FI905192A7 - Aminopyridinyyliaminofenolit ja vastaavat yhdisteet, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö lääkkeinä - Google Patents

Aminopyridinyyliaminofenolit ja vastaavat yhdisteet, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö lääkkeinä Download PDF

Info

Publication number
FI905192A7
FI905192A7 FI905192A FI905192A FI905192A7 FI 905192 A7 FI905192 A7 FI 905192A7 FI 905192 A FI905192 A FI 905192A FI 905192 A FI905192 A FI 905192A FI 905192 A7 FI905192 A7 FI 905192A7
Authority
FI
Finland
Prior art keywords
aminopyridinylaminophenols
pharmaceuticals
intermediates
preparation
similar compounds
Prior art date
Application number
FI905192A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI905192A0 (fi
Inventor
Richard Charles Allen
Joseph Thomas Klein
Richard Charles Effland
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI905192A0 publication Critical patent/FI905192A0/fi
Publication of FI905192A7 publication Critical patent/FI905192A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI905192A 1989-10-24 1990-10-22 Aminopyridinyyliaminofenolit ja vastaavat yhdisteet, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö lääkkeinä FI905192A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/425,713 US4959378A (en) 1989-10-24 1989-10-24 Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Publications (2)

Publication Number Publication Date
FI905192A0 FI905192A0 (fi) 1990-10-22
FI905192A7 true FI905192A7 (fi) 1991-04-25

Family

ID=23687726

Family Applications (1)

Application Number Title Priority Date Filing Date
FI905192A FI905192A7 (fi) 1989-10-24 1990-10-22 Aminopyridinyyliaminofenolit ja vastaavat yhdisteet, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö lääkkeinä

Country Status (12)

Country Link
US (1) US4959378A (enExample)
EP (1) EP0424848A3 (enExample)
JP (1) JPH03151364A (enExample)
KR (1) KR910007881A (enExample)
AU (1) AU6485790A (enExample)
CA (1) CA2028285A1 (enExample)
FI (1) FI905192A7 (enExample)
IE (1) IE903809A1 (enExample)
IL (1) IL96082A0 (enExample)
NO (1) NO904576L (enExample)
PT (1) PT95652A (enExample)
ZA (1) ZA908459B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2027584A1 (en) * 1989-02-23 1990-08-24 Kiyoto Goto P-aminophenol derivatives, and processes for production of and uses for the same
US4959378A (en) * 1989-10-24 1990-09-25 Hoechst-Roussel Pharmaceuticals Inc. Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders
US6022884A (en) * 1997-11-07 2000-02-08 Amgen Inc. Substituted pyridine compounds and methods of use
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
AR051248A1 (es) * 2004-10-20 2007-01-03 Applied Research Systems Derivados de 3-arilamino piridina
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白(rap)-缀合物对肝病症的治疗
DK3395372T3 (da) 2009-02-20 2022-04-19 Enhanx Biopharm Inc System til afgivelse af glutathion-baseret medikament
CN110075069A (zh) 2009-05-06 2019-08-02 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB750925A (en) * 1953-10-26 1956-06-20 Wellcome Found Improvements in and relating to pyridine derivatives and the manufacture thereof
US3118884A (en) * 1959-10-19 1964-01-21 Schering Corp Derivatives of 3-azaphenothiazine and 3-azaphenoxazine
DE1795544A1 (de) * 1964-08-29 1973-02-15 Degussa Verfahren zur herstellung von phenylamino-pyridinen
DE1795499A1 (de) * 1964-08-29 1972-02-10 Degussa Neue substituierte Diaminopyridine
DE1568426A1 (de) * 1966-11-16 1970-04-02 Degussa Verfahren zur Herstellung von neuen N-aromatisch substituierten Saeureamiden
FR8363M (enExample) * 1967-02-01 1971-02-15
US3495969A (en) * 1967-09-25 1970-02-17 Mobil Oil Corp Substituted nitropyridines as herbicides
US3576616A (en) * 1969-05-15 1971-04-27 Monsanto Co Herbicidal compositions and methods
US3721676A (en) * 1969-11-12 1973-03-20 Merck & Co Inc Certain 3-amino-2(1h)pyridones
GB2073736B (en) * 1979-10-03 1984-02-01 Ici Ltd Process for preparing pyridinyloxyphenoxy compounds and derivatives thereof
IE56702B1 (en) * 1982-12-01 1991-11-06 Usv Pharma Corp Antiinflammatory antiallergic compounds
US4959378A (en) * 1989-10-24 1990-09-25 Hoechst-Roussel Pharmaceuticals Inc. Aminopyridinylaminophenol compounds useful as topical antiinflammatory agents for the treatment of skin disorders

Also Published As

Publication number Publication date
US4959378B1 (enExample) 1993-08-10
IL96082A0 (en) 1991-07-18
NO904576D0 (no) 1990-10-23
IE903809A1 (en) 1991-04-24
PT95652A (pt) 1991-09-13
JPH03151364A (ja) 1991-06-27
KR910007881A (ko) 1991-05-30
US4959378A (en) 1990-09-25
EP0424848A3 (en) 1991-10-02
EP0424848A2 (en) 1991-05-02
CA2028285A1 (en) 1991-04-25
AU6485790A (en) 1991-05-02
FI905192A0 (fi) 1990-10-22
ZA908459B (en) 1991-08-28
NO904576L (no) 1991-04-25

Similar Documents

Publication Publication Date Title
FI904419A7 (fi) 3-(1-substituoituja-4-piperatsinyyli)-1H-indatsoleja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI903215A7 (fi) Heteroaryyliamino- ja heteroaryylioksipyridiiniamiineja ja niihin liittyviä yhdisteitä, menetelmä niiden valmistamiseksi sekä niiden käyttö lääkkeinä
FI904327A7 (fi) N-substituoitu-4-pyrimidiiniamiineja ja -pyrimidiinidiamiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI942074L (fi) nor-sappijohdannaisia, menetelmä niiden valmistamiseksi ja näiden yhdisteiden käyttö lääkeaineina
FI902248A7 (fi) N-heteroaryyli-4-kinoliiniamiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI964395L (fi) Uudet erytromysiinijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI830378A7 (fi) Pyratsolioksatsiinit, -tiatsiinit, - kinoliinit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeainlääkeaineina.
FI902734A7 (fi) 2-hydroksi-n-propyyliamiinit, näitä yhdisteitä sisältävät lääkeaineet ja menetelmä niiden valmistamiseksi
FI940810L (fi) Substituoidut bentseenisulfonyylivirtsa-aineet ja -tiovirtsa-aineet, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI902850A7 (fi) N-heteroaryylipuriini-6-amiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineina
FI884806A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten substituoitujen tetraliinien, kromaanien ja niitä läheisesti muistuttavien yhdisteiden valmistamiseksi sekä menetelmässä käyttökelpoisia välituotteita
FI885488A0 (fi) 2,2-difluorisyklopropyylietaanijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö tuholaisten torjunta-aineina
FI905192A7 (fi) Aminopyridinyyliaminofenolit ja vastaavat yhdisteet, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI950817A7 (fi) Uudet bentsodioksaaniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FI903214A7 (fi) Naftyyliamino- ja naftyylioksi-pyrimidiinit ja niihin liittyvät yhdisteet, menetelmä niiden valmistamiseksi ja niiden käyttö dermatologisinalääkeaineina
FI962587A7 (fi) 1,3-oksatsin-4-onijohdannaiset, menetelmä ja välituotteet niiden valmistamiseksi ja niiden käyttö herbisideinä
FI971081L (fi) Triatsolopyridatsiinit, menetelmä ja välituotteet niiden valmistamiseksi sekä niiden käyttö lääkeaineina
FI895288A7 (fi) 1,2,3,4-tetrahydro-1,9-akridiiniamiineja, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
BR8803768A (pt) Composicao odorante,processo para producao de compostos e uso dos ditos compostos
FI941094L (fi) Uudet erytromysiinijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
FI905173A7 (fi) Diatsabisykloamiiniyhdisteet ja menetelmä niiden valmistamiseksi
FI896243A7 (fi) N-pyridinyyli-9H-karbatsoli-9-amiineja, menetelmä niiden valmistamiseksi sekä niiden käyttö lääkkeinä
FI924053A7 (fi) Substituoidut aminopropaanit, menetelmä niiden valmistamiseksi ja niiden käyttö
FI870315A0 (fi) Välituotteita -laktaami-yhdisteiden sekä 1 -metyylikarbapeneemi-yhdisteiden synteeseissä, ja näiden valmistusmenetelmä
FI902852A7 (fi) Reniinin vaikutusta estävät peptidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkeaineina

Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED