KR890700341A - 저독성 약물-지질계 - Google Patents

저독성 약물-지질계

Info

Publication number
KR890700341A
KR890700341A KR1019880701402A KR880701402A KR890700341A KR 890700341 A KR890700341 A KR 890700341A KR 1019880701402 A KR1019880701402 A KR 1019880701402A KR 880701402 A KR880701402 A KR 880701402A KR 890700341 A KR890700341 A KR 890700341A
Authority
KR
South Korea
Prior art keywords
lipid
compositions
hdlcs
lipid complexes
drug
Prior art date
Application number
KR1019880701402A
Other languages
English (en)
Other versions
KR970002870B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27361805&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR890700341(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of KR890700341A publication Critical patent/KR890700341A/ko
Application granted granted Critical
Publication of KR970002870B1 publication Critical patent/KR970002870B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B2227/00—Photographic printing apparatus
    • G03B2227/32—Projection printing apparatus, e.g. enlarging apparatus, copying camera
    • G03B2227/325—Microcapsule copiers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Vehicle Step Arrangements And Article Storage (AREA)
  • Catalysts (AREA)
  • Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
KR1019880701402A 1987-03-05 1988-03-03 저독성 약물-지질계 KR970002870B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US2215787A 1987-03-05 1987-03-05
US022,157 1987-03-05
US069,908 1987-06-06
US6990887A 1987-07-06 1987-07-06
US7930987A 1987-07-29 1987-07-29
PCT/US1988/000647 WO1988006443A1 (en) 1987-03-05 1988-03-03 Low toxicity drug-lipid systems
US079,309 1988-03-07

Publications (2)

Publication Number Publication Date
KR890700341A true KR890700341A (ko) 1989-04-24
KR970002870B1 KR970002870B1 (ko) 1997-03-12

Family

ID=27361805

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880701402A KR970002870B1 (ko) 1987-03-05 1988-03-03 저독성 약물-지질계

Country Status (20)

Country Link
EP (1) EP0282405B2 (ko)
KR (1) KR970002870B1 (ko)
CN (1) CN1044093C (ko)
AT (1) ATE118169T1 (ko)
AU (1) AU622405B2 (ko)
CA (1) CA1338701C (ko)
DE (1) DE3852961T3 (ko)
DK (1) DK176010B1 (ko)
ES (1) ES2070131T5 (ko)
FI (1) FI102724B1 (ko)
GR (1) GR3015916T3 (ko)
HK (1) HK1007495A1 (ko)
IE (1) IE67152B1 (ko)
IL (1) IL85607A (ko)
LU (1) LU88684I2 (ko)
NL (1) NL990004I1 (ko)
NO (4) NO179995C (ko)
NZ (1) NZ223660A (ko)
PT (1) PT86913B (ko)
WO (1) WO1988006443A1 (ko)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
AU598958B2 (en) 1987-11-12 1990-07-05 Vestar, Inc. Improved amphotericin b liposome preparation
DE69026820T2 (de) * 1989-03-31 1996-11-28 Univ California Zubereitung von liposomen- und lipid-komplexzusammensetzungen
US5188951A (en) * 1990-04-17 1993-02-23 The Liposome Company, Inc. Enzymatic synthesis of soluble phosphatides from phospholipids
US5556637A (en) * 1990-08-06 1996-09-17 A. Nattermann & Cie. Gmbh Water containing liposome system
DE4108903A1 (de) * 1990-08-06 1992-02-13 Nattermann A & Cie Pharmazeutisches produkt
WO1992007571A1 (fr) * 1990-11-06 1992-05-14 Nippon Shinyaku Co., Ltd. Procede de production d'une emulsion grasse
US5534502A (en) * 1990-11-06 1996-07-09 Nippon Shinyaku Co. Ltd. Process for producing fat emulsion
EP0599977A1 (en) * 1991-08-14 1994-06-08 SEQUUS PHARMACEUTICALS, INC. (a Delaware Corporation) Hiv-treatment method with low-toxicity amphotericin b
ES2193005T1 (es) * 1993-05-21 2003-11-01 Elan Pharm Inc Reduccion de reacciones fisiologicas adversas inducidas por liposomas.
US5716526A (en) * 1994-01-14 1998-02-10 The Liposome Company, Inc. Method of separating materials from liposomes or lipid complexes
US5902604A (en) 1995-06-06 1999-05-11 Board Of Regents, The University Of Texas System Submicron liposome suspensions obtained from preliposome lyophilizates
GB2326337A (en) 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US6165997A (en) * 1997-11-20 2000-12-26 Statens Serum Institut Phospholipids having antimicrobial activity with or without the presence of antimicrobials
BRPI0619565A2 (pt) * 2005-12-08 2011-10-04 Wyeth Corp composições lipossÈmicas
KR101132626B1 (ko) * 2009-10-12 2012-04-02 주식회사 녹십자 난용성 약물의 전달을 위한 고밀도지단백 나노입자의 제조방법
CN103179951B (zh) 2010-08-20 2016-01-20 雷迪博士实验室有限公司 磷脂储库
DK2629779T3 (en) 2010-10-22 2017-10-02 Dr Reddy's Laboratories Sa Use of stock stable viscous phospholipid depot for wound treatment
CA2871820C (en) 2012-05-10 2020-11-03 Painreform Ltd. Depot formulations of a hydrophobic active ingredient and methods for preparation thereof
WO2016205384A1 (en) 2015-06-15 2016-12-22 The University Of Washington Multiple drug lipid nanoparticle composition and related methods for extended drug levels in blood and lymph tissue

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310506A (en) * 1979-02-22 1982-01-12 California Institute Of Technology Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
US4604376A (en) * 1982-04-21 1986-08-05 Research Corporation Enteric compounds and complexes
US4436746A (en) * 1982-09-30 1984-03-13 Ciba-Geigy Corporation Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
IL78929A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
IL78930A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Lyophilized emulsion compositions for parenteral administration

Also Published As

Publication number Publication date
ES2070131T5 (es) 1998-10-01
NO1998012I1 (no) 1998-03-25
NO944071D0 (no) 1994-10-26
NO944071L (no) 1988-11-24
AU622405B2 (en) 1992-04-09
NO179995B (no) 1996-10-21
EP0282405B1 (en) 1995-02-08
DE3852961T2 (de) 1995-07-06
PT86913A (pt) 1989-03-30
FI894161A0 (fi) 1989-09-04
DK98089A (da) 1989-03-01
IE880600L (en) 1988-09-05
GR3015916T3 (en) 1995-07-31
NZ223660A (en) 1990-11-27
KR970002870B1 (ko) 1997-03-12
PT86913B (pt) 1993-07-30
LU88684I2 (fr) 1996-04-29
ATE118169T1 (de) 1995-02-15
HK1007495A1 (en) 1999-04-16
NO1998013I1 (no) 1998-03-25
NO884391D0 (no) 1988-10-04
FI102724B (fi) 1999-02-15
IE67152B1 (en) 1996-03-06
NO884391L (no) 1988-11-24
FI102724B1 (fi) 1999-02-15
CA1338701C (en) 1996-11-12
CN1044093C (zh) 1999-07-14
EP0282405A2 (en) 1988-09-14
NO180147B (no) 1996-11-18
IL85607A0 (en) 1988-08-31
DK98089D0 (da) 1989-03-01
CN88101864A (zh) 1988-09-28
NL990004I1 (nl) 1999-04-01
WO1988006443A1 (en) 1988-09-07
DK176010B1 (da) 2005-11-28
ES2070131T3 (es) 1995-06-01
DE3852961D1 (de) 1995-03-23
EP0282405B2 (en) 1998-07-22
EP0282405A3 (en) 1989-01-04
AU1799088A (en) 1988-09-26
NO180147C (no) 1997-02-26
NO179995C (no) 1997-01-29
DE3852961T3 (de) 1998-12-24
IL85607A (en) 1992-08-18

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Legal Events

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E902 Notification of reason for refusal
E902 Notification of reason for refusal
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20120103

Year of fee payment: 15

EXPY Expiration of term