ES8308318A1 - "procedimiento para la preparacion de nuevos benzo-heterociclos". - Google Patents
"procedimiento para la preparacion de nuevos benzo-heterociclos".Info
- Publication number
- ES8308318A1 ES8308318A1 ES515380A ES515380A ES8308318A1 ES 8308318 A1 ES8308318 A1 ES 8308318A1 ES 515380 A ES515380 A ES 515380A ES 515380 A ES515380 A ES 515380A ES 8308318 A1 ES8308318 A1 ES 8308318A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- image
- methyl
- represents hydrogen
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Feed For Specific Animals (AREA)
- Fodder In General (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE BENZO-HETEROCICLOS, DE SUS RACEMATOS, ENANTIOMEROS Y ANTIPODAS DIASTEREOISOMEROS, Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE A, R<1, R<2 Y R<3 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE REDUCCION DE UN COMPUESTO DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y LOS POSIBLES GRUPOS HIDROXILO ESTAN PROTEGIDOS. LA REDUCCION SE LLEVA A CABO POR HIDROGENACION CATALITICA, EN PRESENCIA DE PALADIO, PLATINO O NIQUEL RANEY, O MEDIANTE BOROHIDRURO SODICO O DIBORANO, EN UN DISOLVENTE INERTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SUS EFECTOS BRONCOLITICOS, ESPASMOLITICOS Y ANTIALERGICOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813134590 DE3134590A1 (de) | 1981-09-01 | 1981-09-01 | Neue benzo-heterocyclen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES515380A0 ES515380A0 (es) | 1983-08-16 |
| ES8308318A1 true ES8308318A1 (es) | 1983-08-16 |
Family
ID=6140603
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515380A Expired ES8308318A1 (es) | 1981-09-01 | 1982-08-31 | "procedimiento para la preparacion de nuevos benzo-heterociclos". |
| ES521871A Granted ES521871A0 (es) | 1981-09-01 | 1983-04-27 | Procedimiento para la preparacion de nuevos benzo-heterociclos. |
| ES521870A Granted ES521870A0 (es) | 1981-09-01 | 1983-04-27 | Procedimiento para la preparacion de nuevos benzo-heterociclos. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521871A Granted ES521871A0 (es) | 1981-09-01 | 1983-04-27 | Procedimiento para la preparacion de nuevos benzo-heterociclos. |
| ES521870A Granted ES521870A0 (es) | 1981-09-01 | 1983-04-27 | Procedimiento para la preparacion de nuevos benzo-heterociclos. |
Country Status (25)
| Country | Link |
|---|---|
| EP (1) | EP0073505B1 (es) |
| JP (1) | JPS5852278A (es) |
| KR (1) | KR890000380B1 (es) |
| AR (2) | AR231976A1 (es) |
| AT (1) | ATE16703T1 (es) |
| AU (1) | AU553589B2 (es) |
| CA (1) | CA1180012A (es) |
| CS (1) | CS236679B2 (es) |
| DD (1) | DD204477A5 (es) |
| DE (2) | DE3134590A1 (es) |
| DK (1) | DK158664C (es) |
| ES (3) | ES8308318A1 (es) |
| FI (1) | FI78475C (es) |
| GB (1) | GB2106105B (es) |
| GR (1) | GR77275B (es) |
| HU (1) | HU186112B (es) |
| IE (1) | IE53615B1 (es) |
| IL (1) | IL66683A0 (es) |
| NO (1) | NO157738C (es) |
| NZ (1) | NZ201777A (es) |
| PL (1) | PL139375B1 (es) |
| PT (1) | PT75478A (es) |
| SU (1) | SU1149876A3 (es) |
| YU (1) | YU42794B (es) |
| ZA (1) | ZA826349B (es) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4554284A (en) * | 1984-09-12 | 1985-11-19 | Smithkline Beckman Corporation | 7-(2-Aminoethyl)-1,3-benzthia- or oxa-zol-2(3H)-ones |
| DE3743265A1 (de) * | 1987-12-19 | 1989-06-29 | Boehringer Ingelheim Kg | Neue ammoniumverbindungen, ihre herstellung und verwendung |
| TW372967B (en) * | 1994-12-27 | 1999-11-01 | Kanebo Ltd | 1,4 benzoxazine derivative, pharmaceutical composition containing the same and use thereof |
| US7056916B2 (en) | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| DE10253282A1 (de) | 2002-11-15 | 2004-05-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung |
| PE20040950A1 (es) | 2003-02-14 | 2005-01-01 | Theravance Inc | DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS |
| GB0307856D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Organic compounds |
| JP4516064B2 (ja) * | 2003-04-04 | 2010-08-04 | ノバルティス アーゲー | 気道疾患の処置のためのキノリン−２−オン誘導体 |
| WO2005110990A1 (de) * | 2004-05-13 | 2005-11-24 | Boehringer Ingelheim International Gmbh | Hydroxy-substituierte benzkondensierte heterozyklen als betaagonisten zur behandlung von atemwegserkrankungen |
| US7307076B2 (en) | 2004-05-13 | 2007-12-11 | Boehringer Ingelheim International Gmbh | Beta agonists for the treatment of respiratory diseases |
| US7745621B2 (en) | 2004-05-14 | 2010-06-29 | Boehringer Ingelheim International Gmbh | Long acting bronchodilators for the treatment of respiratory diseases |
| DE102004024452A1 (de) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation von Betaagonisten |
| DE102004024451A1 (de) | 2004-05-14 | 2005-12-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten |
| DE102004024454A1 (de) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| US7220742B2 (en) | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
| DE102004024453A1 (de) * | 2004-05-14 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen |
| MX2008001976A (es) | 2005-08-15 | 2008-03-25 | Boehringer Ingelheim Int | Procedimiento para la preparacion de betamimeticos. |
| TWI389692B (zh) | 2005-10-10 | 2013-03-21 | Boehringer Ingelheim Int | 用以吸入β-共效劑的氣溶膠調配物 |
| GB0602778D0 (en) | 2006-02-10 | 2006-03-22 | Glaxo Group Ltd | Novel compound |
| WO2008017638A1 (de) * | 2006-08-07 | 2008-02-14 | Boehringer Ingelheim International Gmbh | Enantiomerenreine betaagonisten, verfahren zu deren herstellung und deren verwendung als arzneimittel |
| UY30543A1 (es) * | 2006-08-18 | 2008-03-31 | Boehringer Ingelheim Int | Formulacion de aerosol para la inhalacion de beta- agonistas |
| MX2009005813A (es) * | 2007-01-25 | 2009-06-16 | Boehringer Ingelheim Int | Procedimiento para la preparacion de betamimeticos. |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2035749A1 (es) * | 1969-02-06 | 1970-12-24 | Bellon Labor Sa Roger | |
| CA1041523A (en) * | 1974-06-19 | 1978-10-31 | Queen's University | Preparation of 1-oxapenicillins and novel intermediates therefor |
-
1981
- 1981-09-01 DE DE19813134590 patent/DE3134590A1/de not_active Withdrawn
-
1982
- 1982-08-27 SU SU823483451A patent/SU1149876A3/ru active
- 1982-08-28 EP EP82107919A patent/EP0073505B1/de not_active Expired
- 1982-08-28 DE DE8282107919T patent/DE3267702D1/de not_active Expired
- 1982-08-28 AT AT82107919T patent/ATE16703T1/de not_active IP Right Cessation
- 1982-08-30 PL PL1982238077A patent/PL139375B1/pl unknown
- 1982-08-30 DD DD82242881A patent/DD204477A5/de unknown
- 1982-08-30 AR AR290473A patent/AR231976A1/es active
- 1982-08-30 PT PT75478A patent/PT75478A/pt not_active IP Right Cessation
- 1982-08-30 FI FI822985A patent/FI78475C/fi not_active IP Right Cessation
- 1982-08-30 YU YU1949/82A patent/YU42794B/xx unknown
- 1982-08-31 ZA ZA826349A patent/ZA826349B/xx unknown
- 1982-08-31 GR GR69166A patent/GR77275B/el unknown
- 1982-08-31 GB GB08224810A patent/GB2106105B/en not_active Expired
- 1982-08-31 CS CS826329A patent/CS236679B2/cs unknown
- 1982-08-31 HU HU822793A patent/HU186112B/hu not_active IP Right Cessation
- 1982-08-31 JP JP57151626A patent/JPS5852278A/ja active Granted
- 1982-08-31 ES ES515380A patent/ES8308318A1/es not_active Expired
- 1982-08-31 IL IL66683A patent/IL66683A0/xx not_active IP Right Cessation
- 1982-08-31 CA CA000410462A patent/CA1180012A/en not_active Expired
- 1982-08-31 NO NO822932A patent/NO157738C/no unknown
- 1982-08-31 IE IE2105/82A patent/IE53615B1/en not_active IP Right Cessation
- 1982-08-31 NZ NZ201777A patent/NZ201777A/en unknown
- 1982-08-31 AU AU87874/82A patent/AU553589B2/en not_active Ceased
- 1982-08-31 DK DK389082A patent/DK158664C/da not_active IP Right Cessation
- 1982-09-01 KR KR8203945A patent/KR890000380B1/ko active
-
1983
- 1983-04-27 ES ES521871A patent/ES521871A0/es active Granted
- 1983-04-27 ES ES521870A patent/ES521870A0/es active Granted
- 1983-11-17 AR AR294856A patent/AR231977A1/es active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970203 |