US5721365A
(en)
*
|
1989-09-15 |
1998-02-24 |
Us Health |
N-substituted piperazine NONOates
|
US5208233A
(en)
*
|
1989-09-15 |
1993-05-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
|
US5039705A
(en)
*
|
1989-09-15 |
1991-08-13 |
The United States Of America As Represented By The Department Of Health And Human Services |
Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
|
US5262569A
(en)
*
|
1991-07-17 |
1993-11-16 |
Rohm And Haas Company |
Salts of N-nitrosophenylhydroxylamine
|
US5185376A
(en)
*
|
1991-09-24 |
1993-02-09 |
The United States Of America As Represented By The Department Of Health And Human Services |
Therapeutic inhibition of platelet aggregation by nucleophile-nitric oxide complexes and derivatives thereof
|
DE69223157T2
(de)
*
|
1991-09-24 |
1998-06-10 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Bethesda, Md. |
Sauerstoff-substituierte derivate von nucleophil-stickstoffoxid-addukten und ihre verwendung als stickstoffoxid-donor-prodrugs
|
US5814666A
(en)
*
|
1992-04-13 |
1998-09-29 |
The United States As Represented By The Department Of Health And Human Services |
Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents
|
AU3969793A
(en)
*
|
1992-04-13 |
1993-11-18 |
United States Of America, Represented By The Secretary, Department Of Health And Human Services, The |
Use of nitric oxide/nucleophile complexes for the treatment of cancer
|
US5650447A
(en)
*
|
1992-08-24 |
1997-07-22 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Nitric oxide-releasing polymers to treat restenosis and related disorders
|
US5632981A
(en)
*
|
1992-08-24 |
1997-05-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
|
US5910316A
(en)
|
1992-08-24 |
1999-06-08 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Use of nitric oxide-releasing agents to treat impotency
|
US5691423A
(en)
*
|
1992-08-24 |
1997-11-25 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polysaccharide-bound nitric oxide-nucleophile adducts
|
US6255277B1
(en)
|
1993-09-17 |
2001-07-03 |
Brigham And Women's Hospital |
Localized use of nitric oxide-adducts to prevent internal tissue damage
|
WO1995009612A1
(en)
*
|
1993-10-07 |
1995-04-13 |
Entremed, Inc. |
Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents
|
DE69425331D1
(de)
*
|
1993-10-08 |
2000-08-24 |
Us Health |
Verwendung von stickstoffoxid freisetzenden verbindungen als arzneimittel zur strahlungssensibilisation fur hypoxische zellen
|
US5840759A
(en)
*
|
1993-10-08 |
1998-11-24 |
The United States Of America As Represented By The Department Of Health And Human Services |
Use of nitric oxide releasing compounds to protect noncancerous cells from chemotherapeutic agents
|
DE69424560T2
(de)
*
|
1993-11-02 |
2001-01-18 |
The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College, Baton Rouge |
Verwendung von stickstoffoxid freisetzenden verbindungen zur herstellung eines arzneimittels zum schutz gegen die ischämischen reperfusionsschäden
|
HU218280B
(en)
*
|
1994-04-26 |
2000-07-28 |
|
Cyclodextrin inclusion complexes containing sin-1a which are stable intheir solid state, process for their preparation and pharmaceutical compositions containing the comlexes
|
US5519020A
(en)
*
|
1994-10-28 |
1996-05-21 |
The University Of Akron |
Polymeric wound healing accelerators
|
US5700830A
(en)
*
|
1994-11-22 |
1997-12-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Use of nitric oxide-releasing agents for reducing metastasis risk
|
US5665077A
(en)
*
|
1995-04-24 |
1997-09-09 |
Nitrosci Pharmaceuticals Llc |
Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis
|
US5698738A
(en)
*
|
1995-05-15 |
1997-12-16 |
Board Of Regents, The University Of Texas System |
N-nitroso-N-substituted hydroxylamines as nitric oxide donors
|
US5714511A
(en)
*
|
1995-07-31 |
1998-02-03 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Selective prevention of organ injury in sepsis and shock using selection release of nitric oxide in vulnerable organs
|
US6610660B1
(en)
*
|
1996-09-27 |
2003-08-26 |
The United States Of America As Represented By The Department Of Health And Human Services |
O2-arylated or O2-glycosylated 1-substituted diazen-1-ium-1,2-diolates and O2-substituted 1-[(2-carboxylato) pyrrolidin-1-yl] diazen-1-ium-1,2-diolates
|
AU726861B2
(en)
*
|
1997-07-03 |
2000-11-23 |
Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The |
Novel nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
|
US6103275A
(en)
*
|
1998-06-10 |
2000-08-15 |
Nitric Oxide Solutions |
Systems and methods for topical treatment with nitric oxide
|
US20040043068A1
(en)
*
|
1998-09-29 |
2004-03-04 |
Eugene Tedeschi |
Uses for medical devices having a lubricious, nitric oxide-releasing coating
|
US6261594B1
(en)
|
1998-11-25 |
2001-07-17 |
The University Of Akron |
Chitosan-based nitric oxide donor compositions
|
US6270779B1
(en)
*
|
2000-05-10 |
2001-08-07 |
United States Of America |
Nitric oxide-releasing metallic medical devices
|
US6673338B1
(en)
|
2001-09-10 |
2004-01-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Nitric oxide-releasing imidate and thioimidate diazeniumdiolates, compositions, uses thereof and method of making same
|
WO2003026717A1
(en)
*
|
2001-09-26 |
2003-04-03 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Nitric oxide-releasing coated medical devices and method of preparing same
|
US6703046B2
(en)
|
2001-10-04 |
2004-03-09 |
Medtronic Ave Inc. |
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
|
EP1490045B1
(en)
*
|
2002-03-21 |
2013-03-13 |
University of Utah Research Foundation |
In vivo use of glutathionone s-transferase activated nitric oxide donors
|
US20040038947A1
(en)
*
|
2002-06-14 |
2004-02-26 |
The Gov. Of The U.S. Of America As Represented By The Sec. Of The Dept. Of Health & Human Services |
Method of treating ischemia/reperfusion injury with nitroxyl donors
|
US6949530B2
(en)
*
|
2002-07-18 |
2005-09-27 |
The United States Of America As Represented By The Department Of Health And Human Services |
Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same
|
AU2003281815A1
(en)
*
|
2002-08-02 |
2004-02-23 |
The Government Of The United States Of America, Represented By The Secretary, Dept. Of Health And Hu |
Cross-linked nitric oxide-releasing polyamine coated substrates, compositions comprising same and method of making same
|
US6936639B2
(en)
*
|
2002-08-21 |
2005-08-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Nitroxyl progenitors in the treatment of heart failure
|
US20050009789A1
(en)
*
|
2003-05-13 |
2005-01-13 |
The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Service |
Cyclooxygenase inhibition with nitroxyl
|
JP4738352B2
(ja)
*
|
2004-02-09 |
2011-08-03 |
アミュレット ファーマシューティカルズ インコーポレイティッド |
一酸化窒素放出ポリマー
|
US7569559B2
(en)
*
|
2004-02-09 |
2009-08-04 |
Noxilizer, Inc. |
Nitric oxide-releasing molecules
|
FR2872158B1
(fr)
*
|
2004-06-28 |
2006-11-03 |
Merck Sante Soc Par Actions Si |
Nouveaux composes diazeniumdiolates, leur procede de preparation et leur utilisation therapeutique
|
US7968664B2
(en)
|
2004-09-27 |
2011-06-28 |
The United States Of America As Represented By The Department Of Health And Human Services |
Nitric oxide-releasing diazeniumdiolated acrylonitrile-based polymers, and compositions, medical devices, and uses thereof
|
CA2613477C
(en)
*
|
2005-06-23 |
2013-12-03 |
Johns Hopkins University |
Thiol-sensitive positive inotropes
|
US8021679B2
(en)
|
2005-08-25 |
2011-09-20 |
Medtronic Vascular, Inc |
Nitric oxide-releasing biodegradable polymers useful as medical devices and coatings therefore
|
US20070053952A1
(en)
*
|
2005-09-07 |
2007-03-08 |
Medtronic Vascular, Inc. |
Nitric oxide-releasing polymers derived from modified polymers
|
AU2006309212B2
(en)
*
|
2005-10-31 |
2011-09-15 |
Government Of The United States Of America, Represented By The Secretary Department Of Health And Human Services |
Polysaccharide-derived nitric oxide-releasing carbon-bound diazeniumdiolates
|
US20070196327A1
(en)
*
|
2005-12-06 |
2007-08-23 |
Amulet Pharmaceuticals, Inc. |
Nitric oxide releasing polymers
|
US8241619B2
(en)
*
|
2006-05-15 |
2012-08-14 |
Medtronic Vascular, Inc. |
Hindered amine nitric oxide donating polymers for coating medical devices
|
US9259535B2
(en)
|
2006-06-22 |
2016-02-16 |
Excelsior Medical Corporation |
Antiseptic cap equipped syringe
|
US11229746B2
(en)
|
2006-06-22 |
2022-01-25 |
Excelsior Medical Corporation |
Antiseptic cap
|
US7811600B2
(en)
*
|
2007-03-08 |
2010-10-12 |
Medtronic Vascular, Inc. |
Nitric oxide donating medical devices and methods of making same
|
WO2009000089A1
(en)
*
|
2007-06-28 |
2008-12-31 |
University Of Saskatchewan |
Immunomodulatory compositions and methods for treating disease with modified host defense peptides
|
US8273828B2
(en)
|
2007-07-24 |
2012-09-25 |
Medtronic Vascular, Inc. |
Methods for introducing reactive secondary amines pendant to polymers backbones that are useful for diazeniumdiolation
|
US20090222088A1
(en)
*
|
2008-02-29 |
2009-09-03 |
Medtronic Vascular, Inc. |
Secondary Amine Containing Nitric Oxide Releasing Polymer Composition
|
US9005656B2
(en)
*
|
2008-03-07 |
2015-04-14 |
University Of Utah Research Foundation |
Activated nitric oxide donors and methods of making and using thereof
|
US20090232863A1
(en)
*
|
2008-03-17 |
2009-09-17 |
Medtronic Vascular, Inc. |
Biodegradable Carbon Diazeniumdiolate Based Nitric Oxide Donating Polymers
|
US20090232868A1
(en)
*
|
2008-03-17 |
2009-09-17 |
Medtronic Vascular, Inc. |
Nitric Oxide Releasing Polymer Composition
|
US9078992B2
(en)
|
2008-10-27 |
2015-07-14 |
Pursuit Vascular, Inc. |
Medical device for applying antimicrobial to proximal end of catheter
|
US8158187B2
(en)
|
2008-12-19 |
2012-04-17 |
Medtronic Vascular, Inc. |
Dry diazeniumdiolation methods for producing nitric oxide releasing medical devices
|
US8425837B2
(en)
|
2009-02-23 |
2013-04-23 |
Noxilizer, Inc. |
Device and method for gas sterilization
|
US8709465B2
(en)
|
2009-04-13 |
2014-04-29 |
Medtronic Vascular, Inc. |
Diazeniumdiolated phosphorylcholine polymers for nitric oxide release
|
US20110160200A1
(en)
*
|
2009-11-23 |
2011-06-30 |
Cardioxyl Pharmaceuticals, Inc. |
Nitroxyl Progenitors for the Treatment of Pulmonary Hypertension
|
MX356796B
(es)
*
|
2009-12-07 |
2018-06-14 |
Cardioxyl Pharmaceuticals Inc |
Derivados de hidroxilamina bis-acilados.
|
WO2011071951A2
(en)
*
|
2009-12-07 |
2011-06-16 |
Johns Hopkins University |
N-acyloxysulfonamide and n-hydroxy-n-acylsulfonamide derivatives
|
US20110301299A1
(en)
|
2010-06-08 |
2011-12-08 |
Medtronic Vascular, Inc. |
Medical Devices and Polymers Therefor Having PTFE Surfaces Modified With Nitric Oxide-Releasing Polymers
|
US10166381B2
(en)
|
2011-05-23 |
2019-01-01 |
Excelsior Medical Corporation |
Antiseptic cap
|
ES2797649T3
(es)
|
2011-07-12 |
2020-12-03 |
Icu Medical Inc |
Dispositivo para entrega de agente antimicrobiano en un catéter transdérmico
|
WO2015168677A1
(en)
|
2014-05-02 |
2015-11-05 |
Excelsior Medical Corporation |
Strip package for antiseptic cap
|
AU2016262400B2
(en)
|
2015-05-08 |
2021-01-21 |
Icu Medical, Inc. |
Medical connectors configured to receive emitters of therapeutic agents
|
ES2929769T3
(es)
|
2016-10-14 |
2022-12-01 |
Icu Medical Inc |
Tapas desinfectantes para conectores médicos
|
WO2018204206A2
(en)
|
2017-05-01 |
2018-11-08 |
Icu Medical, Inc. |
Medical fluid connectors and methods for providing additives in medical fluid lines
|
US11534595B2
(en)
|
2018-11-07 |
2022-12-27 |
Icu Medical, Inc. |
Device for delivering an antimicrobial composition into an infusion device
|
US11541220B2
(en)
|
2018-11-07 |
2023-01-03 |
Icu Medical, Inc. |
Needleless connector with antimicrobial properties
|
US11400195B2
(en)
|
2018-11-07 |
2022-08-02 |
Icu Medical, Inc. |
Peritoneal dialysis transfer set with antimicrobial properties
|
US11541221B2
(en)
|
2018-11-07 |
2023-01-03 |
Icu Medical, Inc. |
Tubing set with antimicrobial properties
|
US11517732B2
(en)
|
2018-11-07 |
2022-12-06 |
Icu Medical, Inc. |
Syringe with antimicrobial properties
|
EP3883638A1
(en)
|
2018-11-21 |
2021-09-29 |
ICU Medical, Inc. |
Antimicrobial device comprising a cap with ring and insert
|
CA3204371A1
(en)
|
2020-12-07 |
2022-06-16 |
Icu Medical, Inc. |
Peritoneal dialysis caps, systems and methods
|