ES8802052A1 - Un metodo para preparar derivados de 9-bencilpurina - Google Patents
Un metodo para preparar derivados de 9-bencilpurinaInfo
- Publication number
- ES8802052A1 ES8802052A1 ES550467A ES550467A ES8802052A1 ES 8802052 A1 ES8802052 A1 ES 8802052A1 ES 550467 A ES550467 A ES 550467A ES 550467 A ES550467 A ES 550467A ES 8802052 A1 ES8802052 A1 ES 8802052A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- hydrogen
- ethyl
- methyl
- iii
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 9-BENCILUREA, DE FORMULA (I) Y DE SUS SALES DE ADICION DE ACIDO. CONSISTE EN LA REACCION DE REDUCCION DE UN COMPUESTO DE FORMULA (II) PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE R7 ES HIDROGENO O FLUOR, Y X1, X2, R5 Y R6 PUEDEN SER VARIOS TIPOS DE RADICALES. LA REDUCCION SE LLEVA A CABO POR HIDROGENACION CATALITICA EN UN DISOLVENTE TAL COMO UNALCANOL, O POR TRATAMIENTO CON NIQUEL RANEY EN DISOLUCION ALCANOLICA A UNA TEMPERATURA COMPRENDIDA ENTRE 50JC Y 100JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848408615A GB8408615D0 (en) | 1984-04-04 | 1984-04-04 | Heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8802052A1 true ES8802052A1 (es) | 1987-03-01 |
| ES550467A0 ES550467A0 (es) | 1987-03-01 |
Family
ID=10559131
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541948A Expired ES8606348A1 (es) | 1984-04-04 | 1985-04-03 | Un metodo para preparar un derivado de 9-bencilpurina |
| ES550466A Expired ES8802051A1 (es) | 1984-04-04 | 1985-12-27 | Un metodo para preparar derivados de 9-bencilpurina |
| ES550467A Expired ES8802052A1 (es) | 1984-04-04 | 1985-12-27 | Un metodo para preparar derivados de 9-bencilpurina |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES541948A Expired ES8606348A1 (es) | 1984-04-04 | 1985-04-03 | Un metodo para preparar un derivado de 9-bencilpurina |
| ES550466A Expired ES8802051A1 (es) | 1984-04-04 | 1985-12-27 | Un metodo para preparar derivados de 9-bencilpurina |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0157637A3 (es) |
| JP (1) | JPS60226880A (es) |
| AU (1) | AU4081185A (es) |
| DD (1) | DD233843A5 (es) |
| DK (1) | DK147285A (es) |
| ES (3) | ES8606348A1 (es) |
| FI (1) | FI851351L (es) |
| GB (1) | GB8408615D0 (es) |
| GR (1) | GR850838B (es) |
| HU (1) | HUT37429A (es) |
| IL (1) | IL74803A0 (es) |
| PL (1) | PL252743A1 (es) |
| ZA (1) | ZA852534B (es) |
| ZW (1) | ZW6785A1 (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5204353A (en) * | 1987-04-07 | 1993-04-20 | Ciba-Geigy Corporation | 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith |
| EP0363320A3 (de) * | 1988-10-06 | 1991-11-21 | Ciba-Geigy Ag | Substituierte 9H-Purine |
| US5166209A (en) * | 1989-04-21 | 1992-11-24 | Burroughs Wellcome Co. | Pharmacologically active compounds |
| GB8913011D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Anticonvulsant pyrazines |
| US5240937A (en) * | 1990-04-20 | 1993-08-31 | Burroughs Wellcome Co. | Pharmaceutically active triazolopyridine compounds |
| DK0778277T3 (da) * | 1995-12-08 | 2003-10-27 | Pfizer | Substituerede heterocycliske derivater som CRF antagonister |
| US6992188B1 (en) | 1995-12-08 | 2006-01-31 | Pfizer, Inc. | Substituted heterocyclic derivatives |
| US6107300A (en) * | 1996-03-27 | 2000-08-22 | Dupont Pharmaceuticals | Arylamino fused pyrimidines |
| US6648453B2 (en) | 1997-07-15 | 2003-11-18 | Silverbrook Research Pty Ltd | Ink jet printhead chip with predetermined micro-electromechanical systems height |
| WO2022011171A1 (en) * | 2020-07-08 | 2022-01-13 | Klotho Therapeutics, Inc. | Novel compounds and methods for increasing klotho gene expression |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3846426A (en) * | 1971-03-03 | 1974-11-05 | Int Minerals & Chem Corp | 6-amino-9-(substituted benzyl) purines and their n{11 oxides |
| US3862189A (en) * | 1973-08-14 | 1975-01-21 | Warner Lambert Co | Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents |
| GB1547214A (en) * | 1977-08-09 | 1979-06-06 | Merck & Co Inc | Purine derivatives |
| US4189485A (en) * | 1977-08-23 | 1980-02-19 | Takeda Chemical Industries, Ltd. | Purine derivatives |
| US4900826A (en) * | 1981-09-24 | 1990-02-13 | Kohjin Co., Ltd. | Process for preparing N6,9-disubstituted adenine |
-
1984
- 1984-04-04 GB GB848408615A patent/GB8408615D0/en active Pending
-
1985
- 1985-04-01 DK DK147285A patent/DK147285A/da not_active IP Right Cessation
- 1985-04-02 EP EP85302321A patent/EP0157637A3/en not_active Withdrawn
- 1985-04-03 ES ES541948A patent/ES8606348A1/es not_active Expired
- 1985-04-03 GR GR850838A patent/GR850838B/el unknown
- 1985-04-03 ZA ZA852534A patent/ZA852534B/xx unknown
- 1985-04-03 PL PL25274385A patent/PL252743A1/xx unknown
- 1985-04-03 IL IL74803A patent/IL74803A0/xx unknown
- 1985-04-03 HU HU851270A patent/HUT37429A/hu unknown
- 1985-04-03 AU AU40811/85A patent/AU4081185A/en not_active Abandoned
- 1985-04-03 DD DD85274834A patent/DD233843A5/de unknown
- 1985-04-03 ZW ZW67/85A patent/ZW6785A1/xx unknown
- 1985-04-03 JP JP60070739A patent/JPS60226880A/ja active Pending
- 1985-04-03 FI FI851351A patent/FI851351L/fi not_active Application Discontinuation
- 1985-12-27 ES ES550466A patent/ES8802051A1/es not_active Expired
- 1985-12-27 ES ES550467A patent/ES8802052A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GR850838B (es) | 1985-11-25 |
| EP0157637A2 (en) | 1985-10-09 |
| EP0157637A3 (en) | 1986-11-05 |
| IL74803A0 (en) | 1985-07-31 |
| HUT37429A (en) | 1985-12-28 |
| ES541948A0 (es) | 1986-04-16 |
| ES8802051A1 (es) | 1987-03-01 |
| GB8408615D0 (en) | 1984-05-16 |
| DK147285D0 (da) | 1985-04-01 |
| ES8606348A1 (es) | 1986-04-16 |
| FI851351L (fi) | 1985-10-05 |
| DD233843A5 (de) | 1986-03-12 |
| ZA852534B (en) | 1986-11-26 |
| AU4081185A (en) | 1985-10-10 |
| PL252743A1 (en) | 1986-09-09 |
| JPS60226880A (ja) | 1985-11-12 |
| DK147285A (da) | 1985-10-05 |
| FI851351A0 (fi) | 1985-04-03 |
| ZW6785A1 (en) | 1986-11-12 |
| ES550466A0 (es) | 1987-03-01 |
| ES550467A0 (es) | 1987-03-01 |
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