DK176010B1 - Medikament-lipid-systemer med lav toxicitet - Google Patents
Medikament-lipid-systemer med lav toxicitet Download PDFInfo
- Publication number
- DK176010B1 DK176010B1 DK198900980A DK98089A DK176010B1 DK 176010 B1 DK176010 B1 DK 176010B1 DK 198900980 A DK198900980 A DK 198900980A DK 98089 A DK98089 A DK 98089A DK 176010 B1 DK176010 B1 DK 176010B1
- Authority
- DK
- Denmark
- Prior art keywords
- lipid
- drug
- amphotericin
- composition according
- bioactive agent
- Prior art date
Links
- 0 C***C(C)C(**C)*N****S*C Chemical compound C***C(C)C(**C)*N****S*C 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
- A61K47/544—Phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- G—PHYSICS
- G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
- G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
- G03B2227/00—Photographic printing apparatus
- G03B2227/32—Projection printing apparatus, e.g. enlarging apparatus, copying camera
- G03B2227/325—Microcapsule copiers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Vehicle Step Arrangements And Article Storage (AREA)
- Catalysts (AREA)
- Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2215787A | 1987-03-05 | 1987-03-05 | |
US2215787 | 1987-03-05 | ||
US6990887A | 1987-07-06 | 1987-07-06 | |
US6990887 | 1987-07-06 | ||
US7930987A | 1987-07-29 | 1987-07-29 | |
US7930987 | 1987-07-29 | ||
US8800647 | 1988-03-03 | ||
PCT/US1988/000647 WO1988006443A1 (en) | 1987-03-05 | 1988-03-03 | Low toxicity drug-lipid systems |
Publications (3)
Publication Number | Publication Date |
---|---|
DK98089A DK98089A (da) | 1989-03-01 |
DK98089D0 DK98089D0 (da) | 1989-03-01 |
DK176010B1 true DK176010B1 (da) | 2005-11-28 |
Family
ID=27361805
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK198900980A DK176010B1 (da) | 1987-03-05 | 1989-03-01 | Medikament-lipid-systemer med lav toxicitet |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0282405B2 (ko) |
KR (1) | KR970002870B1 (ko) |
CN (1) | CN1044093C (ko) |
AT (1) | ATE118169T1 (ko) |
AU (1) | AU622405B2 (ko) |
CA (1) | CA1338701C (ko) |
DE (1) | DE3852961T3 (ko) |
DK (1) | DK176010B1 (ko) |
ES (1) | ES2070131T5 (ko) |
FI (1) | FI102724B (ko) |
GR (1) | GR3015916T3 (ko) |
HK (1) | HK1007495A1 (ko) |
IE (1) | IE67152B1 (ko) |
IL (1) | IL85607A (ko) |
LU (1) | LU88684I2 (ko) |
NL (1) | NL990004I1 (ko) |
NO (4) | NO179995C (ko) |
NZ (1) | NZ223660A (ko) |
PT (1) | PT86913B (ko) |
WO (1) | WO1988006443A1 (ko) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5178875A (en) * | 1991-01-14 | 1993-01-12 | The Board Of Regents, The University Of Texas System | Liposomal-polyene preliposomal powder and method for its preparation |
US5830498A (en) * | 1987-10-16 | 1998-11-03 | Board Of Regents, The University Of Texas System | Liposomal-polyene preliposomal powder and method for its preparation |
AU598958B2 (en) * | 1987-11-12 | 1990-07-05 | Vestar, Inc. | Improved amphotericin b liposome preparation |
JP2798302B2 (ja) * | 1989-03-31 | 1998-09-17 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | リポソームおよび脂質複合体組成物の調製 |
US5188951A (en) * | 1990-04-17 | 1993-02-23 | The Liposome Company, Inc. | Enzymatic synthesis of soluble phosphatides from phospholipids |
US5556637A (en) * | 1990-08-06 | 1996-09-17 | A. Nattermann & Cie. Gmbh | Water containing liposome system |
DE4108902A1 (de) * | 1990-08-06 | 1992-02-13 | Nattermann A & Cie | Wasserhaltiges liposomensystem |
US5534502A (en) * | 1990-11-06 | 1996-07-09 | Nippon Shinyaku Co. Ltd. | Process for producing fat emulsion |
WO1992007571A1 (fr) * | 1990-11-06 | 1992-05-14 | Nippon Shinyaku Co., Ltd. | Procede de production d'une emulsion grasse |
EP0599977A1 (en) * | 1991-08-14 | 1994-06-08 | SEQUUS PHARMACEUTICALS, INC. (a Delaware Corporation) | Hiv-treatment method with low-toxicity amphotericin b |
DE1118326T1 (de) * | 1993-05-21 | 2002-04-18 | The Liposome Co., Inc. | Reduzierung von durch Liposomen induzierten physiologischen Gegenreaktionen |
US5716526A (en) * | 1994-01-14 | 1998-02-10 | The Liposome Company, Inc. | Method of separating materials from liposomes or lipid complexes |
US5902604A (en) * | 1995-06-06 | 1999-05-11 | Board Of Regents, The University Of Texas System | Submicron liposome suspensions obtained from preliposome lyophilizates |
GB2326337A (en) | 1997-06-20 | 1998-12-23 | Phares Pharma Holland | Homogeneous lipid compositions for drug delivery |
US6165997A (en) * | 1997-11-20 | 2000-12-26 | Statens Serum Institut | Phospholipids having antimicrobial activity with or without the presence of antimicrobials |
BRPI0619565A2 (pt) * | 2005-12-08 | 2011-10-04 | Wyeth Corp | composições lipossÈmicas |
KR101132626B1 (ko) * | 2009-10-12 | 2012-04-02 | 주식회사 녹십자 | 난용성 약물의 전달을 위한 고밀도지단백 나노입자의 제조방법 |
AU2010359346B2 (en) | 2010-08-20 | 2015-01-29 | Dr. Reddy's Laboratories Sa | Phospholipid depot |
BR112013009743A2 (pt) | 2010-10-22 | 2016-07-19 | Reddys Lab Inc Dr | uso de deposito de fosfolipidio viscoso estavel ao armazenamento para tratar ferimentos |
US9668974B2 (en) | 2012-05-10 | 2017-06-06 | Painreform Ltd. | Depot formulations of a local anesthetic and methods for preparation thereof |
US10799456B2 (en) | 2015-06-15 | 2020-10-13 | University Of Washington | Multiple drug lipid nanoparticle composition and related methods for extended drug levels in blood and lymph tissue |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4310506A (en) * | 1979-02-22 | 1982-01-12 | California Institute Of Technology | Means of preparation and applications of liposomes containing high concentrations of entrapped ionic species |
FR2521565B1 (fr) * | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
US4604376A (en) * | 1982-04-21 | 1986-08-05 | Research Corporation | Enteric compounds and complexes |
US4436746A (en) * | 1982-09-30 | 1984-03-13 | Ciba-Geigy Corporation | Thromboxane synthetase inhibitory N-substituted-2-(1-imidazolyl)indoles |
US4622219A (en) * | 1983-06-17 | 1986-11-11 | Haynes Duncan H | Method of inducing local anesthesia using microdroplets of a general anesthetic |
IL78930A0 (en) * | 1985-07-29 | 1986-09-30 | Abbott Lab | Lyophilized emulsion compositions for parenteral administration |
IL78929A0 (en) * | 1985-07-29 | 1986-09-30 | Abbott Lab | Microemulsion compositions for parenteral administration |
-
1988
- 1988-02-26 NZ NZ223660A patent/NZ223660A/en unknown
- 1988-02-29 CA CA000560121A patent/CA1338701C/en not_active Expired - Lifetime
- 1988-03-02 IL IL85607A patent/IL85607A/xx not_active IP Right Cessation
- 1988-03-03 KR KR1019880701402A patent/KR970002870B1/ko not_active IP Right Cessation
- 1988-03-03 AU AU17990/88A patent/AU622405B2/en not_active Expired
- 1988-03-03 WO PCT/US1988/000647 patent/WO1988006443A1/en active IP Right Grant
- 1988-03-03 IE IE60088A patent/IE67152B1/en not_active IP Right Cessation
- 1988-03-04 PT PT86913A patent/PT86913B/pt not_active IP Right Cessation
- 1988-03-04 ES ES88400520T patent/ES2070131T5/es not_active Expired - Lifetime
- 1988-03-04 EP EP88400520A patent/EP0282405B2/en not_active Expired - Lifetime
- 1988-03-04 AT AT88400520T patent/ATE118169T1/de active
- 1988-03-04 DE DE3852961T patent/DE3852961T3/de not_active Expired - Lifetime
- 1988-03-04 LU LU88684C patent/LU88684I2/fr unknown
- 1988-03-05 CN CN88101864A patent/CN1044093C/zh not_active Expired - Lifetime
- 1988-10-04 NO NO884391A patent/NO179995C/no not_active IP Right Cessation
-
1989
- 1989-03-01 DK DK198900980A patent/DK176010B1/da not_active IP Right Cessation
- 1989-09-04 FI FI894161A patent/FI102724B/fi not_active IP Right Cessation
-
1994
- 1994-10-26 NO NO944071A patent/NO180147C/no not_active IP Right Cessation
-
1995
- 1995-04-25 GR GR950401037T patent/GR3015916T3/el unknown
-
1998
- 1998-03-25 NO NO1998012C patent/NO1998012I1/no unknown
- 1998-03-25 NO NO1998013C patent/NO1998013I1/no unknown
- 1998-06-25 HK HK98106740A patent/HK1007495A1/xx not_active IP Right Cessation
-
1999
- 1999-01-26 NL NL990004C patent/NL990004I1/nl unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AGE | Re-establishment of rights: approved | ||
CTFF | Application for supplementary protection certificate (spc) filed |
Spc suppl protection certif: CA 2006 00014 Filing date: 20060524 Expiry date: 20100209 |
|
CTFG | Supplementary protection certificate (spc) issued |
Free format text: PRODUCT NAME: AMPHOTERICIN B, LIPID KOMPLEKS Spc suppl protection certif: CA 2006 00014 Filing date: 20060524 |
|
PUP | Patent expired |