KR910007881A - 아미노피리디닐아미노페놀 및 관련화합물, 이들의 제조방법 및 중간체 및 약제로서의 이들의 용도 - Google Patents

아미노피리디닐아미노페놀 및 관련화합물, 이들의 제조방법 및 중간체 및 약제로서의 이들의 용도 Download PDF

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Publication number
KR910007881A
KR910007881A KR1019900016854A KR900016854A KR910007881A KR 910007881 A KR910007881 A KR 910007881A KR 1019900016854 A KR1019900016854 A KR 1019900016854A KR 900016854 A KR900016854 A KR 900016854A KR 910007881 A KR910007881 A KR 910007881A
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KR
South Korea
Prior art keywords
compound
lower alkyl
hydrogen
formula
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019900016854A
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English (en)
Korean (ko)
Inventor
챨스 알렌 리챠드
토마스 클레인 조셉
챨스 에플랜드 리챠드
Original Assignee
제이 티. 쉐크. 쥬니어
훽스트-럿셀 파마슈티칼즈 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by 제이 티. 쉐크. 쥬니어, 훽스트-럿셀 파마슈티칼즈 인코포레이티드 filed Critical 제이 티. 쉐크. 쥬니어
Publication of KR910007881A publication Critical patent/KR910007881A/ko
Withdrawn legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019900016854A 1989-10-24 1990-10-22 아미노피리디닐아미노페놀 및 관련화합물, 이들의 제조방법 및 중간체 및 약제로서의 이들의 용도 Withdrawn KR910007881A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US425713 1989-10-24
US07/425,713 US4959378A (en) 1989-10-24 1989-10-24 Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Publications (1)

Publication Number Publication Date
KR910007881A true KR910007881A (ko) 1991-05-30

Family

ID=23687726

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900016854A Withdrawn KR910007881A (ko) 1989-10-24 1990-10-22 아미노피리디닐아미노페놀 및 관련화합물, 이들의 제조방법 및 중간체 및 약제로서의 이들의 용도

Country Status (12)

Country Link
US (1) US4959378A (enExample)
EP (1) EP0424848A3 (enExample)
JP (1) JPH03151364A (enExample)
KR (1) KR910007881A (enExample)
AU (1) AU6485790A (enExample)
CA (1) CA2028285A1 (enExample)
FI (1) FI905192A7 (enExample)
IE (1) IE903809A1 (enExample)
IL (1) IL96082A0 (enExample)
NO (1) NO904576L (enExample)
PT (1) PT95652A (enExample)
ZA (1) ZA908459B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990009985A1 (en) * 1989-02-23 1990-09-07 Otsuka Pharmaceutical Factory, Inc. p-AMINOPHENOL DERIVATIVE AND PRODUCTION AND APPLICATION THEREOF
US4959378A (en) * 1989-10-24 1990-09-25 Hoechst-Roussel Pharmaceuticals Inc. Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
MX2007004781A (es) * 2004-10-20 2007-05-11 Applied Research Systems Derivados de 3-arilamino piridina.
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB750925A (en) * 1953-10-26 1956-06-20 Wellcome Found Improvements in and relating to pyridine derivatives and the manufacture thereof
US3118884A (en) * 1959-10-19 1964-01-21 Schering Corp Derivatives of 3-azaphenothiazine and 3-azaphenoxazine
DE1795499A1 (de) * 1964-08-29 1972-02-10 Degussa Neue substituierte Diaminopyridine
DE1795544A1 (de) * 1964-08-29 1973-02-15 Degussa Verfahren zur herstellung von phenylamino-pyridinen
DE1568426A1 (de) * 1966-11-16 1970-04-02 Degussa Verfahren zur Herstellung von neuen N-aromatisch substituierten Saeureamiden
FR8363M (enExample) * 1967-02-01 1971-02-15
US3495969A (en) * 1967-09-25 1970-02-17 Mobil Oil Corp Substituted nitropyridines as herbicides
US3576616A (en) * 1969-05-15 1971-04-27 Monsanto Co Herbicidal compositions and methods
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
GB2073736B (en) * 1979-10-03 1984-02-01 Ici Ltd Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
US4959378A (en) * 1989-10-24 1990-09-25 Hoechst-Roussel Pharmaceuticals Inc. Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Also Published As

Publication number Publication date
CA2028285A1 (en) 1991-04-25
AU6485790A (en) 1991-05-02
FI905192A7 (fi) 1991-04-25
NO904576D0 (no) 1990-10-23
ZA908459B (en) 1991-08-28
IL96082A0 (en) 1991-07-18
US4959378A (en) 1990-09-25
US4959378B1 (enExample) 1993-08-10
FI905192A0 (fi) 1990-10-22
PT95652A (pt) 1991-09-13
EP0424848A3 (en) 1991-10-02
NO904576L (no) 1991-04-25
EP0424848A2 (en) 1991-05-02
IE903809A1 (en) 1991-04-24
JPH03151364A (ja) 1991-06-27

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19901022

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid