KR890000380B1 - 벤조 헤테로사이클 화합물의 제조방법 - Google Patents

벤조 헤테로사이클 화합물의 제조방법 Download PDF

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Publication number
KR890000380B1
KR890000380B1 KR8203945A KR820003945A KR890000380B1 KR 890000380 B1 KR890000380 B1 KR 890000380B1 KR 8203945 A KR8203945 A KR 8203945A KR 820003945 A KR820003945 A KR 820003945A KR 890000380 B1 KR890000380 B1 KR 890000380B1
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KR
South Korea
Prior art keywords
compound
formula
acid addition
group
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR8203945A
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English (en)
Korean (ko)
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KR840001560A (ko
Inventor
쉬롬 쿠르트
멘트루프 안톤
렌스 에른스트-오토
퓌크너 아르민
Original Assignee
페터 베에르호프, 기셀라 베흘만
베링거 인겔하임 케이지
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 페터 베에르호프, 기셀라 베흘만, 베링거 인겔하임 케이지 filed Critical 페터 베에르호프, 기셀라 베흘만
Publication of KR840001560A publication Critical patent/KR840001560A/ko
Application granted granted Critical
Publication of KR890000380B1 publication Critical patent/KR890000380B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR8203945A 1981-09-01 1982-09-01 벤조 헤테로사이클 화합물의 제조방법 Expired KR890000380B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3134590.5 1981-09-01
DE19813134590 DE3134590A1 (de) 1981-09-01 1981-09-01 Neue benzo-heterocyclen

Publications (2)

Publication Number Publication Date
KR840001560A KR840001560A (ko) 1984-05-07
KR890000380B1 true KR890000380B1 (ko) 1989-03-15

Family

ID=6140603

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8203945A Expired KR890000380B1 (ko) 1981-09-01 1982-09-01 벤조 헤테로사이클 화합물의 제조방법

Country Status (25)

Country Link
EP (1) EP0073505B1 (enExample)
JP (1) JPS5852278A (enExample)
KR (1) KR890000380B1 (enExample)
AR (2) AR231976A1 (enExample)
AT (1) ATE16703T1 (enExample)
AU (1) AU553589B2 (enExample)
CA (1) CA1180012A (enExample)
CS (1) CS236679B2 (enExample)
DD (1) DD204477A5 (enExample)
DE (2) DE3134590A1 (enExample)
DK (1) DK158664C (enExample)
ES (3) ES515380A0 (enExample)
FI (1) FI78475C (enExample)
GB (1) GB2106105B (enExample)
GR (1) GR77275B (enExample)
HU (1) HU186112B (enExample)
IE (1) IE53615B1 (enExample)
IL (1) IL66683A0 (enExample)
NO (1) NO157738C (enExample)
NZ (1) NZ201777A (enExample)
PL (1) PL139375B1 (enExample)
PT (1) PT75478A (enExample)
SU (1) SU1149876A3 (enExample)
YU (1) YU42794B (enExample)
ZA (1) ZA826349B (enExample)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4554284A (en) * 1984-09-12 1985-11-19 Smithkline Beckman Corporation 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones
DE3743265A1 (de) * 1987-12-19 1989-06-29 Boehringer Ingelheim Kg Neue ammoniumverbindungen, ihre herstellung und verwendung
TW372967B (en) * 1994-12-27 1999-11-01 Kanebo Ltd 1,4 benzoxazine derivative, pharmaceutical composition containing the same and use thereof
USD474664S1 (en) 2002-04-30 2003-05-20 Trudeau Corporation 1889 Inc. Corkscrew
DE10253282A1 (de) 2002-11-15 2004-05-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
GB0307856D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Organic compounds
JP4516064B2 (ja) * 2003-04-04 2010-08-04 ノバルティス アーゲー 気道疾患の処置のためのキノリン−２−オン誘導体
US7307076B2 (en) 2004-05-13 2007-12-11 Boehringer Ingelheim International Gmbh Beta agonists for the treatment of respiratory diseases
WO2005110990A1 (de) * 2004-05-13 2005-11-24 Boehringer Ingelheim International Gmbh Hydroxy-substituierte benzkondensierte heterozyklen als betaagonisten zur behandlung von atemwegserkrankungen
US7745621B2 (en) 2004-05-14 2010-06-29 Boehringer Ingelheim International Gmbh Long acting bronchodilators for the treatment of respiratory diseases
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004024451A1 (de) * 2004-05-14 2005-12-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten
DE102004024452A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation von Betaagonisten
DE102004024453A1 (de) * 2004-05-14 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen
ES2530991T3 (es) * 2005-08-15 2015-03-09 Boehringer Ingelheim Int Procedimiento para la obtención de betamiméticos
TWI389692B (zh) * 2005-10-10 2013-03-21 Boehringer Ingelheim Int 用以吸入β-共效劑的氣溶膠調配物
GB0602778D0 (en) 2006-02-10 2006-03-22 Glaxo Group Ltd Novel compound
WO2008017638A1 (de) * 2006-08-07 2008-02-14 Boehringer Ingelheim International Gmbh Enantiomerenreine betaagonisten, verfahren zu deren herstellung und deren verwendung als arzneimittel
UY30543A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de beta- agonistas
AR065017A1 (es) * 2007-01-25 2009-05-13 Boehringer Ingelheim Int Procedimiento para la preparacion de betamimeticos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035749A1 (enExample) * 1969-02-06 1970-12-24 Bellon Labor Sa Roger
DE2429253A1 (de) * 1974-06-19 1976-01-15 Boehringer Sohn Ingelheim Phenylalkanolamine

Also Published As

Publication number Publication date
PL238077A1 (en) 1984-04-09
GR77275B (enExample) 1984-09-11
EP0073505B1 (de) 1985-11-27
ES8308318A1 (es) 1983-08-16
GB2106105A (en) 1983-04-07
AU553589B2 (en) 1986-07-24
IE822105L (en) 1983-03-01
DD204477A5 (de) 1983-11-30
IE53615B1 (en) 1988-12-21
CA1180012A (en) 1984-12-27
SU1149876A3 (en) 1985-04-07
GB2106105B (en) 1985-07-10
DK158664C (da) 1991-01-14
NO157738C (no) 1988-05-11
NO822932L (no) 1983-03-02
YU194982A (en) 1984-12-31
FI78475C (fi) 1989-08-10
JPS5852278A (ja) 1983-03-28
ES521871A0 (es) 1984-06-16
IL66683A0 (en) 1982-12-31
ES521870A0 (es) 1984-01-16
CS236679B2 (en) 1985-05-15
DK158664B (da) 1990-07-02
PL139375B1 (en) 1987-01-31
FI822985L (fi) 1983-03-02
NO157738B (no) 1988-02-01
ES8405778A1 (es) 1984-06-16
ZA826349B (en) 1984-04-25
AU8787482A (en) 1983-03-10
HU186112B (en) 1985-06-28
ES8402279A1 (es) 1984-01-16
DK389082A (da) 1983-03-02
ES515380A0 (es) 1983-08-16
NZ201777A (en) 1985-08-30
DE3134590A1 (de) 1983-03-10
ATE16703T1 (de) 1985-12-15
DE3267702D1 (en) 1986-01-09
FI822985A0 (fi) 1982-08-30
JPH035392B2 (enExample) 1991-01-25
FI78475B (fi) 1989-04-28
AR231976A1 (es) 1985-04-30
AR231977A1 (es) 1985-04-30
KR840001560A (ko) 1984-05-07
YU42794B (en) 1988-12-31
PT75478A (en) 1982-09-01
EP0073505A1 (de) 1983-03-09

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