KR920002296B1 - 펜옥시아세트산 유도체 및 이의 제조방법 - Google Patents

펜옥시아세트산 유도체 및 이의 제조방법 Download PDF

Info

Publication number
KR920002296B1
KR920002296B1 KR1019870011259A KR870011259A KR920002296B1 KR 920002296 B1 KR920002296 B1 KR 920002296B1 KR 1019870011259 A KR1019870011259 A KR 1019870011259A KR 870011259 A KR870011259 A KR 870011259A KR 920002296 B1 KR920002296 B1 KR 920002296B1
Authority
KR
South Korea
Prior art keywords
group
compound
pyrazolyl
lower alkyl
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019870011259A
Other languages
English (en)
Korean (ko)
Other versions
KR880005089A (ko
Inventor
노리오 다까무라
구니유끼 오다
신이찌 고다또
이사오 야마구찌
고지 야노
Original Assignee
다나베 세이야꾸 가부시끼가이샤
아다찌 게이지로
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 다나베 세이야꾸 가부시끼가이샤, 아다찌 게이지로 filed Critical 다나베 세이야꾸 가부시끼가이샤
Publication of KR880005089A publication Critical patent/KR880005089A/ko
Application granted granted Critical
Publication of KR920002296B1 publication Critical patent/KR920002296B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019870011259A 1986-10-13 1987-10-12 펜옥시아세트산 유도체 및 이의 제조방법 Expired KR920002296B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP?61-242802 1986-10-13
JP242802 1986-10-13
JP24280286 1986-10-13

Publications (2)

Publication Number Publication Date
KR880005089A KR880005089A (ko) 1988-06-28
KR920002296B1 true KR920002296B1 (ko) 1992-03-21

Family

ID=17094503

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870011259A Expired KR920002296B1 (ko) 1986-10-13 1987-10-12 펜옥시아세트산 유도체 및 이의 제조방법

Country Status (17)

Country Link
US (1) US4853404A (https=)
EP (1) EP0268800B1 (https=)
JP (1) JPS63225359A (https=)
KR (1) KR920002296B1 (https=)
CN (1) CN1014787B (https=)
AT (1) ATE72429T1 (https=)
AU (1) AU595385B2 (https=)
CA (1) CA1311483C (https=)
DE (1) DE3776627D1 (https=)
DK (1) DK166879B1 (https=)
ES (1) ES2032284T3 (https=)
FI (1) FI91402C (https=)
GR (1) GR3003727T3 (https=)
HK (1) HK47193A (https=)
HU (1) HU202501B (https=)
IE (1) IE60044B1 (https=)
IL (1) IL84106A (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2613720B1 (fr) * 1987-04-10 1990-01-19 Esteve Labor Dr Derives d'aryl-heteroaryl carbinols avec activite analgesique
JPH01316317A (ja) * 1988-03-10 1989-12-21 Tanabe Seiyaku Co Ltd 降圧剤
US4956379A (en) * 1990-02-13 1990-09-11 Bristol-Myers Squibb Company Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
EP0442448A3 (en) 1990-02-13 1992-08-12 Bristol-Myers Squibb Company Heterocyclic carboxylic acids and esters
US20040067531A1 (en) * 1997-08-20 2004-04-08 Sugen, Inc. Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
SI1255752T1 (sl) * 2000-02-15 2007-12-31 Pharmacia & Upjohn Co Llc S pirolom substituirani zaviralci 2-indolinon protein kinaza
AR042586A1 (es) 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
WO2003031438A1 (en) 2001-10-10 2003-04-17 Sugen, Inc. 3-[4-(substituted heterocyclyl)-pyrrol-2-ylmethylidene]-2-indolinone derivatives as kinase inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342851A (en) * 1964-10-30 1967-09-19 Merck & Co Inc Esters of [(2-methyleneacyl)phenoxy]-carboxylic acids and a method for their preparation
GB1415295A (en) * 1971-10-14 1975-11-26 Orchimed Sa Substituted phenoxy-alkyl-carboxylic acids and derivatives thereof
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
US4107179A (en) * 1977-08-22 1978-08-15 Smithkline Corporation Method for preparing ticrynafen
GB2024209B (en) * 1978-05-31 1982-09-08 Sori Soc Rech Ind Phenoxalkylcarboxylic acids
US4323691A (en) * 1979-10-09 1982-04-06 Abbott Laboratories Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters

Also Published As

Publication number Publication date
GR3003727T3 (https=) 1993-03-16
EP0268800A1 (en) 1988-06-01
US4853404A (en) 1989-08-01
CN1014787B (zh) 1991-11-20
DK166879B1 (da) 1993-07-26
KR880005089A (ko) 1988-06-28
AU595385B2 (en) 1990-03-29
JPH0544944B2 (https=) 1993-07-07
CA1311483C (en) 1992-12-15
ES2032284T3 (es) 1993-02-01
FI91402B (fi) 1994-03-15
CN87106895A (zh) 1988-04-20
HK47193A (en) 1993-05-21
FI874473A0 (fi) 1987-10-12
AU7956387A (en) 1988-04-14
JPS63225359A (ja) 1988-09-20
DK532987D0 (da) 1987-10-12
DK532987A (da) 1988-04-14
FI91402C (fi) 1994-06-27
DE3776627D1 (de) 1992-03-19
EP0268800B1 (en) 1992-02-05
IE60044B1 (en) 1994-05-18
IE872668L (en) 1988-04-13
ATE72429T1 (de) 1992-02-15
HU202501B (en) 1991-03-28
IL84106A0 (en) 1988-03-31
IL84106A (en) 1991-07-18
FI874473L (fi) 1988-04-14
HUT50788A (en) 1990-03-28

Similar Documents

Publication Publication Date Title
US4812570A (en) Method for producing thiazolidinedione derivatives
US4792561A (en) Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors
US4921862A (en) Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors
JPH08809B2 (ja) 中間体化合物及びその製造方法
KR920002296B1 (ko) 펜옥시아세트산 유도체 및 이의 제조방법
US4973600A (en) Benzodioxole derivatives, pharmaceutical compositions and use
US4464361A (en) Adenosine derivatives
US4415736A (en) Certain tetrahydropyridine intermediates
US4604457A (en) 2-substituted cephem derivatives and process for preparing the same
US4868301A (en) Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
JP2731853B2 (ja) トリ低級アルカノイルオキシホウ素の製造法
SE448459B (sv) 4a,9b-trans-hexahydro-gamma-karbolinforeningar som mellanprodukter for framstellning av hexahydro-gamma-karbolinforeningar
Bourlot et al. A straightforward route to 4H‐1, 4‐Benzoxazine‐2‐carbaldehydes by swern oxidation
EP0397210A1 (en) Indole derivative and method of production thereof
US4565869A (en) Dicarbamates
US4528372A (en) N-Phthalidyl-5-fluorouracils
US4891433A (en) Process for the preparation of dibenzothiepin derivative
KR920005417B1 (ko) 디벤조티에핀 유도체의 제조방법
US4900844A (en) Intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains
US4692528A (en) Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
US4421916A (en) Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
US4260544A (en) Halogenomethylene-indoxyls
US4537963A (en) Intermediates for octahydrobenzofuro[3,2-E]isoquinolines
US4579952A (en) Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
US4260545A (en) N-Substituted halogenomethyleneindoxyls

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

G160 Decision to publish patent application
PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 19950322

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 19950322

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

R18-X000 Changes to party contact information recorded

St.27 status event code: A-5-5-R10-R18-oth-X000

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301