KR890009399A - 순환기용제 - Google Patents

순환기용제 Download PDF

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Publication number
KR890009399A
KR890009399A KR1019880016362A KR880016362A KR890009399A KR 890009399 A KR890009399 A KR 890009399A KR 1019880016362 A KR1019880016362 A KR 1019880016362A KR 880016362 A KR880016362 A KR 880016362A KR 890009399 A KR890009399 A KR 890009399A
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KR
South Korea
Prior art keywords
acid addition
physiologically acceptable
acceptable acid
addition salt
substituted
Prior art date
Application number
KR1019880016362A
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English (en)
Other versions
KR960009417B1 (ko
Inventor
요시아키 요시쿠니
노부토시 고지마
모리카즈야
Original Assignee
아만 히데아키
닛본 신야쿠 가부시기가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 아만 히데아키, 닛본 신야쿠 가부시기가이샤 filed Critical 아만 히데아키
Publication of KR890009399A publication Critical patent/KR890009399A/ko
Application granted granted Critical
Publication of KR960009417B1 publication Critical patent/KR960009417B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

내용 없음

Description

순환기용제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. ① 하기 일반식(I)로 표시되는 화합물, 그 생리학적 허용 산부가염, 및 그4급염, ② 노지리마이신 및 그 생리학적 허용 산부가염, ③ 1,4-비스(3-모라놀리노-1-프로페닐)벤젠 및 그 생리학적 허용 산부가염, ④카스타노스페르민의 상기 ①-④로 구성된 군으로부터 선택되는 화합물을 주성분으로하는 2-플라스민 인히비터자하제.
    상기식에서, R1은 수소, 알킬, 카르복시알킬, 알킬옥시카르보닐알킬, 히드록시알킬, 시클로알킬알킬, 아릴알킬, 아릴옥시알킬, 알케닐, 또는 치환이나 무치환의 아릴알케닐을 나타낸다.
  2. ① 하기 일반식(Ⅱ)로 표시되는 화합물, 그 생리학적 허용 산부가염, 및 그 4급염, ② 노지리마이신 및 그 생리학적 허용 산부가염. ③ 1,4-비스(3-모라놀리노-1-프로페닐)벤젠 및 그 생리학적 허용 산부가염, ④카스타노스페르민의 상기 ①-④로 구성된 군으로부터 선택되는 화합물을 주성분으로하는 우로키나제분비촉진제.
    상기식에서, R2는 수소, 알킬, 카르복시알킬, 알킬옥시 카르보닐알킬, 히드록시알킬, 시클로알킬알킬, 치환 또는 무치환의 아릴알케닐, 아릴옥시알케닐 또는 알킬카르바모일알킬을 나타낸다.
  3. ①하기 일반식(Ⅱ)로 표시되는 화합물, 그 생리학적 허용 산부가염. 및 그 4급염, ② 노지리마이신 및 그 생리학적 허용 산부가염. ③ 1,4-비스(3-모라놀리노-1-프로페닐)벤젠 및 그 생리학적 허용 산부가염, ④카스타노스페르민의 상기 ①-④로 구성된 군으로부터 선택되는 화합물을 주성분으로하는 혈전용해제.
    상기식에서, R2는 수소, 알킬, 카르복시알킬, 알킬옥시 카르보닐알킬, 히드록시알킬, 시클로알킬알킬, 치환 또는 무치환의 아릴알킬, 치환 또는 무치환의 아릴옥시알킬, 알케닐, 히드록시알케닐, 치환 또는 무치환의 아릴알케닐, 아릴옥시알케닐 또는 알킬 카르바모일 알킬을 나타낸다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880016362A 1987-12-09 1988-12-09 순환기용제 KR960009417B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP31134887 1987-12-09
JP87-311348 1987-12-09
JP?62-311348 1987-12-09

Publications (2)

Publication Number Publication Date
KR890009399A true KR890009399A (ko) 1989-08-01
KR960009417B1 KR960009417B1 (ko) 1996-07-19

Family

ID=18016066

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880016362A KR960009417B1 (ko) 1987-12-09 1988-12-09 순환기용제

Country Status (11)

Country Link
EP (1) EP0319986B1 (ko)
KR (1) KR960009417B1 (ko)
AT (1) ATE149836T1 (ko)
BE (1) BE1004874A4 (ko)
CA (1) CA1316831C (ko)
CH (1) CH677610A5 (ko)
DE (1) DE3855824T2 (ko)
FR (1) FR2626470B1 (ko)
GB (2) GB8827701D0 (ko)
IL (1) IL88573A (ko)
SE (1) SE502110C2 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0430983B1 (en) * 1988-08-10 1994-04-20 The Australian National University Use of castanospermine as an anti-inflammatory and immunosuppressant agent
WO1998006264A1 (en) * 1996-08-14 1998-02-19 Myung Hee Chun Plasmin-depletion therapy
EP1903034A1 (en) * 2006-09-19 2008-03-26 Technische Universität Graz Iminosugar glycoconjugates

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54106477A (en) * 1978-02-03 1979-08-21 Nippon Shinyaku Co Ltd Moranoline derivative
JPS5943946B2 (ja) * 1978-04-28 1984-10-25 日本新薬株式会社 Ｎ−アルケニルモラノリン誘導体
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
JPS5943947B2 (ja) * 1978-05-03 1984-10-25 日本新薬株式会社 Ｎ−置換モラノリン誘導体
JPS6026387B2 (ja) * 1979-01-20 1985-06-24 日本新薬株式会社 シンナミルモラノリン誘導体
JPS5943949B2 (ja) * 1978-09-29 1984-10-25 日本新薬株式会社 モラノリンのｎ−置換誘導体
DE2925943A1 (de) * 1979-06-27 1981-01-29 Bayer Ag 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
JPS56108767A (en) * 1980-01-28 1981-08-28 Nippon Shinyaku Co Ltd Bismoranoline derivative
DE3007078A1 (de) * 1980-02-26 1981-09-10 Bayer Ag, 5090 Leverkusen Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung
JPS60224675A (ja) * 1984-04-24 1985-11-09 Meiji Seika Kaisha Ltd 新規１−デオキシノジリマイシン誘導体およびそれを含有する血中脂質低下剤
CA1327970C (en) * 1985-05-24 1994-03-22 Paul S. Liu Isolation of castanospermine and its use as an antidiabetic agent
DE3650377T2 (de) * 1985-12-23 1996-02-22 Hutchinson Fred Cancer Res Regulierung der retroviralen replikation, infektion und pathogenese.
ZA883925B (en) * 1987-06-08 1989-02-22 Merrell Dow Pharma Inhibitors of glycoprotein processing having anti-retroviral activity

Also Published As

Publication number Publication date
GB8827927D0 (en) 1989-01-05
KR960009417B1 (ko) 1996-07-19
FR2626470A1 (fr) 1989-08-04
SE8804436D0 (sv) 1988-12-08
GB2213374B (en) 1992-01-29
FR2626470B1 (fr) 1994-12-09
GB8827701D0 (en) 1988-12-29
IL88573A (en) 1994-05-30
ATE149836T1 (de) 1997-03-15
CA1316831C (en) 1993-04-27
EP0319986A3 (en) 1992-09-30
CH677610A5 (ko) 1991-06-14
EP0319986A2 (en) 1989-06-14
EP0319986B1 (en) 1997-03-12
DE3855824D1 (de) 1997-04-17
SE502110C2 (sv) 1995-08-21
DE3855824T2 (de) 1997-10-16
SE8804436L (sv) 1989-06-10
GB2213374A (en) 1989-08-16
BE1004874A4 (fr) 1993-02-16

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