DE3776627D1 - Phenoxyessigsaeure-derivate und verfahren zu deren herstellung. - Google Patents

Phenoxyessigsaeure-derivate und verfahren zu deren herstellung.

Info

Publication number
DE3776627D1
DE3776627D1 DE8787114877T DE3776627T DE3776627D1 DE 3776627 D1 DE3776627 D1 DE 3776627D1 DE 8787114877 T DE8787114877 T DE 8787114877T DE 3776627 T DE3776627 T DE 3776627T DE 3776627 D1 DE3776627 D1 DE 3776627D1
Authority
DE
Germany
Prior art keywords
production
group
phenoxy acetic
salt
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787114877T
Other languages
English (en)
Inventor
Norio Takamura
Kuniyuki Oda
Shinichi Kodato
Isao Yamaguchi
Koji Yano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Application granted granted Critical
Publication of DE3776627D1 publication Critical patent/DE3776627D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8787114877T 1986-10-13 1987-10-12 Phenoxyessigsaeure-derivate und verfahren zu deren herstellung. Expired - Fee Related DE3776627D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24280286 1986-10-13

Publications (1)

Publication Number Publication Date
DE3776627D1 true DE3776627D1 (de) 1992-03-19

Family

ID=17094503

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787114877T Expired - Fee Related DE3776627D1 (de) 1986-10-13 1987-10-12 Phenoxyessigsaeure-derivate und verfahren zu deren herstellung.

Country Status (17)

Country Link
US (1) US4853404A (de)
EP (1) EP0268800B1 (de)
JP (1) JPS63225359A (de)
KR (1) KR920002296B1 (de)
CN (1) CN1014787B (de)
AT (1) ATE72429T1 (de)
AU (1) AU595385B2 (de)
CA (1) CA1311483C (de)
DE (1) DE3776627D1 (de)
DK (1) DK166879B1 (de)
ES (1) ES2032284T3 (de)
FI (1) FI91402C (de)
GR (1) GR3003727T3 (de)
HK (1) HK47193A (de)
HU (1) HU202501B (de)
IE (1) IE60044B1 (de)
IL (1) IL84106A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2613720B1 (fr) * 1987-04-10 1990-01-19 Esteve Labor Dr Derives d'aryl-heteroaryl carbinols avec activite analgesique
JPH01316317A (ja) * 1988-03-10 1989-12-21 Tanabe Seiyaku Co Ltd 降圧剤
US4956379A (en) * 1990-02-13 1990-09-11 Bristol-Myers Squibb Company Pyrazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
CA2036192A1 (en) 1990-02-13 1991-08-14 Nicholas Meanwell Heterocyclic carboxylic acids and esters
US20040067531A1 (en) * 1997-08-20 2004-04-08 Sugen, Inc. Methods of modulating protein tyrosine kinase function with substituted indolinone compounds
UA73976C2 (uk) * 2000-02-15 2005-10-17 Суджен, Інк. Заміщені піролом 2-індолінони, фармацевтична композиція, спосіб модуляції каталітичної активності протеїнкінази та спосіб лікування або профілактики захворювання, пов'язаного з протеїнкіназою
AR042586A1 (es) * 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
JP2005508953A (ja) 2001-10-10 2005-04-07 スージェン・インコーポレーテッド キナーゼ阻害剤としての3−[4−(置換ヘテロサイクリル)−ピロール−2−イルメチリデン]−2−インドリノン誘導体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342851A (en) * 1964-10-30 1967-09-19 Merck & Co Inc Esters of [(2-methyleneacyl)phenoxy]-carboxylic acids and a method for their preparation
CH543472A (fr) * 1969-01-31 1973-10-31 Orchimed Sa Procédé pour la préparation d'acides phénoxyalcoyl-carboxyliques
GB1415295A (en) * 1971-10-14 1975-11-26 Orchimed Sa Substituted phenoxy-alkyl-carboxylic acids and derivatives thereof
US4107179A (en) * 1977-08-22 1978-08-15 Smithkline Corporation Method for preparing ticrynafen
GB2024209B (en) * 1978-05-31 1982-09-08 Sori Soc Rech Ind Phenoxalkylcarboxylic acids
US4323691A (en) * 1979-10-09 1982-04-06 Abbott Laboratories Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters

Also Published As

Publication number Publication date
CA1311483C (en) 1992-12-15
HU202501B (en) 1991-03-28
KR920002296B1 (ko) 1992-03-21
US4853404A (en) 1989-08-01
IL84106A0 (en) 1988-03-31
JPH0544944B2 (de) 1993-07-07
FI91402C (fi) 1994-06-27
HK47193A (en) 1993-05-21
GR3003727T3 (de) 1993-03-16
IE60044B1 (en) 1994-05-18
AU7956387A (en) 1988-04-14
EP0268800B1 (de) 1992-02-05
FI874473A0 (fi) 1987-10-12
AU595385B2 (en) 1990-03-29
DK166879B1 (da) 1993-07-26
ES2032284T3 (es) 1993-02-01
EP0268800A1 (de) 1988-06-01
IE872668L (en) 1988-04-13
FI91402B (fi) 1994-03-15
DK532987A (da) 1988-04-14
CN87106895A (zh) 1988-04-20
ATE72429T1 (de) 1992-02-15
DK532987D0 (da) 1987-10-12
IL84106A (en) 1991-07-18
CN1014787B (zh) 1991-11-20
HUT50788A (en) 1990-03-28
FI874473A (fi) 1988-04-14
JPS63225359A (ja) 1988-09-20
KR880005089A (ko) 1988-06-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee