US20070219127A1 (en) * 2006-03-20 2007-09-20 Walt John G Cyclosporin a compositions
BR112013030554B1 (pt) * 2011-05-27 2020-12-15 Allergan, Inc. Forma cristalina de ciclosporina a, métodos de preparação e métodos para uso da mesma
JO3410B1 (ar) 2011-06-07 2019-10-20 Otsuka Pharma Co Ltd تركيبة أريبيبرازول مجفف بالتبريد
KR102072252B1 (ko) * 2011-11-15 2020-01-31 알러간, 인코포레이티드 사이클로스포린 a 제2형 및 그의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU203564B (en) * 1987-12-21 1991-08-28 Sandoz Ag Process for producing new orthorombos cyclosporin without solvatation
CH679119A5 (it) * 1988-05-13 1991-12-31 Sandoz Ag
GB8916901D0 (en) * 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
KR920017644A (ko) 1992-10-21
HUT61324A (en) 1992-12-28
NZ241975A (en) 1994-04-27
GB9105705D0 (en) 1991-05-01
CS78592A3 (en) 1992-10-14
MX9201141A (es) 1992-10-01
CA2063106A1 (en) 1992-09-19
DE4208258B4 (de) 2007-07-12
FI921125A (fi) 1992-09-19
AU658172B2 (en) 1995-04-06
IL101244A0 (en) 1992-11-15
TW215901B (it) 1993-11-11
GB2253853B (en) 1995-04-26
GR3021497T3 (en) 1997-01-31
NO921012L (no) 1992-09-21
NO921012D0 (no) 1992-03-16
RU2098122C1 (ru) 1997-12-10
CA2063106C (en) 2002-12-17
IE67627B1 (en) 1996-04-17
CZ281260B6 (cs) 1996-07-17
EP0504760B1 (en) 1996-10-09
LU88087A1 (fr) 1993-10-27
AT404553B (de) 1998-12-28
IE920839A1 (en) 1992-09-23
FR2674249B1 (it) 1995-05-12
IT1255040B (it) 1995-10-13
IL101244A (en) 1996-10-31
FI921125A0 (fi) 1992-03-16
NO310754B1 (no) 2001-08-27
DK0504760T3 (da) 1996-12-23
GB2253853A (en) 1992-09-23
HU9200735D0 (en) 1992-05-28
JPH0585940A (ja) 1993-04-06
GB9205554D0 (en) 1992-04-29
AU1294092A (en) 1992-09-24
FR2674249A1 (fr) 1992-09-25
ITRM920181A0 (it) 1992-03-17
ATA53492A (de) 1998-05-15
JP2549794B2 (ja) 1996-10-30
US5719123A (en) 1998-02-17
DE4208258A1 (de) 1992-09-24
HU208492B (en) 1993-11-29
EP0504760A1 (en) 1992-09-23
SK279576B6 (sk) 1999-01-11
ZA921987B (en) 1993-09-20
CH685229A5 (de) 1995-05-15
SA92120536B1 (ar) 2005-04-27
ES2093130T3 (es) 1996-12-16

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970324