KR890701724A - 아세테이트 저생성 능력을 갖는 미생물 및 그것을 사용한 유용물질의 생성방법 - Google Patents

아세테이트 저생성 능력을 갖는 미생물 및 그것을 사용한 유용물질의 생성방법

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KR890701724A
KR890701724A KR1019890701272A KR890701272A KR890701724A KR 890701724 A KR890701724 A KR 890701724A KR 1019890701272 A KR1019890701272 A KR 1019890701272A KR 890701272 A KR890701272 A KR 890701272A KR 890701724 A KR890701724 A KR 890701724A
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South Korea
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coli
biotin
producing
microorganisms
same
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KR1019890701272A
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KR910005626B1 (ko
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신이치로 하즈
오지 이후쿠
지로 기시모토
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후쿠하라 요시하루
가부시기가이샤 시세이도
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Publication of KR890701724A publication Critical patent/KR890701724A/ko
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/185—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system
    • C12P17/186—Heterocyclic compounds containing sulfur atoms as ring hetero atoms in the condensed system containing a 2-oxo-thieno[3,4-d]imidazol nucleus, e.g. Biotin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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    • C12N1/205—Bacterial isolates
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12P21/00—Preparation of peptides or proteins
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    • C—CHEMISTRY; METALLURGY
    • C21—METALLURGY OF IRON
    • C21B—MANUFACTURE OF IRON OR STEEL
    • C21B13/00—Making spongy iron or liquid steel, by direct processes
    • C21B13/0006—Making spongy iron or liquid steel, by direct processes obtaining iron or steel in a molten state
    • C21B13/0013—Making spongy iron or liquid steel, by direct processes obtaining iron or steel in a molten state introduction of iron oxide into a bath of molten iron containing a carbon reductant
    • C21B13/002—Reduction of iron ores by passing through a heated column of carbon
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  • Chemical & Material Sciences (AREA)
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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
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Abstract

내용 없음

Description

아세테이트 저생성 능력을 갖는 미생물 및 그것을 사용한 유용물질의 생성방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 실시예 3에 설명된 플라즈미드 pXBA 312의 제조공정을 기술하고 있다.

Claims (9)

  1. 아세테이트의 생성 능력이 야생주, 이.콜리에 배해 1/5 이하인 것을 특징으로 하는 이.콜리(E.coli).
  2. 제1항에 있어서, 유용물질의 생성에 관한 유전정보를 갖는 재조합 플라즈미드를 더 포함하는 이.콜리.
  3. 제1항에 있어서, 비오틴에 의한 티이드 백 억제가 제거된 이.콜리.
  4. 제1항에 있어서, 비오틴 생성 이.콜리로부터 수득된 비오틴 오페론을 갖는 재조합 플라즈미드를 포함하는 이.콜리.
  5. 제3항에 있어서, 비오틴 생성 이.콜리로부터 수득된 비오틴을 갖는 재조합 플라즈미드를 포함하는 이.콜리.
  6. 야생주 이.콜리에 비해 아세테이트 생성능역이 1/5이하이며 유동 물질의 생성에 관한 유전 정보를 갖는 제조합 플라즈미드를 함유하는 이.콜리를 고밀도로 배양하며；생성된 유용 물질을 회수하는 것을 특징으로 하는 유용물질의 제조방법.
  7. 제6항에 있어서, 유용 물질이 비오틴 또는 디티오비오틴인 방법.
  8. 제7항에 있어서, 이.콜리의 비오틴에 의한 피이드 백 억제를 제거한 방법.
  9. 제8항에 있어서, 이.콜리를 1 내지 10g/1의 알라닌을 함유한 배지중에서 배양한 방법.
    ※ 참고사항：최초출원 내용에 의하여 공개하는 것임.
KR1019890701272A 1987-11-07 1988-11-07 아세테이트 저생성 능력을 갖는 미생물 및 그것을 이용한 유용물질의 생성방법 KR910005626B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP62-281826 1987-11-07
JP28182687 1987-11-07
JP62/281826 1987-11-07
PCT/JP1988/001124 WO1989004365A1 (en) 1987-11-07 1988-11-07 Microorganism having low acetate forming capability and its application

Publications (2)

Publication Number Publication Date
KR890701724A true KR890701724A (ko) 1989-12-21
KR910005626B1 KR910005626B1 (ko) 1991-08-01

Family

ID=17644538

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890701272A KR910005626B1 (ko) 1987-11-07 1988-11-07 아세테이트 저생성 능력을 갖는 미생물 및 그것을 이용한 유용물질의 생성방법

Country Status (11)

Country Link
US (1) US5919662A (ko)
EP (1) EP0316229B1 (ko)
JP (1) JP2763119B2 (ko)
KR (1) KR910005626B1 (ko)
CN (1) CN1024809C (ko)
AU (1) AU602274B2 (ko)
CA (1) CA1322735C (ko)
DE (1) DE3888789T2 (ko)
ES (1) ES2061711T3 (ko)
NZ (1) NZ226875A (ko)
WO (1) WO1989004365A1 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1053217C (zh) * 1990-03-27 2000-06-07 资生堂株式会社 新的微生物以及利用这些微生物生产生物素同效维生素的方法
JP3006847B2 (ja) * 1990-03-27 2000-02-07 株式会社資生堂 新規微生物およびそれを用いるビオチン類の製造方法
KR100250692B1 (ko) * 1991-09-13 2000-04-01 후쿠하라 요시하루 바이오틴 오페론
WO1993014094A1 (en) * 1992-01-17 1993-07-22 Universal Foods Corporation Method for recovering biotin
JP3428078B2 (ja) * 1992-09-10 2003-07-22 住友化学工業株式会社 ビオチンの製造方法および使用される微生物
DE59308149D1 (de) * 1992-10-02 1998-03-19 Lonza Ag Biotechnologisches verfahren zur herstellung von biotin
US6277609B1 (en) 1993-01-06 2001-08-21 Basf Aktiengesellschaft Method to produce biotin
JP3629290B2 (ja) * 1993-10-01 2005-03-16 協和醗酵工業株式会社 物質の製造法
KR0151534B1 (ko) * 1995-10-30 1998-08-17 이종호 유기산 생성이 억제된 대장균 변이주
WO2002074952A2 (de) * 2001-03-16 2002-09-26 Rina Netzwerk Rna-Technologien Gmbh Gegen abbau stabilisierte nukleinsäure
WO2004085613A2 (en) * 2003-03-19 2004-10-07 Stratagene Electrocompetent host cells
JP4700357B2 (ja) * 2005-01-26 2011-06-15 中部電力株式会社 開閉器用ブッシングにおける端子カバー支持部材の固定構造体
TWI389645B (zh) * 2005-05-25 2013-03-21 Suntory Holdings Ltd The method of treating raw beans with controlled pH
EP2119789A1 (en) 2008-05-16 2009-11-18 Université Libre de Bruxelles Hyperproliferative recombinant cell
JP5599171B2 (ja) * 2009-08-07 2014-10-01 花王株式会社 ドデカヒドロ−３ａ，６，６，９ａ−テトラメチルナフト［２，１−ｂ］フラン合成中間体高生産性変異微生物
WO2011144739A1 (en) 2010-05-20 2011-11-24 Universite Libre De Bruxelles Hyperproliferative recombinant cell
WO2015178465A1 (ja) * 2014-05-21 2015-11-26 味の素株式会社 フィブロイン様タンパク質の製造法
JP7057558B2 (ja) * 2015-11-25 2022-04-20 味の素株式会社 フィブロイン様タンパク質の製造法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0740922B2 (ja) * 1985-03-05 1995-05-10 株式会社資生堂 ビオチン生産性微生物
JPH07110232B2 (ja) * 1985-10-14 1995-11-29 株式会社日立製作所 遺伝子組換え大腸菌の遺伝子生産物を採取する方法および装置
JPS62155081A (ja) * 1985-12-27 1987-07-10 Shiseido Co Ltd 新規微生物およびそれを用いる醗酵法によるビオチンの製造法

Also Published As

Publication number Publication date
EP0316229B1 (en) 1994-03-30
JPH02502065A (ja) 1990-07-12
JP2763119B2 (ja) 1998-06-11
CN1024809C (zh) 1994-06-01
AU2614688A (en) 1989-06-01
AU602274B2 (en) 1990-10-04
KR910005626B1 (ko) 1991-08-01
ES2061711T3 (es) 1994-12-16
CN1033646A (zh) 1989-07-05
DE3888789T2 (de) 1994-08-18
CA1322735C (en) 1993-10-05
DE3888789D1 (de) 1994-05-05
EP0316229A1 (en) 1989-05-17
WO1989004365A1 (en) 1989-05-18
US5919662A (en) 1999-07-06
NZ226875A (en) 1990-09-26

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