KR890006640A - 항불안성인 r-n-(1-아자비시클로[2.2.2]옥트-3-일)벤즈아미드 및 티오벤즈아미드 - Google Patents

항불안성인 r-n-(1-아자비시클로[2.2.2]옥트-3-일)벤즈아미드 및 티오벤즈아미드 Download PDF

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Publication number
KR890006640A
KR890006640A KR1019880013522A KR880013522A KR890006640A KR 890006640 A KR890006640 A KR 890006640A KR 1019880013522 A KR1019880013522 A KR 1019880013522A KR 880013522 A KR880013522 A KR 880013522A KR 890006640 A KR890006640 A KR 890006640A
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KR
South Korea
Prior art keywords
formula
compound
alkyl
amino
carbon atoms
Prior art date
Application number
KR1019880013522A
Other languages
English (en)
Korean (ko)
Inventor
르노드 아랑
랑글로아 미셸
존 네일러 로버트
네일러 브렌다
Original Assignee
원본미기재
드라랑드 소시에떼 아노님
에이.에이취.로빈스 컴퍼니, 인코오퍼레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 원본미기재, 드라랑드 소시에떼 아노님, 에이.에이취.로빈스 컴퍼니, 인코오퍼레이티드 filed Critical 원본미기재
Publication of KR890006640A publication Critical patent/KR890006640A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019880013522A 1987-10-16 1988-10-17 항불안성인 r-n-(1-아자비시클로[2.2.2]옥트-3-일)벤즈아미드 및 티오벤즈아미드 KR890006640A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP87402321A EP0311724A1 (en) 1987-10-16 1987-10-16 Anxiolytic-R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides
EP87402321.1 1987-10-16

Publications (1)

Publication Number Publication Date
KR890006640A true KR890006640A (ko) 1989-06-15

Family

ID=8198265

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880013522A KR890006640A (ko) 1987-10-16 1988-10-17 항불안성인 r-n-(1-아자비시클로[2.2.2]옥트-3-일)벤즈아미드 및 티오벤즈아미드

Country Status (11)

Country Link
EP (1) EP0311724A1 (da)
JP (1) JPH01199969A (da)
KR (1) KR890006640A (da)
AU (1) AU618027B2 (da)
CA (1) CA1322552C (da)
DK (1) DK576188A (da)
IL (1) IL87992A0 (da)
NZ (1) NZ226581A (da)
PH (1) PH25858A (da)
PT (1) PT88759B (da)
ZA (1) ZA887601B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
WO1991007402A1 (en) * 1989-11-17 1991-05-30 Pfizer Inc. Azabicyclo amides and esters as 5-ht3 receptor antagonists
US5446050A (en) * 1989-11-17 1995-08-29 Pfizer Inc. Azabicyclo amides and esters as 5-HT3 receptor antagonists
US5192770A (en) * 1990-12-07 1993-03-09 Syntex (U.S.A.) Inc. Serotonergic alpha-oxoacetamides
ZA92278B (en) * 1991-02-01 1992-10-28 Akzo Nv 3-quinuclidine derivatives
GB0310867D0 (en) 2003-05-12 2003-06-18 Novartis Ag Organic compounds
CN103619354A (zh) 2011-06-30 2014-03-05 东丽株式会社 止痒剂

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7611713A (nl) * 1975-11-03 1977-05-05 Thomae Gmbh Dr K Werkwijze voor de bereiding van verbindingen en preparaten met waardevolle farmacologische eigen- schappen.
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS5967284A (ja) * 1982-07-13 1984-04-16 サンド・アクチエンゲルシヤフト インドリルカルボン酸ピペリジルエステル誘導体
US4593034A (en) * 1984-04-06 1986-06-03 A. H. Robins Company, Inc. 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides
US4605652A (en) * 1985-02-04 1986-08-12 A. H. Robins Company, Inc. Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
US4870181A (en) * 1985-02-04 1989-09-26 A. H. Robins Company, Incorporated Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides
US4722834A (en) * 1986-03-05 1988-02-02 A. H. Robins Company, Incorporated Method of using 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamide-N-oxides to control emesis caused by anticancer drugs
DE3780276T2 (de) * 1986-12-16 1993-02-25 Robins Co Inc A H Angstloesende n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide und -thiobenzamide.
FR2610323B1 (fr) * 1987-02-04 1989-06-23 Delalande Sa Enantiomeres de configuration absolue s de derives amide de l'amino-3 quinuclidine, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
JPH01199969A (ja) 1989-08-11
CA1322552C (en) 1993-09-28
DK576188A (da) 1989-04-17
AU618027B2 (en) 1991-12-12
DK576188D0 (da) 1988-10-14
IL87992A0 (en) 1989-06-30
ZA887601B (en) 1989-07-26
EP0311724A1 (en) 1989-04-19
PH25858A (en) 1991-12-02
NZ226581A (en) 1991-04-26
AU2374988A (en) 1989-04-20
PT88759B (pt) 1992-12-31

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