KR920007621A - 배분 패키지내에 있는 겔 형태의 약제학적 조성물 - Google Patents

배분 패키지내에 있는 겔 형태의 약제학적 조성물 Download PDF

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Publication number
KR920007621A
KR920007621A KR1019910017216A KR910017216A KR920007621A KR 920007621 A KR920007621 A KR 920007621A KR 1019910017216 A KR1019910017216 A KR 1019910017216A KR 910017216 A KR910017216 A KR 910017216A KR 920007621 A KR920007621 A KR 920007621A
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South Korea
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agent
composition
active ingredient
gel
pharmaceutical composition
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KR1019910017216A
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KR100213513B1 (ko
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삐에르 따송
비뜨리스 바그뇌
장-루이스 비르
Original Assignee
앙드르제이 레드지옹
소시에떼 데 프로듀이 네슬레 소시에떼 아노님
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Physiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

내용 없음

Description

배분 패키지내에 있는 겔 형태의 약제학적 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 배분 동안에 흘러내리지 않고 감각적으로 수용될 수있는 모조 플라스틱 수 - 분산성 겔에 유효 성분이 균일하게 배분되어 지고, 20 내지 150ml의 내부 용적을 갖고 용적이 5ml를 초과하지 않는 측정 칸막이 및 치료량당 1회 또는 2회의 압박으로 치료량을 배분할 수 있도록 설계된 측정 펌프가 내장되어진 배분기 팩내에 겔이 함유되어 있으며, 배분기의 용량이 적어도 5일의 치료를 위해서는 충분한 용량임을 특징으로 하는, 유효성분의 용액을 경구 투여 겔 시럽으로서 일반적으로 나타낸 패키지 내의 약제학적 조성물.
  2. 제1항에 있어서, 겔이 크산탄검 또는 텍스트란, 셀룰로스 및 이들 유도체, 녹말 및 텍스트린, 카르보머, 아크릴아미드, 아크릴아미딘, 폴리글리콜 및 지방산과의 폴리올의 에스테르로 부터 선택된 겔화제 0.2 내지 5%를 함유하는 조성물.
  3. 제2항에 있어서, 겔화제가 딕소트로프제로서 셀룰로스 유도체 및 마그네슘 알루미노실리케이트로 구성된 혼합물인 조성물.
  4. 제2항에 있어서,겔이 겔화제로서 크산탄검을 함유하는 조성물.
  5. 제1항에 있어서, 유효성분이 개방이거나 밀폐 매트릭스 또는 소포시스템내에서 캡슐화되어 조성물의 감각수용 특성을 개선시킨 조성물.
  6. 제1항에 있어서, 유효성분이 오일-물 형태의 액/액 에멀션 또는 고/액 서스팬션내 분산되어진 조성물.
  7. 제1항에 있어서, 설탕, 감미제, 방부제, 색소 및 향미제를 함유하는 조성물.
  8. 제1항에 있어서, 유효성분이 제산제, 제사제, 향히스타민제, 제토제, 진해제, 항염증제, 진통제/해열제, 기관지 점막 조절제, 진경제, 호흡 자양제/항천식제,전신계 α-교감신경흥분제,완화제,비타민 복합체, 또는 이들 유효 성분들의 혼화성 배합물인 조성물.
  9. 유효성분을 수성매질에 용해시키거나 분산시키고, 용액 또는 분산액을 감미제, 방부제 및 향미제와 혼합시킨다음, 얻어진 혼합물에 교반하면서 겔화제를 첨가한 후, 형성된 겔시럽을 측정칸막이 및 측정 펌프가 내장된 배분기 팩에 채원 넣는것을 특징으로 하는 팩으로 된 약제학적 조성물의 제조방법.
  10. 제9항에 있어서, 유효성분을 수성매질에 용해시키거나 분산시키기 전에, 유효성분을 캡슐화하여 조성물의 감각수용 특성을 개선시키는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910017216A 1990-10-04 1991-10-01 배분 패키지내에 있는 겔 형태의 약제학적 조성물 KR100213513B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP90118920 1990-10-04
EP90118920.9 1990-10-04

Publications (2)

Publication Number Publication Date
KR920007621A true KR920007621A (ko) 1992-05-27
KR100213513B1 KR100213513B1 (ko) 1999-08-02

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KR1019910017216A KR100213513B1 (ko) 1990-10-04 1991-10-01 배분 패키지내에 있는 겔 형태의 약제학적 조성물

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US (2) US5300302A (ko)
EP (1) EP0479005B1 (ko)
JP (1) JP3219799B2 (ko)
KR (1) KR100213513B1 (ko)
AT (1) ATE131039T1 (ko)
AU (1) AU643067B2 (ko)
BR (1) BR9104280A (ko)
CA (1) CA2052615C (ko)
DE (1) DE69115210T2 (ko)
DK (1) DK0479005T3 (ko)
DZ (1) DZ1530A1 (ko)
EG (1) EG19906A (ko)
ES (1) ES2081407T3 (ko)
FI (1) FI104947B (ko)
GR (1) GR3018893T3 (ko)
HU (1) HU219222B (ko)
IE (1) IE72146B1 (ko)
IL (1) IL99509A (ko)
MA (1) MA22289A1 (ko)
MX (1) MX9101391A (ko)
MY (1) MY107488A (ko)
NO (1) NO303525B1 (ko)
NZ (1) NZ240068A (ko)
PT (1) PT99143B (ko)
RU (1) RU2093143C1 (ko)
TN (1) TNSN91085A1 (ko)
ZA (1) ZA917627B (ko)

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IE913286A1 (en) 1992-04-08
MX9101391A (es) 1992-04-01
DZ1530A1 (fr) 2002-02-17
ZA917627B (en) 1992-06-24
HU912990D0 (en) 1992-01-28
IL99509A (en) 1995-08-31
NZ240068A (en) 1994-05-26
EP0479005B1 (fr) 1995-12-06
US5505959A (en) 1996-04-09
FI914607A0 (fi) 1991-10-01
US5300302A (en) 1994-04-05
ES2081407T3 (es) 1996-03-01
CA2052615C (en) 2001-01-16
KR100213513B1 (ko) 1999-08-02
CA2052615A1 (en) 1992-04-05
NO913847D0 (no) 1991-10-01
HUT59587A (en) 1992-06-29
RU2093143C1 (ru) 1997-10-20
DK0479005T3 (da) 1996-03-11
DE69115210D1 (de) 1996-01-18
JP3219799B2 (ja) 2001-10-15
IE72146B1 (en) 1997-03-26
AU8458991A (en) 1992-04-09
PT99143A (pt) 1993-12-31
EP0479005A1 (fr) 1992-04-08
FI104947B (fi) 2000-05-15
AU643067B2 (en) 1993-11-04
MA22289A1 (fr) 1992-04-01
JPH04247023A (ja) 1992-09-03
NO913847L (no) 1992-04-06
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EG19906A (fr) 1996-05-31
HU219222B (en) 2001-03-28
ATE131039T1 (de) 1995-12-15
MY107488A (en) 1995-12-30
GR3018893T3 (en) 1996-05-31
FI914607A (fi) 1992-04-05
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PT99143B (pt) 1999-04-30
NO303525B1 (no) 1998-07-27
BR9104280A (pt) 1992-06-02

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