ES8606348A1 - Un metodo para preparar un derivado de 9-bencilpurina - Google Patents

Un metodo para preparar un derivado de 9-bencilpurina

Info

Publication number
ES8606348A1
ES8606348A1 ES541948A ES541948A ES8606348A1 ES 8606348 A1 ES8606348 A1 ES 8606348A1 ES 541948 A ES541948 A ES 541948A ES 541948 A ES541948 A ES 541948A ES 8606348 A1 ES8606348 A1 ES 8606348A1
Authority
ES
Spain
Prior art keywords
compounds
hydrogen
ethyl
methyl
iii
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541948A
Other languages
English (en)
Other versions
ES541948A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES541948A0 publication Critical patent/ES541948A0/es
Publication of ES8606348A1 publication Critical patent/ES8606348A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 9-BENCILPURINA, Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R5 Y R6 PUEDE SER VARIOS TIPOS DE RADICALES; Y R7 REPRESENTA HIDROGENO O FLUOR. CONSISTE EN LA REACCION DE UNA AMINA DE FORMULA HNR5R6 CON UN COMPUESTO DE FORMULA (II), EN LAS QUE X REPRESENTA UN GRUPO ELIMINANTE Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE POLAR, A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y 180JC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE TRASTORNOS DEL SISTEMA NERVIOSO CENTRAL.
ES541948A 1984-04-04 1985-04-03 Un metodo para preparar un derivado de 9-bencilpurina Expired ES8606348A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848408615A GB8408615D0 (en) 1984-04-04 1984-04-04 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
ES541948A0 ES541948A0 (es) 1986-04-16
ES8606348A1 true ES8606348A1 (es) 1986-04-16

Family

ID=10559131

Family Applications (3)

Application Number Title Priority Date Filing Date
ES541948A Expired ES8606348A1 (es) 1984-04-04 1985-04-03 Un metodo para preparar un derivado de 9-bencilpurina
ES550467A Expired ES8802052A1 (es) 1984-04-04 1985-12-27 Un metodo para preparar derivados de 9-bencilpurina
ES550466A Expired ES8802051A1 (es) 1984-04-04 1985-12-27 Un metodo para preparar derivados de 9-bencilpurina

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES550467A Expired ES8802052A1 (es) 1984-04-04 1985-12-27 Un metodo para preparar derivados de 9-bencilpurina
ES550466A Expired ES8802051A1 (es) 1984-04-04 1985-12-27 Un metodo para preparar derivados de 9-bencilpurina

Country Status (14)

Country Link
EP (1) EP0157637A3 (es)
JP (1) JPS60226880A (es)
AU (1) AU4081185A (es)
DD (1) DD233843A5 (es)
DK (1) DK147285A (es)
ES (3) ES8606348A1 (es)
FI (1) FI851351L (es)
GB (1) GB8408615D0 (es)
GR (1) GR850838B (es)
HU (1) HUT37429A (es)
IL (1) IL74803A0 (es)
PL (1) PL252743A1 (es)
ZA (1) ZA852534B (es)
ZW (1) ZW6785A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204353A (en) * 1987-04-07 1993-04-20 Ciba-Geigy Corporation 3-benzyl-3H-1,2,3-triazolo[4,5-d]pyrimidines, compositions thereof, and method of treating epilepsy therewith
EP0363320A3 (de) * 1988-10-06 1991-11-21 Ciba-Geigy Ag Substituierte 9H-Purine
US5166209A (en) * 1989-04-21 1992-11-24 Burroughs Wellcome Co. Pharmacologically active compounds
GB8913011D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Anticonvulsant pyrazines
US5240937A (en) * 1990-04-20 1993-08-31 Burroughs Wellcome Co. Pharmaceutically active triazolopyridine compounds
ATE243697T1 (de) * 1995-12-08 2003-07-15 Pfizer Substitutierte heterozyclische derivate als crf antagonisten
US6992188B1 (en) 1995-12-08 2006-01-31 Pfizer, Inc. Substituted heterocyclic derivatives
US6107300A (en) * 1996-03-27 2000-08-22 Dupont Pharmaceuticals Arylamino fused pyrimidines
US6648453B2 (en) 1997-07-15 2003-11-18 Silverbrook Research Pty Ltd Ink jet printhead chip with predetermined micro-electromechanical systems height
US20230279006A1 (en) * 2020-07-08 2023-09-07 Klotho Therapeutics, Inc. Novel compounds and methods for increasing klotho gene expression

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3846426A (en) * 1971-03-03 1974-11-05 Int Minerals & Chem Corp 6-amino-9-(substituted benzyl) purines and their n{11 oxides
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
GB1547214A (en) * 1977-08-09 1979-06-06 Merck & Co Inc Purine derivatives
US4189485A (en) * 1977-08-23 1980-02-19 Takeda Chemical Industries, Ltd. Purine derivatives
US4900826A (en) * 1981-09-24 1990-02-13 Kohjin Co., Ltd. Process for preparing N6,9-disubstituted adenine

Also Published As

Publication number Publication date
ES541948A0 (es) 1986-04-16
ES8802051A1 (es) 1987-03-01
GR850838B (es) 1985-11-25
HUT37429A (en) 1985-12-28
JPS60226880A (ja) 1985-11-12
DK147285A (da) 1985-10-05
EP0157637A3 (en) 1986-11-05
AU4081185A (en) 1985-10-10
FI851351A0 (fi) 1985-04-03
DD233843A5 (de) 1986-03-12
DK147285D0 (da) 1985-04-01
FI851351L (fi) 1985-10-05
IL74803A0 (en) 1985-07-31
ES550466A0 (es) 1987-03-01
ZA852534B (en) 1986-11-26
ES550467A0 (es) 1987-03-01
GB8408615D0 (en) 1984-05-16
EP0157637A2 (en) 1985-10-09
ZW6785A1 (en) 1986-11-12
ES8802052A1 (es) 1987-03-01
PL252743A1 (en) 1986-09-09

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