IT1247093B - Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono - Google Patents

Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Info

Publication number
IT1247093B
IT1247093B ITMI910133A ITMI910133A IT1247093B IT 1247093 B IT1247093 B IT 1247093B IT MI910133 A ITMI910133 A IT MI910133A IT MI910133 A ITMI910133 A IT MI910133A IT 1247093 B IT1247093 B IT 1247093B
Authority
IT
Italy
Prior art keywords
myinositol
procedure
contain
preparation
pharmaceutical compositions
Prior art date
Application number
ITMI910133A
Other languages
English (en)
Inventor
Emanuela Previtali
Original Assignee
Flarer S R L Ora Castellini S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Flarer S R L Ora Castellini S filed Critical Flarer S R L Ora Castellini S
Priority to ITMI910133A priority Critical patent/IT1247093B/it
Publication of ITMI910133A0 publication Critical patent/ITMI910133A0/it
Priority to EP19920200164 priority patent/EP0496474A3/en
Publication of ITMI910133A1 publication Critical patent/ITMI910133A1/it
Application granted granted Critical
Publication of IT1247093B publication Critical patent/IT1247093B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/26—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one amino group bound to the carbon skeleton, e.g. lysine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/117—Esters of phosphoric acids with cycloaliphatic alcohols

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

I derivati salini del gliceril fosforil mioinositolo con basi organiche o composti organici basici farmacologicamente attivi, aventi formula: (FORMULA) sono terapeuticamente utili nel trattamento di sindromi cerebrali connesse alla senescenza.
ITMI910133A 1991-01-22 1991-01-22 Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono IT1247093B (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
ITMI910133A IT1247093B (it) 1991-01-22 1991-01-22 Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
EP19920200164 EP0496474A3 (en) 1991-01-22 1992-01-21 Saline derivates of glyceryl phosphoryl myoinositol having therapeutical activity, their preparation and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910133A IT1247093B (it) 1991-01-22 1991-01-22 Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Publications (3)

Publication Number Publication Date
ITMI910133A0 ITMI910133A0 (it) 1991-01-22
ITMI910133A1 ITMI910133A1 (it) 1992-07-22
IT1247093B true IT1247093B (it) 1994-12-12

Family

ID=11358193

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI910133A IT1247093B (it) 1991-01-22 1991-01-22 Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono

Country Status (2)

Country Link
EP (1) EP0496474A3 (it)
IT (1) IT1247093B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE308548T1 (de) * 2000-11-07 2005-11-15 I R B Istituto Di Ricerche Bio Glycerophosphoinositol-derivate als cytosolic a2 phospholipase modulatoren
JP5670858B2 (ja) * 2011-10-14 2015-02-18 イ．エルレ．ビ．イスティトゥト ディ リチェルケ ビオテクノロジケ ソチエタ ペル アツィオニ サイトゾルのホスホリパーゼのモジュレーターとしてのグリセロホスホイノシトール誘導体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1239474B (it) * 1989-10-27 1993-11-02 Depha Team Srl Composizioni farmaceutiche a base di l-alfa-glicerofosforil-d-myo- inositolo o suoi sali alcalini o alcalino-terrosi per la terapia delleneuropatie periferiche di origine dismetabolica o tossica, e delle cerebropatie su base organica e funzionale

Also Published As

Publication number Publication date
EP0496474A3 (en) 1992-12-02
EP0496474A2 (en) 1992-07-29
ITMI910133A1 (it) 1992-07-22
ITMI910133A0 (it) 1991-01-22

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Legal Events

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0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960130